ROYAL CONTINENTAL HOTEL Via Partenope 38/44

7TH INTERNATIONAL CONFERENCE ON THORACIC ONCOLOGY

NAPLES, June 20TH - 22ND 2019

PROGRAMME

AIOT Board

Fortunato CiardielloFilippo de MarinisCesare GridelliRossella Spinetti

Lucio CrinòMarina Chiara Garassino

Nicola Normanno Lorenzo Spaggiari

Fortunato Ciardiello

SCIENTIFIC & ORGANIZING COMMITTEE

AIOT & CIOT PRESIDENT

Cesare Gridelli & Nicola Normanno

CONFERENCE CO-PRESIDENTS

WELCOME FROM THE PRESIDENTUnder the auspices of

Dear Collegue,

it’s my great pleasure to invite you to partecipate in theproceedings of 7th Italian Conference on ThoracicOncology (CIOT) that, in its annual recurrence, takesplace in Naples from June 20th to June 22nd 2019organized by AIOT (Italian Association of ThoracicOncology) and that I’ve the responsibility to chair.

I would like to call your attention to at least threeinteresting aspects of Milan’s Conference that make theappointment very peculiar and that I identify in itsInternational form, in the location and in its goals.

International formThe 70% of Faculty is composed of foreign

speakers, everybody playing an active part in clinicalresearch in Thoracic Oncology and KOL in theirrespective countries. We expect significant foreigndelegations. The official language of the Conferencewill be English.

LocationLocated in a wonderful position, in the heart of

Naples, the conference venue offers to the city ameeting point of extraordinary importance. Its naturalelegance and flexibility make it the ideal location forcongresses, meetings and events of any kind.The location is in the heart of history and Naples keyattractions.

GoalsSetted immediately after ASCO, the Conference

gives an update on the data coming from ClinicalResearch in Thoracic Oncology directly from the voiceof its Authors more representative in an appointmentthat we would like to be lasting inside of the internationaltrack.

For these reasons I’m trusting that you shouldappreciate the effort of the organizing secretariat torealize this scientific meeting doing credit to us withyour attendance in Naples.

Arrivederci

President of 7th CIOTFiortunato Ciardiello

CONFERENCE VENUE

Royal Continental Hotel Via Partenope 38/44, NapoliTel. (+39) 081 245 2068

The Royal Continental is located on the Napleswaterfront and offers an ideal location with superbviewers of the gulf and Posillipo hillside. It is about 500metres from the famous shopping area and from themain cultural area of the city.The meeting takes place in the Auditorium located atthe ground floor of the Royal Continental Hotel.

HOTEL ACCOMMODATIONOrganizing secretariat SOS Scientific Organizing ServiceS.r.l. (rossella.spinetti@alice.it), is at your disposal for anyinformation about hotel reservations.

GENERAL INFORMATION

PARKING FACILITIESThe indoor car parking, located aside the Hotel, is atdisposal of all the delegates at their charge;

SECRETARIAT AND REGISTRATION DESKSThe pre-registration and on site registration desks areat the disposal of participants as follow:

Thursday, June 20 - 12.00/19.300 hrs Friday, June 21 - 08.00/19.00 hrsSaturday, June 22 - 08.00/13.30 hrs

At the secretariat desk are available the followingservices:• On site registration (cash, cheques)• Pre-registrations A - L• Pre-registrations M - Z• Faculty registration • CME credits desk

CLOAKROOMIt is at disposal of all the guests free of charge.Delegates are kindly requested not to leave theirpersonal belongings after the closing time.

BARLocated in the Conference area it is at the disposal ofthe participants at their charge.

INSURANCEConference organizers cannot accept liability forpersonal injuries or for loss of or damage to propertybelonging to congress participants, either during or asa result of the Conference.

CLIMATEJune weather in Naples is generally sunny and warm.The temperature often rises during the day at anaverage of 25°. Light summer clothing is mostsuitable. Rain is also possible; light raincoat andsomething warm for the evening are advisable

CURRENCYThe official currency in Italy is the Euro (€).

TIPPINGService is usually included in the bill in bars andrestaurants but tips are welcome.

BANKBanks are open from Monday to Friday from 08.30 to13.30 hrs and from 15.00 to 16.00 hrs. Banks areclosed on Saturday and Sunday. Many banks haveautomatic currency exchange machines that also takecredit cards.Most hotels, restaurants and shops accept foreigncurrency and major credit cards.

ELECTRICITYVoltage is 220V AC, 50Hz. Plugs have two or threeround pins. Foreign voltage could require and adapter.

PRACTICAL INFORMATION

All fees are requested in Euros.It’s possible to register individually by visiting AIOTwebsite www.oncologiatoracica.it in the propersection following the instructions.

WHAT IS COVERED BY THE FEE?The registration fee includes an unlimited access to allscientific sessions, a full set of congress material andlunch on Friday June 21.

ADMISSIONName badges will be used as passes. All participantsand official guests are kindly requested to wear theirname badge during the Meeting activities and socialevents. The badge allows the entrance to the scientificsessions and lunch.

REGISTRATION FEES

ATTRACTIONS

NAPLES

NAPLES KEY ATTRACTIONS

1. Spaccanapoli 4. Napoli Sotterranea

2. Palazzo Reale& Museo di Capodimonte

5. Quartieri Spagnoli

3. Piazza del Plebiscito6. Rione Sanità

7. Santa Chiara

8. Maschio Angioino

9. Cristo Velato

1

6

4

2

7

5

3

8

9

SCIENTIFIC INFORMATION

MAIN SCIENTIFIC PROGRAMME OUTLINEThe scientific programme covers three days (ThursdayJune 20, Friday June 21 and Saturday June 22, 2019)and consists of State-of-the-Art Lectures, MainLectures, Debates and Face to Face sessions.

The “Debate” sessions are about controversial topicsin thoracic oncology; the “Face to Face” sessionsinstead go on vexed questions and they deal with twospeakers and to add requests from some “shooters”put in charge in order to stimulate the audience for alively discussion.

WEBSITEVirtual Meeting of the Conference will be availableafter the end of the Meeting on AIOT official websitewww.oncologiatoracica.it.

ITALIAN MINISTRY OF HEALTH - CME CREDITS The accreditation has been asked for entirely meeting.To obtain Italian credits the delegates must attend inthe 90% percentage of the time sessions. Anelectronic device is arranged.

At the moment of registration each participant will receivethe evaluation forms and learning questionnaire of thescientific sessions. These forms and questionnairemust be filled in and return to the “CME credits” desk. Electronic tags are used to record the CME credits.

The electronic readers are placed just outside the“Auditorium”. It is sufficient to pass through theelectronic device to have the credits recorded.

To obtain credits, Italian participants have to:

• record both the entrance and the exit of eachMeeting day

• return the electronic tag to the Organizing Secretariatat the end of the Conference

• return the evaluation forms and questionnaire dulyfilled into the “CME credits” desk. The anagraphicaldata must compulsorily be indicated since requiredby the Italian Ministry of Health

Please note that if you loose or fail the tag, you will

be charged € 10,00 by the Organizing Secretariat.

FACULTYGuidelines for Speakers and Chairs

For Chairs:

• Locate your session Room in due time

• Be in the Room assigned for presentation at least 10minutes before the beginning of the session

• Respect the timing allowed to the session and eachpresentation

• All presentations, discussions and questions are inEnglish

For Speakers:

• Follow the instructions indicated at the paragraph“Audiovisual Instructions”

• Locate your session Room in due time

• Be in the Room assigned for presentation at least 10minutes before the beginning of the session to meetthe Chairs

• Respect the timing allowed for your presentation

• All presentations, discussions and questions are inEnglish

AUDIOVISUAL INSTRUCTIONSA multimedial projection centre will be at the disposalof the Speakers at the ground floor of the RoyalContinental Hotel aside the Auditorium.

ONLY PC DATA PROJECTION ARE AVAILABLE AT

THE CONFERENCE

The “Auditorium” is provided with the laptop.Use of one’s laptop is not allowed.

Should Speakers have their personal laptop, a CDRom or a USB key, they are kindly requested to go tothe multimedial projection centre to have theirpresentation copied. The presentation will be thenforwarded through a LAN network from multimedialprojection centre directly to the computer in thepresentation room.

We recommend to contact the multimedial projectioncentre the day before your presentation. At any rate,presentation material must be available:

• 45 minutes before for Power Point presentation onCD Rom or USB key

• 1 hour before for presentation on Personal Computer

CERTIFICATE OF ATTENDANCEAttendance certificates will be issued on request to allregularly registered participants at the SecretariatDesk at the end of the meeting.

FACULTY GUIDELINES

June 20th, 2019 THURSDAY

WELCOME

Fortunato Ciardiello (Naples, I)Cesare Gridelli (Avellino, I)Nicola Normanno (Naples, I)

14.30 OPENING LECTURE

Introduction: Fortunato Ciardiello (Naples, I)

THE NEW FRONTIERS OF IMMUNO-ONCOLOGYAND PRECISION MEDICINESolange Peters (Lausanne, CH)

15.00-16.00 SCIENTIFIC SESSIONEARLY STAGES/LOCALLY ADVANCED NSCLC: FROM BENCH TO BEDSIDE

Chair: Lorenzo Spaggiari (Milan, I)

. Adjuvant/neoadjuvant immunotherapyPatrick Forde (Baltimore, USA)

. The role of immunotherapy in stage IIIJavier De Castro (Madrid, E)

Discussion

PROGRAMME

16.00-16.30 LECTURE

Introduction: Cesare Gridelli (Avellino, I)

THE NEW OPTION OF IMMUNOTHERAPY IN SCLCStephen V. Liu (Washington, USA)

16.30-17.30 FACE TO FACEBRAIN METS TREATMENT IN ONCOGENE ADDICTED NSCLC

Chair: Lucio Crinò (Meldola, I) . Radiotherapy Paolo Muto (Naples, I)

. Targeted TherapyPatrick Forde (Baltimore, USA)

Discussion

17.30-18.30 SCIENTIFIC SESSION Unrestricted grant

THE EARLIER THE BETTER: THE IMPORTANCE OF MDT IN NSCLCPATIENTS’ MANAGEMENT - A paradigm change in stage III andEGFRm+ stage IV lung cancer

Coordina Filippo de Marinis (Milano, I)

. EGFR Federico Cappuzzo (Ravenna, I)

. Selezione del paziente Nicola Normanno (Napoli, I)

. Il ruolo del radioterapista Filippo Alongi (Verona, I)

. Il ruolo dell’oncologo Filippo de Marinis (Milano, I)

June 21st, 2018 FRIDAY

09.45-10.30 LECTURE Unrestricted grant

RAISE THE BAR NEL NSCLC ALK/ROS1: IL RUOLO DI CRIZOTINIBMarina Chiara Garassino (Milano, I)

10.30-11.30 SPECIAL SYMPOSIUMIMMUNO-IMMUNO COMBO

Chair: Marina Chiara Garassino (Milan, I)

. Nivolumab+ipilimumab: reality and hopes beyond TMBVassiliki Papadimitrakopoulou (Houston, USA)

. Durvalumab+tremelimumabManuel Cobo (Malaga, E)

Discussion

11.30-13.00 ARENACOMBO CHEMO-IMMUNO 1ST LINE: THE BEST CHOICES

Chairs: Filippo de Marinis (Milan, I), Cesare Gridelli (Avellino, I)

. Chemo+pembrolizumab Luis Paz Ares (Madrid, E)

. Chemo+atezolizumabEnriqueta Felip (Barcelona, E)

. Chemo+nivolumabJavier De Castro (Madrid, E)

Discussion

13.00-14.00 Lunch

14.00-14.30 LECTURETHE EMERGING ROLE OF NGS-BASED LIQUID BIOPSY IN NSCLC

Nicola Normanno (Naples, I)

14.30-15.30 SCIENTIFIC SESSIONTHE OPTIMAL SEQUENCING IN PATIENTS WITH ONCOGENE ADDICTION

Chair: Filippo de Marinis (Milan, I)

. EGFRShirish Gadgeel (Detroit, USA)

. ALKStephen V. Liu (Washington, USA)

Discussion

15.30-16.30 FACE TO FACE1-LINE TREATMENT A-NSCLC PD-L1 50%:IMMUNO vs IMMUNO-CHEMO COMBO

Chair: Cesare Gridelli (Avellino, I) . Pro immunoEnriqueta Felip (Barcelona, E)

. Pro chemo-immuno comboVassiliki Papadimitrakopoulou (Houston, USA)

Discussion

16.30-17.30 SCIENTIFIC SESSION Unrestricted grant

HOW IMMUNOTHERAPY IS REVOLUTIONING LUNG CANCER CARE:INTERACTIVE DISCUSSION ON MAIN EVIDENCES AND THEIRIMPACT ON CLINICAL PRACTICE

Coordinano Filippo de Marinis (Milano, I) & Cesare Gridelli (Avellino, I)

Intervengono Emilio Bria (Roma, I) & Alessandro Morabito (Napoli, I)

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June 22nd, 2018 SATURDAY

08.45- 09.30 LECTURE Unrestricted grant

L’ISOLA DI ALK: UN RIFUGIO NEL DESERTO DELLA MALATTIAONCOLOGICA POLMONAREFilippo de Marinis (Milano, I)

09.30-10.00 LECTURE

Introduction: Lucio Crinò (Meldola, I)

ACTIONABLE BIOMARKERS IN NSCLC BESIDES EGFR/ALKFabrice Barlesi (Marseille, F)

10.00-11.00 SCIENTIFIC SESSIONIMMUNOTHERAPY IN PREVIOUSLY TREATED NSCLC

Chair: Nicola Normanno (Naples, I) . PD-1 InhibitorsLuis Paz Ares (Madrid, E)

. PD-L1 InhibitorsFabrice Barlesi (Marseille, F)

Discussion

11.00-12.45 SPECIAL SYMPOSIUMIMMUNOTHERAPY MANAGEMENT EMERGING PROBLEMS

Chair: Marina Chiara Garassino (Milan, I)

. HyperprogressionChristophe Le Tourneau (Paris, F)

. Ir Pneumonitis Jerome Le Pavec (Paris, F)

. Resistance mechanisms to immunotherapyShirish Gadgeel (Detroit, USA)

Discussion

12.45 CLOSING REMARKS

Fortunato Ciardiello, Cesare Gridelli, Nicola Normanno

SPONSORSHIP LEVELS

OTHER SPONSOR

BRONZE SPONSOR

PLATINUM SPONSOR

GOLD SPONSOR

SCIENTIFIC  SECRETARIATAIOT - Associazione Italiana di Oncologia Toracica

Via Salaria, 237 - 00199 RomaTel. +(39) 333 65 93 541 - Fax (+39) 06 85 40 679

oncologiatoracica@yahoo.it - www.oncologiatoracica.it

ORGANIzING SECRETARIATSOS S.r.l.

Via Salaria, 237 - 00199 Roma Tel. (+39) 333 65 93 541 - Fax (+39) 06 85 40 679

www.scientificorganizingservice.com - rossella.spinetti@alice.it

THIS PROGRAMME AND REGISTRATION FORM ARE AVAILABLE ON AIOT WEBSITE

www.oncologiatoracica.it