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THUC TRTIU CHY

Ths. H Th Thch Thy

1

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NI DUNG

2

1. icng2. Cc thuc khng nhu ng rut dng

opioid3. Cc thuchpph

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i cng

3

1. Phn loitiu chy2. Phn loithuctrtiu chy3. iutrbnhtiu chy

Tiu chycp: virus, vi

khun, thcn...

Tiu chymn: thc

phm, vimrut, l,cnggip...

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i cng

Phn loi tiu chy Do nhim khun

Khng do nhimkhun thm thu (sorbitol,

glycerin...) cht gy bi tit nc v

cc chtingii (gastrin,PG...)

ri lonnhu ng(antacidc magne, chphmst...) nguyn nhn khc

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i cng

5

Phn loi thuc tr tiu chykhng nhu ng rutHp ph

Thuc khc

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i cng

6

iu trNguyn nhn?

cn bngnc- chtingii

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Thuckhng nhu ngrut: nhm opioid

7

Difenoxin (diphenoxylic acid), chtchuynha c hottnh, t tc ngdi hn

Diphenoxylat (opiat)

Loperamid

Opiat v cc dn xut

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Thuckhng nhu ngrut: nhm opioid

8

Tc dng Chmnhu ngrut Ko di (t) hpthu chtingiiv nc Tngckhiphn

Chngchnh

Tiu chynhimkhun Vim kttrng Trdi2 tui

Vai tr atropin

Trnh lm dng(atropin kch thchCNS liucao)

Opiat v cc dn xut

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Thuckhng nhu ngrut: nhm opioid

9

Chngchnh Vng da do gan

Opiat v cc dn xut Diphenoxylat 25mg Atropin sulfat 0,025mg

Difenoxin HCl 1mg Atropin sulfat 0,025mg

Tc dngph Bunnn, i ma,chngbng,to

bn Chng mt,khoi cm,qu mn

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Thuckhng nhu ngrut: nhm opioid

10

Opiat v cc dn xut Hp thu (PO) chm, ko honton

t tc dng ph hn, (t) di

hn,thucko cnk n

Tc dngph Bun nn, i ma, au bng,

kh ming Chng mt, bun ng, qu

mn

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Cc thuchpph

Calci poly carbophyl Kaolin v pectin

Dioctahedral smectitAttapulgit

Hp ph c t, vi khun,thuc,dchtiu ha, kh.

Dng ngay sau tiu chy Thuckhng c Hiuquchachngminh

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Cc thuchpph

12

Calci poly carbophyl

Nhapolyacryl thn nc,hpthnc60 ln Hiuqu,an ton

Kaolin v pectin Kaolin: aluminium silicat hydrat ha thin nhin

Pectin ly trch vqucam Trtiu chycp Cntrhpthu digoxin v mtsthuckhc

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Cc thuchpph

13

Aluminium magnesium silicat thin nhin

+ glycoprotein dchnhy,bao phnim mc, Ko hpthu qua mng rut othiqua phn

Dioctahedral smectit

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Cc thuchpph

14

Tc dngph To bn Ungxa thuckhc

Chnh Tiu chy Hichngkch thch rut Chng tro ngc thcqun

ddy

Dioctahedral smectit

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Cc thuchpph

Attapulgit Thnh phn,l tnh gingkaolinTc dngHp ph vi khun, c t, gimmtnc

Hot ha yu t V, XII ca qutrnh ngmu

ChnhTiu chy Chngchnh Trtiu chycp Qu mn

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THUC TRTIU CHY

OPIOID KHNG

NHU NG RUT

THUC HP PH

Difenoxin(diphenoxylic acid)

Diphenoxylat Loperamid

Calci poly carbophyl Kaolin v pectin

Attapulgit Dioctahedral smectit

H h

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17

khng nhu ng rut Hp ph

Thuc khc

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18

khng nhu ng rut

Hp ph

Thuc khc