Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed...

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May 27, 2014 1 RIVA 2014 COMPLETE YOUR AGILENT TOUR Better Connections with Agilent Ken Lynam CSD R&D/Applications Chemist, Wilmington, DE USA

Transcript of Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed...

Page 1: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

May 27, 2014

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RIVA 2014 COMPLETE YOUR AGILENT TOUR

Better Connections with Agilent Ken Lynam CSD R&D/Applications Chemist, Wilmington, DE USA

Page 2: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

GC column installation is a challenge

A routine, basic procedure, but

not easy to do

Plus – a minimum of 2 chances

to get it wrong !

• Very small parts

• Wrenches in cramped, dark

space

Even when done correctly,

fittings are known to be prone

to leaks

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Page 3: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

How do you make leak free column connections? Start with the right tools and supplies

Assemble the parts

• Column Nuts

• Material : stainless – but need brass for MS interface

• Finger tight available for graphite ferrules

• Choice of right ferrules

Make a good clean cut – every time

• After ferrule is installed

• Fused silica tubing cutters : ceramic

• Magnifier to inspect the cut

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Page 4: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

polyimide

Which Capillary Ferrules?

Composition Re-use Max T Use Limitation

Polyimide (Vespel) yes 280 Easy seal Shrink after heating causing leaks after

thermal cycle; isothermal only

Graphite yes 450 Not MS or

ECD

Contamination, leakages – not for

oxygen sensitive detectors

Polyimide/graphite

(85% / 15%)

limited 350 MS Still shrink after thermal cycles creating

leaks; need to retighten regularly

Flexible metal no 450 CFT … May not seal well with damaged rough

surfaces

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polyimide/graphite graphite

“Long” ferrules for MS transfer lines and MS interface nut

“Short” ferrules for inlet and detector configurations on Agilent GC’s

flexible metal

Page 5: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Graphite / polyimide capillary ferrules

… leak after normal temperature program runs

Studies show the leaking continues with use of the ferrules

Not just the first one or two runs

Frequent re-tightening of the fitting with graphite/polyimide

ferrules is needed to maintain a leak-free seal – and system

performance and productivity

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Page 6: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Agilent Self Tightening Column Nuts

Designed for use with short graphite/polyimide blend ferrules –

both at the inlet and the MS interface – so only one type of ferrule

needed for both ends of the column!

Short ferrule exposes more thread of the fitting for better sealing

For mass spec transfer line For inlet or detector

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Page 7: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Benefit of Self-Tightening Column nuts

Without retightening,

the baseline remains

flat after 400 runs

with no indication of

leaks when using the

Self Tightening

column nuts

Take you from this….

…. to this!

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Page 8: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Better Connections 1: Glass connectors

• UI Chemistries applied to

press fit connectors

• Improved inertness

performance

• Best in class inertness

• Easier to use than competitors

because you can see it work!

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Page 9: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Comparison UI pressfit to presstight Siltek deactivated

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11.51110.5109.598.587.576.565.554.543.532.521.510.5

28

26

24

22

20

18

16

14

12

10

8

6

4

2

0

-2

-4

-6

-8

-10

-12

-14

-16

-18

-20

-22

-24

-26

-28

1.33

1.41

1.85

2.31

2.62

2.85

2.97

3.76

4.17

6.22

6.77

7.51

8.459.42

10.38

1.36

1.44

1.71

1.88

2.36

2.67

2.91

3.03

3.82

4.25

6.326.89 7.63

8.599.57

10.55

RT [min]

GC28B_CONNECTOR-005_VIM2_9253640_CP4787_lot723838_2_1_1.DATAGC28B_CONNECTOR-007_VIM2_9253640_UI_pressfit_RG_1_1.DATA

pA

XOffset : 0.2

YOffset : -30

1

2

3 4

5

6 7

8

9 10 11

12 13 14

UI pressfit

Presstight, Siltek

deactivated #20480

Excellent inertness, but

Siltek deactivated

connector not transparant

Testing 86 hrs 325°C:

PASSED

Page 10: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Better Connections 2: CFT is best in class

“The un-purged splitter is so much better than a glass “Y”

splitter because it was simple to put together. The new

ferrules really made it easy. Since we installed it there have

been no leaks and the performance is excellent. These

results will be in my thesis”

Forensics Toxicology Graduate Student

Pennsylvania State university

• Ultimetal Plus deactivation for

superior inertness

• Easy to assemble

• They don’t leak!

• New pricing

• Kitted for easy ordering

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Page 11: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Ultimetal Plus Tubing and Fittings

• 0.53 and 0.25 mm ID guards and

transfer lines

• Metal fittings (unions, tee’s and

nuts)

• Steel tubing (1/16”, 1/8”, ¼”)

• Ultimetal Plus fused silica guard

columns

Superior performance for

configured systems in HPI,

environmental and other

application spaces.

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Page 12: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

5.254.84.64.44.243.83.63.43.232.82.62.42.221.81.61.41.210.80.60.40.20

270

260

250

240

230

220

210

200

190

180

170

160

150

140

130

120

110

100

90

80

70

60

50

40

30

20

10

0

-10

-20

0.69

0.73 0.92

1.141.29

1.37

1.43

1.77

1.96

2.86

3.12

3.44

3.86 4.29 4.73

0.68

0.72 0.91

1.151.30

1.38

1.44

1.80

2.00

2.94

3.20

3.52

3.964.40

4.85

RT [min]

GC38F_UIUM-036_VIM2_CP8944-9294947_6510716_end_2m_10_1.DATAGC38F_UIUM-036_VIM2_CP8944-9294947_MXT 70294-1178464_2m_11_1.DATA

pA

XOffset : 0

YOffset : 140

Guards:Tandem test 2 m 0.53mm ID pieces using a VIM2 mix

12

CF 4.7 mL/min H2

oven 60°C

14 13 12

11 10

9

8

7 6

5

4 3

Conclusion:

UltiMetal Plus Guard gives equal or better inertness compared to MTX Biodiesel T G .

Great results for inertness.

Agilent UltiMetal Plus Guard

MXT Biodiesel TG Guard

4-picoline

Avg corr. As 6.6

Avg. Abs. recovery 103%

4-picoline

Avg corr. As 2.3

Avg. Abs. recovery 103%

May 27, 2014

VIM2 (split 1:75)

# Compound ng

1 Methane

2 Propionic acid 1

3 iso-Butyric acid 1

4 n-Butyric acid 1

5 Octene 0.5

6 Octane 0.5

7 1-Nitrobutane 1

8 4-Picoline 2

9 Trimethyl Phosphate 5

10 1,2-Pentanediol 2

11 Propylbenzene 1

12 1-Heptanol 1

13 3-Octanone 1

14 Decane 1

Page 13: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

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May 27, 2014

UltiMetal on the outside

for improved inertness

Bare Steel

Testing the outside of a metal capillary for

24 hrs at 450°C:

Metal outside

of the column

in flow path

INLET

CPM union, inert

Metal outside of the column in flow

path

Fleximetal ferrule

Invention disclosure filed.

Page 14: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Making Better GC Connections

• Select supplies appropriate for your instrument and

application

• Follow recommended assembly process

• Maximize productivity by using innovative tools and supplies

Column Installation Pre-swaging tools

Self Tightening column nuts

Ultra Inert Press Fit connectors

UltiMetal Plus Flexible metal ferrules

UltiMetal Plus tubing and fittings

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Page 15: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

RIVA 2014 COMPLETE YOUR AGILENT TOUR

May 27, 2014

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It’s a Great Story!

Thanks to great innovation and product development…

What started with the Inert Flowpath program last year is now

expanding to include all of the flow components in the GC.

This means challenging applications are now EASIER and

FASTER to implement, delivering superior performance that

translates to INCREASED UPTIME and FASTER

LABORATORY OPERATIONS.

Page 16: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

NOW IT’S EASIER THAN EVER TO GET RELIABLE GC RESULTS THROUGH BETTER GC CONNECTIONS

FROM AGILENT

www.agilent.com/chem/betterGCconnections

Order the poster… View the video…

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Page 17: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Acknowledgements

• Agilent colleagues

• Lindy Miller

• Yun Zou

• Gary Lee

• Paul Trip

• Roger Firor

• You for your kind attention

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Page 18: Agilent Self-Tightening Column Nut · 2016. 9. 4. · Agilent Self Tightening Column Nuts Designed for use with short graphite/polyimide blend ferrules – both at the inlet and the

Questions?

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