7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of...
-
Upload
thomas-crawford -
Category
Documents
-
view
216 -
download
0
Transcript of 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of...
![Page 1: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/1.jpg)
7.5Proteins
![Page 2: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/2.jpg)
7.5.1 Explain the four levels of protein structure, indicating the significance of each level.
1°- sequence of amino acids in the chain
2°- coils; H bonds; collagen, keratin have repeated sequences so have lots coils
α-helix: hair, wool, horns, feathers
β-pleated sheet: silk
![Page 3: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/3.jpg)
7.5.1 Explain the four levels of protein structure, indicating the significance of each level.
3°- helix folding; R groups interact: hydrophobics cluster together on inside, hydrophilics cluster on outside,
disulfide bridges between S of 2 R groups (cov bond),
ions may be cofactors
![Page 4: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/4.jpg)
7.5.1 Explain the four levels of protein structure, indicating the significance of each level.
4°- different polypeptides combine w/H bonds, +/- attractions, hydrophobic forces, and/or disulfide bridges;
common in large globular proteins (hemoglobin—2 α chains, 2 β chains)
“conjugated proteins” - binding of prosthetic group: each chain also has a Heme group, contains Fe (not a polypeptide)
chlorophyll, electron transport chain enzymes are other examples
![Page 5: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/5.jpg)
7.5.2 Outline the difference between fibrous proteins & globular proteins,
with reference to two examples of each protein type.
Fibrous Globular
Shape Long Tightly folded
Solubility Insoluble in water Soluble in water
Main level of organization
2° is most important 3° is most important
Function Structural (they ARE something)
Functional (they DO something)
Examples Collagen, keratin, myosin
Hemoglobin, enzymes, antibodies, hormones
![Page 6: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/6.jpg)
7.5.3 Explain the significance of polar and non-polar amino acids.
• 20 common amino acids• 8 w/non-polar R groups
– Insoluble in water– Cluster together @ center (4° structure)
• More non-polar AAs less soluble in water• Cell membrane (phospholipid bilayer): polar on
outside, non on inside – Protein situated with hydrophilic portions to outside of
membrane, hydrophobic sections to center
![Page 7: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/7.jpg)
7.5.4 State four functions of proteins, giving a named example of each:
• Structure: collagen (fibrous, structural ptn) builds tendons & in skin
• Enzymes: all are globular – starch –amylase maltose
• Transport: hemoglobin (globular, conjugated); readily, reversibly binds Oxygen b/c of heme group
![Page 8: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/8.jpg)
7.5.4 State four functions of proteins, giving a named example of each:
• Hormones: some are ptns (some are steroids)– Insulin
• Contractile: muscle contractions (actin, myosin)
• Defense: antibodies/immunoglobulins for defense against antigens
![Page 9: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/9.jpg)
![Page 10: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/10.jpg)
![Page 11: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/11.jpg)
![Page 12: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/12.jpg)
![Page 13: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/13.jpg)
![Page 14: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/14.jpg)
![Page 15: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/15.jpg)
![Page 16: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/16.jpg)
![Page 17: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/17.jpg)
![Page 18: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/18.jpg)
![Page 19: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/19.jpg)
![Page 20: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/20.jpg)
![Page 21: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/21.jpg)
![Page 22: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/22.jpg)
![Page 23: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/23.jpg)
![Page 24: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/24.jpg)
![Page 25: 7.5 Proteins. 7.5.1 Explain the four levels of protein structure, indicating the significance of each level. 1°- sequence of amino acids in the chain.](https://reader035.fdocuments.net/reader035/viewer/2022062511/55142f74550346d8488b5ee2/html5/thumbnails/25.jpg)