4957939 Sterile pharmaceutical compositions of gadolinium chelates useful enhancing nmr imaging

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New Patents xiii 4957924 THERAPEUTIC VALINE ESTERS OF ACYCLOVIR AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Lilia M Beauchamp assigned to Burroughs Well- come Co 4958023 2-PYRIDINE CARBOTHIOAMIDES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME The present invention relates to certain amino acid exters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment of herpes virus infec- tions. The invention also includes pharma- ceutical formulations and processes for the preparation of such compounds. William A Kinney, Nancy E Lee assigned to American Home Products Corporation There are provided gastric antiulcer and cyto- protective substituted N-phenyl 2 pyridinecar- bothioamides. The process for their production and formulation is disclosed. 4957929 4-PHENYL-4.(N (PHENYL)AMIDO) PIPERIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS EMPLOYING SUCH COMPOUNDS Linas V Kudzma, H Kenneth Spencer, Sherry A Severnak assigned to BOC Inc Compounds are disclosed of the formula See Pa- tent for Chemical Structure where R2 is unsub- stituted or substituted phenyl, R3 is lower alkyl, lower cycloalkyl or lower alkoxy lower alkyl, and L is selected from a wide variety of groups. This new class of compounds exhibit improved analgesic and anesthetic properties. 4957939 STERILE PHARMACEUTICAL COMPOSITIONS OF GADOLINIUM CHELATES USEFUL ENHANCING NMR IMAGING Heinz Gries, Douwe Rosenberg, Hanns- Joachim Weinmann, Berlin, Federal Republic Of Germany assigned to Schering Aktiengesel- lschaft Pharmaceutical compositions comprising gadolinium chelates are useful for enhancing NMR images. 4959054 PHARMACEUTICALLY PROTECTED PERCUTANEOUS DEVICES Gunther Heimke, Andreas F von Recum, Arun Shanbhag assigned to Clemson University A percutaneous implant device includes a struc- ture for storing a bioreactive agent such as an antimicrobic agent, an anti-inflammatory drug, a growth hormone, and an antifungal drug. The structure can take the form of a container or a solid solution. The percutaneous device has a conduit, and the structure containing the bio- reactive agent is disposed under the skin and around the conduit in the vicinity where the con- duit passes through the skin of the living host. The structure containing the bioreactive agent is refillable via either a wall which is penetrable and reseals after penetration, or an access opening which can be opened or closed and is accessible from outside the living host. The container can include a wall having a diffusion coefficient which increases the rate of diffusion with in- creasing local temperature. 4959213 PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PREVENTION OF DISEASES OF THE SKIN INVOLVING AN INFLAMMATORY PROCESS Joel Brod, Michel Kermici, Paris, France as- signed to L'Oreal

Transcript of 4957939 Sterile pharmaceutical compositions of gadolinium chelates useful enhancing nmr imaging

Page 1: 4957939 Sterile pharmaceutical compositions of gadolinium chelates useful enhancing nmr imaging

New Patents xiii

4957924

THERAPEUTIC VALINE ESTERS OF ACYCLOVIR AND

PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

Lilia M Beauchamp assigned to Burroughs Well- come Co

4958023

2-PYRIDINE CARBOTHIOAMIDES,

PROCESSES FOR PREPARATION THEREOF AND

PHARMACEUTICAL COMPOSITIONS COMPRISING

THE SAME

The present invention relates to certain amino acid exters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment of herpes virus infec- tions. The invention also includes pharma- ceutical formulations and processes for the preparation of such compounds.

William A Kinney, Nancy E Lee assigned to American Home Products Corporation

There are provided gastric antiulcer and cyto- protective substituted N-phenyl 2 pyridinecar- bothioamides. The process for their production and formulation is disclosed.

4957929

4-PHENYL-4.(N (PHENYL)AMIDO) PIPERIDINE COMPOUNDS AND

PHARMACEUTICAL COMPOSITIONS EMPLOYING

SUCH COMPOUNDS

Linas V Kudzma, H Kenneth Spencer, Sherry A Severnak assigned to BOC Inc

Compounds are disclosed of the formula See Pa- tent for Chemical Structure where R2 is unsub- stituted or substituted phenyl, R3 is lower alkyl, lower cycloalkyl or lower alkoxy lower alkyl, and L is selected from a wide variety of groups. This new class of compounds exhibit improved analgesic and anesthetic properties.

4957939

STERILE PHARMACEUTICAL COMPOSITIONS OF

GADOLINIUM CHELATES USEFUL ENHANCING NMR

IMAGING

Heinz Gries, Douwe Rosenberg, Hanns- Joachim Weinmann, Berlin, Federal Republic Of Germany assigned to Schering Aktiengesel- lschaft

Pharmaceutical compositions comprising gadolinium chelates are useful for enhancing N M R images.

4959054

PHARMACEUTICALLY PROTECTED PERCUTANEOUS

DEVICES

Gunther Heimke, Andreas F von Recum, Arun Shanbhag assigned to Clemson University

A percutaneous implant device includes a struc- ture for storing a bioreactive agent such as an antimicrobic agent, an anti-inflammatory drug, a growth hormone, and an antifungal drug. The structure can take the form of a container or a solid solution. The percutaneous device has a conduit, and the structure containing the bio- reactive agent is disposed under the skin and around the conduit in the vicinity where the con- duit passes through the skin of the living host. The structure containing the bioreactive agent is refillable via either a wall which is penetrable and reseals after penetration, or an access opening which can be opened or closed and is accessible from outside the living host. The container can include a wall having a diffusion coefficient which increases the rate of diffusion with in- creasing local temperature.

4959213

PHARMACEUTICAL COMPOSITION FOR

TREATMENT AND/OR PREVENTION OF DISEASES OF

THE SKIN INVOLVING AN INFLAMMATORY PROCESS

Joel Brod, Michel Kermici, Paris, France as- signed to L'Oreal