5.2 Mitosis and Cytokinesis Chapter 5 Cell Growth and Division Mr. Shilala DAHS.
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Transcript of 5.2 Mitosis and Cytokinesis Chapter 5 Cell Growth and Division Mr. Shilala DAHS.
![Page 1: 5.2 Mitosis and Cytokinesis Chapter 5 Cell Growth and Division Mr. Shilala DAHS.](https://reader035.fdocuments.net/reader035/viewer/2022062314/56649e765503460f94b77b2d/html5/thumbnails/1.jpg)
5.2 Mitosis and CytokinesisChapter 5 Cell Growth and Division
Mr. Shilala
DAHS
![Page 2: 5.2 Mitosis and Cytokinesis Chapter 5 Cell Growth and Division Mr. Shilala DAHS.](https://reader035.fdocuments.net/reader035/viewer/2022062314/56649e765503460f94b77b2d/html5/thumbnails/2.jpg)
KEY CONCEPT Cells divide during mitosis and cytokinesis.
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DNA and Chromosomes• DNA is a double stranded molecule made of four
subunits called nucleotides• A chromosome is one long continuous thread of
DNA– Consists of numerous genes with regulatory information– Your cells have 46 chromosomes– If stretched out straight and laid end to end DNA in one cell would
be about 10 feet long
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Chromosomes condense at the start of mitosis.• DNA is loosely organized during interpahse
– Looks like spaghetti
• DNA wraps around proteins (histones) that condense (shrink) it.
• DNA plus proteins is called chromatin
DNA doublehelix
DNA andhistones Chromatin
SupercoiledDNA
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• Chromatid• One half of a duplicated
chromosome is a chromatid.• Sister chromatids (identical
chromatids) are held together at the centromere.
• Telomeres protect DNA and do not include genes.- Prevent chromosomes from
accidentally attaching to each other
Condensed, duplicated chromosome
chromatid
telomere
centromere
telomere
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Parent cell
centrioles
spindle fibers
centrosome
nucleus withDNA
• Interphase prepares the cell to divide.
• During interphase, the DNA, or chromosomes, are duplicated.
Mitosis and cytokinesis produce two genetically identical daughter cells.
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Mitosis• Mitosis divides the cell’s nucleus into 2
genetically identical nuclei in four stages– Each has full set of DNA
• IPMAT– Interphase
• Not part of mitosis
– Prophase – Metaphase– Anaphase– Telophase
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• Prophase– DNA and Proteins condense into Chromosomes – Nuclear membrane breaks down, centrioles
move to opposite poles and spindle fibers form
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• Metaphase– Chromosomes line up in the middle of the cell.– Spindle fibers attach to each chromosome
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• Anaphase– Sister chromatids separate to opposite sides of
the cell.
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• Telophase– New nuclei form– Chromosomes begin to uncoil – Spindle fibers fall apart.
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• Cytokinesis– Cytokinesis is the division
of the cytoplasm into two cells
– In animal cells, the membrane pinches closed.
– In plant cells, a cell plate forms