9.4 Notes ID, Collection of Evidence. Objectives Describe the laboratory tests normally used to...
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![Page 1: 9.4 Notes ID, Collection of Evidence. Objectives Describe the laboratory tests normally used to perform a routine drug identification analysis Understand.](https://reader035.fdocuments.net/reader035/viewer/2022062620/551abe78550346856e8b5653/html5/thumbnails/1.jpg)
9.4 Notes
ID, Collection of Evidence
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Objectives
Describe the laboratory tests normally used to perform a routine drug identification analysis
Understand proper collection and preservation of drug evidence
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Drug Identification
Either a specimen is a specific drug or it is not
Chemists must be prepared to support and defend the validity of the results in a court of law Screening test – reduces possibilities
first test is color test Confirmation test - pinpointing
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Drug Identification cont.
The procedures must be able to confirm that the likelihood of any other substance responding in an identical manner to a certain drug is so minimal that there exists no other conclusion but reasonable scientific certainty
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Analytical schemes
1. Color tests
2. Microcrystalline tests
3. Chromatography
4. Spectrophotometry
5. Mass Spectrometry
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Color Tests1. Marquis reagent – purple with heroine and morphine; orange with amphetamines
2. Dillie-Koppanyi – violet blue with barbiturates
3. Duquenois-Levine – ABC layers with layer C purple with marijuana
4. Van Urk – purple/blue with LSD
5. Scott Test – ABC (A with cocaine, blue to pink in B, and blue again in C layer)
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Microcrystalline Tests Chemical reagent added to drug on slide Crystalline precipitate with unique structures results
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Chromatography Uses TLC (Thin Layer Chromatography) and gas Requires the Rf comparison of known and questioned drugs Accompanies color and crystal test
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Spectrophotometry Absorption of light in the UV and IR regions of the spectrum Establishes probable drug IR can specifically ID a substance
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Mass Spectrometry GC/MS Utilizes the fragmentation pattern of sample molecules which serves as a fingerprint Can be used to separate components of a complex drug mix
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ID of Marijuana Based on botanical features Cystolithic hairs – short hairs, shaped like bear claws DuQuenois-Levine color test Without leaf, TLC is used
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Collection & Preservation of Drug Evidence
Original container Airtight container if glue sniffing Packages marked Background information