A PROSPECTIVE EVALUATION OF “KETOFOL”, KETAMINE & PROPOFOL COMBINATION FOR PROCEDURAL SEDATION &...

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Background Copy and paste your text content here, adjusting the font size to fit. Take care with fonts. We suggest “Arial” as a sans-serif font, or “Time Roman” (not “Time New Roman”) for a serif font. • To evaluate effectiveness and safety of ketofol for procedural sedation and analgesia in ED. •To assess recovery time, staff and patient satisfaction. Aims & Objectives • Forty patients were administered ketofol for painful procedures in ED. • Median dose of Ketofol administered was 0.6 mg/kg (range 0.4 to 1.00 mg/kg; IQR 0.5 to 0.71 mg/kg). • Of the 40 procedures performed, 40 (100%) were completed successfully. • None of patient had hypotension or evidence of poor perfusion. • Median recovery time was 10 minutes (range 5 to 25 minutes; IQR 6.25 to 15 minutes). • In 20 minutes 92.5% of patients recovered. Methods Conclusion Ketofol is easy to use, effective and safe for painful procedures in ED. Recovery time was rapid, staff and patients were very satisfied. Few adverse events occurred and responded to minimal intervention. A PROSPECTIVE EVALUATION OF “KETOFOL” (KETAMINE/PROPOFOL COMBINATION) FOR PROCEDURAL SEDATION & ANALGESIA IN ED Dr.Kesavardhan Reddy Narsing*; Dr. Srihari Cattamanchi; Dr. T,V, Ramakrishnan. Sri Ramchandra Medical College & Research Institute, Porur, Chennai – 600116. Tamil Nadu. India. Results Dr. Kesavardhan Reddy Narsing, Address: ; Mobile: ; Email id:; Design: A Prospective, interventional analytical study. Setting: Accident & Emergency Department, of Sri Ramachandra Medical College & Research Institute, a tertiary care, level I trauma centre in Chennai, India. Duration: 1 st May to 31 st December 2009. Inclusion: All trauma patients above 18 years administered ketofol for procedural sedation and analgesia, and Visual Analog Scale (VAS) pain score of > 6/10 were included. Methodology: Ketofol was prepared as 1:1 mixture of Ketamine and Propofol 10 mg/mL each in 10-mL syringe and 1 - 3 mL administered. Recovery Time Calculated. Instrument: Likert's Scale used to record Doctor's Likert Scale 2 5.0 5.0 5.0 38 95.0 95.0 100.0 40 100.0 100.0 Satisfied Very Satisf Total Valid Frequency Percent alid Percent Cumulative Percent Patient’s Likert Scale Satisfied Very Satisf Frequency Percent alid Percent Percent Drug Descriptive Statistics Estimated Value Ketamin e Mean +/- S.D. 0.61 +/- 0.14 Median (Range) 0.61 (0.60) Minimum 0.40 Maximum 1.00 Inter- quaretile Range 0.50 to 0.71 Propofo l Mean +/- S.D. 0.61 +/- 0.14 Median (Range) 0.61 (0.60) Minimum 0.40 Maximum 1.00 Inter- quaretile Range 0.50 to 0.71

Transcript of A PROSPECTIVE EVALUATION OF “KETOFOL”, KETAMINE & PROPOFOL COMBINATION FOR PROCEDURAL SEDATION &...

Page 1: A PROSPECTIVE EVALUATION OF “KETOFOL”, KETAMINE & PROPOFOL COMBINATION FOR PROCEDURAL SEDATION & ANALGESIA IN ED

BackgroundCopy and paste your text content here, adjusting the font size to fit.

Take care with fonts. We suggest “Arial” as a sans-serif font, or “Time Roman” (not “Time New Roman”) for a serif font.

• To evaluate effectiveness and safety of ketofol for procedural sedation and analgesia in ED.•To assess recovery time, staff and patient satisfaction.

Aims & Objectives

• Forty patients were administered ketofol for painful procedures in ED.

• Median dose of Ketofol administered was 0.6 mg/kg (range 0.4 to 1.00 mg/kg; IQR 0.5 to 0.71 mg/kg).

• Of the 40 procedures performed, 40 (100%) were completed successfully.

• None of patient had hypotension or evidence of poor perfusion.

• Median recovery time was 10 minutes (range 5 to 25 minutes; IQR 6.25 to 15 minutes).

• In 20 minutes 92.5% of patients recovered.

Methods

ConclusionKetofol is easy to use, effective and safe for painful procedures in ED. Recovery time was rapid, staff and patients were very satisfied. Few adverse events occurred and responded to minimal intervention.

A PROSPECTIVE EVALUATION OF “KETOFOL” (KETAMINE/PROPOFOL COMBINATION)

FOR PROCEDURAL SEDATION & ANALGESIA IN ED Dr.Kesavardhan Reddy Narsing*; Dr. Srihari Cattamanchi; Dr. T,V, Ramakrishnan.

Sri Ramchandra Medical College & Research Institute, Porur, Chennai – 600116. Tamil Nadu. India.

Results

Dr. Kesavardhan Reddy Narsing, Address: ; Mobile: ; Email id:;

Design: A Prospective, interventional analytical study.

Setting: Accident & Emergency Department, of Sri Ramachandra Medical College & Research Institute, a tertiary care, level I trauma centre in Chennai, India.

Duration: 1st May to 31st December 2009.

Inclusion: All trauma patients above 18 years administered ketofol for procedural sedation and analgesia, and Visual Analog Scale (VAS) pain score of > 6/10 were included.

Methodology: Ketofol was prepared as 1:1 mixture of Ketamine and Propofol 10 mg/mL each in 10-mL syringe and 1 - 3 mL administered. Recovery Time Calculated.

Instrument: Likert's Scale used to record satisfaction ratings.

Statistical Analysis: done using SPSS software Ver. 17.

Doctor's Likert Scale

2 5.0 5.0 5.0

38 95.0 95.0 100.0

40 100.0 100.0

Satisfied

Very Satisfied

Total

ValidFrequency Percent Valid Percent

CumulativePercent

Patient’s Likert Scale

10 25.0 25.0 25.0

30 75.0 75.0 100.0

40 100.0 100.0

Satisfied

Very Satisfied

Total

ValidFrequency Percent Valid Percent

CumulativePercent

Drug Descriptive Statistics

Estimated Value

Ketamine Mean +/- S.D. 0.61 +/- 0.14

Median (Range) 0.61 (0.60)

Minimum 0.40

Maximum 1.00

Inter-quaretileRange

0.50 to 0.71

Propofol Mean +/- S.D. 0.61 +/- 0.14

Median (Range) 0.61 (0.60)

Minimum 0.40

Maximum 1.00

Inter-quaretile Range

0.50 to 0.71