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Name the organ from which these slides were prepared.
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Pancreas
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Name the island of tissue at the center of each picture.
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Islet of Langerhans
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Name the cells located in the Islets of Langerhans
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Alpha cells, Beta cells, Delta cells
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What do the alpha cells produce?
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Glucagon
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What do the beta cells produce?
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Insulin
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What do the delta cells produce?
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Somatostatin
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What are these cells called ?
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Acinar cells
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Are acinar cells endocrine or exocrine in function?
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Exocrine
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What is the exocrine function of acinar cells?
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Acinar cells secrete digestive enzymes. Name a digestive
enzyme seceted?
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Trypsinogen and chymotrypsinogen
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What is the endocrine function of the pancreas?
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Secrete insulin, glucagon, and somatostatin
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Name the hormone that causes a decrease in plasma glucose.
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Insulin
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Name the hormone that causes an increase in plasma glucose.
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Glucagon
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Name the hormone that causes an increase in intracellular sugar.
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Insulin
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Name the hormone that causes a decrease in intracellular sugar.
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Glucagon
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Name the hormone that stimulates secretion of pancreatic digestive enzymes.
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Cholecystokinen
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Name the hormone that works antagonistically to glucagon.
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Insulin
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Name the hormone that stimulates the production of pancreatic fluid.
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Secretin
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What does the pancreatic fluid contain?
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Water, bicarbonate, and zymogens
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What are zymogens?
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Enzymes in their inactive form.
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Why must enzymes be in an inactive state while in the pancreas?
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They would eat the pancreatic duct before they arrive in the small intestine.
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Name the activated enzymes that enter the small intestine from the pancreas and what
they digest.
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Pancreatic amylases digest starch Pancreatic lipases digest lipids
Pancreatic proteases digest proteinPancreatic nucleases digest nucleic acids
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Insulin deficiency results in what disease?
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Diabetes mellitus
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What is the grown up name for high blood sugar?
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Hyperglycemia
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What is the name for low blood sugar?
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Hypoglycemia