5-EAPB - swgdrug.org · EI Mass Spectrum: 5-EAPB HCl; Lot# 0455564-11 40 60 80 100 120 140 160 180...
Transcript of 5-EAPB - swgdrug.org · EI Mass Spectrum: 5-EAPB HCl; Lot# 0455564-11 40 60 80 100 120 140 160 180...
5-EAPBThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 4/4/2016 Page 1 of 5SWGDRUG.org/monographs.htm
1. GENERAL INFORMATION
IUPAC Name: 1-(1-benzofuran-5-yl)-N-ethylpropan-2-amine
CAS#: 1823776-22-2 (HCl)
Synonyms: 5-(2-ethylaminopropyl)benzofuran
Source: DEA Reference Material Collection
Appearance: White powder (Hydrochloride)
UVmax(nm): Not determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
Form Chemical Formula Molecular Weight Melting Point (oC)
Base C13H17NO 203 Not Determined
HCl C13H17NO HCl 239 154.7
O CH3
NH CH3
5-EAPBThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 4/4/2016 Page 2 of 5SWGDRUG.org/monographs.htm
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~6 mg/mL in D2O co ntaining TSP for 0 ppm reference and maleic acid as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm
Pulse angle: 90o
Delay between pulses: 45 seconds
1HNMR: 5-EAPB HCl; Lot# 0455564-11; D2O; 400MHz
7.5 7.0 6.5 6.0 5.5 5.0 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5 0
61311121
7.775
1
7.5757.550
2
7.26 7.24
1
6.895 6.885
1
3.65 3.60
1
3.20 3.15 3.10
3
2.950
1
1.275
6
maleic acid HDO
TSP
5-EAPBThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 4/4/2016 Page 3 of 5SWGDRUG.org/monographs.htm
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~5 mg/mL in CHCl3 (1M NaOH extraction)
Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25 µmCarrier Gas: Helium at 1.0 mL/minTemperatures: Injector: 280oC MSD transfer line: 280oC
MS Source: 230oC MS Quad: 150oCOven program:
1) 100oC initial temperature for 1.0 min2) Ramp to 300oC at 12 oC/min3) Hold final temperature for 9.0 min
Injection Parameters: Split Ratio = 20:1, 1 µL injectedMS Parameters: Mass scan range: 30-550 amu Threshold: 100
Tune file: stune.u Acquisition mode: scanRetention Time: 7.300 min
EI Mass Spectrum: 5-EAPB HCl; Lot# 0455564-11
m/z200180160140120100806040
[x 1
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3030303030303030303030303030303030303030303044444444444444444444444444444444444444444444 44444444444444444444444444444444444444444444
5151515151515151515151515151515151515151515156565656565656565656565656565656565656565656
6262626262626262626262626262626262626262626263636363636363636363636363636363636363636363
72727272727272727272727272727272727272727272
7777777777777777777777777777777777777777777789898989898989898989898989898989898989898989
91919191919191919191919191919191919191919191102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102
115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115115 131131131131131131131131131131131131131131131131131131131131131131
131131131131131131131131131131131131131131131131131131131131131131144144144144144144144144144144144144144144144144144144144144144144145145145145145145145145145145145145145145145145145145145145145145
158158158158158158158158158158158158158158158158158158158158158158159159159159159159159159159159159159159159159159159159159159159159
186186186186186186186186186186186186186186186186186186186186186186188188188188188188188188188188188188188188188188188188188188188188
202202202202202202202202202202202202202202202202202202202202202202
m/z200180160140120100806040
[x 1
04 ]In
tens
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2
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30303030303030303030303030303030303030303030
42424242424242424242424242424242424242424242
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50505050505050505050505050505050505050505050
5151515151515151515151515151515151515151515156565656565656565656565656565656565656565656
62626262626262626262626262626262626262626262
63636363636363636363636363636363636363636363
64646464646464646464646464646464646464646464
72727272727272727272727272727272727272727272
7373737373737373737373737373737373737373737377777777777777777777777777777777777777777777
8989898989898989898989898989898989898989898991919191919191919191919191919191919191919191
91919191919191919191919191919191919191919191102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102102 103103103103103103103103103103103103103103103103103103103103103103
115115115115115115115115115115115115115115115115115115115115115115
115115115115115115115115115115115115115115115115115115115115115115
116116116116116116116116116116116116116116116116116116116116116116128128128128128128128128128128128128128128128128128128128128128128
131131131131131131131131131131131131131131131131131131131131131131
131131131131131131131131131131131131131131131131131131131131131131
143143143143143143143143143143143143143143143143143143143143143143144144144144144144144144144144144144144144144144144144144144144144 145145145145145145145145145145145145145145145145145145145145145145
157157157157157157157157157157157157157157157157157157157157157157158158158158158158158158158158158158158158158158158158158158158158 159159159159159159159159159159159159159159159159159159159159159159
186186186186186186186186186186186186186186186186186186186186186186188188188188188188188188188188188188188188188188188188188188188188
202202202202202202202202202202202202202202202202202202202202202202
5-EAPBThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 4/4/2016 Page 4 of 5SWGDRUG.org/monographs.htm
3.3 INFRARED SPECTROSCOPY (FTIR)
Instrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 8Aperture: 150
FTIR ATR (Diamond 1 Bounce): 5-EAPB HCl; Lot# 0455564-11
Wavenumber (cm-1)4000 3500 3000 2500 2000 1500 1000
%Tr
ansm
ittan
ce
60
65
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426426426426426426426426426426426426426426426426426426426426426426
455455455455455455455455455455455455455455455455455455455455455455
604604604604604604604604604604604604604604604604604604604604604604646
646646646646646646646646646646646646646646646646646646646646646
746746746746746746746746746746746746746746746746746746746746746746
760760760760760760760760760760760760760760760760760760760760760760771
771771771771771771771771771771771771771771771771771771771771771
785785785785785785785785785785785785785785785785785785785785785785
802802802802802802802802802802802802802802802802802802802802802802
881881881881881881881881881881881881881881881881881881881881881881
901901901901901901901901901901901901901901901901901901901901901901
1026102610261026102610261026102610261026102610261026102610261026102610261026102610261026
1128112811281128112811281128112811281128112811281128112811281128112811281128112811281128
1201120112011201120112011201120112011201120112011201120112011201120112011201120112011201
1265126512651265126512651265126512651265126512651265126512651265126512651265126512651265
1390139013901390139013901390139013901390139013901390139013901390139013901390139013901390
1448144814481448144814481448144814481448144814481448144814481448144814481448144814481448
1468146814681468146814681468146814681468146814681468146814681468146814681468146814681468
1535153515351535153515351535153515351535153515351535153515351535153515351535153515351535
2685268526852685268526852685268526852685268526852685268526852685268526852685268526852685
2760276027602760276027602760276027602760276027602760276027602760276027602760276027602760
2877287728772877287728772877287728772877287728772877287728772877287728772877287728772877
2989298929892989298929892989298929892989298929892989298929892989298929892989298929892989
3090309030903090309030903090309030903090309030903090309030903090309030903090309030903090
Wavenumber (cm-1)1760 1680 1600 1520 1440 1360 1280 1200 1120 1040 960 880 800 720 640
%Tr
ansm
ittan
ce
60
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403403403403403403403403403403403403403403403403403403403403403403
426426426426426426426426426426426426426426426426426426426426426426
455455455455455455455455455455455455455455455455455455455455455455
492492492492492492492492492492492492492492492492492492492492492492
604604604604604604604604604604604604604604604604604604604604604604646
646646646646646646646646646646646646646646646646646646646646646
746746746746746746746746746746746746746746746746746746746746746746
760760760760760760760760760760760760760760760760760760760760760760771
771771771771771771771771771771771771771771771771771771771771771
785785785785785785785785785785785785785785785785785785785785785785
802802802802802802802802802802802802802802802802802802802802802802
845845845845845845845845845845845845845845845845845845845845845845
868868868868868868868868868868868868868868868868868868868868868868
881881881881881881881881881881881881881881881881881881881881881881
901901901901901901901901901901901901901901901901901901901901901901
949949949949949949949949949949949949949949949949949949949949949949
1026102610261026102610261026102610261026102610261026102610261026102610261026102610261026
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1128112811281128112811281128112811281128112811281128112811281128112811281128112811281128
1144114411441144114411441144114411441144114411441144114411441144114411441144114411441144
1180118011801180118011801180118011801180118011801180118011801180118011801180118011801180
1201120112011201120112011201120112011201120112011201120112011201120112011201120112011201
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1265126512651265126512651265126512651265126512651265126512651265126512651265126512651265
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13111311131113111311131113111311131113111311131113111311131113111311131113111311131113111336
1336133613361336133613361336133613361336133613361336133613361336133613361336133613361373
1373137313731373137313731373137313731373137313731373137313731373137313731373137313731390
139013901390139013901390139013901390139013901390139013901390139013901390139013901390
1448144814481448144814481448144814481448144814481448144814481448144814481448144814481448
1468146814681468146814681468146814681468146814681468146814681468146814681468146814681468
1535153515351535153515351535153515351535153515351535153515351535153515351535153515351535
5-EAPBThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 4/4/2016 Page 5 of 5SWGDRUG.org/monographs.htm
https://en.wikipedia.org/wiki/5-EAPB
http://forendex.southernforensic.org/index.php/detail/index/1303
4. ADDITIONAL RESOURCES
Wikipedia
Forendex