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Nature © Macmillan Publishers Ltd 1998
8
correspondence
Sir — The article by Wennerås and Wold(Nature 387, 341–343; 1997), containingclear proof of nepotism in a funding body,is fascinating.
I have had many discussions withcontemporaries and colleagues about the wayin which decisions are made by the major UKfunding bodies, and there is generalagreement that the system is seriously flawed.
Everyone has stories about autocraticcommittee chairmen with whom no onedares to disagree, referees with a studycompetitive to that of the applicant,committee members who take up ideas fortheir own groups a year or two after theoriginator’s application was turned down,and committees where more than half thegrants under discussion were awarded tomembers of the committee.
More recently, in Europe, I heard of twoEuropean Commission contracts awardedto a group that had been removed from itsown national register because of poorperformance and no publications. Ofcourse, no one has had, until recently (seeD. F. Horrobin, The Lancet 348, 1293–1295;1996), any good idea how the system mightbe changed to avoid lack of objectivity, biasand the unfair apportioning of huge sumsof money, often repeatedly.
I have been involved in making grantapplications to the major funding bodiessince the mid-1960s. In all that time, it wasuntil recently never necessary to object tofair or even relatively unfair criticism.However, I wrote last year to one of themajor funding bodies about the carelessway in which our application was bothrefereed and subsequently dealt with by thecommittee. It was not prompted by sourgrapes but by the indisputably incorrect
statements made in their letter of rejection.My letter was designed, first, to explain
how much more helpful it would be tothose of us ‘on the other side’ to receivefeedback before the committee meetingthat decides our scientific futures. Grantapplications are dealt with in this way by atleast one major UK funding body. Secondly,I wished to point out the extent to whichthe outcome can be substantially affected byluck and by objectivity (or lack of it) fromboth referees and committee members.
The unsatisfactory reply that I receivedcontained the comment: “You are free, ofcourse, to submit a fresh application if thatis substantially different from this one.”Given that the reasons for turning down theapplication could not be discussed, are weto play some sort of guessing game as tohow our “important study” (thecommittee’s words) should be redesigned?If I am to go by the referees’ reports, thenvery little needs to be altered. Am Itherefore to take a stab at suggestingsomething completely different which istrendy and of academic interest but maynot improve the welfare of patients to theextent that I believe our present protocolmay do?
This is a difficult and dispiritingsituation, which erodes research time,thinking time and confidence. It is notsurprising that nothing will induce manygraduate students (male or female) to takeup scientific research as a career these days.Linda M. CastellCellular Nutrition Research Group,University Department of Biochemistry,South Parks Road,Oxford OX1 3QU, UKe-mail: [email protected]
Sir — The research that Wennerås and Woldhave been able to do and therefore the issuesthey raise are crucially dependent on theSwedish commitment to freedom ofinformation. The findings, however, are ofrelevance to the global research community.
In the British case, our pathological loveof secrecy means that it is simply impossibleto monitor equity of treatment, either in theprocedures for the allocation of grants or inthe recognition of scientific excellence.Bodies from the research councils to theRoyal Society should find this study foodfor thought, as they, like the judiciary, areinstitutions where pale males have been fortoo long chosen to overrepresentthemselves for the health of either scienceor society.
For that matter, Nature’s innovatoryfootnote drawing attention to the gender ofthe three referees was itself both smug andsexist. A more worthy reaction would havebeen for Nature to concentrate first on thepossibility of a beam in its own eye. In thesame issue, your account of the “ScienceWars” (Nature 387, 331–335) manages toerase the fact that Gross and Levitt hadattacked, most vitriolically and extensively,the feminist critics of science. Indeed, as Irecall their book, the single most attackedperson was the distinguished USphilosopher of science Sandra Harding. Byfocusing exclusively on the fights betweenthe boys, Nature managed to make even the“Science Wars” another pale male story.
Is it any wonder that some of us thinkthat the tide is rather unlikely to turn?Hilary Rose4 Lloyd Square,London WC1X 9BA, UKe-mail: [email protected]
NATURE | VOL 387 | 26 JUNE 1997 841
Serious flaws in UK funding system
Cannibalism and kuruSir — In his review of Deadly Feasts:Tracking the Secrets of a Terrifying NewPlague (Nature 386, 565; 1997), RobertDesowitz repeats a fundamental error withregard to the aetiology of kuru. He writes:“Gajdusek and his Australian colleagues,Michael Alpers and Vincent Zigas, showedthat cannibalism was the cause of kuru. TheFore women and children, but not the men,ate — totally consumed — their deadrelatives.”
That cannibalism might be the route tokuru transmission was discovered by twoanthropologists, Shirley Lindenbaum andRobert Glasse, five years after Gajdusek firstarrived in the Eastern Highlands of PapuaNew Guinea, years in which every attemptto unravel the cause of kuru had failed. In
1961, they spent nine months with the Foresearching for a possible genetic cause forkuru. None existed.
Their second visit proved more fruitful.A New Zealand neurologist andepidemiologist, Dr R.W. Hornbrook,suggested that they try to answer thequestion “what is it that the adult womenand the children of both sexes in the Foretribe are doing that the adult men are not?”.
They found that the women, whoprepared the bodies for burial, occasionallyate part of the flesh and of the steamed braintissue. But far from their “totally consumingtheir dead relatives”, or cannibalism being aritual in the Fore tribe, it was a casualpractice that had infiltrated from tribes inthe south of the region within livingmemory. The Fore themselves said that “itwas after the first aeroplane flew over that
we tried cannibalism for the first time”.Back at the US National Institutes of
Health, Gajdusek and Joe Gibbs now triedto induce kuru in nonhuman primates byfeeding them with kuru-infected humanbrain. They failed to induce the disease,even when they inserted the infected tissuedirectly into the stomach through a gastrictube. So they believe that direct inoculationinto the bloodstream or through themucous membrane was the route ofinfection. Women and children with cutsand sores on their hands would frequentlyrub their eyes and noses when handlingdead bodies, so any infectious particlescould enter the body quite easily.June GoodfieldInternational Health & Biomedicine,The Manor House, Alfriston, East Sussex BN26 5SY, UK