Advances in experimental medicine and biology. Volume 178. Phosphate and mineral metabolism
1
796 Book reviews Neurochemical techniques in insect research---Edited by H. and blood pressure; minerals and myopathies; clinical BREEK and T. A. MILLER. 324 pp. 19XS. Springer. Berlin. topics; NMR study of phosphorus metabolism; NMR in DMlh9. nephrology. Insects provide ideal material for experimental research and the present volume gives practical details of screening and assays for neurotransmitters in the insect CNS: assays for biogenic amines, peptides, cyclic nucleotides; binding stud- ies and receptors; study of ion transport: recombinant DNA techniques: production of monoclonal antibodies to neuronal antigens; detection of neurotoxins: culturing in- sect nerve cells in virro, and the study of insect energy metabolism. Biomembranes. Volume 12. Membrane fluidity---Edited by M. KATES and L. A. MAN%)%. 693 pp. 1984. Plenum Press, New York. $85. Sul%cient practical details are provided so that a graduate student could carry out the experimental procedure as part of a project. The techniques will also be very useful to more advanced research workers who wish to extend or up-date their techniques. The volume is a valuable addition to the Springer Series in Experimental Entomology. Environmental Physiology and Biochemistry of Iusects- Edited by K. H. HOFFMAN. 296 pp. 1985. Springer, Berlin. DM98. This very useful multi-author volume provides excellent review articles on metabolic and enzyme adaptation to temperature. temperature and insect development, environ- mental aspects of insect dormancy, metabolic energy ex- penditure and its hormonal regulation. anaerobic energy metabolism, respiration and respiratory water loss. water and salt relations. color and color change, and environ- mental aspects of insect bioluminescence. The references to all the chapters are collected at the end of the hook and printed with full titles of the papers. There is a good subject and species index. The reviews clearly show how insects are able to adapt their physiology. endocrinology and biochemistry to a wide range of environ- mental conditions to become the most successful group of animals on land. in air and in the water. The aim of the present volume is to bring together current research and opinions on membrane fluidity. The chapters deal with the following topics: Physical studies of mem- brane fluidity: Thermal analysis of membranes; Fluo- rescence polarization studies of membranes; Where do we go from here? Confor~~tion and motional properties of lipids in membranes as determined by deuterium magnetic resonance; flluidity of membranes in the presence of drugs and inhibitors: Lipid bilayet stability; Membrane lipid fluidity and phase state in relation to bacterial and my- coplasma growth at various temperatures; Thermal control of fatty acid synthetases in bacteria; Regulation of mem- brane fluidity in bacteria by acyl chain length changes: Control of membrane fluidity in plasmalogen-confining anaerobic bacteria; Regulation of membrane fluidity by lipid desaturases; Regulation of membrane fluidity in Tetrahymena; Control of membrane fluidity in Fusuriun~; Regulation of hepatic phospholipid n-methylation: Fluidity of membrane lipids; Membrane lipid adaptation in yeasts; Dynamic state of membrane lipids: Role of phospholipid head group structure and polarity in control of membrane fusion: Membrane fluidity and receptor function; Gly- cosphingolipid domain formation and lymphocyte activa- tion: Dynamics of membrane lipids during lymphocyte stimulation by mitogens: Membrane permeability in malig- nant porcine hyperthermia. The volume provides a very good summary that will help biochemists, physiologists and pharmacologists understand the rote of lipid fluidity in membrane function and cell activity. Oxidative stress-Edited by H. SIES. 507 pp. 1985. Aca- demic Press, London. 1579. f72. Dahlem workshop reports. Life sciences. Volume 29. The biology of learning--Edited by P. MARLER and H. S. TERRACE. 738 pp. 1984. Springer, Berlin. DM88. Oxidative stress is the disturbance of the pro-oxidant;anti- oxidant systems in favour of the former. The agents involved can be the superoxide anion, or the perhydroxy. hydroxyl, alkoxy, peroxy. radicals. Antioxidant defence systems can involve alpha tocopherol. ascorbate, t?avonoids, beta carotene. urate, plasma proteins. SOD. CSH aeroxidases. catalase. GSSH reductase and many other dhemicals. This multi-author volume discusses radioi- ysis of DNA. organic peroxy free radicals, hydroperoxides and thiol oxidants, quinone-induced oxidative injuries, nitrosoureas. antimalarials, hypoxic and hyperoxic stress. the role of diet. calcium movement. mixed disulphides, lipid peroxidation. red cell oxidative damage, neutrophil granu- locytes, CNS damage, inflammation and tumor promotion in the skin. In this meeting between ethologists, psychologists and physiologists, papers were presented in five main sections; (1) General issues in the biology of learning; (2) In- vertebrate learning; (3) Learning in non-mammalian verte- brates; (4) Learning in non-human mammals; (5) Learning in humans. Readers who would like to find accounts of the learning systems in a range of animals and an analysis of the possible m~hanisms underlying learning will find this book very useful. NATO AS1 series A. Life sciences. Volume 82. Receptor mediated targeting of drugs-Edited by G. GREGORIAIXS, G. POSTE, .J. SENIOR and A. TROUET. 491 pp. 1984. Plenum Press, New York. $79.50. This book links together many instances of cell and tissue damage with the underlying bi~hemicai lesion of oxidative stress and so gives greater understanding of many clinical signs and symptoms. Advances in experimental medicine and biology. Volume 178. Phosphate and mineral metabolism-Edited by S. G. MASSRY. G. MASCHIO and E. Ritz. 485 pp. 1984. Plenum Press. New York. $69.50. The role of phosphate, calcium and magnesium are dis- cussed in this symposium held in Verona. The main sections are: renal handling of phosphate; calcium and magnesium transport: intestinal absorption of phosphate and calcium; topics on bone; minerals, parathyroid hormone Receptor-r~ognizing carriers have recently given promise of targeting onto a specific restricted end organ. Mono- clonal antibodies. receptor-specific proteins and iiposomes have all been used to improve specificity of drug targeting in cancer chemotherapy. Thus, galactosylated serum albu- min, linked by a tetrapeptide arm to daunorubicin, is a promising conjugate for chemotherapy of human hepatoma cells. Polyclonal (anti-human milk fat globule membranes) antibodies could be linked to a toxin and then targeted onto breast cancer cells. Other toxic conjugates discussed are conjugates of epidermal growth factor and asialofetuin. and human transferrin-ricin. The use of liposomes in treatment of Leishmaniasis, Legionnaire’s Disease, thrombus and in diagnostic imaging are also discussed.
Transcript of Advances in experimental medicine and biology. Volume 178. Phosphate and mineral metabolism
796 Book reviews
Neurochemical techniques in insect research---Edited by H. and blood pressure; minerals and myopathies; clinical
BREEK and T. A. MILLER. 324 pp. 19XS. Springer. Berlin. topics; NMR study of phosphorus metabolism; NMR in
DMlh9. nephrology.
Insects provide ideal material for experimental research and the present volume gives practical details of screening and assays for neurotransmitters in the insect CNS: assays for biogenic amines, peptides, cyclic nucleotides; binding stud- ies and receptors; study of ion transport: recombinant DNA techniques: production of monoclonal antibodies to neuronal antigens; detection of neurotoxins: culturing in- sect nerve cells in virro, and the study of insect energy metabolism.
Biomembranes. Volume 12. Membrane fluidity---Edited by M. KATES and L. A. MAN%)%. 693 pp. 1984. Plenum Press, New York. $85.
Sul%cient practical details are provided so that a graduate student could carry out the experimental procedure as part of a project. The techniques will also be very useful to more advanced research workers who wish to extend or up-date their techniques. The volume is a valuable addition to the Springer Series in Experimental Entomology.
Environmental Physiology and Biochemistry of Iusects- Edited by K. H. HOFFMAN. 296 pp. 1985. Springer, Berlin. DM98.
This very useful multi-author volume provides excellent review articles on metabolic and enzyme adaptation to temperature. temperature and insect development, environ- mental aspects of insect dormancy, metabolic energy ex- penditure and its hormonal regulation. anaerobic energy metabolism, respiration and respiratory water loss. water and salt relations. color and color change, and environ- mental aspects of insect bioluminescence.
The references to all the chapters are collected at the end of the hook and printed with full titles of the papers. There is a good subject and species index. The reviews clearly show how insects are able to adapt their physiology. endocrinology and biochemistry to a wide range of environ- mental conditions to become the most successful group of animals on land. in air and in the water.
The aim of the present volume is to bring together current research and opinions on membrane fluidity. The chapters deal with the following topics: Physical studies of mem- brane fluidity: Thermal analysis of membranes; Fluo- rescence polarization studies of membranes; Where do we go from here? Confor~~tion and motional properties of lipids in membranes as determined by deuterium magnetic resonance; flluidity of membranes in the presence of drugs and inhibitors: Lipid bilayet stability; Membrane lipid fluidity and phase state in relation to bacterial and my- coplasma growth at various temperatures; Thermal control of fatty acid synthetases in bacteria; Regulation of mem- brane fluidity in bacteria by acyl chain length changes: Control of membrane fluidity in plasmalogen-confining anaerobic bacteria; Regulation of membrane fluidity by lipid desaturases; Regulation of membrane fluidity in Tetrahymena; Control of membrane fluidity in Fusuriun~; Regulation of hepatic phospholipid n-methylation: Fluidity of membrane lipids; Membrane lipid adaptation in yeasts; Dynamic state of membrane lipids: Role of phospholipid head group structure and polarity in control of membrane fusion: Membrane fluidity and receptor function; Gly- cosphingolipid domain formation and lymphocyte activa- tion: Dynamics of membrane lipids during lymphocyte stimulation by mitogens: Membrane permeability in malig- nant porcine hyperthermia.
The volume provides a very good summary that will help biochemists, physiologists and pharmacologists understand the rote of lipid fluidity in membrane function and cell activity.
Oxidative stress-Edited by H. SIES. 507 pp. 1985. Aca- demic Press, London. 1579. f72.
Dahlem workshop reports. Life sciences. Volume 29. The biology of learning--Edited by P. MARLER and H. S. TERRACE. 738 pp. 1984. Springer, Berlin. DM88.
Oxidative stress is the disturbance of the pro-oxidant;anti- oxidant systems in favour of the former. The agents involved can be the superoxide anion, or the perhydroxy. hydroxyl, alkoxy, peroxy. radicals. Antioxidant defence systems can involve alpha tocopherol. ascorbate, t?avonoids, beta carotene. urate, plasma proteins. SOD. CSH aeroxidases. catalase. GSSH reductase and many other dhemicals. This multi-author volume discusses radioi- ysis of DNA. organic peroxy free radicals, hydroperoxides and thiol oxidants, quinone-induced oxidative injuries, nitrosoureas. antimalarials, hypoxic and hyperoxic stress. the role of diet. calcium movement. mixed disulphides, lipid peroxidation. red cell oxidative damage, neutrophil granu- locytes, CNS damage, inflammation and tumor promotion in the skin.
In this meeting between ethologists, psychologists and physiologists, papers were presented in five main sections; (1) General issues in the biology of learning; (2) In- vertebrate learning; (3) Learning in non-mammalian verte- brates; (4) Learning in non-human mammals; (5) Learning in humans.
Readers who would like to find accounts of the learning systems in a range of animals and an analysis of the possible m~hanisms underlying learning will find this book very useful.
NATO AS1 series A. Life sciences. Volume 82. Receptor mediated targeting of drugs-Edited by G. GREGORIAIXS, G. POSTE, .J. SENIOR and A. TROUET. 491 pp. 1984. Plenum Press, New York. $79.50.
This book links together many instances of cell and tissue damage with the underlying bi~hemicai lesion of oxidative stress and so gives greater understanding of many clinical signs and symptoms.
Advances in experimental medicine and biology. Volume 178. Phosphate and mineral metabolism-Edited by S. G. MASSRY. G. MASCHIO and E. Ritz. 485 pp. 1984. Plenum Press. New York. $69.50.
The role of phosphate, calcium and magnesium are dis- cussed in this symposium held in Verona. The main sections are: renal handling of phosphate; calcium and magnesium transport: intestinal absorption of phosphate and calcium; topics on bone; minerals, parathyroid hormone
Receptor-r~ognizing carriers have recently given promise of targeting onto a specific restricted end organ. Mono- clonal antibodies. receptor-specific proteins and iiposomes have all been used to improve specificity of drug targeting in cancer chemotherapy. Thus, galactosylated serum albu- min, linked by a tetrapeptide arm to daunorubicin, is a promising conjugate for chemotherapy of human hepatoma cells. Polyclonal (anti-human milk fat globule membranes) antibodies could be linked to a toxin and then targeted onto breast cancer cells. Other toxic conjugates discussed are conjugates of epidermal growth factor and asialofetuin. and human transferrin-ricin. The use of liposomes in treatment of Leishmaniasis, Legionnaire’s Disease, thrombus and in diagnostic imaging are also discussed.
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