NanoMagLab provides services for both preparation and characterization of magnetic

nanostructures, in the form of thin films and multilayers -extended or nanopatterned- as

well as magnetic nanoparticles.

The service makes available to the consortium specific advanced instrumentation for

preparation (by physical and chemical means), manipulation (ultrafast-ball milling and

lithography) and characterization (including morphological, structural, electronic, magnetic,

and transport studies) of magnetic nanostructures.

( A ) Biomedical applications: magnetic nanoparticles.

( B ) Information technology: thin films and multilayers, spintronic/spin-orbitronic.

( C ) Automotive: magnetic devices based on next-generation permanent magnets .

( D ) Recycling: magnetic materials processing.

Red de Laboratorios e Infraestructuras de Madri+d (Redlab. 282)

Zetasizer Nano ZS (Malvern Instruments): tamaño, peso molecular, potencial Zeta

Chemical synthesis

Thermal decomposition of an iron organic precursor

Magnetite (Fe3O4) MNPs

Hydrodynamic sizes DMSA

coated,(water disp) 42-66 nm

Multi-purpose UHV growth/spectroscopy Lab

Four interconnected UHV chambers: (sputtering+MBE+ XPS/UPS+TDS)

Vectorial magnetometries

v-VSM v-Kerr

3.5 T,

M||, M

aH = 0º-360º

100 K- RT

> 1memu

GMM-CSIC/ GNB-IMDEA, in preparation

0,3 T,

M||, M

aH= 0º-360º

5 K- 500 K

> 0,1 nm

LASUAM/NanoMagLab-IMDEA

Cuñado et al Rev Sci. Instrum. 86, 046109 (2015)

Phys. Rev. Lett. 95, 057204 (2005); Phys. Rev. B 86, 024421 (2012)

UV-visible spectroscopy. Quantify the efficiency of biofunctionalization of NPs, by determining the

structure and stability of biomolecules (DNA , RNAi and antibodies) before & after their conjugation.

Cary 5000 UV - VIS -NIR , with temperature controller and Peltier thermostat.

Purchased in 2015 from other IMDEA projects.

New commercial equipment

UV-Infrared spectroscopy (IR). To quickly determine the presence or absence of functional ,

inorganic and organic groups on the surface of magnetic nanoparticles.

Bruker FT -IR ALPHA system with ATR module, frequency range : 25000 - 50 cm -1, and fast and

accurate measurement system of solid and liquid samples.

Just ordered (June 2016).

New home-made equipment

Induction

electromagnet

Thermometer

Magnetic fluid

Heat capacity [W/grFe] = SAR = Area x frequency

AC calorimetry AC magnetometry Appl. Phys. Lett. 101, 062413 (2012);

J. Phys. Chem. C 119, 15698 (2015) to be published (2016)

pick-up coils

magnetic fluid

1 H

z –

0,5

MH

z

0– 6

0 m

T

AC

in

du

ctor

SAR= specific absorption rate dT/dt

Appl. Phys. Rev. 2, 041302 (2015)

New home-made equipment

Induction

electromagnet

Thermometer

Magnetic fluid

Heat capacity [W/grFe] = SAR = Area x frequency

AC calorimetry AC magnetometry

to be published (2016)

pick-up coils

magnetic fluid

1 H

z –

0,5

MH

z

0– 6

0 m

T

AC

in

du

ctor

f < 1 kHz non-hysteretic

f > 10 kHz hysteretic

SAR= specific absorption rate dT/dt

Appl. Phys. Rev. 2, 041302 (2015)

Appl. Phys. Lett. 101, 062413 (2012);

J. Phys. Chem. C 119, 15698 (2015)

g-force induced giant efficiency of nanoparticles

internalization into living cells

Scientific Reports | 5:15160 | (2015) DOI: 10.1038/srep15160

Direct incubation CMI

5 min.

CMI results in controllable cellular uptake efficiencies at least three orders of magnitude

larger than current procedures. The methodology is easily transferable to any laboratory with

great potential for the development of improved biomedical applications (see video).

GNB-IMDEA / GBE-CSIC/ HM

50 mg/ml IONPs

Centrifugated Mediated Internalization

(CMI) promotes a high uptake of iron

oxide nanoparticles (IONPs) in living cells,

just in a few minutes, and via clathrin-

independent endocytosis pathway

pinned

soft

I + I V V +

lens

Wollastone

prism

/2 plate

HeN

e laser

lens

m0H

a

M||

M

photodiodes

pinned

soft

I + I V V +

lens

Wollastone

prism

/2 plate

HeN

e laser

HeN

e laser

lens

m0H

a

M||

M

photodiodes

Unique experimental set-up that allows to measure simultaneously magneto-resistance (MR) and vectorial-resolved Kerr hysteresis loops (M|| and M) at different applied field angles in the whole angular range.

CIP geometry

I [250mA] // e.a.

Appl. Phys. Lett. 86, 024421 (2014); PRB 92, 220422(R) (2015)

NanoMagLab-IMDEA/LASUAM/

Simultaneous v-Kerr + MR Direct experimental determination of the anisotropic

magnetoresistive effects

Uniaxial magnetic anisotropy system

Appl. Phys. Lett. 104, 202407 (2014)

AIP Advances 6, 055819 (2016)

Interfacial exchange-coupling induced

chiral symmetry breaking of Spin-Orbit effects…

FM/AFM systems

exchange-biased spin-valve

Simultaneous v-Kerr + MR

PRB 92, 220422(R) (2015)

Phys. Rev. B 86, 024421 (2012)

see movie

Rebeca Amaro Leonor de la Cueva David Cabrera

Hyperthermia NPM synthesis

RE-free PMs Spintronic/OMBE

Noelia López Sergio L. de las Heras

Fondo de garantía juvenil

Síntesis de NPs (CoFe2O4 (CFO), Magnetita Fe3O4)

Model systems: NEXMAG (Mn-based alloys), SOGRAPH (gr-based spin-orbitronics),

SKYTRON (skyrmion-based spintronics), …

C- Sistema v-M(R)OKE de temperatura variable (5 K- 500K), para poder correlacionar

propiedades magnéticas y magnetoresistivas durante transiciones magnéticas.

D- Magnetometría para estudiar dinámica magnética de nanoparticulas magnéticas

dispersas en medios acuosos o internalizadas en matrices biológicas (células o

tejidos) a través de la medida de los ciclos de imanación en condiciones dinámicas,

procesos íntimamente relacionados con la disipación térmica de las nanopárticulas en

régimen dinámico.

E- Generador portátil de campos magnéticos alternos sintonizable en frecuencia

(hasta 200 kHz) y amplitud de campo (hasta 60 mT), para estudios in-vitro e in-vivo de

hipertermia magnética.