W.DOERFLER P. BÖHM

Adenoviruses :Model and Vectorsin Virus-HostInteractions

Virion-Structure, Viral Replicationand Host-Cell Interactions

1 Virion and Structure I

Molecular Evolution of Adenoviruse sM. BENKÖ, B . HARRACH 3

Novel Partner Proteins of Adenovirus PentonJ . CHROBOCZEK, E . GOUT, A.-L . FAVIER, R. GALINIER 37

Structural Studies on Adenoviruses

C. SAN MARTIN, R. M. BURNETT 57

2 Viral Replication 9 5

The Multifunctional Role of E1A in the Transcriptional

Regulation of CREB/CBP-Dependent Target Gene sD. BROCKMANN, H . ESCHE 9 7

Adenovirus DNA ReplicationH. Liu, J. H. NAISMITH, R.T. HAY 13 1

Regulation of Adenovirus PackagingP. OSTAPCHUK, P. HEARING 16 5

Adenovirus DNA Replication : Protein Priming, Jumping Backand the Role of the DNA Binding Protein DBP

R. N. DE JONG, P. C . VAN DER VLIET, A . B . BRENKMAN 18 7

The Structure and Function of the Adenoviru s

Major Late PromoterC . S . H . YOUNG 213

3 Host-Cell Interactions 25 1

Remodelling of the Host Cell RNA Splicing Machinery Durin g

an Adenovirus Infection

G . AKUSJÄRV I, J. STEVENIN 253

Regulation of mRNA Production by the Adenoviral E1B 55-kD a

and E4 Orf6 Protein s

S . J. FLINT, R .A. GONZALEZ 287

Adenovirus Interaction with Its Cellular Receptor CA R

J. How ITT, C . W. ANDERSON, P. FREIMUTH 33 1

Transactivation of Human cdc2 Promoter by Adenovirus E1A

R. PADMANABHAN, A . TANIMOTO,Y. SASAGURI 36 5

Nuclear Perturbations Following Adenovirus Infection

W.C. RUSSELL, D. A . MATTHEWS 399

The Abortive Infection of Syrian Hamster Cells

with Human Adenovirus Type 1 2

M. HÖSEL, D. WEBB, J. SCHRÖER, W. DOERFLER 41 5

Subject Index 441