A Clinical Study on Aya Bringaraja Karpam in Veluppu Noi
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Transcript of A Clinical Study on Aya Bringaraja Karpam in Veluppu Noi
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8/11/2019 A Clinical Study on Aya Bringaraja Karpam in Veluppu Noi
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M
S.Vol.XX, No. 1-2, (1999) pp. 83-88
t'VJJ
7*
' C M l C A L S T U D Y
tin Mi
BRINGARAJA
KARPAM IN
VELUPPU
NOI
m-
K. Ganapathiraman
1
, J. Annathai
2
and K. Sivaprakasam
3
(Received on 2-11-99)
clinical study on Ay a Bringaraja
im in the treatment ofVeluppu Noi
inducted in I.P.D. level. A total
Herof 321VeluppuNoi patients were
ted with the trial drug A y a Bringaraja
m at a dose of260mgs.three timesa
to evolveits therape utic efficacy.
Periodical assessment and routine
oratory investigations such as Hb ,
PCV, MC V, urine and motion
inations were also carriedout. It has
observed that the Ranjaka Pitham
pihala Pitham have been mainly
I in VeluppuNo i patients. The trial
|gives a significant effect in the
ition of Veluppu Noi (A condition
or less similar in the hypochronic
icrocyticanaemia).
IK; *
i p :
Introduction
Veluppu Noi (anaemia) is one among
tbe common d iseases, which predominently
seai in most of the people. Though the
VeluppuNoi (anaemia) is a symptom ofa
disease as per modern aspect, the ancient
Siddhars included it as a disease in their
texts. In which, explains that this disease
also occurs due to Karma and it is also
called asKarma Noi.
In this clinical study it has been
observed that the
Ranjaka Pitham
and
Anala Pitham have been mainly affected
due to extrinsic and intrinsic factors. A
total number of 321 cases in both sexes
were studied in I.P.D . level. In a sequential
study
Aya B ringaraja Karpam
was taken
upfo r the clinical trial to evolve the efficacy
of the drug in Veluppu Noi.
Materials and Methods
A total number of 321
Veluppu Noi
patients were studied in I.P.D. level. Both
male and female patients having
low
I. Research Officer
|L Asst. Rese arch Off icer
Assistant Director
begional Res earch Institute (Siddha ), Central Coun cil for Resea rch in Ayurveda and Siddha, G ovt.
barmacy (Ups) Indira Nagar, Pondicheny-6
83
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K. GANAPATHERAMAN, et al.
percentage of heamoglobin between 40%
and 60 % were admitted for the study,
laboratory findings were recorded before
and after treatment.
The patients were kept for observation
on the first day and they were given
Megana tha Mathirai was administred and
in the next day m orning with hot water a t
empty stomach according to the patient's
condition as a purgative. The patients who
were suffering from worms infestation were
given
Murukkan VithaiMathirai.
The trial drugAy a Bringaraja Karpam
260 mgs. was administred three times a
day with honey. During the course of
treatment patients werecarefullyexamined
and symptomatic treatment were also given.
Ordinary Indian diet was given containing
egg, meat, green vegetables and fruits.
Clinical progress was assesed by the
periodical laboratory investigation.
Results and observation :
In this clinical study it has been
observed that the various aspect such as
sex, age, Prakruthi, symptom wise
distribution, etc. The details of studies
given below in (Tables 1 to 7).
Table 1
Sex distribution in 321 cases of
Vellupu Noi
Sex
Number of patients
Male
Female
119
202
Table 2
Distribution of 321 case of VellupuNc
in different age groups 1
Age group
Number of
(age in years)
patients ^
10-20
-ii
106
21-30
63
31-40
53 1
i-i
41-50
56
51-60 42
60 andabove 1 J
Table 3
Classification of
Prakruthi
in 321 cases
of Vellupu Noi J
Prakruthi Num ber of
patient v
Valha Udal
Pitha Udal
Kaba Udal
Thontha Udal
80
102
78
41
{
4
Table 4
Duration of illness in 321
Vellupu Noi
case
i .w;
4
Duration
(in months)
Number of
patient
T
0 1
1-4
5-8
9-12
More than1 year
8
49
96
80
88
m
j j
iU
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CLINICAL ST UD Y Obi Y BRING R J KARPAM W V LUPPUNOI
3 * Table 5
wise classification of 321 cases
1
of VellupuNoi
Liii
Number of
patient
57
111
110
42
1
Table 6
W&M J..
if Duration of treatment in 321
V n ; Vellupu Noi cases
it,
Number of
cases
'{'I
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K. GANAPATHIRAMAN, et al.
improvement was noted in the patients.
The results are given at (Table-8).
Discussion
An attempt
has
been made in the present
study about the various aspects of the
Veluppu
Noi
from the view point of Siddha
concept. The trial drug
Ay a Bringaraja
Karpam has been taken up to evolve its
efficacy in the treatment ofVeluppuNoi,
which was prepared by IMPCO PS, Adayar-
Chennai, having the combination of herbs
and minerals. It w as also noticed, that there
were more number ofPitha Udalpatients,
in present study. The efficacy of the
treatment shows significantly well in
conformity with clinical observation of
signs and symptoms. Out of321patients
122 complete relief, 125 moderate relief,
11 mild relief and 63 patients had left
against medical advice. In this study the
mean haemoglobin valuewas48.7% before
treatment and 72.6% after treatment.
It was observed that more number of
patients had pallor of the skin due to
derangement of Pirasaka Pitham and
Ranjaka Pitham. These two factors are
mainly responsible for the colour of the
skin and
blood.
Since the
Ranjaka Pitham
is in the stomach it gives red colour to the
absorbed food material suchasRasaby the
intestine. Pirasaka and Ranjaka Pitham
have also been found affected in this
condition.
301
patients had loss of appetite due to
impairment of
Analapitham,
which, helps
in the digestion of food.
120 cases had dyspnoea on exerticjj
due to derangement of Pram V ^ f ^
oxygen. All the 131 patients had kg
number of red blood corpuscles who.ag
responsible to carry oxygen to van.
parts of the body. As the R .B.C . a re less
Veluppu Noipatients, the transportation
oxygen is considerably reduced which
inturn leads to dyspnoea.
On observation of SevenUdalDhathus
that a l l pat ien ts were subjected to
defficieney of
Rasa Dhathu
and
Raktha
Dhathu.
The deficiency of
RakthaDhathu
was found out through the signs pallorof
the skin, eye and nail beds. It was also
confirmed by the laboratory findings
t h
the all patients showed low percentage,
HB and RBC.
When the digestion is impaired,
is less possibility fo r the forma tion ofRasa
Dhathu. Rasa DhathuandRakthaDhathu
are the basic factors for the formation of
other Dhathu. The Raktha Dhathu takes
place a vital role in
Veluppu Noi.
Conclusion
In this study it is observed the
malnutrition is the main cau se f orVeluppn\
Noi. Poor socio economic conditions and
f-
excess bleeding during the menstrual cycle,
frequent delivery and worm in festationare,-
seen to be the m ain causative fac tors of his??
disease. The clinical study was made in-
various aspects with relevant factors. Thg
/S:
characteristic of
Raktha Dhathu
and
Rasa
Dhathu
aiid- its fo rm atio n hav e been
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[CLINICAL STUDY
ON Y BRING R J KARPAM I
N
VALUPPUNOI
plained in Siddha aspects. In this study
found that more female patients
|affected than males. The e fficacy of
i
treatment is well in conformity with the
ion of clinicalsignsand symptoms.
therapeutic value ofAya Bringaraja
irpamwas also assessed. T he results are
at (Table 8).
Acknowledgement
The authors are very grateful to the
Director, Central Council for Research in
Ayurveda and Siddha, New Delhi for his
encouragement & financial assistance.
Authors also thanks to Sh. V. R ajendran,
UDC and Sh. George Joseph, GDA for
their secretarial assistance.
REFERENCES
if
lyan, C. S.
h
r, Kuppu Samy &
lyan, C.S.
ludaliar, Kuppu Samy
rnga Velu, M.
Yugimuni
1975 Agasthiar Paripooranam400, P. 47 &
48, Rathina Nay ak K ar and Sons.
1953 SiddhaMaruthu Vanga Page 50 to 58
& 60 , Churukkam, G ovt. Press. Tamil
Nadu.
1966 Siddha VaidyaThiratha
3rd,
Edn., Page
234, Shunmuga Nande Book shop
1954 Siddha Maruthuvam, P. 263 & 269,
Govt. Press, Tam il Nadu.
1967 NoiNadal NoiMudalNadal, Part II, P.
201-202, Govt, press, Tamil Nadu.
1969
Yugimnivar Viadya Chinthamani
, P.
112 &. 114, B. Rathina Nayak Kar &
Sons.
87
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K. GANAPATHTRAMAN, et al.
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