BY ,

S.RAMYABHARATHI

11BBC031

ADULT STEM CELL THERAPY

Adult Stem Cell

Undifferentiated Cells

Found throughout the body after embryonic

development

Multiply by cell division to replenish dying cells

Regenerate Damaged Tissues.

Types of Adult Stem Cells

Hematopoietic

Mammary

Mesenchymal

Neural

Endothelial

Olfactory

Neural crest

Testicular

Properties

Defining properties - self-renewal & potency

Lineage

Signaling pathways

Multidrug resistance

Plasticity / Transdifferentiation

Location of Adult Stem Cell

Identified in many organs and tissues -

Brain, Bone marrow , Peripheral blood, Blood

vessels, Skeletal muscle, Skin, Teeth, Heart, Gut,

Liver, Ovarian epithelium and Testis

Adult Stem Cell Therapies

The therapies require a stem cell source of the

specific lineage and harvesting or culturing them

up to the numbers required is a challenge.

Regenerative Medicine

Process of creating living, functional tissues to repair

or replace tissue or organ function lost due to age,

disease, damage, or congenital defects

It helps to produce extended healthy longevity,

Potential of Adult Stem Cells

Treating LeukemiaLeukemia results when white blood cells made in

bone marrow begin to grow and function abnormal

When chemotherapy cannot solve the problem, doctors turn to bone marrow transplants.

Limitations of adult stem cell

The isolation of some types of ASC.

Where a person suffers from a genetic disorder or

some types of cancers, ASC isolated from that

individual will retain the damaging genetic alterations

underlying the disease and so be of little therapeutic

value

Unambiguous identification is difficult

Maintenance in culture is difficult

advantages

Natural

Safe and effective

Positive side effects

Positive results

THANK YOU