Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of...
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Transcript of Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of...
Adrenal Medulla.
Prof. K. Sivapalan
08-01-14 Adrenal Medulla. 2
Strtucture.
• Location- centre of adrenal gland and paravertibral ganglia.
• Blood supply - cortical- sinusoids into medulla and some arterioles.
• Nerve supply- pre ganglionic sympathetics.
08-01-14 Adrenal Medulla. 3
Effects of Catecholamines• glycogenolysis- liver,muscle.• gluconeogenisis.• lipolysis- adipose tissue.• potassium- release increased in liver
[initial rise], entry increased in muscle [prolonged fall].
• increases- metabolic rate, calorie genesis, alertness, anxiety, fear.
• reduces- proteolysis in muscle, insulin secretion.
08-01-14 Adrenal Medulla. 4
Differences.
08-01-14 Adrenal Medulla. 5
Regulation of Secretion.
• Sympathetic activity.• Sleep:- very low.• Rest:- less• Increased in: hypoxia, asphyxia,
acidaemia, hypoglycaemia, hypothermia, hypotension, haemorrhage, exercise, fear, anger, pain, sexual excitement.
• Stress:- maximum.