A Convenient Synthesis of 3-Amino-4-imino(thioxo)-imidazolidin-2-ones.

1
2005 Imidazole derivatives R 0190 A Convenient Synthesis of 3-Amino-4-imino(thioxo)-imidazolidin-2-ones. — Subsequent reaction of α-aminonitriles of type (I) and (VI) with activated carbonyl reagents, hydrazines and a base results in a one-pot synthesis of the title compounds, required as pharmacological materials. — (KURZ*, T.; WIDYAN, K.; Tetrahedron Lett. 45 (2004) 38, 7049-7051; Inst. Pharm., Univ. Hamburg, D-20146 Hamburg, Germany; Eng.) — Mais 02- 111

Transcript of A Convenient Synthesis of 3-Amino-4-imino(thioxo)-imidazolidin-2-ones.

Page 1: A Convenient Synthesis of 3-Amino-4-imino(thioxo)-imidazolidin-2-ones.

2005

Imidazole derivativesR 0190 A Convenient Synthesis of 3-Amino-4-imino(thioxo)-imidazolidin-2-ones. —

Subsequent reaction of α-aminonitriles of type (I) and (VI) with activated carbonyl reagents, hydrazines and a base results in a one-pot synthesis of the title compounds, required as pharmacological materials. — (KURZ*, T.; WIDYAN, K.; Tetrahedron Lett. 45 (2004) 38, 7049-7051; Inst. Pharm., Univ. Hamburg, D-20146 Hamburg, Germany; Eng.) — Mais

02- 111

Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in ......et al., 2006, 2009; Ramsbeck et al., 2013), PQ912 [(S)-1-(1H-benzo[d]imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one]

Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in ......et al., 2006, 2009; Ramsbeck et al., 2013), PQ912 [(S)-1-(1H-benzo[d]imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one]

Imino sugars and perturbation of protein folding pathways in the ER Dom Alonzi.

Imino sugars and perturbation of protein folding pathways in the ER Dom Alonzi.

INTRODUCTIONshodhganga.inflibnet.ac.in/bitstream/10603/53915/5/05_chapter 1.pdf · The reaction of amino acids, proteins, peptides, imino acids and amines with triketohydrindine hydrate

INTRODUCTIONshodhganga.inflibnet.ac.in/bitstream/10603/53915/5/05_chapter 1.pdf · The reaction of amino acids, proteins, peptides, imino acids and amines with triketohydrindine hydrate

A Practical Approach to Semicarbazone and Hydrazone ... · A Practical Approach to Semicarbazone and Hydrazone Derivatives via Imino-isocyanates By Keira Garland Thesis submitted

A Practical Approach to Semicarbazone and Hydrazone ... · A Practical Approach to Semicarbazone and Hydrazone Derivatives via Imino-isocyanates By Keira Garland Thesis submitted

Discovery of 2 (6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4- … · 2015. 6. 22. · Activity Relationship (SAR) Studies. Propylthiouracil (PTU, Figure 1) is an inhibitor of TPO

Discovery of 2 (6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4- … · 2015. 6. 22. · Activity Relationship (SAR) Studies. Propylthiouracil (PTU, Figure 1) is an inhibitor of TPO

Resistenz-Entwicklung gegen Desinfektionsmittel in der ... · Imino-, Amid-, Carboxyl-und Thiolgruppen •Zerstörung von Zytoplasma-membranen und Denaturierung von Proteinen und

Resistenz-Entwicklung gegen Desinfektionsmittel in der ... · Imino-, Amid-, Carboxyl-und Thiolgruppen •Zerstörung von Zytoplasma-membranen und Denaturierung von Proteinen und

Poly(aryl imino sulfone)s as new high-performance ... · ORIGINAL PAPER Poly(aryl imino sulfone)s as new high-performance engineering plastics Guanjun Chang • Xuan Luo • Yi Xu

Poly(aryl imino sulfone)s as new high-performance ... · ORIGINAL PAPER Poly(aryl imino sulfone)s as new high-performance engineering plastics Guanjun Chang • Xuan Luo • Yi Xu

Preparation of Imidazolidin4ones and Their …doc.rero.ch/record/29130/files/fro_pie.pdfPreparation of Imidazolidin-4-ones and Their Evaluation as Hydrolytically Cleavable Precursors

Preparation of Imidazolidin4ones and Their …doc.rero.ch/record/29130/files/fro_pie.pdfPreparation of Imidazolidin-4-ones and Their Evaluation as Hydrolytically Cleavable Precursors

Crystal structure of [1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2 ... · ISSN 2056-9890. Currently, there is only scarce information about the synthesis and application in the metathesis

Crystal structure of [1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2 ... · ISSN 2056-9890. Currently, there is only scarce information about the synthesis and application in the metathesis

antibacterial activity thioxo[1,3,5]oxadiazocines ... · thiourea (4.72 g, 62 mmol), cyclohexanone (6.48 g, 66 mmol) and a few drops of hydrochloric acid (37%) in ethanol (40 mL)

antibacterial activity thioxo[1,3,5]oxadiazocines ... · thiourea (4.72 g, 62 mmol), cyclohexanone (6.48 g, 66 mmol) and a few drops of hydrochloric acid (37%) in ethanol (40 mL)

Synthesis and Characterization of [2-(carboxy methylene-amino)- phenyl imino] acetic acid (L) and its some metal complexes Dr. Jasim Shihab. Sultan*, prof.

Synthesis and Characterization of [2-(carboxy methylene-amino)- phenyl imino] acetic acid (L) and its some metal complexes Dr. Jasim Shihab. Sultan*, prof.

Ethyl 2-{(2Z)-2-[(1-naphthylsulfonyl)imino]-2,3-dihydro-1,3-thiazol-4 … · 2017. 3. 23. · Ethyl 2-{(2Z)-2-[(1-naphthylsulfonyl)-imino]-2,3-dihydro-1,3-thiazol-4-yl}-acetate monohydrate

Ethyl 2-{(2Z)-2-[(1-naphthylsulfonyl)imino]-2,3-dihydro-1,3-thiazol-4 … · 2017. 3. 23. · Ethyl 2-{(2Z)-2-[(1-naphthylsulfonyl)-imino]-2,3-dihydro-1,3-thiazol-4-yl}-acetate monohydrate

7KLV Imino Ester and Methyleneindolinones Copper(I ...

7KLV Imino Ester and Methyleneindolinones Copper(I ...

)URQWLHUV 7KLVMRXUQDOLV WKH3DUWQHU2UJDQLVDWLRQV · 444.1534, found 445.1526; IR (ATR) see attached spectra. (Z)-(2-phenyl-1-((2,3,5,6-tetrafluoro-4-(methoxycarbonyl)phenyl)imino)ethyl)-D-alanine

)URQWLHUV 7KLVMRXUQDOLV WKH3DUWQHU2UJDQLVDWLRQV · 444.1534, found 445.1526; IR (ATR) see attached spectra. (Z)-(2-phenyl-1-((2,3,5,6-tetrafluoro-4-(methoxycarbonyl)phenyl)imino)ethyl)-D-alanine

Denitrative Imino-Diaza-Nazarov Cyclization: Synthesis of ... · 1 Denitrative Imino-Diaza-Nazarov Cyclization: Synthesis of Pyrazoles Balakrishna Aegurla, Nisha Jarwal and Rama Krishna

Denitrative Imino-Diaza-Nazarov Cyclization: Synthesis of ... · 1 Denitrative Imino-Diaza-Nazarov Cyclization: Synthesis of Pyrazoles Balakrishna Aegurla, Nisha Jarwal and Rama Krishna

Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5 ...

Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5 ...

Coordinate Derivatives Author Manuscript NIH Public Access ... · Bis(imino)pyridine Iron Dinitrogen Compounds Revisited: Differences in Electronic Structure Between Four- and Five-Coordinate

Coordinate Derivatives Author Manuscript NIH Public Access ... · Bis(imino)pyridine Iron Dinitrogen Compounds Revisited: Differences in Electronic Structure Between Four- and Five-Coordinate

USO DE UNA CICLOADICIÓN IMINO DIELS-ALDER EN LA SÍNTESIS ...

USO DE UNA CICLOADICIÓN IMINO DIELS-ALDER EN LA SÍNTESIS ...

Epirubicin-[Anti-HER2/neu] Synthesized with an …file.scirp.org/pdf/JCT20110100004_87151468.pdf24 Epirubicin-[Anti-HER2/neu] Synthesized with an Epirubicin-(C -imino)-EMCS Analog:

Epirubicin-[Anti-HER2/neu] Synthesized with an …file.scirp.org/pdf/JCT20110100004_87151468.pdf24 Epirubicin-[Anti-HER2/neu] Synthesized with an Epirubicin-(C -imino)-EMCS Analog:

Synthesis and Structure Elucidation of 4-(4-Amino-5-thioxo ...downloads.hindawi.com/journals/chem/2010/904823.pdf · Heterocyclic compounds particularly five and six member ring derivatives

Synthesis and Structure Elucidation of 4-(4-Amino-5-thioxo ...downloads.hindawi.com/journals/chem/2010/904823.pdf · Heterocyclic compounds particularly five and six member ring derivatives