ACVP - cdn.ymaws.com€¦ · clinical laboratory medicine, with areas of expertise in comparative...

Mark Ackermann, DVM, PhD, DACVPACVP Secretary/Treasurer

Congratulations to Dr. Anne Barger, who was elected President-elect, and to Dr. Karen Terio, who was elected Councilor! We look forward to your guidance and leadership.

Both Anne and Karen have much experience with the ACVP and have served on the examination committee, which will be helpful in our on-going discussions of the certifying examinations. This fall, for the first time, we administered the Phase II Certifying Examination (CE) on September 8-10 in Ames, Iowa. The Phase II examination contains the traditional three veterinary pathology parts of the CE. The Phase I (General Pathology) was delivered in March at testing centers worldwide.

Another CE-related topic you will be hearing a lot about is a redesign proposal developed by the Certifying Examination Board (CEB). This proposal is currently being reviewed and discussed by Council, Examination Committee members, and training coordinators. In early September, the proposal, along with background information, was sent to all diplomates in the form of an eNewsletter. The eNewsletter will be followed with webinars on September 17 and 24, and a Town Hall meeting on October 20 at the Annual Meeting. Please plan on participating in at least one of the webinars and attending the Town Hall meeting. The changes being proposed are major and warrant your attention and input.

The Annual Meeting (October 17-21) is in Minneapolis, Minnesota, and held jointly between ACVP/ASCVP and the Society of Toxicologic Pathology (STP). The joint meeting brings together a wide variety of interests and spawns a synergy of our main disciplines and areas of

R. Mark Simpson, DVM, PhD, DACVP2015 ACVP President

Progress in Time

Even though we are constantly progressing, it’s my impression that veterinary pathology is currently experiencing an even more clearly evident shift. Economic conditions have stimulated long-term realignment across numerous career sectors. Technology is changing the way people receive information, acquire training, and conduct the work that they do. In veterinary medicine, other clinical specialties have surpassed pathology’s historical prominence in academic and specialty medicine, in part due to technological advancements and greater consumer demand for medical procedures and their associated revenue-generating capacities. Academia is increasingly dependent upon such revenue for its educational mission that hospital clinicians can generate from a client base considering their pets members of the family.

While academic pathology is important for teaching new veterinarians and guiding appropriate therapies, we all know the plight society has chosen for many of its teachers—highly valued but under resourced and compensated. Revenue generation in pathology is now increasingly scaled to services provided with greater throughput within corporate and private entities, and found increasingly outsourced, including contract research organizations and diagnostic labs. Increased corporate concentration of veterinary diagnostics today influences choices made and investments placed.

As a consequence of this changed setting, ACVP must circumnavigate organizational tendencies to be complacent. We should station ourselves for a new phase of

September 2015

ACVPACVPAn Official Publication of The American College of Veterinary Pathologists

From the President The Secretary/Treasurer’s Corner

On the Inside:continued on page 4 continued on page 3

To continue our relevance as a

peer in modern medicine and

to ensure a more expansive

future, pathologists

will need to adopt new

skills to add to their classical

toolbox.

Page 2• MembersintheNewsPage 3• ErratumNoticePage 6• UCDavisAchievementAwards

Page 7• ExternshipReportPages 8-16• PreliminaryProgram

Pages 17-18• SilentAuctionInfo&Application9• Obituaries

ACVP Newsletter • September 2015

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ACVP Executive Offices:2424 American LaneMadison, WI 53704-3102 USA

Phone: +1-608-443-2466Fax: +1-608-443-2474E-Mail: info@acvp. orgACVP Website: http://www.acvp.org

ACVP Newsletter Editor:Kaori Sakamoto, DVM, PhD, Dipl. ACVPDepartment of PathologyCollege of Veterinary MedicineUniversity of Georgia501 D.W. Brooks AvenueAthens, GA 30602-7388Phone: +1-706-542-5844Fax: +1-706-542-5828

Members in the News

Dr. Alan RebarPhoto courtesy of Purdue University.

Dr. Alan Rebar, Senior Associate Vice President for Research, Executive Director of Discovery Park, and Professor of clinical pathology at Purdue University, has been named Vice Chancellor for Research, Innovation, and Economic Development at North Carolina State University, effective on or before September 14.

“Dr. Rebar has a successful leadership track record and has directed the tremendous growth of Discovery Park, Purdue’s hub for translational and interdisciplinary research,” Chancellor Randy Woodson said. “We are looking forward to his leadership in research, innovation, and economic development, as we continue the growth of our research enterprise and the translation of this work into economic prosperity for our state and nation.” Rebar is internationally recognized for his work in clinical laboratory medicine, with areas of expertise in comparative hematology, diagnostic cytology and toxicologic pathology.

“I am thrilled to be joining the NC State administrative team,” Rebar said. “NC State is an outstanding land-grant university with an excellent reputation for both fundamental scholarship and solution-driven research with direct societal and economic impact. It is an honor to be selected for this position.”

NC State’s research portfolio includes more than 3,450 invention disclosures, more than 850 U.S. patents, more than 400 products brought to market, more than 100 startup companies, more than 8,000 jobs created and $1.6 billion in financing. NC State’s Centennial Campus is the pre-eminent university research campus in the country, with more than 70 corporate, government or non-profit partners working alongside more than 75 university centers, institutes, laboratories and department units.

Rebar is a Diplomate of the American College of Veterinary Pathologists, a former member of the Council of the American College of Veterinary Pathologists, past-president of the American Society for Veterinary Clinical Pathology, former editor of the journal Veterinary Clinical Pathology and current editor of the Journal of the American Animal Hospital Association.

Rebar also served as dean of Purdue’s College of Veterinary Medicine from 1996 to 2005, and as associate dean for research in the college from 1989 to 1996.

He has authored or co-authored 120 refereed publications and eight textbooks, and has made nearly 300 invited lectures at workshops and conferences in the United States and around the globe. He has served as a scientific advisor to numerous federal agencies and companies.

In recognition of his achievements, Rebar received the Award of Merit from the American Animal Hospital Association in 1989, and in 1994 he received the Gaines Cycle Fido Award for outstanding contribution to small animal medicine and surgery. He also received the 2001 Waltham Award given in recognition of outstanding activities or contributions by a veterinarian that have resulted in the improvement of the well-being of companion animals in the international veterinary community.

Rebar earned his doctorate in veterinary medicine in 1973 and his PhD in veterinary pathology in 1975, both from Purdue.


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Secretary/Treasurer - continued from page 1

specialty. Some of the world’s experts in various areas will be there to present and participate. The Education Committee has created a fantastic schedule along with first-class workshops and sessions. These include sessions on biomarkers, dermatopathology, best practices for data analysis, genetically-engineered large animals, resident training, forensic pathology, skin injury, avian/exotics, flow cytometry and clonality assays, cutaneous toxicity, and medical device pathology. Pre- and post-meeting workshops include primate pathology, biomarkers, aquatic species, pathology potpourri, ocular pathology, use of pigs in biomedical research, molecular pathology, and mouse neuropathology. And, of course, we have the great interactive poster and scientific sessions, students and residents, exhibitors, accompanying guests, and the great community of our ACVP family.

The venue, the Minneapolis Convention Center in downtown Minneapolis, is also excellent. During the Council Meeting in May, we visited the Minneapolis Convention Center and saw firsthand the various rooms, exhibitor space, and amenities. We took a break at a small, craft beer lounge along an outpouching of a staircase, and enjoyed some of the beers and appetizers. As an added adventure, Comic Con Minneapolis 2015 was ongoing at that time, and we got to see a lot of costumes, many of which I didn’t recognize but found interesting.

West of the Convention Center is Loring Park, with walking paths and a lake, and a pathway across highway 12 to the Minneapolis Sculpture Garden. Just a few steps north of the Convention Center is the Nicollet Mall, which is an 11-block street area of shops, dining, hotels, and also the Mary Tyler Moore statue, where she throws her hat in the air. During my stay, I ran north to the Mississippi River by the River Front District (with the Mill City Museum and Guthrie Theater), then along the River under a few bridges to the University of Minnesota campus, where I crossed the walking bridge, along which I saw a large tree with hundreds (I think) of shoes tied together by their shoestrings and strung over branches, dangling. I plan to run to and around the Sculpture Garden in October. I also visited a trendy coffee shop “Isle Bun & Coffee” on 28th and Hennipen, where I had my best cinnamon roll of the year. The caramel rolls look good also, and the café delivers.

Minneapolis has more theater seats than any city outside New York, including a Children’s theater and several stages that are present in the Convention Center. The city also has professional sports (Vikings, [home Oct. 18], Timberwolves, Wild [hockey; away], and Twins), 60 museums, the Minneapolis Institute of Arts, the Walker Art Center, and a climate-controlled skyway system. Then, a distance away, there is the Minneapolis Zoo and the Mall of America (five minutes from the airport; it has its own zip code). Yes, it is Minnesota, but it’s October, not January. Historical temperatures are highs in the upper 50s and lows in the upper 30s.

Combined Annual Meeting | October 17–21, 2015Minneapolis Convention Center and Hyatt Regency Minneapolis Hotel

www.asvcp.orgwww.acvp.org www.toxpath.org

ACVP | ASVCP | STP

Erratum for the 2015 Newly Certified Diplomates of the American College of Veterinary Pathologists:

Veterinary Anatomic Pathology

Amanda J. DennisColumbia, SC United States

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achievement in veterinary pathology. Sustaining societal relevance tomorrow means more than continuing to do what has worked well for pathologists up to now. We have to be prepared for change commensurate with societal expectations and opportunities. There are numerous examples of failed corporations that were too slow to adapt to their changing futures. As an organization, ACVP must innovate and adjust accordingly to continue ensuring a bright future. Soundly then, ACVP has embraced a proactive contemporary agenda, including ensuring mechanisms to sustain outstanding quality and service, and the means to best position ourselves as dynamic contributors for tomorrow. This is why you are seeing ACVP consider implementing what would be some of the most sweeping changes in our organization’s history. I hope you sense the energy and discipline propelling ACVP, as it embraces updates to its many activities. This is the direct consequence of many dedicated members volunteering their talents to mold capacity for all our futures. These members are too numerous to name them all in this article sadly, which is actually a great position for our organization to be in, as the leader in veterinary and comparative pathology.

Change is not sought for the sake of change. Change does not mean we negate core foundational aspects of our responsibilities; just that it is imperative right now that we adapt to a changing province of pathology disciplinary skills and knowledge base to align with new opportunities. To continue our relevance as a peer in modern medicine and to ensure a more expansive future, pathologists will need to adopt new skills to add to their classical toolbox. All discoveries and improvements in health care in the future will involve molecular medicine. Pathology practice must embrace this.

Keys to pathology’s future will include engaging new and different clients, while contributing more proactively as members of the health care team. Pathologists today well recognize the limits encountered in attempting to expand the numbers of pathologists significantly. For one thing, we risk doing this today out of sync with current market demand. AVMA studies continue to forecast oversupply/underutilization of veterinary services at least through 2025. Not idly satisfied while awaiting reinvigoration of circumstances we once knew, we must next move toward adopting ways to work more efficiently and effectively to stimulate new directions. We must broaden our vision of what veterinary pathology is and how it fits into biomedicine and health care.

So just how is the organization proactively leading change, and how do we find and fine-tune our way? Some of the change under way is organizational mechanics, while other elements influence your professional sphere more evidently. ACVP is modernizing, while we simultaneously address trends in the field and society more broadly. ACVP’s approach is a view to a horizon. Progress evolves along varying paths, with several interrelated component activities at multiple stages of evolution, and we should avoid any tendency to see things as a single snapshot.

Some of our new and emerging developments: Please join your College in supporting your future.

ACVP Maintenance of Certification (MOC): Time-limited board certification (mandated by the AVMA) begins next year. All diplomas issued in 2016 and thereafter will be time-limited, expiring at 10 years from the first year of issuance. ACVP will be ready for this mandated change with a program to accommodate maintaining one’s certification. Participation in MOC for newly-certified diplomates is mandatory and enables one to obtain renewal certificates at 10-year intervals. Members with lifelong certificates can participate voluntarily in the program and also maintain their currently held non-expiring diplomas. Keeping current in pathology has always been a naturally accepted expectation for one’s career. The program will be administered within our new website functionality. Our new web portal for operating MOC is ACVP intellectual property contributed by Glade Weiser and MOC Development Committee members, Amanda Fales-Williams (Chair), Eric Blomme, Andrea Groene, Mark Cline, and Bob Hall. The MOC program has been edited in response to members’ comments developed through an advisory panel led by Todd Johnson, and members organized by MOC Committee chair, Amy Durham, are currently testing the portal in actual use. The program will open by year’s end.

ACVP Exams: The ACVP Phase I Examination in general pathology introduced this year is not a certifying examination, as no professional credential designation is achieved by passing it. It is a mandated test taken by candidates during training before they attain eligibility for certification, and is necessary for demonstrating a required portion of the knowledge base and experience essential for the practice of pathology and ACVP board certification. In 2016, passing the Phase I Examination in general pathology becomes one of the required credentials for subsequent eligibility to sit the ACVP Certifying Examination in either anatomic or clinical pathology, which may only occur upon completion of all requirements.

Redesign of The ACVP Phase II Certifying Examinations in Anatomic or Clinical Pathology is currently being considered. In 2014, the ACVP implemented a formalized process for examination passing point determination, and in 2015, implemented a quality assurance examination process known as equating. Articles about these examination changes have appeared in previous newsletters. Early in 2015, I participated in a site visit with the Certification Examination Board (CEB) and Examination Committee representatives to the American Board of Pathology testing center in Tampa, FL. Subsequent to this visit, steps under consideration regarding the future of our certifying examinations accelerated, due to the efforts of a CEB phase II examination redesign group, led by Dorothee Bienzle and including Mark Ackermann, Keith Harris, Glade Weiser, and Linda Berent. Redesigning the Phase II Certifying Examinations will permit refinements, including implementation of technology enhancements to modernize exam administration, and improved quality assurance measures consistent with administering standardized test practices that we have already adopted. Consideration of all such steps is extensive, and we are seeking feedback widely on concepts being considered for streamlining the certifying examinations from members and

From The President - continued from page 1

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ACVP Newsletter • September 2015From The President - continued from page 4

stakeholders. This conversation will continue as The ACVP Phase II Certifying Examination redesign topic is more broadly introduced to the membership through a special edition electronic newsletter that was delivered on September 10, 2015. This will be followed by discussions with members and other stakeholders during two, to-be-announced, online webinars on September 17 and 24, 2015. A town hall meeting on the Phase II Certifying Examination redesign concept is planned for the Minneapolis annual scientific meeting at 1:30 p.m., Tuesday, October 20, 2015. We look forward to your input on continuing ACVP’s renown credentialing of veterinary pathologists as the College updates the process.

Credentialing Candidates for the ACVP Examinations. As a component of our comprehensive updates to ACVP’s credentialing of pathologists and implementing standardized testing industry best practices, Council tasked the ACVP Credentialing Committee with reviewing our procedures for credentialing candidates for the exams. The committee considered similar veterinary specialties’ practices for credentialing their candidates for certifying examinations and how ACVP accomplishes current procedures relative to bylaws and AVMA expectations. This report, led by Todd Johnson, has been produced and is now being presented for review by Council. This process is anticipated to result in modernization of some of ACVP‘s policies to clarify and standardize various procedures for candidates.

ACVP Finances. At the outset of my term as president in November 2014, ACVP finances were uppermost in my mind. The College is healthy financially, however due to the difficult economic climate in the US since 2007, the College has been experiencing a prolonged pattern of deficit spending. This year, ACVP did make a gentle return to the black; however, ACVP short-term operating reserve assets for supporting our annual operating budget funds are depleted. Now we have to reinvigorate these reserve savings accounts built up over so many years through the generosity of our members and other benefactors, in order to position the ACVP for future opportunities.

In response to today’s financial realities, Council is chartering a new standing Finance Committee that will be empaneled to help keep fiscal health at the forefront of how we do business. It is one committee almost every nonprofit organization finds difficult to function without. While financial issues can be basically mundane, we will be looking to some very dedicated members to serve in this vital capacity touching all aspects of the College. The Finance Committee will increase comprehension of the budget, as well as facilitate careful management and consideration of programs and new ideas, in keeping with our aspirational goals and pocketbook. Unfortunately, every good idea cannot be automatically adopted. Programs must undergo periodic evaluation for their effectiveness and continued relevance to our mission. Change is never easy, and change involving budget reductions can be particularly difficult to implement. ACVP budget realities mean that members must anticipate that some cuts to expenses are forthcoming, as are some changes to generate new revenue. We always love your donations, particularly with the flexibility to deal with life’s little emergencies.

ACVP Vision: One brand new idea adopted in 2015 aims to address ACVP’s vision statement: “To be an innovative and integral contributor to global health solutions by understanding disease.” Working with experienced ACVP members and relevant allied societies knowledgeable about overseas development projects, we launched the new ACVP Global Health Initiative to collaborate, develop, and discover. I introduced this initiative to you in the June 2015 newsletter. Since then, ACVP has helped to organize and deliver its inaugural workshop on pathology diagnostics in Uganda in collaboration with Veterinarians Without Borders, Farmer to Farmer (USAID), and Heifer International. Sarah Corner delivered an ACVP curriculum for pathologists and veterinarians that she co-developed with Tanja Zabka and Corrie Brown. This nascent ACVP Global Health enterprise will need cultivation by our members. An ACVP organizing committee is being developed to advance the vision and to provide a conduit to help members collaborate and seek support for this service avenue. In the form of a Global Health Network, this ACVP initiative has immense potential for the future contributions of our College and its members in achieving our vision. In addition to supporting food security and public health in developing countries, this ACVP Global Health Initiative can furthermore lead to our contributing to the discovery and control of potential emergent diseases, in collaboration with our colleagues in other countries in Africa and elsewhere.

Future Directions. 2015 also marks the opening of a needed dialog on future practice and a renewed vision for pathology. In our traditional town hall meeting in Minneapolis on Sunday, October 18, 2015, the ACVP/STP Coalition for Veterinary Pathology Fellows is organizing a discussion, led by John Sagartz, on future practice directions and needed skill sets. This town hall will precede and inform strategic discussion in a meeting between STP and ACVP officers, and also foment an ACVP strategy workshop aimed at advising ACVP Council and past Presidents on preparations for conceiving a 2017-2022 ACVP strategic plan, as it nears reconsideration.

ACVP.org. 2015 yields another revision to our acvp.org website. This project, led initially by Aaron Sargeant and now Jessica Grieves, introduces a new platform with new features. Members have new ways of interacting, and we have direct access to updating key information to keep it current. It continues to be in development stages, and it will function, obtain more content, be more illustrated, and also become more outward facing, to address those interested in disease and pathology as non-pathologists who want to get to know us better.

I look forward to seeing you online and in Minneapolis. The annual ACVP scientific meeting, planned by Kelli Boyd and the Education Committee, will be an outstanding combined meeting developed with the ASVCP and the STP, in its first such manifestation. The whole exciting business there will be about our futures and the positive future of veterinary pathology.

Corrie BrownPracticing One Health for All

DVM ’81, PhD ’86, Dipl. American College of Vet-erinary Pathologists (ACVP), Josiah Meigs Distin-guished Teaching Professor, College of Veterinary Medicine, University of Georgia

Brown is honored for her ceaseless dedication to excellence in teaching, veterinary science, and control of infectious disease for the health of all.

As a pathologist, Brown has worked nationally and internationally for more than 25 years, building animal health infrastructure and diagnostics. She specifically studies emerging diseases, pathogenesis of disease in food-producing animals, and diagnostic infrastructure in developing countries.

Her work in international food security and bioterrorism is marked by high recognition from the Departments of State, Homeland Security, Agriculture, and Defense, and other intergovernmental groups, such as the United Nations Food and Agriculture Organization, as well as the World Health Organization and World Animal Health Organization.

Brown joined the University of Georgia’s (UGA) College of Veterinary Medicine in 1996. In 2004, she received the school’s highest teaching award, the Josiah Meigs Distinguished Teaching Professorship and, for 2009-2010, was named a UGA Senior Teaching Fellow.

Her work in more than 30 countries includes conducting workshops on basic field necropsy and diagnostic techniques. She also has served on national and international expert panels about animal health and has received numerous awards, including the XIIth International Veterinary Congress Prize from the American Veterinary Medical Association (AVMA) in 2013. The annual prize recognizes outstanding global service by a member of the AVMA, which, with more than 84,000 members, is one of the oldest and largest veterinary medical organizations in the world.

Prior to her current position, Brown was head of the pathology section with the U.S. Department of Agriculture at Plum Island, where she specialized in the diagnosis and pathogenesis of trans-boundary animal diseases. She was also an assistant professor of pathology at Louisiana State University.

Brown is regarded by her colleagues as a dedicated veterinarian, pathologist, humanitarian, and educator who embodies in her work and her life a passion for the veterinary profession and for those less fortunate in the world.

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University of California Davis 2015 Alumni Achievement AwardsMay 22, 2015

Four illustrious alumni from UC Davis School of Veterinary Medicine have been honored this week with the 2015 Alumni Achievement Award.

The Alumni Achievement Award recognizes individuals who have made personal and professional contributions to veterinary science, veterinary practice, or advanced human welfare. The awards are officially presented at the school’s commencement ceremony in June. Honorees may be graduates of the Doctor of Veterinary Medicine, Master of Preventive Veterinary Medicine, MS, or PhD programs, or veterinarians who have completed an internship or residency at the school.

This year’s awardees are: Corrie Brown, DVM ’81, PhD ’86*Tim Carpenter, MS ’74, MS ’78, PhD ’79Jack R. Harkema, MS ’77, DVM ’80, PhD ’85*Donald Janssen, DVM ’78, DACZM *denotes an ACVP Member

Jack R. HarkemaUnderstanding Health Effects of Air Pollutants

MS ’77, DVM ’80, PhD ’85, Dipl. American College of Veterinary Pathologists (ACVP), Distinguished Professor of Pathobiology, Michigan State University (MSU)

Harkema is honored for his exceptional leadership, commitment to teaching, and

outstanding scientific accomplishments in veterinary and toxicologic pathology.

As a biomedical researcher, Harkema focuses his studies on understanding the pathobiology and toxicology underlying the health effects of environmental and occupational air pollutants. Much of his recent work deals with developing animal models of human cardiopulmonary and metabolic disease (e.g., asthma, cardiometabolic syndrome) used to investigate how acute or chronic disease may affect an individual’s susceptibility to toxicant-induced injury and subsequent repair.

After completing an NIH-sponsored residency/research training program in comparative pathology and toxicology at UC Davis following his PhD, Harkema joined the scientific staff at the Lovelace Inhalation Toxicology Research Institute in Albuquerque, NM, in 1985 as an experimental and toxicologic pathologist, and later became the institute’s project manager for pathogenesis research.

In 1994, Harkema joined the faculty of the Department of Pathobiology and Diagnostic Investigation in the College of Veterinary Medicine at MSU, where he received his DVM. In 2011, he became the Director of the Great Lakes Air Research Center for Integrative Environmental Research (GLACIER), one of four EPA-funded Clean Air Research Centers in the nation. Harkema has co-authored more than 200 peer-reviewed scientific publications and has served on numerous scientific advisory committees, including those for the National Institutes of Health, Environmental Protection Agency, and National Academy of Sciences.

In addition to training graduate students, residents, and postdoctoral fellows in biomedical research, he also moderates courses in advanced general pathology, integrative toxicology, and pulmonary pathobiology. Harkema is a member of the Society of Toxicologic Pathologists, the Society of Toxicology, and the ATS. His work has been recognized with numerous honors, including the 2001 Pfizer Award for Research Excellence and the 2006 Distinguished Faculty Award, both given to him from the College of Veterinary Medicine at MSU.

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ACVP Extern Scholarship Reports

Joanna RybickaUniversity of Calgary

This summer, I had an opportunity to complete two externships owing to the generous financial support provided through the ACVP Externship Scholarship. My first externship took place at the Western College of Veterinary Medicine (WCVM) at the University of Saskatchewan, and I was very privileged to have received a matching scholarship from WCVM to support my externship. During my time in Saskatoon, I had the privilege of working with Dr. Elemir Simko on elucidating putative biomarkers in plasma and serum of cattle for antemortem diagnosis of sulphur-induced polioencephalomalacia.

During my 10-week externship, I was able to not only acquire new skills in proteomics but also identify 4 distinct proteins, which were differentially expressed in the plasma and serum of cattle affected with spontaneously occurring, sulphur-induced polio, when compared to subclinically-affected animals and controls. We are currently working with our collaborators at the College of Medicine, University of Saskatchewan, on identifying these proteins through mass spectrometry and will be presenting our findings at the upcoming ACVP meeting this fall. Through this experience, I have gained a substantial insight into the pathophysiology of this devastating and poorly understood disease but also had the opportunity to attend the C.L. Davis Foundation Descriptive Pathology course, and the XVII International Symposium of the World Association of Veterinary Laboratory Diagnosticians (WVALD) in Saskatoon.

Following my externship at WCVM, I had the immense privilege to complete an externship at the Animal Health Laboratory in Abbotsford, British Columbia, under the supervision of Drs. Stephen Raverty and Ann Britton. During this externship, I gained a considerable amount of experience in histopathology, while improving my skills in necropsy. During my time in Abbotsford, I had the chance to see many unusual cases, especially in wildlife and exotic species, such as an Ibex, Spectacled Caimans, and Harbour Seals, among others. Additionally, I have been able to participate in several forensic necropsies that were submitted through provincial SPCA authorities. This allowed me to put into practice the knowledge I gained from attending the WVALD meeting in Saskatoon and gain further insight into the complexity and challenges of such investigations.

In summary, I feel very grateful for the opportunity to experience so many different aspects of veterinary pathology, none of which would have been possible without the funds available through the ACVP Externship Scholarship. All of these experiences have not only equipped me with a broad range of skills that will be valuable throughout the reminder of my DVM programme, but also gave me invaluable networking opportunities and solidified my desire to pursue an anatomic pathology residency following graduation.

ACVP congratulates the American Society for Veterinary Clinical Pathology

on its 50th anniversary.

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American College of Veterinary Pathologists American Society for Veterinary Clinical Pathology

ACVP | ASVCP | STPMINNEAPOLIS CONVENTION CENTER | MINNEAPOLIS, MNOCTOBER 17-21 COMBINED ANNUAL MEETING

Preliminary Program

2015

*ACVP Diplomate

8:00 a.m.-5:00 p.m. ACVP Primate Pathology Pre-Meeting Workshop (available for an extra fee)Non-Human Primate Genetics and Geography: Impact on Study Design, Interpretation, and Results

8:00 a.m.-8:15 a.m. Welcome and Program OverviewVito Sasseville, DVM, PhD*

8:15 a.m.-9:00 a.m. DNA-based Ancestry Determination of Rhesus (Macaca mulatta) and Cynomolgus Macaques (M. fascicularis)

Sree Kanthaswamy, BS(HONS), MPhil, PhD

9:00 a.m.-11:15 a.m. NHP Genetic Background Impact on Study Design, Interpretation, and Results: Industrial and Academic Perspective

9:00 a.m.-9:30 a.mCynomolgus Monkey Origin: Clinical Pathology and Immunotoxicology Considerations

Nancy E. Everds, DVM*

9:30 a.m.-10:00 a.m.Retrospective Program Analysis

Karyn Colman, BVetMed, MRCVS

10:00 a.m.-10:15 a.mRefreshment Break10:15 a.m.-10:45 a.m.Comparison of Background Histopatholgy Findings in Asian and Mauritius Cynomolgus Macaques

Jagannatha Mysore, MVSc, PhD*

10:45 a.m.-11:15 a.m.Macaque Species Susceptibility to Simian Immunodeficiency Virus

Joseph Mankowski, DVM, PhD*

11:15 a.m.-12:00 noon Background Infections and Molecular Detection of Etiologic Agents

Keith Mansfield, DVM*12:00 noon-1:00 p.m. Lunch Break (on your own)

1:00 p.m.-3:00 p.m. Case Presentations 3:00 p.m.-3:30 p.m. Refreshment Break3:30 p.m.-5:30 p.m. Case Presentations

7:00 a.m.-7:00 p.m. Registration8:00 a.m.-5:00 p.m. Combined ASVCP, STP, CPIG Pre-Meeting Workshop

(available at an additional fee)Application of New Renal and Hemostatic Bio-markers in Veterinary Medicine and Preclinical Safety: What Can We Learn from Each Other?

8:00 a.m.-8:10 a.m. WelcomeModerators: Kirstin Barnhart, DVM, PhD*William J. Reagan, DVM, PhD*

Morning Session: Renal Biomarkers8:10 a.m.-9:00 a.m. Qualification of New Translational Kidney Safety

Biomarkers for Drug DevelopmentWarren Glaab, PhD

9:00 a.m.-9:40 a.m. Recent Developments in Canine Urinary BiomarkersMary Nabity, DVM, PhD*

9:40 a.m. -10:10 a.m. Assessing Immune Complex Glomerulopathy with Morphology and Biomarkers in Non-human Primate Kidneys During Preclinical Safety Testing of Biologics

Tom P. Brown, DVM, MS, PhD*10:10 a.m. -10:30 a.m. Refreshment Break

10:30 a.m. -11:00 a.m. Early Detection of AKI and CKD in Dogs and the Role of IRIS Guidelines

Mary Nabity, DVM, PhD*

11:00 a.m. -11:50 a.m. An Integrated Approach to Assessing Kidney Injury

Rachel Cianciolo, DVM, PhD*11:50 a.m. -1:00 p.m. Lunch (boxed lunches to be provided)Afternoon Session: Hemostasis Biomarkers

1:00 p.m.-1:50 p.m. Hemostasis Gaps in Preclinical and Clinical Studies-Biomarkers for Procoagulant States

Eric Schultze, DVM, PhD*

1:50 p.m.-2:40 p.m. Comparative Hemostasis Testing: Beyond APTT and PT

Marjory Brooks, DVM, DACVIM2:40 p.m.-3:00 p.m. Refreshment Break

3:00 p.m.-3:20 p.m. Monitoring Hypercoagulability in Pro-Thrombotic Conditions and Hypocoagulability in Hemophilic Models, in Non-Human Primates

Florence Poitout, DVM, DECVCP*

3:20 p.m.-4:10 p.m. Platelet Function Testing in Non Human PrimatesKelly Metcalf Pate, DVM, PhD, DACLAM

4:10 p.m.-4:40 p.m. Platelet Isolation Techniques in Laboratory Animals and Platelet Function Testing in Dogs

Adam Aulbach, DVM, PhD*

4:40 p.m. -5:00 p.m. Buccal Mucosal Bleeding Time: Application in Pre-clinical Safety

Kirstin Barnhart DVM PhD*

Saturday, October 17

Friday, October 16 Saturday (continued)

Registrants will receive on-line access to all case presentation materials (including clinical history and scanned slide images) prior to the meeting.

6:00 p.m.-8:00 p.m. Registration

1 of 9

As of September 16, 2015. For more current program information, check www.acvp.org, Meetings Information.

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Preliminary Program

2015

*ACVP Diplomate

Program subject to changeSociety of Toxicologic Pathology

8:00 a.m.-5:00 p.m. C.L. Davis Foundation Pre-Meeting WorkshopThe Life (and Death) Aquatic

Jeffrey C. Wolf, DVM*Judy St. Leger, DVM*

This full-day course will cover topics from normal anatomy and histology to classic and important pathology in aquatic species. Species covered will include fish, amphibians, reptiles, birds, and marine mammals. The tag-team faculty will present material in a step-wise manner so that pathologists will be both engaged and educated. The workshop will focus on the identification of both normal anatomy and common diseases of these species including gross and histologic appearance, salient diagnostic features, and differential diagnosis. This exciting course should be of interest to both clinical and anatomic veterinary pathologists, pathology residents, and diagnosticians working with animals.

9:00 a.m.-4:30 p.m. NTP Satellite Symposium Pathology Potpourri

Session Chair: Susan A. Elmore, MS, DVM, DABT, FIATP*

9:00 a.m.-9:10 a.m. Welcome and Introductory RemarksSusan A. Elmore, MS, DVM, DABT, FIATP*

9:10 a.m.-9:30 a.m. It’s Not a TumorDavid E. Malarkey DVM, PhD, FIATP*

9:30 a.m.-10:00 a.m. Cardiomyopathy ShuffleRick Hailey, DVM

10:00 a.m.-10:30 a.m. Queries from the ZooPatricia A. Pesavento DVM, PhD*

10:30 a.m.-11:00 a.m. Refreshment Break11:00 a.m.-11:30 a.m. An Exigent Pancreatic Tumor?

Ramesh C. Kovi, BVSc & AH, MVSc, PhD*

11:30 a.m.-12:00 noon Intracranial Conundrums IJames P. Morrison DVM*

12:00 noon-1:30 p.m. Lunch (on your own)1:30 p.m.-1:50 p.m. Mammary Gland Development: The “Whole” Story

Erin Quist, DVM, MS*

1:50 p.m.-2:10 p.m. Canine and Rodent Pulmonary Pathology: Are They the Same or Different?

Kathleen A. Szabo, DVM, MS*

2:10 p.m.-2:30 p.m. Imprints, Smears and Preps - Oh My!Jennifer Neel DVM*

2:30 p.m.-3:00 p.m. Neuropathology Texas-Style Brian F. Porter DVM*

3:00 p.m.-3:30 p.m. Refreshment Break3:30 p.m.-3:50 p.m. Intracranial Conundrums II

James P. Morrison DVM*

3:50 p.m.-4:30 p.m. Challenging Cases from the Special Senses INHAND OWG

Cindy A. Farman DVM PhD*Leandro Teixeira DVM MSc*

8:00 a.m.-12:00 noon STP Pre-Meeting CE Course 1All Eyes Focused on Ocular Toxicology and Pathology (available at an additional fee)

Session Co-Chairs: Brian J. Christian, PhD, DABTMargarita M. Gruebbel, DVM, PhD*

The eye is often a target organ in toxicology studies. In order to determine the toxicological significance of effects in the eye, it is important to understand the basic structure and function of ocular tissues. Designing protocols for ocular toxicology studies also requires knowledge of species differences among the common testing laboratories as well as current methods for evaluation of ocular structures and functions. This session includes detailed reviews of anterior and posterior segments of the eye of common laboratory species; different tools used to determine treatment-related effects in ocular structures; and spontaneous and induced changes observed in each segment of the eye.

Comparative Anatomy and Histology of the Eye of Laboratory Animals

Margarita M. Gruebbel, DVM, PhD*

Evaluation of the Cornea and Lens Robert J. Munger, DVM, DACVO

Evaluation of the Anterior and Posterior Chambers and Iridocorneal Angle

Leandro Teixeira, DVM, MSc*

Examination and Evaluation of the Posterior Segment—Retina

Steven D. Sorden, DVM, PhD*12:00 noon-7:00 p.m. Speaker Ready Room

1:30 p.m.-5:00 p.m. STP Pre-Meeting CE Course 2The Use of Pigs in Biomedical Research (available at an additional fee)

Session Co-Chairs: Lydia Andrews-Jones, DVM, PhD*Kristie Mozzachio, DVM*

Swine are increasingly being used in biomedical research, both in toxicologic pathology and in medical devices work, including as possible organ donors for humans. This course will review the various strains of pigs used for biomedical research, their unique anatomy, clinical pathology, and background diseases and lesions. In addition to general toxicology, the use of pigs in dermato-logic, ocular, and device work will be reviewed by subject matter experts.

Pig Strains Used in Biomedical Research: Sources, Origins, and Colony Health Management

Guy Bouchard, DVM, MS, DACT

Pig Anatomic and Clinical Pathology: Background and Unique Considerations

Kristie Mozzachio, DVM*

Sexual Maturity of Minipigs Paul Howroyd, MA, VETMB, MRCVS, FRCPath

Saturday (continued) Saturday (continued)

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2015

*ACVP Diplomate

Pigs in General Toxicology—The European Perspective

Alys Bradley, BSc, BVSc, MAnimSc, DipRCPath, FRIPH, MRCVS, FRCPath, FIATP

The Minipig as a Translationally Relevant Model of Human Cardiovascular Disease

James Turk, AB, DVM, PhD*

The Swine as a Model in Experimental and Translational Medicine

Alain Stricker-Krongrad, PhD, MSc

So... How DO You Work with Pigs?Kristie Mozzachio, DVM*

3:00 p.m.-8:30 p.m. Career Center5:15 p.m.-6:15 p.m. Job Searching 2.0

Using Social Media and Connections to Find Your Right Job

Heather Jury, IDEXX Laboratories

This interactive session is designed to help attendees get an insider view of job seeking, networking, and strategies to identify the right position and create their career path. Attendees at this session will have the opportunity to learn about “Job Searching 2.0”, ask questions and hear candid advice. This program will review definitions of new media/social media, and discuss: what is social media now? How has social media changed the landscape of job searching and networking? Who is using social media to find employees? How do recruiters see you? Why is networking and connecting a critical part of job searching today?

There will be in-depth discussion about the social networking “Big Three”: Facebook, Twitter and LinkedIn, plus a review of other sites including Insta-gram, Indeed, Glassdoor and more. This program will include a discussion about social strategies, privacy settings, etiquette in this new era, as well as tips and “hacks” for effective job seeking. Participants will leave with actions to take now and later to successfully identify their career path.

5:30 p.m.-7:00 p.m. Trainee Mixer

6:00 p.m.-8:00 p.m. ASVCP Teaching Clinical PathologySession Chair: Carolyn Grimes, DVM*

7:00 p.m.-8:30 p.m. Opening Reception, Exhibits, Silent Auction

7:00 a.m.-5:00 p.m. Registration7:00 a.m.-6:00 p.m. Speaker Ready Room

8:00 a.m.-12:00 noon ASVCP Education SymposiumBiomarkers in Veterinary Clinical Pathology

Session Chair: Laura Snyder, DVM*

8:00 a.m.-8:50 a.m. Bridging Man and Preclinical Species: The Rain-bow of Non-Vasoactive Vasculitidies

Igor Mikaelian, DVM*

8:50 a.m.-9:40 a.m. SDMA as a New Serum Marker of Kidney FunctionMary Nabity, DVM, PhD*

9:40 a.m.-10:10 a.m. Refreshment Break10:10 a.m.-11:00 a.m. Biomarkers for Lymphoproliferative Disorders

Anne Avery, VMD, PhD

11:00 a.m.-11:50 a.m. Diagnosis of Systemic Mycoses By Use of Biomarkers Lawrence J. Wheat, MD

11:50 a.m.-12:00 noon Questions and Discussion

8:00 a.m.-12:00 noon Concurrent Session I Diagnostic Veterinary Dermatopathology

Session Chairs: Pauline M. Rakich, DVM, PhDJoanne Mansell, DVM, MRCVS*

8:00 a.m.-8:10 a.m. Welcome

8:10 a.m.-9:00 a.m. Interface Dermatitis Verena K. Affolter, DrMedVet, PhD, DECVP

9:00 a.m.-9:50 a.m. Interface Dermatitis: The Immunologic and Clini-cal Perspective

Valerie A. Fadok, DVM, PhD, DACVD9:50 a.m.-10:20 a.m. Refreshment Break

10:20 a.m.-11:10 a.m. The Hair Follicle and the Yet Unsolved Mystery of Non-Inflammatory Alopecia

Monika Welle, Prof. DrMedVet, DECVP

11:10 a.m.-12:00 noon Diagnostic Dermatopathology for General Veteri-nary Pathologists

Elizabeth A. Mauldin, DVM, DACVD*

8:00 a.m.-12:00 noon Joint ACVP, ASVCP, and STP Career Development SessionVisualizing Pathology Data

Session Chair: Nancy E. Everds, DVM*Danielle L. Brown, DVM, MS*

8:00 a.m.-8:10 a.m. Opening Remarks

8:10 a.m.-8:50 a.m. Tips and Tricks for Visualizing Numerical DataNancy E. Everds, DVM*

8:50 a.m.-9:30 a.m. Pitfalls and Unintended Biases in Image AnalysisMichael C. Boyle, DVM, PhD, DABT*

9:30 a.m.-10:10 a.m. Integration of Omics Data With Pathology Data: Omics as a Tool for the Investigative Pathologist

Mark J. Hoenerhoff, DVM, PhD*10:10 a.m.-10:40 a.m. Refreshment Break

10:40 a.m.-11:20 a.m. Principles for Semi-Quantitative Scoring of TissuesDavid K. Meyerholz, DVM, PhD*

11:20 a.m.-12:00 noon Approaches, Pitfalls, and Best Practices for Mining Large Datasets

Elizabeth Lund, DVM, MPH, PhD

Saturday (continued) Sunday, October 18

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*ACVP Diplomate


8:00 a.m.-12:00 noon STP and Industrial and Toxicologic Pathology Focused Scientific Session

Session Chair: Daniela Ennulat DVM, PhD*

Invited Speakers

Methodological Advancements in the Mammary Gland: New Insights for Detecting Mammary Carcinogenesis

Suzanne E. Fenton, PhD, MS

Second Skin: From Marrow to MatrixTBA

8:00 a.m.-12:00 noon Natural Disease Focused Scientific Session ISession Chair: Andrew D. Miller, DVM*

Invited Speakers:

Pathology of Adverse Reactions to VaccinesDonal O’Toole, MVB, PhD, MRCVS, DECVP, FRCPath

The Structural and Molecular Pathology, Chemistry and Current Diagnostic Techniques of Toxic Plant Induced Disease

Bryan Stegelmeier, DVM, PhD*8:00 a.m.-5:00 p.m. Student and Guest Hospitality Room9:00 a.m.-5:00 p.m. Career Center9:30 a.m.-4:30 p.m. Exhibits and Silent Auction

9:30 a.m.-4:30 p.m. Focused Scientific Poster Session and ACVP Veterinary Student Posters

9:50 a.m.-10:40 a.m. Refreshment Break12:00 noon-1:30 p.m. Veterinary Pathology Resident/Trainee Luncheon

12:00 noon-1:30 p.m. Lunch Break (on your own)12:15 p.m.-1:15 p.m. Emerging Disease Focus Seminar: Corona Virus

Session Chair: Francisco A. Uzal, DVM, MSc, PhD*

12.15 p.m.-12.45 p.m. Emergence of Porcine Enteric Coronaviruses in North America: Differential Features and Diagnostic Trends

Eric R. Burrough, DVM, PhD

12.45 p.m.-1:15 p.m. Pathogenesis and Histopathology of Porcine Epidemic Diarrhea Virus (PEDV) and Porcine Delta Coronavirus (PDCV) in Swine

Jeff Hayes, DVM, MSc

12:00 noon-4:00 p.m. Veterinary Laboratory Professionals Session ISession Chair: Lynne Shanahan, MT, ASCP

12:00 noon-12:30 p.m. Multi-Generational Employees in the WorkplaceLynne Shanahan, MT, ASCP

12:30 p.m.-1:30 p.m. Advances in Veterinary Diagnostic and Comparative Hemostatic Testing

Marjory Brooks, DVM

1:30 p.m.-2:30 p.m. Establishing Reference IntervalsKristen R. Friedrichs, DVM*

2:30 p.m.-3:00 p.m. Refreshment Break3:00 p.m.-4:00 p.m. Sample Handling and Sources of Pre-Analytical

Variation in Laboratory AnimalsKirstin Barnhart, DVM, PhD*

1:30 p.m.-5:00 p.m. STP Focused Topic Session 1 Functional Anatomy and Physiology of Skin

Session Co-Chairs: Kelly Diegel, DVM, PhD*Aaron Sargeant, DVM, PhD*

This session will provide an overview of skin immunology and comparative and functional anatomy with emphasis on aspects important to toxicologic assessment. The pros and cons of different species will be discussed, including the use of hairless rodent models and models of human disease being used in discovery work to screen compounds for efficacy endpoints. Pitfalls and concerns of study design, especially with regards to rodent versus pig, will be covered. Finally, formulation and pharmacokinetic endpoints will be discussed, including the challenges of delivering a drug to a specific component of the skin, and issues surrounding 1) developing a formulation that will target a specific area, 2) measuring concentrations in different areas without cross contamination, and 3) appropriate endpoints for high throughput screening of compounds in vitro and how these endpoints translate in vivo.

1:30 p.m.-2:15 p.m. Functional Anatomy and Differences Between Commonly Used Animal Models, Including the Minipig

Lydia Andrews-Jones, DVM, PhD*

2:15 p.m.-3:05 p.m. Dermal Drug Delivery and PKJon Lenn, MS, PhD

3:05 p.m.-3:35 p.m. Refreshment Break3:35 p.m.-4:25 p.m. Skin Immunology and Animal Models

Suzanne Kanaly, DVM, PhD*

4:25 p.m.-5:00 p.m. Student Presentations

1:30 p.m.-4:30 p.m. Clinical Pathology Focused Scientific Session ISession Chair: Shelley Burton, DVM, MSc*

Invited Speaker

1:30 p.m.-2:30 p.m. Urinalysis – Getting Specific About Specific Gravity and Other Important Feature

Jody Lulich, DVM, PhD, DACVIM

1:30 p.m.-5:00 p.m. Diagnostic Pathology Focused Scientific Session ISession Chair: Stephen Raverty, DVM, PhD*

1:30 p.m.-5:00 p.m. Experimental Disease Focused Scientific Session ISession Chair: Sébastien Monette, DMV, MVSc*

Invited Speakers

1:30 p.m. A Pig Model of Renovascular Disease: Development and Evaluation

Lilach Lerman, MD, PhD

3:30 p.m. Comparative Biology of Breast Cancer: Lessons from Human and Nonhuman Primates, Rodents, and Other Species

J. Mark Cline, DVM, PhD*

Sunday (continued) Sunday (continued)

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*ACVP Diplomate

7:00 a.m.-6:00 p.m. Speaker Ready Room7:30 a.m.-1:00 p.m. Registration

8:00 a.m.-12:00 noon ACVP / ASVCP / STP Combined Plenary SessionBiomarkers

Session Chairs: Robert Dunstan, DVM, MS*Elizabeth Howerth, DVM, PhD*Anne Provencher DVM, MSc, DECVCP, FIATP*

For over a decade, the pursuit of biomarkers to diagnose and prognose disease and more impor-tantly, to predict which patients will respond to targeted therapies has been a major goal of both FDA and the pharmaceutical industry. However, only a handful of biomarkers have been approved by the Agency. In this session, there will be a discussion of what biomarkers are, the types of biomarkers that are currently being developed and what it takes to validate them for regulatory approval.

8:00 a.m.-8:50 a.m. Biomarkers: You May Remember Them As …Michael Bleavins, PhD, DABT

8:50 a.m.-9:40 a.m. Fluid-Based BiomarkersDana Walker, DVM, MS, PhD*

9:40 a.m.-10:10 a.m. Refreshment Break10:10 a.m.-11:00 a.m. Translational, Tomographic Imaging Biomarkers

Jack Hoppin, PhD

11:00 a.m.-11:50 a.m. Considerations for the Successful Development of New Biomarkers

Daniela Ennulat, DVM, PhD*


8:00 a.m.-12:00 noon ASVCP Veterinary Laboratory Professionals Session IISession Chair: Lynne Shanahan, MT, ASCP

8:00 a.m.-8:30 a.m. Multi-Generational Employees in the WorkplaceLynne Shanahan, MT, ASCP

8:30 a.m.-9:30 a.m. Comparative Hematology of Laboratory AnimalsKirstin Barnhart, DVM, PhD*

9:30 a.m.-10:00 a.m. Refreshment Break10:00 a.m.-11:00 a.m. Routine Clinical Chemistry, Urinalysis and Coagula-

tion Testing in Laboratory AnimalsKirstin Barnhart, DVM, PhD*

11:00 a.m.-12:00 noon Specialized Biomarkers in Laboratory AnimalsKirstin Barnhart, DVM, PhD*

8:00 a.m.-5:00 p.m. Student and Guest Hospitality Room9:00 a.m.-5:00 p.m. Career Center

9:30 a.m.-1:00 p.m. Exhibits and Silent Auction


12:15 p.m.-2:00 p.m. Latin Comparative Pathology Group Presents

1:30 p.m.-3:30 p.m. ASVCP-STP Case Discussion SessionSession Chair: Tracy Stokol, DVM, PhD*

1:30 p.m.-4:30 p.m. Community Service Project (see the registration form for more details)

1:45 p.m.-3:00 p.m. Meet the Pathologists: A Discussion of Careers in Pathology

3:00 p.m.-5:00 p.m. Veterinary Student and Resident Forum

5:15 p.m.-7:45 p.m. ASVCP Reception (all members welcome)

7:00 p.m.-9:00 p.m. Mystery Slide Review and Neuropathology Case Presentations

Session Chair: Jey Koehler, DVM, PhD*

1:30 p.m.-5:00 p.m. Natural Disease Focused Scientific Session IISession Chair: Andrew D. Miller DVM*

Invited Speaker:

Diagnostic Approach to Spontaneous Neuropathic Lysosomal Storage Diseases of Dogs and Cats

Carlo Cantile, DVM, PhD

3:00 p.m.-3:30 p.m. Refreshment Break

4:30 p.m.-6:00 p.m. ASVCP Business Meeting

5:15 p.m.-6:00 p.m. ACVP Business Meeting

6:15 p.m.-7:30 p.m. Combined ACVP and STP Town Hall Meeting

7:30 p.m.-9:30 p.m. ACVP-STP Mystery Slide Review Session Skin

Session Chair: Daniel R. Rissi, DVM, PhD*

Panelists:Dimitry M. Danilenko, DVM, PhD*Kelly Diegel, DVM, PhD*Robert W. Dunstan, DVM, MS*Joanne Mansell, DVM, MS, DACVP, MRCVS *Elizabeth A. Mauldin, DVM, DACVD*Kim Newkirk, DVM, PhD*

Sunday (continued) Monday (continued)

Monday, October 19

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Preliminary Program

2015

*ACVP Diplomate


9:40 a.m.-10:15 a.m. Refreshment Break10:15 a.m.-11:05 a.m. Cystic Fibrosis-Related Diabetes in Ferrets

Katherine Gibson-Corley, DVM, PhD*

11:05 a.m.-11:55 a.m. Origins of CF Lung Disease: Insights from a Pig Model

David K. Meyerholz, DVM, PhD*


8:00 a.m.-12:00 noon STP Focused Topic Session 2 Pathology and Mechanisms of Skin Injury

Session Co-Chairs: Dimitry Danilenko, DVM, PhD*Sebastian Brennan, DVM, MVSc*

The skin, like other organ systems, has a relatively limited range of responses to injury regardless of the specific mechanism underlying the insult. Despite this, there is still a great deal that can be ascertained from the different morphologic, physiologic, and molecular alterations that arise in response to injury. One of the skin’s primary functions is to serve as a physical and physiologic protective barrier against injury from the external environment in order to prevent the loss of water and solutes from the body. When the skin is exposed to irritants that disrupt this barrier, it mounts an inflammatory and proliferative response in an effort to restore these essential functions. The epidermis, particularly epidermal keratinocytes and dendritic cells, are central to the initiation of the skin’s response, triggering an immunologic cascade tailored to cope with a wide range of injurious stimuli and leading to the stereotypic morphologic responses that we encounter as pathologists.

This session will cover the pathology and mechanisms of cutaneous injury, beginning with an overview of our current understanding of immune-mediated mechanisms, both the adap-tive and innate that underlie the pathogenesis of cutaneous injury. Following this introduction, we will address specific cutaneous hypersensitivity models in the nonhuman primate, and we will look at mech-anisms and models for the evaluation of cutaneous phototoxicity. The final presentation will provide an overview of our current understanding of cutaneous carcinogenesis as it pertains to the evaluation of compounds with carcinogenic potential.

8:00 a.m.-12:00 noon Clinical Pathology Focused Scientific Session IISession Chair: Shelley Burton, DVM, MSc*

Invited Speaker

10:30 a.m.-11:30 a.m. Garbage in, Garbage out: Improving Oncology Care Through Collaboration

Michael Henson, DVM, PhD, DACVIM

8:00 a.m.-12:00 noon Education Focused Scientific Session Resident Training

Session Chair: Linden Craig, DVM, PhD*

8:00 a.m.-8:15 a.m. Introductions and AcknowledgementsLinden Craig, DVM, PhD*

8:15 a.m.-8:30 a.m. Combined PhD/Residency ProgramsKrista LaPerle, DVM, PhD*

8:30 a.m.-8:45 a.m. Recruiting and Retaining a Diverse Residency Program

Susan Williams, DVM, PhD*

8:00 a.m.-8:50 a.m. Introduction and Overview of Immune-Mediated Skin Injury

Dimitry Danilenko, DVM, PhD*

8:50 a.m.-9:40 a.m. Cutaneous Hypersensitivity Reactions in NHPChristina Satterwhite, PhD

9:40 a.m.-10:10 a.m. Refreshment Break10:10 a.m.-11:00 a.m. Phototoxicity

Doug Learn, PhD

11:00 a.m.-11:50 a.m. UV-Induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis

Doug Brash, PhD


8:00 a.m.-12:00 noon Mini-Symposium: Forensic PathologySession Chairs: Arno Wuenschmann, DrMedVetSean P. McDonough, DVM, PhD*

8:00 a.m.-8:50 a.m. Traumatic Head Injuries: Mechanisms and Patho-logical Findings in Humans and Animals

Mary E. Case, MD

8:50 a.m.-9:40 a.m. Forensic Pathology of Organized Dog Fighting Jodie Gerdin, DVM*

9:40 a.m.-10:00 a.m. Survey Results on Attitudes of ACVP Diplomates on Forensic Pathology

Beverly McEwan, DVM, MSc, PhD*10:00 a.m.-10:30 a.m. Refreshment Break

10:30 a.m.-11:20 a.m. Gunshot WoundsAndrew Baker, MD

11:20 a.m.-12:00 noon Demystifying the Courtroom: the Role of Veterinary Fact and Expert Witnesses in Animal Cruelty Trials

Reese Frederickson, JD, MBA, BS

8:45 a.m.-9:00 a.m. Resident Mentoring Paige Carmichael, DVM, PhD*

9:00 a.m.-9:15 a.m. Use of Technology in Resident TeachingAmy Durham, DVM, PhD*

7:00 a.m.-5:00 p.m. Speaker Ready Room7:30 a.m.-5:00 p.m. Registration

8:00 a.m.-12:00 noon Concurrent Session IIGenetically Engineered Large Animals

Session Chairs: David K. Meyerholz, DVM, PhD*Katherine Gibson-Corley, DVM, PhD*

8:00 a.m.8:50 a.m. Translational Imaging and Characterization of a TP53 Cancer Model in Yucatan Miniature Pigs

Jessica C. Sieren, PhD

8:50 a.m.-9:40 a.m. Congenital Cerebellar Disease in a Porcine Model of Ataxia Telangiectasia

David Pearce, PhD

Tuesday, October 20 Tuesday (continued)

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2015

*ACVP Diplomate

9:15 a.m.-9:30 a.m. Medical School Training ProgramsNancy Kock, DVM, PhD*

9:30 a.m.-10:00 a.m. Strategies and Success StoriesModerator: Paige Carmichael, DVM, PhD* Krista LaPerle, DVM, PhD*Susan Williams, DVM, PhD*Amy Durham, DVM, PhD*Nancy Kock, DVM, PhD*

10:00 a.m.-10:30 a.m. Refreshment Break10:30 a.m.-10:45 a.m. Mock Boards Creation and Use

Kim Newkirk, DVM, PhD*

10:45 a.m.-11:00 a.m. ACVP Board Examination UpdateElizabeth Howerth, DVM, PhD*

11:00 a.m.-11:30 a.m. Board Exam Myth-BustersPatty Pesavento, DVM, PhD*

11:30 a.m.-12:00 noon The ACVP Board Examination: Questions, Comments, Concerns

Moderator: Linden Craig, DVM, PhD*

PanelistsPatricia Pesavento, DVM, PhD*Nancy Kock, DVM, PhD*Krista LaPerle, DVM, PhD*Anne Barger, DVM, PhD*

Session Disclaimer

This session is for informational purposes only. The advice, opinions, statements, materials, and other information expressed and contained during the session are solely those of the speakers and do not necessarily reflect the views, policies or opinions of the ACVP. The ACVP is not respon-sible for the accuracy, currency, completeness, reliability or usefulness of any advice, opinions, statements or content contained in the session. The ACVP makes no claim that the use of the information provided will assure a successful outcome on the certifying examination.

8:00 a.m.-12:00 noon ASVCP Veterinary Laboratory Professionals Session IIISession Chair: Lynne Shanahan, MT, ASCP

8:00 a.m.-8:30 a.m. SOP Document RequirementsLynne Shanahan, MT, ASCP

8:30 a.m.-9:30 a.m. Comparative ErythrologyDeanna Schaefer, DVM, MS, MT (ASCP)*

9:30 a.m.-10:00 a.m. Refreshment Break10:00 a.m.-11:00 a.m. Update on Novel Urine Biomarkers for Detection

of Glomerular and Tubular Damage in Dogs and Cats

Jessica Hokamp, DVM*

11:00 a.m.-12:00 noon Roundtable DiscussionsStaffing Demands in the Clinical Laboratory

8:00 a.m.-5:00 p.m. Student and Guest Hospitality Room9:00 a.m.-5:00 p.m. Career Center

9:30 a.m.-3:30 p.m. Exhibits and Silent Auction


9:40 a.m.-10:30 a.m. Refreshment Break12:00 noon-1:30 p.m. Lunch Break (on your own)

1:30 p.m.-3:00 p.m. ACVP Examination Re-Design Concept Town Hall Meeting

1:30 p.m.-5:00 p.m. ASVCP and STP Mystery Slide Case SessionSession Chair: Tracy Stokol, DVM, PhD*

1:30 p.m.-5:00 p.m. STP Focused Topic Session 3 Models of Skin Disease

Session Co-Chairs: Robert Dunstan, DVM, MS*Elizabeth Mauldin, DVM, DACVD*

The objective of this session will be to describe the diversity of animal models available to investigate skin diseases. A secondary goal will be to provide a session that will be of interest to both STP and ACVP attendees. This will start with a discussion of in vitro models followed by presentations on the epidermis, the hair follicle, and the dermis. At the end, the attendees should have a better understanding of both dermatopathology and diseases affecting the major structural complements of the skin.

1:30 p.m.-2:15 p.m. In Vitro Epidermal Models and Their Predictability to Define Normal and Disease Biology, Pharmacology, and Toxicity

Dimitry Danilenko, DVM, PhD*

2:15 p.m.-3:05 p.m. The Epidermis and Diseases in Domestic AnimalsElizabeth Mauldin, DVM, DACVD*

3:05 p.m.-3:35 p.m. Refreshment Break3:35 p.m.-4:25 p.m. The Hair Follicle and the Yet Unsolved Mystery of

Non-Inflammatory AlopeciaMonika Welle, Prof. DrMedVet, DECVP

4:25 p.m.-5:00 p.m. The Dermis: Can Animal Models Be Used to Inform the Pathogenesis of Scleroderma?

Robert Dunstan, DVM, MS*

1:30 p.m.-5:00 p.m. Diagnostic Pathology Focused Scientific Session IISession Chair: Stephen Raverty, DVM, PhD*

1:30 p.m.-5:00 p.m. Experimental Disease Focused Scientific Session IISession Chair: Sébastien Monette, DMV, MVSc*

Invited Speakers

Holoprosencephaly, Cleft Lip, and Cleft Palate Result from Acute Hedgehog Signaling Inhibition in the Mouse: Timing is Everything

Robert J. Lipinski, PhD

Modeling the Natural History of Pelizaeus Merz-bacher Disease in a Canine X-Linked Disorder

Ian D. Duncan, BVMS, PhD, FRCPath, FRSE3:00 p.m.-3:35 p.m. Refreshment Break

5:15 p.m.-6:00 p.m. STP Business Meeting

6:15 p.m.-7:30 p.m. Joint ACVP and STP Awards and Recognition Event

7:45 p.m.-10:00 p.m. Presidents’ Reception

Tuesday (continued) Tuesday (continued)

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Preliminary Program

2015

*ACVP Diplomate


7:00 a.m.-11:00 a.m. Speaker Ready Room8:00 a.m.-11:00 a.m. Student and Guest Hospitality Area

8:00 a.m.-1:00 p.m. Registration8:00 a.m.-12:00 noon Young Investigator Award Poster Session

8:00 a.m.-12:00 noon Concurrent Session III Pathology of Avian/Exotics

Session Chairs: Nancy Stedman, DVM, PhDRita McManamon, DVM

8:00 a.m.-8:45 a.m. Select Emerging, Infectious and Poorly Understood Disease Entities of Reptiles

Mike Garner, DVM*

8:45 a.m.-9:15 a.m. Selected Topics in Avian PathologyNancy Stedman, DVM, PhD

9:15 a.m.-9:40 a.m. Selected Topics in Small Mammal PathologyRita McManamon, DVM

9:40 a.m.-10:10 a.m. Refreshment Break10:10 a.m.-10:55 a.m. Current/Selected Topics in Wildlife Pathology

Valerie Shearn-Bochsler, DVM, MPH

10:55 a.m.-11:40 a.m. Emerging Zoonotic Diseases: Critical Role of Pathology in Identification and Discovery

Sherif Zaki, MD, PhD


8:00 a.m.-12:00 noon Concurrent Session IV Flow Cytometry and Clonality Assays in Diagnostic Hematopathology

Session Chairs: Mary Jo Burkhard, DVM, PhD*Dorothee Bienzle, DVM, PhD*

8:00 a.m.-8:05 a.m. IntroductionDorothee Bienzle, DVM, PhD*Mary Jo Burkhard, DVM, PhD*

8:05 a.m.-8:50 a.m. Principles of Flow Cytometry of Human Non-Hodgkin Lymphoma and Applications to Comparative Pathology

Michael Linden, MD, PhD, DABP

8:50 a.m.-9:20 a.m. Concepts and Conundrums of Clinical Flow Cytometry

Mary Jo Burkhard, DVM, PhD*

9:20 a.m.-9:50 a.m. Principles, Potential and Pitfalls of Clonality Testing

Stefan Keller, DVM, PhD, DECVP

9:50 a.m.-10:10 a.m. Current Status of Proficiency Testing and Consensus Effort

Dorothee Bienzle, DVM, PhD*10:10 a.m.-10:25 a.m. Refreshment Break

10:25 a.m.-12:00 noon Flow Cytometry and Clonality Cases to Demonstrate Diagnostic Challenges and Rewards

Melinda Wilkerson, DVM, PhD*Stefan Keller, DMV, PhD, DECVPDorothee Bienzle, DVM, PhD*Mary Jo Burkhard, DVM, PhD*

Tracy Stokol, DVM, PhD*

8:00 a.m.-12:00 noon STP Focused Topic Session 4Case Studies of Cutaneous Toxicity, Direct and Systemic

Session Co-Chairs: Zbigniew Wojcinski, DVM, DVSc, DABT*Duane Belote, DVM*

During development of compounds intended to treat skin diseases, manifestations of cutaneous toxicity may occur after topical application or systemic administration. Many factors, including selection of the appropriate animal model and parameters for evaluation, must be taken into consideration in designing nonclinical safety strategies to support initiation of clinical trials with potential therapeutic compounds.

This session will cover the unique challenges of drug development of compounds intended to treat dermal disease conditions from technical and pathology perspectives. The first presentation will provide an overview of the numerous factors that can influence the conduct of dermal toxicity studies and subsequent interpretation of findings. Subsequent presentations will review case studies related to cutaneous toxicity mediated by anti-body-drug conjugates and an occurrence of toxic epidermal necrolysis in a nonhuman primate.

8:00 a.m.-8:50 a.m. Dermal Toxicity Studies: Factors Impacting Study Interpretation and Outcome

Sundeep Chandra, BVSc, PhD*

8:50 a.m.-9:40 a.m. Primate Studies with Direct and Indirect Toxic Effects on the Skin

Annette Romeike, DMV*9:40 a.m.-10:10 a.m. Refreshment Break

10:10 a.m.- 10:50 a.m. Cutaneous Toxicity in Cynomolgus Monkey Given an Orally Administered Small Molecule

Rie Kikkawa

10:50 a.m.-11:40 a.m. Toxicologic Dermatopathology Case PresentationTBD

8:00 a.m.-12:00 noon Mini-Symposium II: Medical Device PathologySession Chairs: Laura E. Leigh Perkins, DVM, PhD*Marian K. Rippy, DVM, PhD*

8:00 a.m.-8:15 a.m. Welcome to the World of Cardiovascular Medical Devices

Laura E. Leigh Perkins, DVM, PhD*Marian K. Rippy, DVM, PhD*

8:15 a.m.-8:50 a.m. Handling, Processing, and Evaluation of Medical Devices

Serge D. Rousselle, DVM*

8:50 a.m.-9:25 a.m. Medical Device Regulatory Considerations and Biocompatibility

Victoria Hampshire, VMD

9:25 a.m.-10:00 a.m. Medical Device Imaging and the PathologistAmit Vasanji, PhD

10:00 a.m.-10:20 a.m. Refreshment Break

Wednesday, October 21 Wednesday (continued)

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Preliminary Program

2015

*ACVP Diplomate

10:20 a.m.- 10:50 a.m. Cardiovascular and Combination DevicesMarian K. Rippy, DVM, PhD*

10:50 a.m.-11:10 a.m. Morphologic Evaluation of Nervous System Devices

Mark T. Butt, DVM*

11:10 a.m. – 11:30 a.m. Preparation and Analysis of Orthopedic Implanted Devices

Madeleine Chagnon, DVM, MSc

11:30 a.m. – 11:50 a.m. Staying in the Game: Evaluation of Safety and Efficacy of Orthopedic Devices

Joan Wicks, DVM, PhD*


1:00 p.m.-5:00 p.m. ACVP/ASVCP/STP Post-Meeting Workshop I (available at an additional fee)

Case-Based Molecular Pathology Workshop: State-of-the-Art

Session Co-Chairs: David E. Malarkey DVM, MS, PhD, FIATP*Gerry O’Sullivan, MVB, MSc, PhD, MACVSc, DECVP*

Objectives: Provide an interactive learning format to review practical applications that exemplify the current state-of-the-art applications in molecular diagnosis, prognosis, etiology, pathogenesis as well as assessing environmental hazards or toxicity. There will be 7 case-based exercises led by experts in the fields demonstrating useful molecular pathology approaches that solve everyday pathology questions creating data that are used to make clinical or regu-latory decisions. The presentations will focus on data interpretation and analysis rather than on methods, so attendees should have at least a cursory concept of molecular techniques such as PCR, microarray gene expression analysis, qrtPCR, gene mutations, etc. There will be ample time for discussion and ques-tions by each presenter. Each case will be presented and discussed with participants for approximately 20 mins.

1:00 p.m.–1:10 p.m. Overview of Workshop David E. Malarkey DVM, MS, PhD, FIATP*

Gerry O’Sullivan, MVB, MSc, PhD, MACVSc, DECVP*

Case #1:

Utility of Clonality Assays in the Diagnosis of Malignant Lymphoma.

Anne Avery, VMD, PhD

Case #2:

Application of Cytogeneomics for the Diagnosis and Prognosis of Canine Neoplasms

Matthew Breen, PhD

Case #3:

Molecular Biomarkers in Determining the Prognosis of Canine Mast Cell Tumors

Matti Kiupel, DrMedVet, BS, MS, PhD*

Case #4:

Genomics of Rat Liver Cancer: Origin and Evolution of Hepatoblastomas in the Mouse

Arun Kumar R. Pandiri, BVSc & AH, PhD, MS, DABT*

2:30 p.m.-3:00 p.m. Refreshment BreakCase #5: Predictive Gene Profiling of Liver Toxicants and Carcinogens

Scott Auerbach, PhD, DABT

Case #6:

Diagnosis of Porcine Epidemic Diarrhea: Which is the Latest New Important Disease in Swine

Stephanie Rossow, DVM, PhD

Case #7:

Fulfilling Koch’s Postulate: The Role of Molecular Biology in Establishing Illnesses Caused By Bartonellosis

Ricardo Maggi, MS, PhD

4:15 p.m.-4:45 p.m. Panel Discussion with Workshop Faculty

1:00 p.m.-5:00 p.m. Post-Meeting Workshop II (available at an additional fee)Mouse Central Nervous System Neuropathology

Session Chairs: Jerrold M. Ward, DVM, PhD*Caroline Zeiss, BVSc, PhD, DACLAM*

1:00 p.m.-1:45 p.m. Mouse Brain Evaluation: How and Where to Look: An Overview of Mouse Neuroanatomy

Deepa B. Rao, BVSc, PhD, MS, DABT*

1:45 p.m.-2:30 p.m. An Overview of Mouse CNS Neuropathology: Spontaneous Findings, Artifacts, and Selected Induced Lesions

Ingrid D. Pardo, DVM, MS*

2:30 p.m.-3:00 p.m. Break with Review of Digital Slide Cases

3:00 p.m.-3:30 p.m. Mouse Brain Tumors: GEM and Preclinical ModelsJerrold M. Ward, DVM, PhD, FIATP*

3:30 p.m.-4:15 p.m. Translational Preclinical CNS Mouse Models I – Discovery

Caroline Zeiss, BVSc, PhD, DACLAM*

4:15 p.m.-5:00 p.m. Translational Preclinical CNS Mouse Models II – Safety

Ingrid D. Pardo, DVM, MS*

Wednesday (continued) Wednesday (continued)

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ACVP S I LENT AUCT ION

ACVP 2015Silent Auction

TheACVP is proud to present a SilentAuction at the 2015AnnualMeeting!LocatedintheExhibitArea,theSilentAuctionwillsupportexternshipscholarshipsforveterinarystudentsexploringveterinarypathologyasacareer.

TheACVPneeds your donations to helpmake theSilentAuctiona success!Donating to the Auction is a great way to support the veterinary pathologyprofession,andhavefunattheAnnualMeeting.Itemsfrombothmembersandcompaniesarewelcome.

PLUS,bothitemdonorsandwinningbidderswillhavetheirnamesenteredintoadrawing fora free registration to the2016AnnualMeeting inNewOrleans,Louisiana!

RecognitionForyourdonation,youwillreceive:AcknowledgementontheauctionbidsheetsListingofyourdonationandnameontheACVPwebsite

To Make a DonationPleasecompletetheSilentAuctionDonationformandfaxormailittotheACVPExecutiveOffice.

Getting Your Item to the AuctionPleasesendyouritemstotheACVPExecutiveOfficeassoonaspossible(nolaterthanOctober1,2015),alongwithacopyofthedonationformonthebackofthisflyer.WewillshipallitemstotheAnnualMeeting.

FormoreinformationregardingtheACVPAnnualMeetingortheSilentAuction,pleasecallKristinMeicherat+1-608-443-2466,ext.136,[email protected].

Combined Annual Meeting | October 17–21, 2015Minneapolis Convention Center and Hyatt Regency Minneapolis Hotel

www.asvcp.orgwww.acvp.org www.toxpath.org

ACVP | ASVCP | STP

Popular Items to Donate

Allcontributionsarewelcome,includingproductsthatinterestyourfellowcolleaguesprofessionally,aswellaspersonally.Itemsshouldhaveaminimumvalue

of$50USD.Somepopularitemsare:

Vacation Getaways

Books

Electronics

Themed Gift Baskets

Autographed Sports Items

Spa Treatments

Jewelry

Tickets to Social, Cultural or Athletic

Events

Hotel and Time-Share Stays

Professional Equipment and Services

Original Artwork

Gift Certificates to National Restaurants or

Stores

Exclusive and unique items are always a

favorite!

18


ACVP Silent Auction Donation Form 2015

To donate an item for the Silent Auction, pleasereturn this form to ACVP no later than October 1, 2015.

Fax: +1-608-443-2474 or +1-608-443-2478 Email: [email protected] Mail: ACVP, 2424 American Lane, Madison, WI 53704-3102 USA

Please provide information as you would like it to appear in all publications:Name of the Item: __________________________________________________________

Estimated Value ($USD): _____________________________________________________

Donor Name (your name or company): _________________________________________

Description of Item: ____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________

Contact Information (for internal use only):

Name: ___________________________________________________________________

Address: _________________________________________________________________

City: _____________________________________________________________________

State/Province: __________________________ Zip/Postal Code: ___________________

Country: _________________________________________________________________

Phone: __________________________________________________________________

Email: ___________________________________________________________________

*Please send your item(s) to the ACVP Executive Office by October 1, 2015, and include a copy of this form with the auction item.

For more information regarding the ACVP Annual Meeting or the Silent Auction, please callKristin Meicher at +1-608-443-2466, ext. 136, or contact her by email [email protected]. Thank you for your generosity!

S I LENT AUCT ION

19


Obituaries

William (Bill) John Hadlow

William (Bill) John Hadlow, 94, longtime resident of Hamilton, Montana, passed away at his home on Saturday, June 20, 2015.

During his college years, Bill served in the U.S. Army in a specialized training program and then in the U.S. Navy in the Hospital Corps.Dr. Hadlow graduated from the Ohio State University and went on to the University of Minnesota. He was an instructor in the College of Veterinary Medicine during the period 1946-48. He continued his studies in pathology in the Medical School through 1952 and was certified as a veterinary pathologist in 1953. Dr. Hadlow’s main position of employment was as a Research Pathologist in the Public Health Service at the Rocky Mountain Laboratory, Hamilton, Montana. His research interest in comparative pathology was focused on neuropathology, working on the slow viral diseases of Aleutian disease and the transmissible spongiform encephalopathies, such as Mad Cow Disease. Hadlow is described as a giant in the field of comparative neuropathology and is recognized worldwide as an authority on prion disease pathology.

After leaving Rocky Mountain Laboratory, Dr. Hadlow then worked at two animal disease laboratories in England. He fully retired in Hamilton in 2005, completing 50 years of professional work.

Paul Newberne

Paul M. Newberne, 94, of Bedford, Massachusetts, passed away peacefully surrounded by his loving family on March 22, 2015, after a long illness. Paul was born November 4, 1920, on a cotton and peanut farm in southern Georgia. Early on, he learned firsthand the rigors and rewards of growing up on a farm. Determined to acquire an education, he started his illustrious academic career in a three-teacher elementary school within walking distance of his family’s farm. After receiving his high school diploma from the county high school, Paul began his college education at a local community college, interrupting his studies to work on behalf of the American Express Company at the 1939 World’s Fair in New York. His efforts at the World’s Fair allowed him to continue his studies at the University of Georgia, where he completed two years prior to entering the Navy. Paul was a member of the “Greatest Generation,” serving as a Naval Aviator during World War II, from 1942 until 1945. He flew a variety of planes, including the B-17 and B-54.

After serving four years as a Navy pilot, Paul entered the College of Veterinary Medicine at Auburn University, where he received his DVM in 1950. He then earned a Master of Science degree in Veterinary Pathology in 1951. After two years in private practice, he entered a PhD program in Nutritional Biochemistry, with a minor in Human Pathology, at the University of Missouri–Columbia, which he received in 1958. In the same year, Paul returned to Auburn University to direct a laboratory of Experimental Pathology in the Nutrition Department. Paul was certified as a veterinary pathologist in 1960. In 1962, Paul accepted an appointment to the faculty at MIT. Upon his retirement from MIT after 24 years, Paul then became a Professor of Pathology at the Mallory Institute of the Boston University School of Medicine, where he served for 10 years.

Paul was a true academic leader and advised more than 150 students through the years. He mentored more than 50 PhD students into interesting and productive careers. Many of these students were international, so his influence reached the far corners of the world. In particular, his work in the area of Food Nutrition extended to countries as far as Thailand, Turkey, Russia, and Australia, where he worked with governments and food companies to improve the purity of food supplies in emerging countries. Paul was, for many years, a science adviser to the Royal Family of Thailand, where he worked in the area of food nutrition and purity in order to improve the quality of life for the people of Thailand.

The American Collegeof Veterinary Pathologists

TM

2424 American LaneMadison, WI 53704-3102 USA

Phone: +1-608-443-2466Fax: +1-608-443-2474E-Mail: [email protected] Website: http://www.acvp.org

Upcoming Events14th Annual Workshop on the Pathology of Mouse Models for Human DiseaseUniversity of Washington, SeattleSeptember 20-24, 2015

European Society of Toxicologic Pathology in collaboration with the British Society of Toxicological Pathology: 13th European Congress of Toxicologic Pathology, Joint ESTP/BSTP MeetingUniversity of Surrey, UKSeptember 22-25, 2015

Western Conference of Veterinary Diagnostic PathologistsWestern College of Veterinary Medicine, Abbotsford, BCSeptember 25-26, 2015

Safety Pharmacology Society 15th Annual MeetingPrague, Czech RepublicSeptember 28–October 1, 2015The Safety Pharmacology Society (SPS) 15th Annual Meeting will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program will offer in-depth discussions of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two tracks, covering issues on topics such as, Cardiovascular, Central Nervous System, Translational, Integrative Pharmacology, Novel In Vitro Models, as well as sessions covering updates on the Comprehensive In Vitro Proarrhythmia Assay (CIPA) and an NC3Rs workshop on group housing. The meeting also will offer a full day of Continuing Education courses on September 28, both on an introductory level as well as advanced courses for the expert, and the Diplomate in Safety Pharmacology (DSP) Certification exam will be held the day before the meeting on September 27. For preliminary meeting information, please visit the SPS Annual Meeting website.

Pathways to Translational MedicineRecent Advances in Cell Injury, Inflammation, and NeoplasiaBaltimore, MDOctober 8-10, 2015

2015 ACVP Surgery SummitNashville, TNOctober 22-24, 2015

2015 ACVP/ASVCP/STP Combined Annual MeetingOctober 17-21Minneapolis Convention Center, Minneapolis, MNwww.acvp.org

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