65 Per Cent of Couples Successful by 6th Attempt at IVF_ Study _ CTV News
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Transcript of 65 Per Cent of Couples Successful by 6th Attempt at IVF_ Study _ CTV News
12/30/2015 65 per cent of couples successful by 6th attempt at IVF: study | CTV News
http://www.ctvnews.ca/health/65percentofcouplessuccessfulby6thattemptativfstudy1.2717972 1/2
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65 per cent of couples successful by 6th attempt at IVF: study
More than 65 percent of women have had a child via IVF by their sixth attempt, a study out of the UK. has found. ( Katarzyna Bialasiewicz / Istock.com)
Relaxnews Published Wednesday, December 30, 2015 8:43AM EST Last Updated Wednesday, December 30, 2015 8:53AM EST
A U.K. study recommends that couples undertaking IVF (In Vitro Fertilization) should have up to six attempts, rather than the 3 or 4 embryotransfers that is currently standard practice. By that stage, 65 per cent of women, with an average age of 35, have been able to have a baby.
This recent study, which was published in The Journal of the American Medical Association, could give fresh hope to couples who have tried tohave a child for several years via IVF. In practice, IVF is often stopped after three or four unsuccessful embryo transfers.
An IVF cycle includes treatment with hormones to stimulate the ovaries, egg retrieval and the transfer of embryos arising from that hormonalstimulation.
Professor Debbie Lawlor of the University of Bristol and Professor Scott Nelson of the University of Glasgowsuggest that the number of IVF cycles per patient should be extended beyond the usual three or four. Theirresearch shows that 65 per cent of women have a baby by the sixth attempt, taking an average of two years.
The researchers calculated the live birth rate for each cycle, as well as the cumulative probability ofachieving a live birth across multiple IVF cycles up to 9.
The study followed 156,947 patients (with an average age of 35, and a median fouryear duration ofinfertility) and 257,398 IVF ovarian stimulation cycles.
The researchers found that in all women, the live birth rate for the first cycle was 29.5 per cent, and 32 per cent for those under 40. The rateremained above 20 per cent up to and including the fourth cycle for women under 40. The cumulative live birth rate across all cycles continued toincrease until the ninth cycle. By the sixth cycle, 65.3 per cent of the women had a live birth, taking an average of 2 years.
Because of these encouraging results, the study's authors advise parentstobe to consider IVF as a process with multiple cycles, rather than asingle shot.
A test to predict the success rate of IVF is currently being developed by a team at France's Montpellier University Hospital in partnership withresearchers at the French institute Inserm. They are studying an IVF outcome biomarker: the cellfree DNA present in a woman's blood. With asimple blood test, it will be possible to know the best moment for fertilization, thereby increasing the chances of success. This test could be used inthe hospital from January 2016.
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12/30/2015 65 per cent of couples successful by 6th attempt at IVF: study | CTV News
http://www.ctvnews.ca/health/65percentofcouplessuccessfulby6thattemptativfstudy1.2717972 2/2
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