A PROSPECTIVE EVALUATION OF “KETOFOL”, KETAMINE & PROPOFOL COMBINATION FOR PROCEDURAL SEDATION &...
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Transcript of A PROSPECTIVE EVALUATION OF “KETOFOL”, KETAMINE & PROPOFOL COMBINATION FOR PROCEDURAL SEDATION &...
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• To evaluate effectiveness and safety of ketofol for procedural sedation and analgesia in ED.•To assess recovery time, staff and patient satisfaction.
Aims & Objectives
• Forty patients were administered ketofol for painful procedures in ED.
• Median dose of Ketofol administered was 0.6 mg/kg (range 0.4 to 1.00 mg/kg; IQR 0.5 to 0.71 mg/kg).
• Of the 40 procedures performed, 40 (100%) were completed successfully.
• None of patient had hypotension or evidence of poor perfusion.
• Median recovery time was 10 minutes (range 5 to 25 minutes; IQR 6.25 to 15 minutes).
• In 20 minutes 92.5% of patients recovered.
Methods
ConclusionKetofol is easy to use, effective and safe for painful procedures in ED. Recovery time was rapid, staff and patients were very satisfied. Few adverse events occurred and responded to minimal intervention.
A PROSPECTIVE EVALUATION OF “KETOFOL” (KETAMINE/PROPOFOL COMBINATION)
FOR PROCEDURAL SEDATION & ANALGESIA IN ED Dr.Kesavardhan Reddy Narsing*; Dr. Srihari Cattamanchi; Dr. T,V, Ramakrishnan.
Sri Ramchandra Medical College & Research Institute, Porur, Chennai – 600116. Tamil Nadu. India.
Results
Dr. Kesavardhan Reddy Narsing, Address: ; Mobile: ; Email id:;
Design: A Prospective, interventional analytical study.
Setting: Accident & Emergency Department, of Sri Ramachandra Medical College & Research Institute, a tertiary care, level I trauma centre in Chennai, India.
Duration: 1st May to 31st December 2009.
Inclusion: All trauma patients above 18 years administered ketofol for procedural sedation and analgesia, and Visual Analog Scale (VAS) pain score of > 6/10 were included.
Methodology: Ketofol was prepared as 1:1 mixture of Ketamine and Propofol 10 mg/mL each in 10-mL syringe and 1 - 3 mL administered. Recovery Time Calculated.
Instrument: Likert's Scale used to record satisfaction ratings.
Statistical Analysis: done using SPSS software Ver. 17.
Doctor's Likert Scale
2 5.0 5.0 5.0
38 95.0 95.0 100.0
40 100.0 100.0
Satisfied
Very Satisfied
Total
ValidFrequency Percent Valid Percent
CumulativePercent
Patient’s Likert Scale
10 25.0 25.0 25.0
30 75.0 75.0 100.0
40 100.0 100.0
Satisfied
Very Satisfied
Total
ValidFrequency Percent Valid Percent
CumulativePercent
Drug Descriptive Statistics
Estimated Value
Ketamine Mean +/- S.D. 0.61 +/- 0.14
Median (Range) 0.61 (0.60)
Minimum 0.40
Maximum 1.00
Inter-quaretileRange
0.50 to 0.71
Propofol Mean +/- S.D. 0.61 +/- 0.14
Median (Range) 0.61 (0.60)
Minimum 0.40
Maximum 1.00
Inter-quaretile Range
0.50 to 0.71