3 .2011 BIOTRANSFORMATION 1

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    0885/84:-0209,-4900885/84:-0209,-490

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    4343032,9.497,381472,943032,9.497,381472,943

    ##

    4112,323,9434112,323,943

    14721472 4141 -497,381472,943-497,381472,943 33 .. 90709070 8885439,304:885439,304:8 ,907,943,907,943 33 .02.,.02., 897:.9:70897:.9:70 4141 ,,

    /7:/7: ,8,8 ,, 708:9708:9 4141 .,30.,30 4141 9090 55 4141 -4/-4/ 1:/81:/8

    0320803208 /4/4 349349 5,79.5,905,79.5,90

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    43/64

    ,2508,2508

    4343032,9.497,381472,943032,9.497,381472,943

    97,.:7:297,.:7:2 ,:/,34830":,9073,7,./,:/,34830":,9073,7,./

    0,2300,230 ,9,./.541:730,9,./.541:730 472,/0/0472,/0/047,05,9047,05,90 08209,05,208209,05,2

    ,9,./.53908942,.,9,./.53908942,.

    :8930:8930 0.4709,2300.4709,230 9030243:29030243:2

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    44/64

    %#$%#$

    %#$#%%#$#%

    %0574/:.03/;/:,;,7,9433/7:%0574/:.03/;/:,;,7,9433/7:

    209,-482209,-482

    0309.1,.94780309.1,.9478

    43430309.1,.94780309.1,.9478

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    45/64

    43430309.1,.94780309.1,.9478

    7:7:7:3907,.94387:3907,.9438 3203/:.9433203/:.9433203-9433203-943

    080080

    093;7432039,,.9478093;7432039,,.9478 $243$243.4482548:70945089./08.4482548:70945089./08

    3907,.9438-090037:83/4034:83907,.9438-090037:83/4034:8.4254:3/8.4254:3/8

    !,944.,89,90841;07'$:38!,944.,89,90841;07'$:3803/4.730803/4.7308

    :97943,89,9:889,7;,9432,3:97943:97943,89,9:889,7;,9432,3:97943

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    46/64

    3203/:.9433203/:.943

    013943013943

    98983.70,80/,.9;941!032083.70,80/,.9;941!03208 -.079,3-.079,3

    /7:847.02.,8/:0943.70,80/839088/0.70,80//7:847.02.,8/:0943.70,80/839088/0.70,80//07,/,94341800.90/03208/07,/,94341800.90/03208,..007,93908:-897,90,..007,93908:-897,90

    209,-482/0.70,835,82,0;080,/394209,-482/0.70,835,82,0;080,/394

    907,50:9.1,:70907,50:9.1,:70

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    47/64

    3203/:.9433203/:.943

    ,250,250

    %4/7:8;03940907430803203/:.07%4/7:8;03940907430803203/:.07 7:3907,.94387:3907,.9438

    ,71,7347,,39.4,:,39,71,7347,,39.4,:,395034-,7-9,5034-,7-9,

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    48/64

    3203/:.0783203/:.078

    %0/7:8574/:.303203/:.943,70343%0/7:8574/:.303203/:.943,70343,83203/:.078,83203/:.078

    %0803.:/0%0803.:/0 ',74:8/7:8',74:8/7:8 !034-,7-9,503943#1,253!034-,7-9,503943#1,253

    ,7-,2,05300,209,8430,7-,2,05300,209,8430

    02.,802.,8 380.9./08380.9./08 ,3/,3/ 3;7432039,54:9,3983;7432039,54:9,398

    %4-,..48240,7.4,%4-,..48240,7.4,-740/20,9.,33/:.0!-740/20,9.,33/:.0!03208%0.439,303403208%0.439,3034--((570304907,742,9.570304907,742,9./74.,7-438/74.,7-438

    //

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    49/64

    3203/:.0783203/:.078

    !034-,7-9430!034-,7-9430 !!

    !03943,7-,2,0530!03943,7-,2,0530

    4907,39.43;:8,3984907,39.43;:8,398

    :.4.479.4/8:.4.479.4/8$4204907$4204907

    $9074/8,.74/08$9074/8,.74/08

    !!

    034034--(57030394-,..4(57030394-,..4

    82408240

    !!

    .4482843,/.4482843,/ !!

    #1,253#1,2530,209,84300,209,8430 !3;07390893,!3;07390893,2:.48,2:.48,

    41-7,9041-7,90 !!

    ,7-,2,0530,7-,2,0530 :943/:.943:943/:.943

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    50/64

    43806:03.0841.74842,3203/:.94343806:03.0841.74842,3203/:.943

    %07,50:9.1,:70:094/0.70,80/5,82,%07,50:9.1,:70:094/0.70,80/5,82,.43..43.01,:7041.4397,.05943947,01,:7041.4397,.05943947,.4397,.059;0803;039#1,253.4397,.059;0803;039#1,2533/:.073/:.07

    3.70,80/94.941/7:8,.9;,90/9494.3.70,80/94.941/7:8,.9;,90/9494.209,-4908209,-49080.:905,7,.09,2494.90.:905,7,.09,2494.94..:78,9407/480835,9039870.0;34..:78,9407/480835,9039870.0;303203/:.07803203/:.078

    !,72,.4309.9407,3.0!,72,.4309.9407,3.0190/7:3/:.08190/7:3/:.089843209,-482,:949843209,-482,:943/:.9433/:.943

    0,7-,2,0530#1,2530,7-,2,0530#1,253

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    51/64

    ,8907209,-48241,8907209,-48241842003/4034:8842003/4034:88:-897,90889074/8-7:-38:-897,90889074/8-7:-3

    !70.59,94341,.:90390729903954757,!70.59,94341,.:90390729903954757,

    3.70,80/547573839088-/0705708833.70,80/547573839088-/070570883,2340;:03.,./83909,80,2340;:03.,./83909,80

    3907299039:8041,33/:.073907299039:8041,33/:.07 2,3907107092,390710709

    /480,/:89203941/7:85708.7-0/4370:,7/480,/:89203941/7:85708.7-0/4370:,7-,88-,88

    047,,39047,,39.4,:,39847,54.,02.8.4,:,39847,54.,02.8

    ,39,39 05059.8,3905059.8,395079038;085079038;08

    43806:03.0841.74842,3203/:.94343806:03.0841.74842,3203/:.943

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    52/64

    7:8480209,-4828831.,39,110.90/7:8480209,-4828831.,39,110.90/

    -03203/:.943,70-03203/:.943,70

    !03943,71,73!03943,71,73%4-:9,2/047,2503.4%4-:9,2/047,2503.4

    7,.4397,.059;08257,2307,.4397,.059;08257,230

    4..30%045304..30%04530

    78041:;3!03-:9,43078041:;3!03-:9,430

    43806:03.0841.74842,3203/:.94343806:03.0841.74842,3203/:.943

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    53/64

    !488-0:8084103203/:.943!488-0:8084103203/:.943

    43039,34343039,343,0249.,:3/.0,0249.,:3/.0

    5034-,7-9430.,:8087,5/.0,7,3.041,:3/.05034-,7-9430.,:8087,5/.0,7,3.041,:3/.0

    :83883/7420:83883/7420 5039432,70/:.0905039432,70/:.090

    2,31089,94382,31089,9438

    743.5484338743.5484338

    ;07/80,80;07/80,80

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    54/64

    3203-9433203-943

    013943013943 %88,5034203433.%88,5034203433.

    .079,3/7:82,.079,3/7:82,3-9,.9;9413-9,.9;941!03208!03208 0110.9;070/:.0900110.9;070/:.090209,-48241549039,8:-897,908209,-48241549039,8:-897,908

    3.70,835,82,0;080,/39494.93.70,835,82,0;080,/39494.9

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    55/64

    3203-94783203-9478

    #0;078-03-947#0;078-03-9477:4798209,-4907:4798209,-490147270;078-0.4250974341!147270;078-0.4250974341!0,20,2 .425099;03-943.425099;03-943

    770;078-0$:./03-9478770;078-0$:./03-9478 7:87:8147270,.9;0209,-490.24/1147270,.9;0209,-490.24/1!545749034717,20390,2!545749034717,20390,224092409

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    56/64

    #0;078-03203-9478#0;078-03203-9478

    209/30094.43,40843,/209/30094.43,40843,/

    09743/,40;07,5023,09743/,40;07,5023,

    79742.3%740,3/42.379742.3%740,3/42.3

    :7,34.4:2,7308:7,34.4:2,7308 337,5017:9:.07,5017:9:.0

    770;078-0$:./,3-9478770;078-0$:./,3-947847,2503.447,2503.4 !74594:7,.!74594:7,.

    $0.4-,7-9430$0.4-,7-9430 $57434,.9430$57434,.9430

    3203-94783203-9478

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    57/64

    3.,831.,3.03.,831.,3.0

    3203-94783203-9478

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    58/64

    0$00$0

    9702041,09702041,0 8407209,-4828407209,-482

    09:8,3/3043,9009:8,3/3043,90 ,70;:307,-09494.,70;:307,-09494.0110.9841/7:8-0.,:800110.9841/7:8-0.,:80 0,-497,381472,9430,-497,381472,943

    !447/0;0450/!447/0;0450/

    22,9:7020.,38281470.7094322,9:7020.,38281470.70943

    !/0;04530,7,/:9,.9;993,!/0;04530,7,/:9,.9;993,10243984907!,800320/0;04510243984907!,800320/0;045247084247084

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    59/64

    33043,90833043,9085,79.:,75702,9:70-,-085,79.:,75702,9:70-,-08

    #0/:.0/:.:7434/.43:,943#0/:.0/:.:7434/.43:,943

    507-7:-302,7841073.97:8507-7:-302,7841073.97:8

    3.70,80/94.941.47,2503.4,3/454/83.70,80/94.941.47,2503.4,3/454/8

    3/073/07 0320889028/0.70,800320889028/0.70,80

    703,1:3.943/0.308703,1:3.943/0.308

    0$00$0

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    60/64

    093;7432039,,.9478093;7432039,,.9478

    ,7.4,-740/144/.7:.1074:8,7.4,-740/144/.7:.1074:8

    ;009,-08$243.4482548:7094;009,-08$243.4482548:70945089./085089./08 3203/:.0783203/:.078

    7,5017:9:.0.439,38:7,34.4:2,73087,5017:9:.0.439,38:7,34.4:2,7308

    3203-9473203-947

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    61/64

    3907,.9438-090037:83907,.9438-090037:83/4034:8.4254:3/83/4034:8.4254:3/8

    7:82,.42509014790808:-897,908

    7:82,.42509014790808:-897,908 :9,9430:.:743.,./8:1,90:9,9430:.:743.,./8:1,90

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    62/64

    !,944.,89,90841;07'$!,944.,89,90841;07'$:3803/4.7308:3803/4.7308

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    63/64

    :97943,89,9:889,7;,943:97943,89,9:889,7;,943

    2,3:979432,3:97943

  • 8/3/2019 3 .2011 BIOTRANSFORMATION 1

    64/64

    %%#$%%#$

    95.,580:/4.4308907,8095.,580:/4.4308907,80 $:..3.430$:..3.430

    $:,20943:28/7480/-580:/4.4308907,80$:,20943:28/7480/-580:/4.4308907,800309.,,-3472,580:/4.4308907,805340,0309.,,-3472,580:/4.4308907,805340,

    .09,94389,9:8.09,94389,9:8 $4,89,.09,947830790/,8,3$4,89,.09,947830790/,8,3,:94842,70.088;097,9$4,.09,9475034950,:94842,70.088;097,9$4,.09,9475034950 ,-4:9,-4:9

    1-,.890390&$:.088.4224338,381-,.890390&$:.088.4224338,380824808248

    0309.,/0907230//010.98390!/0503/0394/,9;00309.,/0907230//010.98390!/0503/0394/,9;0

    209,-48241209,-482410-7846:3!03,.093!031472309038;0209,-40780-7846:3!03,.093!031472309038;0209,-4078,3/5447209,-4078,3/5447209,-4078

    /74,94341,39.43;:8,390503943/74,94341,39.43;:8,390503943!447!447