A B. Breast Case-Control Analysis CaseControl PC20.013659 X-sq=10.7, df=1, p=0.001 OR=2.9 (1.6-5.5),...
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Transcript of A B. Breast Case-Control Analysis CaseControl PC20.013659 X-sq=10.7, df=1, p=0.001 OR=2.9 (1.6-5.5),...
A
B
Breast Case-Control Analysis
Case ControlPC2<0.01 50 28PC2>0.01 36 59
X-sq=10.7, df=1, p=0.001 OR=2.9 (1.6-5.5), p=0.00076
A B
C D
E FGO Terms - Survival
PDGF signaling pathway (+)T cell activation (+)B cell activation (+)Angiogenesis (+)FDR p<0.0001FDR p = 0.0001 - 0.001FDR p = 0.001 - 0.01FDR p = 0.01 - 0.05
GO Terms - Riskimmune response (-)response to stimulus (-)cell-cell adhesion (+)immune system process (-)macrophage activation (-)FDR p = 0.001 - 0.01FDR p = 0.01 - 0.05FDR p = 0.05 - 0.20 (p<0.01)
Colon Case-Control AnalysisA
C
Case ControlPC2<0.01 57 50PC2>0.01 38 45 X-squared = 0.8, df = 1, p-value =0.38
OR=1.3 (0.75-2.4), p=0.38
GO Terms - SurvivalAngiogenesis (+)p53 pathway by glucose deprivationPDGF signaling pathwayIntegrin signalling pathwayN-acetylglucosamine metabolismFDR p<0.0001FDR p = 0.0001 - 0.001FDR p = 0.001 - 0.01FDR p = 0.01 - 0.05FDR p > 0.05 (p<0.01)
B
D
P=0.007
P=0.040 P=0.265
P=0.149P=0.047
P=0.012
P=0.027
P=0.404
P=0.006
Breast Cancer EWAS Colon Cancer EWAS Pyrosequencing
P=0.002
P=0.018
P=5.66e-4
P=3.76e-5
P=0.009
P=1.97e-5
Colon Cancer EWASTime Since Quitting
Colon Cancer EWASLength of Time Smoking
A B C
Never Former Current Never Former Current
D E F
Never Former Current Never Former Current Never Former Current
Breast Cancer EWAS Colon Cancer EWAS Pyrosequencing