3

CONTENTS

Committees of the 3rd International H.S.S.B.M. Scientific Meeting ....................5

Acknowledgements ................................................................................................................7

Invitation Letter ........................................................................................................................8

Scientific Programme ............................................................................................................9

List of Speakers ....................................................................................................................11

Registrations ..........................................................................................................................12

Social Events ..........................................................................................................................13

General Information ............................................................................................................14

Hotel Reservations................................................................................................................15

Airplane Fare ..........................................................................................................................16

Chartered Flight ....................................................................................................................18

5

PresidentsPaschalis Εleftherios

Skarantavos Grigorios

Executive Committee H.S.S.B.M. 2007 - 2008 President: Τrovas Georgios

Vice President: Karachalios Theofilos Gen. Secretary: Papadopoulou Fotini

Treasurer: Kaskani EvageliaMembers: Antypas George

Georgakopoulos Nikolaos Kataxaki Εvangelia

Οrganizing CommitteeAntypas George

Georgakopoulos Nikolaos Daskalakis Stavros

Kaklamanis NikolaosKaplanoglou TheofaniaKarachalios Theofilos

Kaskani Εvangelia Kataxaki Εvangelia

Katsibri PelagiaKiassos EmanouilMetania Eleftheria

Papadopoulou Fotini Christakopoulos Georgios

Scientific Committee

Agnusdei Donato ItalyEriksen Erik Fink Switzerland

Eastell Richard U.KFelsenberg Dieter GermanyKlaushofer Klaus Austria

Papapoulos Socrates The NetherlandsPaschalis Eleftherios Austria

Phipps Roger U.S.ARoschger Paul Austria

Russell Graham U.KSchiessl Hans Germany

Skarantavos Grigorios GreeceTolis Georgios Greece

Trovas Georgios Greece

Committees of the 3rd International H.S.S.B.M. Scientific Meeting

6

SeminarSecretariat

PCO CONVIN S.A.Costa Varnali str 29, 152 33 ChalandriTel: +30 210 6833600, Fax: +30 210 6847700E-mail: congress@pco-convin.gr

Organized by

HELLENIC SOCIETY FOR THE STUDYOF BONE METABOLISM 2 Thrakis Street, 151 24 Maroussi Tel./Fax: +30 2106128606 e-mail: eemmo@otenet.gr

Under the Auspices of

7

ACKNOWLEDGEMENTS

The Organizing Committee of the 3rd International Scientific Seminar H.S.S.B.M. wishto thank all Sponsors and Exhibitors listed below, for their support to the Scientific andSocial program of the Seminar.

MAIN SPONSOR

GOLD SPONSOR

SILVER SPONSOR

SPONSORS

8

INVITATION LETTER

Dear colleagues,

We would like to invite you to the 3d International Bone Strength and Quality Meeting,which will take place in September 29 and 30, 2007, on Samos Island, Greece.

Bone Strength has always been the main investigational and therapeutical target forscientists and therapists in Bone field. Bone Quality has lately emerged as an umbrellaterm to shelter new information, beyond bone surface density and surface mass,leading to a better understanding of bone strength. The Quality concept is rapidlyevolving flooding with information that certainly need evaluation and explanation. Thisis the reason we continue and organize this meeting for a third time, bearing in mindthe elegant presentations, the vigorous discussions inside and outside the auditoriumand last but not least the enthousiastic social atmosphere.

Those of you who participated in the 1st and 2nd meeting in Rhodes and Corfu islandwill notice that the 3d meeting is more clinical oriented. This is meant so that researchknowledge is made available and thus tested in practice by clinitians and on the otherhand feedback clinical information can be transferred back to the laboratory. As onthe past, plenty of time for discussion will be available in both days.

We are certain that the Meeting will be of great value both for clinicians and basicscientists providing the chance to exchange ideas and information on the most recentadvances in Bone Science and at the same time to contribute to the betterunderstanding of Bone Biology and the impact it bares for clinical practice.

The mixture of the highly scientific and comprehensive program with a varied andexciting social program is the recipe for success and we have therefore adhered to thesevital ingredients. The Combination of the excellent accommodations, conference facilitiesand the wonderful climate guarantee the success of the meeting.

We very much look forward to welcoming you to the beautiful island of Samos!

Sincerely Yours

Lefteris Paschalis Grigoris Skarantavos

Presidents of the Organizing Committee

9

SCIENTIFIC PROGRAMME

Friday, September 28, 2007

08.30 - 15.30 Registrations

20.00 - 20.30 Opening Ceremony - President’s Welcome Address - Greetings

21.00 Welcome Reception

Saturday, September 29, 2007

08.30 - 15.30 Registrations

09.00 - 09.30 Modern view of remodelingEriksen Erik, Switzerland

09.30 - 10.00 Effects of non osteoporotic drugs on boneEastell Richard, U.K

10.00 - 10.30 Cortical porosityPhipps Roger, U.S.A

10.30 - 11.00 Bisphosphonate differencesRussell Graham, U.K

11.00 - 11.30 Metastatic diseases and bisphosphonatesPapapoulos Socrates, The Netherlands

11.30 - 12.00 Jaw osteonecrosisFelsenberg Dieter, Germany

12.00 - 13.00 Light Lunch - Break

13.00 - 13.30 Liver transplant patients and zolendronateKlaushofer Klaus, Austria

13.30 - 14.00 Contribution of vitamin D and Ca supplementation when interpreting clinical results of BisphosphonatesRoschger Paul, Austria

14.00 - 14.30 Biomechanics in boneSchiessl Hans, Germany

14:30-15:00 Collagen Participation in Bone StrengthPaschalis Eleftherios, Austria

15.00 - 15.30 Clinical interpretation of pQCTSkarantavos Grigorios, Greece

10

Sunday, September 30, 2007

08.30 - 14.30 Registrations

09.00 - 09.30 FosamaxPapapoulos Socrates, The Netherlands

09.30 - 10.00 ActonelRoger Phipps, Η.Π.Α

10.00 - 10.30 BonvivaPapapoulos Socrates, The Netherlands

10.30 - 11.00 AclastaEriksen Erik, Switzerland

11.00 - 11.30 ProtelosTo be announced

11.30 - 12.00 EvistaAgnusdei Donato, Italy

12.00 - 13.00 Light Lunch - Break

13.00 - 13.30 PreotactTo be announced

13.30 - 14.00 ForsteoAgnusdei Donato, Italy

14.00 - 14.30 Conclusions - End of Scientific Meeting

11

LIST OF SPEAKERS

� AGNUSDEI DONATO: MD, Ass. Professor, Medical Fellow Osteoporosis Europeand Latin America, Florence, Italy

� ERIKSEN ERIK FINK: MD, DMSc, Senior Clinical Consultant ABH TA, NovartisPharma AG, Basel, Switzerland

� EASTELL RICHARD: MD, PRCP, Professor Human Metabolism and ClinicalBiochemistry, University of Sheffield, Northern General Hospital, Clini. Sci. Ctr.United Kingdom

� FELSENBERG DIETER: Professor, MD, PhD, Center of Muscle and Bone Research,Department of Radiology, Charite University Medicine Berlin Campus BenjaminFranklin, Berlin, Germany

� KLAUSHOFER KLAUS: Univ., Prof., MD, Professor, Ludwig Boltzmann - Institutfur Osteologie im Hanusch-Krankenhaus der WGKK und UnfallkrankenhausMeidling der AUVA, Wien, Austria

� PAPAPOULOS SOCRATES: Professor, Department of Endocrinology UniversityMedical Center, Leiden, The Netherlands

� PASCHALIS ELEFTHERIOS: Ph.D, Senior Scientist, Ludwig Boltzmann - Institutfur Osteologie im Hanusch-Krankenhaus der WGKK und UnfallkrankenhausMeidling der AUVA, Wien, Austria

� PHIPPS ROGER: Ph.D, Principal Scientist, New Drug Development, Procter & Gamble, P & G Pharmaceuticals Inc, Mason, U.S.A

� RUSSELL GRAHAM: Norman Collisson, Professor of Musculoskeletal Sciences,Institute Director and Head of Department. The Botnar Research Center andOxford University Institute of Musculoskeletal Sciences, Nuffield Department of Orthopaedic Surgery, Nuffield Orthopaedic Centre, Headington, Oxford,United Kingdom

� ROSCHGER PAUL: Ph.D, Ludwig Boltzmann - Institut fur Osteologie imHanusch - Krankenhaus der WGKK und Unfallkrankenhaus Meidling der AUVA,Wien, Austria

� SCHIESSL HANS: Stratec Medizintechnik, Pforzheim, Germany

� SKARANTAVOS GRIGORIOS: Rheumatologist Director, Metabolic Bone Unit, A’ Orthopedic Clinic Attikon University Hospital, Athens, Greece

12

REGISTRATIONS

RATES until July, 30th 2007 from July 31st, 2007 and up to the time of the conference

H.S.S.B.M. Members x 290,00 x 320,00

Non-members x 330,00 x 410,00

Interns x 180,00 x 200,00

Accompanying persons x 80,00 x 80,00

Registration entitles the participants to:

• Attendance of the scientific program• A folder with all printed material • The final program• Certificate of attendance• Coffee• Participation in the Opening Ceremony and Welcoming Reception• Participation in the Gala Dinner

Registration fees for Accompanying persons include:

• Entrance to the seminar area • Participation in the Opening Ceremony and Welcoming Reception• Participation in the Gala Dinner

• Please note that the reduced registration rates are valid only if your registrationform and payment have been received by Monday, July 30th 2007 by PCO CONVIN S.A., Seminar Secretariat: Τel: +30 210 6833600, Fax: +30 210 6847700, e-mail: congress@pco-convin.gr

Cancellation of Registrations

• For cancellations submitted in writing to the Seminar Secretariat until July 30th,2007, x 50,00 will be withheld as expenses for Secretariat Support.

• For cancellations submitted in writing to the Seminar Secretariat between July31st and August 10th, 2007, 50% of the total registration fee will be withheld ascancellation cost.

• No return of funds is possible for cancellations submitted after August 11th, 2007.

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SOCIAL EVENTS

Friday September 28, 2007Time: 20:00 Opening Ceremony/Welcoming Reception

Saturday September 29, 2007Time: 21:00 Formal Dinner, Hotel Doryssa

Seaside Resort, Village square

• Due to limited availability, confirmation of participations in the Social events is mandatory.

• Please confirm your participation, as well as that of your escort(s), to the Secretariatof the Seminar, upon reception of the printed material for the Seminar.

• Numbered invitations, (delivered by the Seminar Secretariat, upon confirmation ofparticipation), will be required for the entrance of the participants and escorting partiesin the areas where social events are being held.

TRANSPORTATION BY BUS

• Private busses have been hired for the transportation of the participants and escortingparties from the area of the Seminar, to the place where the Opening Ceremony andWelcoming Reception will be held.

• The Seminar Secretariat will announce times of departure and return on that same day.

14

GENERAL INFORMATION

Place

The Hotel "DORYSSA SEASIDE RESORT" in Samos

• Seminar Secretariat, ground floor of the main building • Seminar Hall, DIDO (1st floor, main building)• Exhibition Area, ground floor of the main building & DIDO Foyer

(1st Floor, main building)• Slides Reception, DIDO Foyer

(1st Floor, main building)

Dates

Friday September 28, 2007Saturday September 29, 2007Sunday September 30, 2007

Working hours for the Secretariat of the Seminar

During the course of the Seminar, the Secretariat will be open duringthe following hours:

Friday September 28, 2007 16:00-19:30Saturday September 29, 2007 08.30-15:30Sunday September, 30 2007 08:30-14:30

Official Language

English will be the official language for the Seminar. There will be simultaneoustranslation from English to Greek during the course of the Seminar.

Commercial Exhibition

During the course of the Seminar there will be a Commercial Exhibition of Pharmaceutical Supplies (Products).

Contact Address before and after the completion of the Seminar

PCO CΟΝVIN S.A.

Costa Varnali str 29, 152 33 ChalandriTel: +30 210 6833600, Fax: +30 210 6847700E-mail: congress@pco-convin.gr

Final Program

The Secretariat will provide the final program of the Seminar for the participants,upon presentation of confirmation of pre-registration.The schedule will also appearin the electronic address www.eemmo.gr

Projections - Slides

Speeches can be projected during the course of the Seminar, either using slides,or through a computer data projector and overhead projector. Speakers arerequested to deliver their work in electronic form to the Slide Reception, at least1 hour before each event.

15

HOTEL RESERVATIONS

In order to ensure the accommodation of all the participants to the 3rd InternationalScientific Meeting H.S.S.B.M., PCO CONVIN S.A. has pre-reserved rooms in the Hotelwhere the Seminar will be held. As part of our tourist services, these rooms are offeredin special reduced prices, as analytically described in the attached Hotel ReservationForm.

Hotel Rating One-bed room Two-bed room

DORYSSA SEASIDE RESORT 4**** x 130,00 x 180,00

• The above-mentioned prices are per room with half-board, per day. A 2-day stay ismandatory.

• For those participants who wish to extend their stay at the Hotel, the special Seminar priceswill be secured, provided that they make their reservations and payments through theSeminar Secretariat of PCO CONVIN S.A.

Cancellation Policy

• For cancellations of reservations, submitted in writing to the Secretariat of theSeminar (PCO CONVIN S.A.) up to July 15th, 2007, 50% of the total cost will bewithheld as cancellation fees.

• No return of funds will be possible for cancellations submitted to the SeminarSecretariat after July 16st, 2007.

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AIRPLANE FARE

Catering to the needs of all participants to the 3rd International Scientific MeetingH.S.S.B.M., PCO CONVIN S.A. has secured seats on several flights of different companies,which are listed below:

REGULAR FLIGHT

1. Aegean Airlines

From Athens to Samos

From Athens AthensTo Samos SamosDate 28/09 28/09Departure 06:15 15:15Arrival 07:05 16:05Flight No. Α3 240 Α3 244

From Samos to Athens

From Samos SamosTo Athens AthensDate 30/09 30/09Departure 07:40 16:40Arrival 08:30 17:30Flight No. Α3 241 Α3 245

Airfare xx 180,00 + xx 44,00 Airport taxes + xx 26,00 fuel charge

Note: The above prices include transportation from and to the airport of Samos.

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2. Olympic Airways

From Athens to Samos

From Athens AthensTo Samos SamosDate 28/09 28/09Departure 08:45 12:25Arrival 09:45 13:25Flight No. OA 752 OA 754

From Samos to Athens

From Samos SamosTo Athens AthensDate 30/09 30/09Departure 10:10 13:50Arrival 11:10 14:50Flight No. OA 753 OA 766

Airfare xx 175,00 + xx 65,00 Airport taxes and fuel charge

From Samos to Athens

From SamosTo AthensDate 30/09Departure 19:25Arrival 20:25Flight No. OA 759

If the above Flight is chosen, the prices are as follows:Airfare xx 185,00 + xx 65,00 Airport taxes and fuel charge

Note: The above prices include transportation from and to the airport of Samos.

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CHARTERED FLIGHT

For the convenience of all participants, the Secretariat of the Seminar (PCO CONVIN S.A.)has arranged chartered Flights from Athens to Samos on September 28th and fromSamos to Athens on September 30th, 2007. The exact timetables for these flights willbe announced later.

Aegean Airlines Airplane Type AVRO RJ - 100

From Athens to Samos

From Athens AthensTo Samos SamosDate 28/09 28/09DepartureArrivalFlight No.

From Samos to Athens

From Samos SamosTo Athens AthensDate 30/09 30/09DepartureArrivalFlight No.

Airfare xx 320,00 + xx 44,00 Airport taxes

Note: Due to limited availability of seats in the regular flights, bookings will bemade strictly on a first-come, first-serve basis.

CANCELLATION POLICY

• For cancellations of seat reservations, submitted in writing to the Secretariat ofthe Seminar (PCO CONVIN S.A.) up to July 31st, 2007, 50% of the total cost willbe withheld as cancellation fees.

• No return of funds will be possible for cancellations submitted to the SeminarSecretariat after 1st August, 2007.

NOTES