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Vaccine for treatment ofalcohol addiction
Moscow – 2014
Alarm!
Литры на человека
Every 5-th man and 6% of women all over the world die in result of alcohol consumption
Officially: in Russia there are more then 2,6 mln. patients with alcoholic
addiction. Real situation: 10 mln. people addicted of alcohol
Alcohol consumption per year
Liters/person
Goal:Peptide vaccine for reduction of alcohol abuse in patients with
alcoholism
«New approaches are very actual in therapy of alcohol addiction. The idea of the vaccine is interesting and promising, such type of drug is
really required»
Maria VinnikovaMD, professor, Deputy Director on scientific and medical work «NSC
of Narcology», Ministry of Health of Russian Federation
Immunomodulator (polyoxidonium)
Peptide 11 a.a.Fragment of ethanol metabolism enzyme
Vaccine
• Market of drugs for addiction treatment was valued at $8.8 billion in 2011
• Compound annual growth rate was 4,9% during period 2004–2011
• The market is projected to reach $12.7 billion and 5.3% CAGR during the 2011–2018 forecast period
(GBI Research, 2012).
Most of patients with chronic alcohol addiction return to narcologist within first six months after treatment!
The main problems of antialcohol drugs – low efficiency and duration of action
Preclinical studies
Efficiency Specificity Safety
2014 20162015 2017
Russian patent
Clinical studiesSale of patent and license on vaccine
production to international
pharmacological company
Expected financing:
• Budgetary funds (FASIE «START»)• Extrabugetary funds (Venture funds)
Aim: 11 mln. rub.
Project scientific adviser:Maksim Lovat’, PhD, senior researcher Lomonosov Moscow State University, Director of
SPF-category vivarium, “Institute of Mitoengeneering of Moscow State University” LLC
TEAM
Vsevolod Pavshintsev, CEO Nikita Mitkin, COO
Medical adviser:
Maria Vinnikova, MD, professor, Deputy Director on scientific and medical work «NSC of Narcology», Ministry of Health of Russian Federation
MSU Science Park. Project partner. Advise
in management and commercial activities