Agilent MSD Productivity ChemStation for GC and GC/MSD … · The Agilent MSD Productivity...

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The Agilent MSD Productivity ChemStation is a full-featured 32-bit integrated GC/MS soft- ware application for all the tasks associated with GC/MS data acquisition, data analysis, and reporting. Supported on Windows Vista and XP®, the MSD Productivity ChemStation software controls multiple GC/MSs and GCs and consists of the following functionality (Figure 1): Agilent MSD Productivity ChemStation for GC and GC/MSD Systems Integrated instrument control (of the GC, MSD, ALS, head- space samplers, and PAL autosamplers) Data analysis (for GC, MS, and combined GC/MS data) Integration with Agilent OpenLAB Enterprise Content Manager (ECM) High-performance synchro- nous SIM/Scan and Auto- matic SIM/Scan Setup Gain Normalized Autotune SemiQuant eMethods Custom reports Enhanced data analysis tools Macro programming User-defined security Software validation tools Figure 1. The MSD Productivity ChemStation is many applications in one. From sample introduction to the final report % the soft- ware operates seamlessly to meet your application requirements.

Transcript of Agilent MSD Productivity ChemStation for GC and GC/MSD … · The Agilent MSD Productivity...

Page 1: Agilent MSD Productivity ChemStation for GC and GC/MSD … · The Agilent MSD Productivity ChemStation is a full-featured 32-bit integrated GC/MS soft-ware application for all the

The Agilent MSD ProductivityChemStation is a full-featured32-bit integrated GC/MS soft-ware application for all the tasksassociated with GC/MS dataacquisition, data analysis, andreporting. Supported on Windows Vista and XP®, theMSD Productivity ChemStationsoftware controls multipleGC/MSs and GCs and consists ofthe following functionality(Figure 1):

Agilent MSD Productivity ChemStation forGC and GC/MSD Systems

• Integrated instrument control(of the GC, MSD, ALS, head-space samplers, and PALautosamplers)

• Data analysis (for GC, MS,and combined GC/MS data)

• Integration with AgilentOpenLAB Enterprise ContentManager (ECM)

• High-performance synchro-nous SIM/Scan and Auto-matic SIM/Scan Setup

• Gain Normalized Autotune

• SemiQuant

• eMethods

• Custom reports

• Enhanced data analysis tools

• Macro programming

• User-defined security

• Software validation tools

Figure 1. The MSD Productivity ChemStation is many applications in one. From sample introduction to the final report %% the soft-ware operates seamlessly to meet your application requirements.

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Integration with AgilentOpenLAB ECM

Data archival and retrieval isenabled seamlessly through the integration of GC/MSDChemStation and Agilent Open-LAB ECM. The GC/MSD Chem-Station integrates common ECMfunctions within its user inter-face, allowing organizations tostore and organize data frommultiple instruments in one cen-tral secure repository withoutdisrupting current workflow(Figure 2).

Improve Every Analysiswith Gain!

An important feature of theGC/MSD Productivity ChemSta-tion is Gain Normalized Meth-ods. Setting GAIN in yourmethods (Figure 3) provides:

• Better signal reproducibilityin your analyses!

• Simple “Tune and Use” methods!

• Better consistency betweenevery MSD instrument inyour lab!

• Better method optimizationfor sensitivity and linearity!

• More benefits from the newTriple-Axis Detector!

High-Performance Synchronous SIM/Scan

High-Performance SynchronousSIM/Scan is an acquisition modepossible on the 5975C SeriesMSD that enables collection ofboth SIM data and full scan datain a single run. SIM dwell timeas low as 1 millisecond allowsextremely narrow 600 millisec-ond chromatographic peaks tobe acquired in SIM/Scan.

Automated Selected IonMonitoring (SIM) andSIM/Scan SetupComplex SIM and SIM/Scanmethods are difficult to set upmanually. Retention times (RTs)and ions must be entered foreach compound.

The AutoSIM Setup simplifiesthis process for you by creatingan acquisition method with RTs,selected ions or ion ranges, andidentification ratios from anexisting quantitation method(Figure 4).

Figure 2. Access common ECM functionality, like open, save, and search data,directly from the GC/MSD ChemStation.

Figure 4. AutoSIM setup creates aSIM or SIM/Scan methodautomatically from anyexisting full scan method.

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Figure 3. Setting GAIN in your methods will provide optimized and consis-tent performance from instrument to instrument.

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Figure 5. SemiQuant: a novel way to estimate compound concentration without thehassle of calibration.

SemiQuantSemiQuant allows you to esti-mate a compound’s concentra-tion based on the response for asimilar compound, such as ahomolog or congener. Entiremethods can be easily convertedto SemiQuant by using GlobalSemiQuant, while Specific Semi-Quant allows you to add Semi-Quant compounds to any method(Figure 5). Quantitation reportshandle the SemiQuant com-pounds separately from targetcompounds for easy identifica-tion within reports (Figure 1).

Four Application Modes:Enhanced, EnviroQuant,DrugQuant, and AIG

The Agilent MSD ProductivityChemStation can be configuredfor general Enhanced Quantita-tion, EnviroQuant, DrugQuant,and Aromatics in Gasoline modes.Each of these modes providesadditional entries or reports specific to these applications.

eMethodseMethods is short for electronicmethods % a quick and easy wayto obtain packaged applicationsolutions from Agilent or toshare and distribute your ownpersonal applications.

eMethods allow you to easilypackage and transfer methodsbetween the Agilent 5973 Seriesand 5975C Series MSDs.

You may also download any newAgilent eMethod from the Agilent Web site and import thatmethod to your Agilent 5975C or5973 Series MSD and receive theentire method without anymanual editing errors.

7.60 7.65 7.70 7.75 7.80 7.85 7.90 7.95 8.00

Time

8.05 8.10 8.15 8.20 8.25 8.30 8.350

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TIC: RTLOCK3.D

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8.098.01 8.32

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After column trimming

7.60 7.65 7.70 7.75 7.80 7.85 7.90 7.95 8.00

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TIC: RTLOCK5.D

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After relocking with RTL

TIC: RTLOCK3.D

7.89

8.018.09

8.32

7.60 7.65 7.70 7.75 7.80 7.85 7.90 7.95 8.00

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Figure 6. RTs remain constant with RTL.

RTL

RTL methods will maintain con-stant RTs % eliminating the needto edit method RTs after maintenance or when transfer-ring a method to another instrument.

By making an adjustment in theinlet pressure, the RTs on agiven system can be closelymatched to those on anothersystem. Figure 6 shows how theshifts in RT are fixed by RTLwhen a column is changed.

Chinese and JapaneseLanguages

In addition to English, the MSDProductivity ChemStation soft-ware, and online help forEnhanced Mode, as well as thehardware and software manualsare available in Japanese andSimplified Chinese.

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www.agilent.com/chem

Environmental Applications

• Autotune for DFTPP/BFB compliance

• Hazardous chemical RTLdatabase

• Pesticide and endocrinedisruptor RTL spectral andRT database

• Polynuclear aromatic hydro-carbons (PAH) RTL spectraland RT database

• Volatile organic compound(VOC) RTL spectral and RTdatabase

• Polychlorinated biphenyls(PCB) congener RTL spec-tral and RT database

• USEPA CLP-like reports,including tentatively identified compounds, mul-tisample, spike, and otherQC reports

Food Applications

• FAME RTL spectral and RTdatabase

• Flavors RTL spectral and RTdatabase

• Pesticide and endocrine disruptor RTL spectral andRT database

Drugs of Abuse/Forensic Applications

• Forensic toxicology RTLspectral and RT database

• Intelligent sequencing

Petrochemical Applications

• Reformulated gasolineanalyses via ASTMD5769-95

Pharmaceutical Applications

• Weighted calibration basedon concentration

• Optional 21 CFR Part 11compliance software (Agilent MSD Security ChemStation, G1732AA)

• Optional IQ/OQ/PV services

System Requirements

The MSD Productivity ChemSta-tion supports the following products:

• 5973 (LAN only) and 5975Series MSDs

• 7890A Series GCs, 6890 SeriesGCs, and 6850 GC

• 7683 Series ALS

• G1888 Headspace Samplers

• PAL Autosamplers

The MSD Productivity ChemSta-tion supports the following oper-ating systems:

• Windows XP Pro SP2

• Windows Vista Business

Instrument Control• Up to four instruments

(maximum two MSDs)

• Controls instruments via stan-dard LAN communications

• Autotunes for EI, PCI, NCI,DFTPP, BFB, and max sensitivity

• Sample list can be downloaded from LIMS

• Integrated control of the head-space samplers and PALautosamplers

Qualitative Analysis• PBM search algorithm

with NIST search optional

• Optional libraries includeNIST05, Wiley 8th, PMW drug,and Stan pesticide

• Molecular structures(optional)

• RT and spectral database forpesticide and endocrine disruptor (optional)

Quantitative Analysis• Capacity for more than

2,000 compounds

• Twenty levels of calibration

• GC-optimized and MS-optimized integrators

• Extensive curve fitting: linear,quadratic, average responsefactor, and weighted

Optional SoftwareDeconvolution Reporting Software(G1716AA) An application fortarget compound analyses thatutilizes Agilent MSD Productiv-ity ChemStation, NISTAMDIS_32, and the NIST MSSearch Program.

Headspace Software Control forMSD (G2923AA) Provides inte-grated software control of theheadspace samplers.

PAL Autosampler Control for MSDChemStation (G3384AA) Providesintegrated software control forthe PAL autosampler.

MSD Security ChemStation(G1732AA) A secured softwaresystem for data acquisition, dataprocessing, and reporting ofGC/MS data in laboratories regu-lated by FDA 21 CFR Part 11.

For More InformationFor more information on ourproducts and services, visit ourWeb site atwww.agilent.com/chem.

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Agilent shall not be liable for errors contained herein or

for incidental or consequential damages in connection

with the furnishing, performance, or use of this

material.

Information, descriptions, and specifications in this

publication are subject to change without notice.

© Agilent Technologies, Inc. 2008

Printed in the USA

March 2008

5989-6113EN