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NONINSULIN
DEPENDENT DIABETESMELLITUS
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GrandpaU
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U(+)
Grandpa
(+)
98-age
U(+)
U(+) DM
Father
(+)
88-age
Mother80
42
48
54
58
(+)TB
38DM
Patient44
4650
525660 (+)
hepatitis
Female
male
deceased
Unknown
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Complete blood Count
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Hypoglycemic
coma
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Route and Dosage IndicationsIV/IM: ADULTS, ELDERLY: 1.2-1.8 g/day in 2-4 divided doses. CHILDREN: 25-40mg/kg/day in 3-4 divided doses.Maximum: 4.8 g/day.
PO: ADULTS, ELDERLY: 150-450 mg/doseq6-8h. CHILDREN: 10-30 mg/kg/day in 3-4divided doses. Maximum: 1.8 g/day.
Bacterial VaginosisIntravaginal: ADULTS: One applicatorful atbedtime for 3-7 days or 1 suppository at
bedtime for 3 days.
PO: ADULTS, ELDERLY: 300 mg 2 times/dayfor 7 days.
Acne VulgarisTopical: ADULTS: Apply thin layer 2
times/day to affected area.
Treatment of respiratory
tract, skin or soft tissue,
chronic bone or joint
infections; septicemia; intra-abdominal, female
genitourinal infections;
bacterial vaginosis;
endocarditis. Can be used
for acne vulgaris.Clindamycin is used for
treatment of malaria, otitis
media, Pneumocystis carinii
pneumonia, and
toxoplasmosis.
Action Containdications
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Action Containdications
Bacteriostatic.
Clindamycin binds tobacterial ribosomal
receptor sites.
Topically, it decreases
fatty acid
concentration on skin.
It inhibits protein
synthesis of bacterialcell wall and prevents
outbreak of acne
vulgaris.
Containdicated with
allergy toclindamycin,
lactation.
Use cautiously in
newborns and infantsdue to benzyl alcohol
content(associated
with gasping
syndrome) and in
patients with tartrazine
sensitivity or hepatic
or renal impairment.
Sid Eff t Ad Eff t
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Side Effects Adverse Effects
Abdominal pain
Nausea and VomitingDiarrhea
Vaginitis and itching
Dry scaly skin
Phlebitis,thrombophlebitis with IVadministration
Pain, induration, at the IMinjection site
Allergic reaction,urticaria, pruritus
Headache and dizziness
Contact dermatitis
Hypersensitivity reaction
Antibiotic-associated
colitis (Severe abdominalpain, tenderness, fever,watery and severediarrhea)
Blood dyscrasias(Leukopenia andthrombocytopenia)
Nephrotoxicity(Proteinuria, azotemia,
oliguria)
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Store capsules at room temperature After reconstitution, oral solution is stable for 2
weeks at room temperature.
Do not refrigerate oral solution to avoid thickening. Give with 8 oz water.
Question patient for history of allergies, particularlyto clindamycin, lincomycin, and aspirin. Avoid concurrent use of neuromuscular blocking
agents. Monitor bowel activity, stool consistency; report
diarrhea promptly due to potential for seriouscolitis. Assess skin for rash with topical application. Assess for superinfection: severe diaarhea,
genital/anal pruritus, increase fever, and change
of oral mucosa.
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Route and Dosage IndicationsADULTS
Epilepsy: Starting dose is300 mg PO tid, then titrated up
as needed. Maintenance: 9001,800 mg/day PO in divideddoses tid PO; maximum intervalbetween doses should notexceed 12 hr. Up to 2,4003,600 mg/day has been used.Postherpetic neuralgia: Initialdose of 300 mg/day PO;300 mg bid PO on day 2;300 mg tid PO on day 3.
Adjunctive therapy in thetreatment of partial seizureswith and without secondary
generalization in adults andchildren 312 yr with epilepsyOrphan drug use: Treatment ofamyotrophic lateral sclerosisManagementof postherpeticneuralgia or pain in the areaaffected by herpes zoster afterthe disease has been treatedUnlabeled uses:Tremors ofMS, neuropathic pain, bipolardisorder, migraine prophylaxis
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Action Contraindications
Mechanism of actionnot understood;
antiepileptic activity
may be related to its
ability to inhibitpolysynaptic
responses and block
posttetanic
potentiation.
Contraindicated with
hypersensitivityto gabapentin.
Use cautiously
with pregnancy,
lactation.
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Adverse Effects Interaction
CNS: Dizziness,
insomnia, nervousness, fatigue, somnolence,ataxia, diplopia, tremor
Dermatologic: Pruritus,
abrasionGI: Dyspepsia, vomiting,nausea, constipation, drymouthReapiratory: Rhinitis, pharyngitis
Other: Weight gain, facialedema, cancer,impotence
Drug-drugDecreased
serum levels with
antacids
Drug-lab testFalse positives
may occur
with Ames N-
Multistix
SG dipstick test
for protein in the
urine
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AssessmentHistory:
Physical:
Interventions
http://nurseslabs.com/tag/assessment/http://nurseslabs.com/tag/history/http://nurseslabs.com/tag/interventions/http://nurseslabs.com/tag/interventions/http://nurseslabs.com/tag/history/http://nurseslabs.com/tag/assessment/ -
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Route and Dosage IndicationsAdults
100 mg PO bid taken atleast 30 min before or 2
hours after breakfast anddinner. Response may notbe noted for 2-4 wk andmay take up to 12 wk.
Periatric PatientsSafety and Efficacy not
establised
Reduction of symptomsof intermittentclaudication allowingincreased walkingdistance.
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Action Contraindications
Reversibly inhibits platelet
aggregation induced by avariety of stimuli includingADP, thrombin, collagen,shear stress, epinephrine,and arachidonic acid by
inhibiting cAMPphosphodiasterase III;produces vasculardilatation in vascular beds
with a specificity forfemoral beds; seems tohave no effect on renalarteries.
Contraindicated withallergy to cilostazol,
heart failure of any
severity, active
bleeding, hemostaticdisorders.
Use cautiously with
pregnancy, lactation,
renal dysfunction
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Route and Dosage Indications
OphthalmicBacterial orfungal conjunctivitis, blepharitis, keratitis.
and other infective eye conditionsAdult: As a 1% ocular ointment: Apply 4-5times daily.Topical/CutaneousPrevention and treatment of infection insevere burns
Adult: Apply a 1% cream onto affectedarea.
Bacterial orfungal conjunctivitis, blepharitis, keratitis.
Prevention and treatment ofsevere burns.
http://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Topical%20Antibioticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Eye%20Anti-Infectives%20&%20Antisepticshttp://www.mims.com/USA/drug/search/Topical%20Antibiotics -
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Action Contraindications
Silver sulfadiazine has broad
antimicrobial activity; it isactive against gram-positiveand gram-negative bacteria aswell as some yeasts and fungi.The silver salt acts mainly on
the cell wall and membrane todisrupt its intergrity thusallowing it to impair theessential enzymes, bacterialDNA and RNA leading to celldeath.Absorption: Slowly releasessulfadiazine when it comes intocontact with wound exudates.Up to 10% of sulfadiazine maybe absorbed.
Hypersensitivity to
sulphonamides; porphyria;premature infants and infants
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Route and Dosage Indications
General guidelines, 0.5-1U/kg/dy.The number ang size of daily doses,times of administration, and type ofinsulin preparation are determinedafter close medical screening ofthe patients blood and urine
glucose, diet, exercise andintercurrent infections and otherstresses. Usually givensubcutaneously. Insulin injectionconcentrated may be givensubcutaneously or IM but do notadminister IV.Adults with type 2 DM requiringbasal insulin 10U/day. Range,2-100U/day or 0.1-0.2 U/kgsubcutaneously in the evening or
10 U one or twice a day
Tx of type 1 DmTx of type 2 DM that cannotcontrolled by diet or oral drugsTx of hypokalemia with infusion ofglucose to produce shift of K+ intocells.Highly purified and human insulinspromoted for short courses oftherapy, newly diagnosed pts., pts.With poor metabolic control, andpts. With GD.
Action Contraindications
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Action Contraindications
Insulin is a hormone
secreted by beta cells ofthe pancreas that, byreceptor-mediated effects,promotes the storage of
the bodys fuels,facilitating the transport ofmetabolites and ions(potassium) through cellmembranes and
stimulating the synthesis ofglycogen from glucose, offats from lipids, andproteins from amino acids.
Contraindicated with
allergy to pork products;history of smoking or lung
disease (inhaled insulin)
Use cautiously with
pregnancy (keep patients
under close supervision; rigidcontrol is desired; following
delivery ,requirements may
drop for 24-72 hr, rising to
normal levels during next 6
week); lactation(monitormother carefully; insulin
requirements may decrease
during lactation)
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Oral, suppositories
CNS: Headache, dizziness, somnolence, insomia
Dermatologic: Rash
GI:Nausea, dyspepsia, constipation, GI bleed
IV preparation
GI: vomiting, GI bleeding
Hematologic: Increased bleeding problems
Respiratory: apnea, exacerbation of pulmonary
infection
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Ensure uniform dispersion of Insulin suspensions by rolling the vialbetween hands; avoid vigorous shaking.
Give maintenance doses subcutaneously, rotating injection sites
regularly to decrease incidence of lipodystrophy; give regular
insulin IV or IM in severe ketoacidosis or diabetc coma
Monitor patients receiving insulin IV carefully; plastic IV infusion
sets to have been reported to remove 20-80 % of the insulin;
dosage delivered to the patient will vary.
Do not give insulin injection concentrated IV; severe
anaphylactic reactions can occur.
Monitor urine or serum glucose levels frequently to determine
effectiveness of drug and dosage.
Inform patient to avoid alcohol; serious reactions can occur.
Inform patient to report ferver, sore throat, vomiting,
hypoglycemic reactions, rash
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Assessment Diagnosis Planning Interventions Rationale Evaluation
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Subjectivedata:The patientverbalized
Nagkadakoman ni akong
samad, walanay ayu-ayo
Objectivedata:Destruction ofskin layers at
the left andright foot notedNon-healingwound at leftfoot 100mm inlength; 80mmin width ; depth1mm notedNon-healingwound at rightfoot 20mm indiameter;depth 0.5mmPurulentdischarge
(-) pain pitting edema
Impaired skinintegrity :delayedwound
healingrelated toimpairedproteinsynthesis,decreasedtissueperfusion
After 2 hrs of
nusing
intervention, theclient will be able
to:
a. Verbalize
understanding of condition
and causative
factors.
b. Participate inprevention
and measure
of furtherinfections
c. Identify
interventions
appropriatefor condition.
Place client in
semi- to high
fowlers position.
Promote physical
and emotional rest
Encourage to
maintain lifestylechanges, such as
smoking and
alcohol cessation
Admiistered
medication to
reduce furtherinfection according
to physicians order
Perform anddiscuss proper ways
in wound dressing,
dry feet thoroughly
afterTeach client the
measures to prevent
further infection by
maintaining thewound covered
every after wound
dressing
-- To maintain
adequate
systemic tissueperfusion
-- Smoking
causes anincrease in
mucuos
production
and impairsciliary function
-- To reduce
risk for further
infection
Goal is Met,
After 2 hrs of
nusingintervention,
the client was
able to
verbalizeunderstanding
condition and
its causative
factors;participated in
measures to
avoidprevention;
and was able
to identify
interventionsappropriate
for condition
Assessment Diagnosis Planning Interventions Rationale Evaluation
S bj ti Aft 2 h f Assess for signs To Goal is Met
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SubjectiveData:The patientverbalizedmaglipong-
lipong man kousahay labawnag udto
ObjectiveData:Grade 2pitting edema
notedWeak, rapidpulse notedPR- 122bpmSerum sodiumlevel is 132mmol/L noted
Urine specificgravity is 1.030noted
Altered fluid
and
electrolyte
balance:
hyponatremi
a related to
excessive
sodium loss
After 2 hrs ofnursingintervention, theclient will be ableto:
a. Verbalizeunderstanding of causativefactors andpurpose oftherapeuticinterventions
b. Demonstratebehaviors tomonitor andcorrectdeficit, asindicated
Assess for signs
and symptoms of
hyponatremia:
- nausea- vomiting
- abdominal
cramps- weakness
- lethargy
- confusion
- seizure
Monitor serumelectrolyte results
Minimize clients
exposure toemotional and
physiological
stress
Advise pt. To eat
egg white per
meal
-- To
determine the
degree of
electrolytedeficiency
-- Stress
causes anincreased
output of
epinephrine,
norepinephrine, glucagon,
cortisol, all of
which
increasesblood sugar
-- egg white
contains
proteinalbumin which
increases
osmotic
pressure
Goal is Met,
After 2 hrs of
nursing
intervention,the client was
able to:
Verbalizeunderstanding
of causative
factors and
purpose of
therapeuticregimen
Maintained
eatingpatterns to
promote an
increase
inosmoticpressure and
in decreasing
blood sugar
levels.
Assessment Diagnosis Planning Interventions Rationale Evaluation
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Subjective:
The patient
verbalized
Paliya ra
akongkaunon
walay kan-
on
Kapoy man
ilihok
Objective:
Muscle
wasting
noted
Weakness
and fatigue
notedSerum
albumin is
2.65 g/dL
Hct0.26/L;
Hgb- 84
noted
Imbalanced
nutrition: less
than body
requirements
related tomuscle
weakness
secondary to
insulin
deficiency
After 3 hrs ofnursingintervention, theclient will beable to:a. Verbalize
understanding ofcausativefactors whenknownnecessary
interventions.b. Demonstrate
behaviors,lifestylechanges toregimen andmaintainappropriateweight
Assess the clientfor signs and
symptoms of
malnutrition:
- abnormal
BUN- low serum
albumin
- low hct, hgb,cholesterol and
lymphocte levels
Monitor bloodglucose levels
Advise patient to
eat at least 1cup
of rice with egg
white per meal
-- To determinedegree of
condition
-- To determinethe diet
needed to beingested
-- To reduce
muscle wasting
and to promote
tissue growthand wound
healing .
Goal is met,After 3 hrs of
nursing
intervention,
the client was
able to: Verbalize
understanding
of causativefactors
Change and
maintaineddiet as
advised.
Assessment Diagnosis Planning Interventions
Rationale Evaluation
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Subjective:The patientverbalized dilinaman ko
kaklaro saakong panan-aw, sumbolman ang dapitsa wala
Objective: Presence of
white patchcovering thelens of the lefteye notedAks someoneto read areadingmaterial ;blurred visionnoted
Sensoryperceptualalteration:visual related
to lenschanges
After 2 hrs ofnursingintervention, theclient will be
able to:a. Recognizeandcompensatefor sensoryimpairment
b. Identify/modify
externalfactors thatcontribute toalterations insensory/perceptualabilities
Assess thevisual acuity
Perform
actions topreventhyperglycemia-dietmodification- emotionalandpsychological
stress reduction
Informed theclient aboutthe diseaseprocess whichcontibute tothe condition Minimizediscussion ofnegativeswithin clients
vison
-- To determinthe degree ofcondition.-Maintenance
of blood sugarat a stable,near-normallevel hasbeen shownto reducesmal vesseland nerve
involvementand preventfurthermetaboliccataract devt- For the clientto understandthe presenceof such andmanage self
-- Client maymisinterpretand believereferences are
to himself
Goal is met,After 2 hours of
nursing
intervention,
the cliet was
able to :-- recognize
and
compensatefor sensory
impairment by
diet odificationand reduction
of stress
--Identify andmodified
external factors
that
contributed toalterations in
sensory ability
Assessment Diagnosis Planning Interventions Rationale Evaluation
Subjective data: Ineffective After 6 hours of Provide an Recognizing Goal is partially
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Subjective data:
The ptatient
verbalized ako
nay mosunodsa akong mga
maguwang
ane
Objective data:
Deficit in
participating
anddemonstrating
necessary
interventionsnoted
Anxiety noted
Alteration in
socialparticipation
Destructive
behavior
towards selfInability to
meet basic
needs
Ineffective
individual
coping related
to fear ofcomplications
and ability to
manage them
After 6 hours of
nursing
intervention, the
client will beable to:
a. Identify
effectiveand
ineffective
coping
patterns
b. Verbalizesense of
control
c. Reportdecrease in
negative
feelings
d. Modifylifestyle as
needed
e. Willing to
participatein treatment
plan and
sel-care
activities.
Provide an
atmosphere of
acceptance
Provide factual
information
concerning the
diagnosis,treatment, and
prognosis
Explore with his
previousmethods of
dealing with life
problems
Encourage
verbalization of
feelings,perceptions, and
fears
-- Recognizing
problemsand
sharing feelings
is best broughtabout in an
atmospere of
warmth andtrust
--Factual
information
serves as a
foundation toexplore
feelings and
alternativecoping
strategies
--Present and
past copingstatus assists
the pt and his
support system
on successfulmethods.
-- open,
nonthreatening
discussionsfacilitate the
identification of
causative and
contributingfactors.
Goal is partially
met,
The client was
able to:--Modify lifestyle
as needed yet
wasnt able toverbalize sense
of control in the
situation and
presence of
condition
Observe thedegree of familysupport
--Assessingfamilyinteraction
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pp
Discuss with
concerned
others how they
can help
serves as a basis
for identifying
patients supportsystems or lack
thereof.
-- Family and
friends are often
willing but
unsure how tohelp . Identifying
specific
strategies such
as praise andencouragement
will promote
acceptance of
change.