Acute Myocardial Infarction (MI) treated with Stemedica Stem Cells (MSC) Kaz. Phase II Results
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Transcript of Acute Myocardial Infarction (MI) treated with Stemedica Stem Cells (MSC) Kaz. Phase II Results
ACUTE MYOCARDIAL INFARCTION STUDY
AMI RESULTS PRESENTED American College of Cardiology – Chicago – 2012
Switzerland (version of FDA) SWISSMEDIC
University of CHUV – Switzerland
Several leading cardiologists & hospitals in US & Europe
Efficacy Data
2
Parameters Experimental Group (N = 19) Control Group (N = 15)Day 1 3 months 6 months Day 1 3 months 6 months
С-Reactive Protein
(mg/mL)
29.9 2.8† 3.6‡ 17.3 14.5 9.2*
(44.7) (1.8) (2.1) (11.3) (6.0) (5.0)
BNP (ng/mL)1731.5 349.6† 186.6‡* 2933.4 1726.6† 946.2‡
(1746.3) (214.4) (110.8) (2457.5) (1205.5) (1028.5)End-diastolic
volume of left ventricle
(mL)
128.1 121.2† 120.1 110.8 110.2 120.2
(43.4) (38.0) (36.2) (28.0) (19.9) (40.3)
End-systolic volume of
left ventricle (mL)
77.1 62.6† 58.3‡ 66.2 59.2 66.8
(38.4) (27.7) (24.3) (39.0) (18.0) (27.4)
Left Ventricular
Ejection Fraction (%)
38.4 52.3† 54.7‡* 38.5 42.8† 46.1‡*
(6.8) (6.8) (5.3) (3.8) (3.1) (5.3)
Mean †: statistically significant, day 1 vs 3 months(Standard Deviation) ‡ statistically significant, day 1 vs 6 months
* statistically significant, 3 months vs 6 months
MRI ResultsPatients: 63 years Diagnosis: AMI (STEMI)Single artery occlusion (LAD) with stenting of infarct related artery
Before After 1months
Treatment of Diabetes II complicationPatients 56 years old with Diabetes II (15 years)
Complication: Atherosclerosis. Occlusion of Femoral Artery
Before After
Treatment of Diabetes II complicationsPatients 61 years old with Diabetes II (20 years)
Complication: Atherosclerosis. Occlusion of Femoral Artery
Before After