A MR Compatible Pressure Transducer with Data Acquisition Software Program
description
Transcript of A MR Compatible Pressure Transducer with Data Acquisition Software Program
A MR Compatible Pressure A MR Compatible Pressure Transducer with Data Acquisition Transducer with Data Acquisition
Software ProgramSoftware Program
Mark CroweMark CroweViral PatelViral Patel
Advisor: Dr. David PickensAdvisor: Dr. David Pickens
Project PurposeProject Purpose
The goal of this project is to design The goal of this project is to design and build a pressure transducer to and build a pressure transducer to measure vasodilation patterns in measure vasodilation patterns in males with hypersexuality disorder males with hypersexuality disorder that can function in a MR environment that can function in a MR environment and also create a software program and also create a software program for data acquisition and storage. for data acquisition and storage.
Hypersexuality: seen as an out of control pattern of sexual thinking and acting, driven by anxiety reduction rather than desire, as a disorder similar to chemical addiction and closely related to obsessive-compulsiveness, and as a attributable to early childhood abuse and/or neglect.
Project BackgroundProject Background Joint study between Department of Joint study between Department of
Psychiatry and Department of Radiology.Psychiatry and Department of Radiology.
fMRI used to determine whether similar fMRI used to determine whether similar brain regions are activated by visual, brain regions are activated by visual, sexual, and drug-related stimuli. sexual, and drug-related stimuli.
This study can lead to scientific information This study can lead to scientific information concerning the cause and effect of concerning the cause and effect of pathological hypersexuality. pathological hypersexuality.
fMRIfMRI fMRI is a technique for fMRI is a technique for
determining the region of the determining the region of the brain activated due to physical brain activated due to physical sensation or activity.sensation or activity. Based on increased blood flowBased on increased blood flow
The active brain regions of The active brain regions of these patients will be these patients will be compared sexual arousal compared sexual arousal activation maps in normal activation maps in normal males. males.
Market PotentialMarket Potential This is a built-to-suit device and will This is a built-to-suit device and will
only be used for research purposes. only be used for research purposes. No opportunity for individual consumer No opportunity for individual consumer
sales.sales. An effort could be made to contact the An effort could be made to contact the
largest research sites for fMRI around the largest research sites for fMRI around the country.country.
Possible use for testing impotencePossible use for testing impotence Requires input from urologists Requires input from urologists
BudgetBudget Vanderbilt’s Department of Psychiatry provided:Vanderbilt’s Department of Psychiatry provided:
$200 pressure transducer$200 pressure transducer $50 sphygmomanometer$50 sphygmomanometer
Vanderbilt’s Department of Radiology provided:Vanderbilt’s Department of Radiology provided: Computer with DaisyLab installedComputer with DaisyLab installed OscilloscopeOscilloscope Plastic tubingPlastic tubing
Any unforeseen costs will be covered by the Psychiatry Any unforeseen costs will be covered by the Psychiatry Dept.Dept. Once project is shown to function properly, a new computer Once project is shown to function properly, a new computer
system will be bought solely for the use of this study.system will be bought solely for the use of this study.
Experiment StructureExperiment Structure
Stimulus(Video) Projected onto Screen
Subject watches video while in MR magnet
Change of pressure in cuff
Vasodilation occurs
Project SchematicProject Schematic
Cuff Pressure Transducer
Amplifier
Data AcquisitionCard
Computer
Calibration of TranducerCalibration of Tranducer
Calibration of Pressure Transducery = 0.0168x - 0.0658
R2 = 0.9997
01234
0 50 100 150 200
Pressure (mm Hg)
Vo
lta
ge
(V
)
Calibration with 20ft TubingPressure (mm Hg) Voltage (V)
20 0.340 0.5960 0.9380 1.29100 1.6120 1.95140 2.28160 2.64180 2.97
Change of 0.336 V for every 20 mm Hg increase
Project DescriptionProject Description
The pressure The pressure transducer is connected transducer is connected to the cuff and to the to the cuff and to the gauge of a gauge of a sphygmomanometer.sphygmomanometer.
Project DescriptionProject Description
Pressure measurement from Pressure measurement from transducer is sent to an transducer is sent to an amplifier with a coaxial amplifier with a coaxial output for the signal.output for the signal.
Signal sent to computer via Signal sent to computer via data acquisition chip.data acquisition chip.
Project DescriptionProject Description
Pressure measurement from Pressure measurement from transducer is sent to an transducer is sent to an amplifier with a coaxial amplifier with a coaxial output for the signal.output for the signal.
Signal sent to computer via Signal sent to computer via data acquisition chip.data acquisition chip.
DaisyLab program created to DaisyLab program created to acquire and store acquire and store measurements.measurements.
Project DescriptionProject Description Pressure measurement from Pressure measurement from
transducer is sent to an transducer is sent to an amplifier with a coaxial amplifier with a coaxial output for the signal.output for the signal.
Signal sent to computer via Signal sent to computer via data acquisition chip.data acquisition chip.
DaisyLab program created to DaisyLab program created to acquire and store acquire and store measurements.measurements. Data acquired in real-time.Data acquired in real-time.
Project DescriptionProject Description Pressure measurement from Pressure measurement from
transducer is sent to an transducer is sent to an amplifier with a coaxial output amplifier with a coaxial output for the signal.for the signal.
Signal sent to computer via Signal sent to computer via data acquisition chip.data acquisition chip.
DaisyLab program created to DaisyLab program created to acquire and store acquire and store measurements.measurements. Data acquired in real-time.Data acquired in real-time. Measurements and time of Measurements and time of
occurrence stored in a text file for occurrence stored in a text file for later analysis with Microsoft later analysis with Microsoft Excel.Excel.
The MR environmentThe MR environment
Effect of magnetic field on signal?Effect of magnetic field on signal?
Will tubing cause problems with Will tubing cause problems with SNR?SNR?
Project StatusProject Status
Pressure transducer Pressure transducer has been assembled has been assembled and calibrated.and calibrated.
A software program A software program has been created has been created with DaisyLab for with DaisyLab for data acquisition.data acquisition.
Balloon Testing is Balloon Testing is complete.complete.
Project StatusProject Status
Device tested on patient outside of Device tested on patient outside of MR environmentMR environment
Device tested on patient in MR Device tested on patient in MR environmentenvironment
Current/Future WorkCurrent/Future Work Modifying software program so that ECG Modifying software program so that ECG
data can also be recorded.data can also be recorded. Complete by March 15Complete by March 15
Construction of a container for the device Construction of a container for the device components.components. Complete by March 15Complete by March 15
Write program for Write program for
new computernew computer