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Name Indications Classifications Side Effects Contraindications Nursing

Considerations

Cefuroxime

750mg IV

It is effective for the

treatment of

penicillin ase-producing

Neisseria gonorrhoea

(PPNG). Effectively

treats bone and joint

infections, bronchitis,

meningitis,

gonorrhea, otitis

media,

pharyngitis/tonsillitis,

sinusitis, lower

respiratory tractinfections, skin and

soft tissue infections,

urinary tract

infections, and is

used for surgical

prophylaxis, reducing

or eliminating

infection.

ANTIINFECTIVE;

ANTIBIOTIC;

SECOND-GENERATION

CEPHALOSPORIN

Body as a Whole:

Thrombophlebitis (IV

site); pain, burning,cellulitis (IM site);

superinfections,

positive Coombs'

test.

GI:

Diarrhea,

nausea, antibiotic-

associated colitis.

Skin:Rash, pruritus,

urticaria.

Urogenital:

Increased serum

creatinine and BUN,

decreased creatinine

clearance.

Hypersensitivity to

cephalosporins and

related antibiotics;pregnancy

(category B),

lactation

>Determine history

of hypersensitivity

reactions tocephalosporins,

penicillins, and

history of allergies,

particularly to drugs,

before therapy is

initiated.

>Inspect IM and IV

injection sites

frequently for signs

of phlebitis.

>Report onset of

loose stools or

diarrhea. Although

pseudo membranous

colitis.

>Monitor I&O rates

and pattern:

Especially importantin severely ill patients

receiving high doses.

Report any significant

changes.

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Name Indications Classifications Side Effects Contraindications Nursing

Considerations

Ketorelac

(Toradol)

IM 30mg/amp1 amp

Short term

management of pain

(not to exceed 5 daystotal for all routes

combined)

Ophthalmic: relief of

ocular itching due to

seasonal

conjunctivitis and

relief of post-

operative

inflammation after

cataract surgery.

Nonsteroidal

anti-inflammatory

agents, nonopioidanalagesics

CNS:

Drowsiness

abnormal thinkingdizziness

euphoria

headache-

- RESP:

asthma

dyspnea

- CV:

edema

pallor

vasodilation

- GI:GI Bleeding

abnormal taste

diarrhea

dry mouth

dyspepsia

GI pain

nausea

- GU:

oliguria

renal toxicityurinary frequency

Hypersensitivity

- Cross-sensitivity

with other NSAIDsmay existPre- or

perioperative use

- Known alcohol

intoleranceUse

cautiously in:

1) History of GI

bleeding

2) Renal impair-ment

(dosage reduction

may be required)

3) Cardiovasculardisease

- Patients who have

asthma, aspirin-

induced allergy, andnasal polyps are at

increased risk for

developing

hypersensitivity

reactions. Assess for

rhinitis, asthma, and

urticaria.

- Assess pain (note

type, location, and

intensity) prior to

and 1-2 hr followingadministration.

- Ketorolac therapy

should always be

given initially by the

IM or IV route. Oral

therapy should be

used only as a

continuation of

parenteral therapy.

- Caution patient toavoid concurrent use

of alcohol, aspirin,

NSAIDs,

acetaminophen, or

other OTC

medications without

consulting health

care professional.

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