AFAMS Genitourinary System and Sex Hormones EO 003.01 Part 21.
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Transcript of AFAMS Genitourinary System and Sex Hormones EO 003.01 Part 21.
AFAMS
Genitourinary System and Sex Hormones
EO 003.01 Part 21
AFAMS
Overview of Lesson(Insert Dari)
Gynecological Anti-infectives and anti-septics
Other Gynecologicals
Sex hormones and modulators of the genital system
Urologicals- Antispasmodics- Drugs used in benign prostatic
hypertrophy
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What I need to know as a pharmacy technician(Insert Dari)
In this lecture we will cover the drugs listed in the ANA Formulary which are classified according to the ATC system under
(G) Genitourinary and Sex Hormones
For each of these medications/classes students must obtain an understanding of:
(1) Mechanism of Action
(2) Indications (Uses)
(3) Efficacy
(4) Side Effects
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Gynecological Anti-infectives and Antiseptics
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Mechanism of Action Metronidazole - interferes with protein synthesis of the yeast. Clotrimazole – interferes with cell membrane synthesis of the yeast.Nystatin – Degrades the cell wall of the yeast.
Indication (Uses) Used to treat vaginal yeast infections.
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Metronidazole, Clotrimazole and Nystatin(Insert Dari)
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Side Effects May cause some minor skin irritation.
Important Points • For external use only.• Apply at bedtime.
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Metronidazole, Clotrimazole and Nystatin(Insert Dari)
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Oxytocics(Insert Dari)
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Methylergonovine(Insert Dari)
Mechanism of Action Increases the tone, rate and strength of contractions of the smooth muscles of the uterus.
Indication (Use) To stop bleeding that occurs after a birth.
Side Effects•High blood pressure•Headache•Upset stomach
Important PointsAdministered intravenously.
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Sex hormones and modulators of the genital system(Insert Dari)
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Ovaries
Produce estrogen, which promotes the development of female sex characteristics and controls the menstrual cycle.
Also produces progesterone, which controls development of the endometrium (layer of tissue/blood lining the inside the uterus which supports a growing fetus and is shed during menstruation).
Hormones of the female genital system(Insert Dari)
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Noethisterone and Progesterone(Insert Dari)
Mechanism of ActionBoth are synthetic forms of the naturally occuring hormone progesterone.
Indications (Use) Abnormal menstrual symptoms (very heavy bleeding, severe pain etc.). Can be used in the treatment of infertility. It is used to stop endometrial changes in women after menopause, who are getting estrogen therapy.
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Noethisterone and Progesterone(Insert Dari)
Side Effects• Feeling dizzy. Rise slowly
over a few minutes when sitting or lying down.
• Headache.• Belly pain.• Upset stomach or throwing
up. • Enlarged breasts/breast
pain.• Muscle pain.• Joint pain.
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Urologicals(Insert Dari)
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Flavoxate(Insert Dari)Mechanism of action
Relaxes the muscles of the bladder.
Indication (Use) Is used to treat an overactive bladder. This means that a person is having to urinate more frequently than normal to the point that it interrupts their ability to function.
Side Effects
Headache.
•Feeling sleepy.
•Dizziness.
•Blurred eyesight.
•Dry mouth.
•Upset stomach.
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Tamsulosin(Insert Dari)Mechanism of action
Relaxes the smooth muscle in the bladder neck and prostate causing an improvement of urine flow.
Indication (Use) Benign prostatic hypertrophy (BPH) – enlarged prostate. Kidney stone
Side Effects• Feeling dizzy. Rise slowly
over a few minutes when sitting or lying down.
• Headache.• Nose stuffiness.• Change in sex ability
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What is benign prostatic hypertrophy? (Insert Dari)
Benign prostatic hypertrophy (BPH) is an enlarged prostate.
The prostate is a gland that surrounds the urethra (the tube that carries urine from the bladder out through the penis).
Symptoms include:
Needing to urinate often, especially at night
Having trouble starting to urinate (this means that you might have to wait or strain before urine will come out)
Having a weak urine stream
Leaking or dribbling urine
Feeling as though your bladder is not empty even after you urinate
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What is a kidney stone? (Insert Dari) Kidney stones are just what
they sound like: Small stones that form inside the kidneys.
They form when salts and minerals that are normally in the urine build up and harden.
Kidney stones usually get carried out of the body when you urinate. But sometimes they can get stuck on the way out. If that happens, the stones can cause:• Pain in your side or in the lower part of your belly• Blood in the urine (which can make urine pink or red)• Nausea or vomiting • Pain when you urinate • The need to urinate in a hurry
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Questions?(Insert Dari)
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In-class Assignment(Insert Dari)
This assignment will consist of 3 questions which are to be completed individually. Once complete the instructor will review the answers with the class.
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1.Which of the following is NOT used to treat a yeast infection?
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A) Clotrimazole
B) Metronidazole
C) Progesterone
D) Nystatin
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1.Answer: Which of the following is NOT used to treat a yeast infection?
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A) Clotrimazole
B) Metronidazole
C) Progesterone
D) Nystatin
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2. Which of the follow is NOT a condition that is treated with progesterone?
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A. Abnormal menstrual symptoms (very heavy bleeding, severe pain etc.).
B. Can be used in the treatment of infertility.
C. It is used to stop endometrial changes in women after menopause, who are getting estrogen therapy.
D. All of the above
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2. Answer: Which of the follow is NOT a condition that is treated with progesterone?
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A. Abnormal menstrual symptoms (very heavy bleeding, severe pain etc.).
B. Can be used in the treatment of infertility.
C. It is used to stop endometrial changes in women after menopause, who are getting estrogen therapy.
D. All of the above
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3. Which of the following is a side effect of flavoxate? (Insert Dari)
A) Dry mouth
B) Decreased ability to urinate
C) Inability to sleep
D) Stuffy nose
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3. Answer: Which of the following is a side effect of flavoxate?
(Insert Dari) A) Dry mouth
B) Decreased ability to urinate
C) Inability to sleep
D) Stuffy nose
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