2013 CRS Annual Meeting & Exposition Registration Brochure

40th Annual Meeting & Exposition of the Controlled Release Society

July 21–24, 2013Hawaii Convention CenterHonolulu, Hawaii, U.S.A.

Emerging Challenges for Global Delivery

Program Team

2013 Annual Meeting Program Planning Committee

Chair: Mark Saltzman, Yale University, U.S.A.

Deputy Chair: Ick Chan Kwon, KIST, Korea

Marcel Bally, British Columbia Cancer Research Centre, Canada

Marcus Brewster, Johnson & Johnson, Belgium

Sarah Eccleston, Aptuit Ltd., United Kingdom

Chuck Frey, Coating Place Inc., U.S.A.

Justin Hanes, Johns Hopkins University, U.S.A.

Hideyoshi Harashima, Hokkaido University, Japan

Nicole Papen-Botterhuis, TNO, The Netherlands

Joshua Reineke, Wayne State University, U.S.A.

Christian Seiler, Merck Sharp & Dohme, United Kingdom

Say Aloha to the CRS Annual MeetingTh e Controlled Release Society is excited to meet in Honolulu, Hawaii, U.S.A., a Pacifi c gateway to Asia and the Pacifi c Rim. Register now to join your delivery science colleagues at the 40th Annual Meeting & Exposition. Discover the latest on all the hottest topics in de-livery science and technology, including ocular and oral delivery, drug combinations, nano-technology, interspecies variability, nutraceuticals, peptide and protein delivery, and more.

See you on the island!

Why Hawaii?Hawaii is a unique location and its Aloha spirit are perfect for research, international networking, and business development.

Hawaii off ers:An Excellent Location. Hawaii is positioned as a center of commerce with global appeal. Th e emerging markets of China, India, and other Asian and Pacifi c Rim countries off er huge potential in delivery science.

Th e Chance to Reach All CRS Members. CRS is truly an international society, with members representing more than 50 countries.

A Price Th at is Right. Honolulu is considered less expensive than most major U.S. convention cities.

Worldwide Appeal. Th e exceptional year-round climate and hospitality make Hawaii the perfect meeting place. Th e islands are tropically exotic, yet professional in how business is done.

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Photo CreditsCover: Aerial view of Honolulu Convention Center, ©David Cornwell: ©shutterstock.comPages 3, 8, 10: ©istockphoto.comPages 3, 27, Mail panel: ©Honolulu Tourism Authority, Tor Johnson

Invitation from the President

Kazunori KataokaPresident

Controlled Release Society

About the Society

Th e Controlled Release Society is the premier international, multidisciplinary society dedicated to delivery science and technology. In the constantly and quickly expanding fi eld of delivery science, keeping up with the latest scientifi c research and technological breakthroughs is crucial. CRS serves members from industry, academia, and government in more than 50 countries worldwide by providing innovative research, targeted networking, and career advancement. Access a diverse, stimulating international society that is dedicated to this multidisciplinary fi eld.

“Th e beautiful island of Hawaii will off er

the perfect location to learn about the latest

in delivery science while making vital

business connections. I look forward to

seeing all of you in Honolulu.”

www.controlledreleasesociety.org/meeting 3

Table of Contents

Schedule-at-a-Glance .................................................. 4Program Highlights ..................................................... 6CRS Innovation Sunday ............................................. 11Workshops ................................................................. 16CRS Foundation ......................................................... 20Networking Opportunities ....................................... 20Exposition .................................................................... 22Sponsorship ............................................................... 23Registration Information ........................................... 23Convention Center & Hotel Information .................. 26The Islands Are Calling: Exotic, Tropical Hawaii ....... 27

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Schedule-at-a-Glance Saturday, July 20

07:00 – 15:00 CRS Registration Open

07:00 – 17:00 Speaker Preparation Room Open

08:00 – 17:00 Educational Workshops

08:00 – 17:00 Young Scientist Workshop

08:00 – 17:00 Exhibit Set-up

Sunday, July 21



08:00 – 12:00 Young Scientist Workshop

08:00 – 12:00 Educational Workshops

08:00 – 14:00 Exhibit and Poster Set-up

09:00 – 12:30 Technology Forums

11:30 – 12:30 First Timers’ Meeting

12:30 – 14:00 Young Scientist Roundtable

13:00 – 15:10 Soapbox Sessions

15:30 – 17:30 Industry Roundtable

17:30 – 19:30 Exposition Grand Opening & Welcome Reception

Monday, July 22

07:00 – 08:00 Get Up! Get Educated!



08:00 – 09:30 CRS Opening Session

09:30 – 10:30 Poster Session 1 (authors present)

09:30 – 10:30 Exposition Open – Meet with Exhibitors

09:30 – 17:30 Exposition Hall Open

09:30 – 17:30 Poster Viewing

10:30 – 12:00 Scientific Sessions

11:30 – 13:30 Mentor/Protégé Meet and Greet


13:30 – 14:45 Plenary Session


16:30 – 17:30 Poster and Exposition Happy Hour – Meet with Exhibitors

17:30 – 18:30 Preclinical Sciences & Animal Health Get-Together

21:00 – 22:30 Young Scientist Networking Event

Tuesday, July 23

07:00 – 08:00 Get Up! Get Educated!

07:00 – 16:00 Poster Viewing






09:30 – 16:00 Exposition Hall Open


12:00 – 13:30 C&DP Luncheon




16:00 – 17:00 Poster Take-down

16:00 – 17:30 Roundtables and Focus Groups

16:00 – 18:00 Exhibit Take-down

18:30 – 22:00 CRS President’s Banquet

Wednesday, July 24





Program Highlights

Access the latest in delivery science and technology through a wide variety of learning opportunities, including CRS Innovation Sunday, featured plenary sessions, educational workshops, interactive roundtables, mini-symposia, and more. You will have the chance to discover the latest findings in your area of delivery science, plus expand your knowledge of and apply technologies from other areas.

Exposition Grand Opening & Welcome Reception

The official welcome to the CRS Annual Meeting and Exposition! Join your colleagues and exhibiting companies for an evening of appetizers and beverages, along with the chance to connect one-on-one with your fellow scientists and company representatives.

CRS Opening Session

The opening session will feature a welcome by President Kazunori Kataoka and the presentation of the 2013 Fellows awards, along with the CRS T. Nagai Postdoctoral Research Award and the Young Investigator Award. The session will conclude with a lively panel discussion organized by our College of Fellows.

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“It is the best meeting for overall drug delivery science and technology.”


Plenary Sessions

Headlining this year’s program are plenary lectures on the successful launching of new technology in immunology, the application of nanotechnology, and insights from within the venture capital world. These lectures offer a high-level look at technology and paths to bringing it to practical use.

Electrostatic Nanolayer Delivery Platforms: From Macro- to NanopharmaciesThe electrostatic layer-by-layer process is a simple and elegant method of constructing highly tailored ultrathin polymer and organic–inorganic composite thin films to deliver proteins and biologic drugs in a highly tunable way. This approach can be adapted to achieve various goals, including releasing drugs in specific regions, increasing the half-life of the particle in the bloodstream, and preventing recognition of the particle as a foreign body. It is also possible to synthesize extremely long strands of RNA for cellular delivery, yielding active siRNA strands at significant doses.

Hype and Hope: A View from a Venture Capitalist Josh Wolfe provides a venture capital investor perspective on commercializing scientific breakthroughs, raising capital, recruiting talent, and building a high-growth high-tech venture. He dispels myths and shares insider views on the high-stakes, risky, and competitive world of venture investing. How can you secure non-dilutive funding? What are the key terms to seek or be wary of when negotiating a deal? What are the new and emerging trends VCs are pursuing, and where are they shunning opportunities?

Human B-Lymphocytes as a Source of High-Affinity, Really Fully Human AntibodiesProducing antibody medicines through the hybridoma method in which transgenic mice are grafted with human antibody genes results in low-affinity antibodies that are not fully human. In contrast, human blood B-lymphocytes are activated through natural immune reactions. They are stimulated repeatedly with a small amount of antigen, so only those producing high-affinity antibodies are activated. Thus, human lymphocytes are an excellent source of high-affinity, really fully human antibodies. This session covers Evec’s antibody production technology using Epstein-Barr virus and its experience in license negotiations.

Wednesday, July 24 09:45 – 11:00

Paula T. HammondDavid H. Koch Professor of Engineering, Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, U.S.A.

Tuesday, July 23 08:00 – 09:30

Josh WolfeFounding Partner and Managing Director, Lux Capital, U.S.A.

Monday, July 22 13:30 – 14:45Kenzo TakadaChairman and Founder, Evec, Inc., Professor Emeritus, Hokkaido University, Japan

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Invited Speakers

The 40th Annual Meeting & Exposition of the Controlled Release Society is pleased to announce the following invited speakers. Topics and speakers are subject to change.

Scientific SessionsScientific Sessions form the core of the annual meeting and are focused on various aspects within the extensive scope of controlled release and delivery. The 20 sessions highlight the latest information on bioactives, consumer & diversified products, and preclinical sciences & animal health. Each session features an invited speaker and includes four addi-tional speakers to round out the session. These sessions offer an exciting lineup of top scientists representing the con-tinuum of delivery science and technology. Full session de-scriptions and speakers can be found online.

Challenges Around Brain Delivery: Sampling Site Issues and Interspecies Extrapolations Margareta Hammarlund-Udenaes, Uppsala University, Sweden

Drug Delivery for Developing Countries/Global Challenges Kim Woodrow, University of Washington, U.S.A.

Drug Targeting, Pharmacokinetics and Biodistribution: Differences Between Species Jim Klostergaard, University of Texas, M.D. Anderson Cancer Center, U.S.A.

Emerging Technologies Dan Luo, Cornell University, U.S.A.

Food, Nutraceuticals, and Personalized Diet Martin Kussmann, Nestlé Institute of Health Sciences SA, Switzerland

Imaging and Characterization Techniques for Drug Delivery: Systems and Targeted Drug Delivery Karsten Mäder, Martin-Luther University Halle-Wittenberg, Germany

Micro- and Nanoparticle Design David Weitz, Harvard University, U.S.A.

Modern Agriculture and Aquaculture Speaker to be named

Session Information


Oral CR—Pharmaceutical Formulations, Technologies and Development Strategies Peter Timmins, Bristol-Myers Squibb, United Kingdom

Oral CR—Predictive Tools (In Vitro/In Vivo/In Silico) Sandra Klein, UNI Greifswald, Germany

Parenteral Sustained Release Drug Delivery Steven Schwendeman, University of Michigan, U.S.A.

Peptide and Protein Delivery Tarek Fahmy, Yale University, U.S.A.

Personal and Home Care Jiten Dihora, Procter & Gamble, U.S.A.

Processing Technology/Manufacturability Speaker to be named

Regional Delivery: Challenges in Ocular Delivery and Pulmonary Delivery Samir Patel, Clearside Biomedical, U.S.A.

Rising Suns in Asia Yukio Nagasaki, University of Tsukuba, Japan

RNAi and DNA Delivery Chae-Ok Yun, Hanyang University, Korea

Smart Building and Construction Materials and Coatings Henk Jonkers, Delft University of Technology, The Netherlands

Solubilization Technology—A Key Enabler for the Delivery of Poorly Soluble Drugs Ravi Shanker, Pfizer, U.S.A.

Topical/Transdermal Drug Delivery Rainer Müller, Freie University Berlin, Germany

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Mini-Symposia

Mini-symposia offer in-depth knowledge into a specific area of delivery science and technology, featuring three invited speakers sharing their research on the topic. Topic descriptions can be found on the CRS website. Speakers subject to change.

Breakthrough Technologies in Drug Delivery Systems from AsiaKwangmeyung Kim, KIST, KoreaHirofumi Takeuchi, Gifu Pharmaceutical University, JapanZhiyuan Zhong, Soochow University, China

Drug Combination ProductsCharlie Boone, University of Toronto, CanadaLawrence Mayer, Celator Pharmaceuticals Corporation, CanadaLiangfang Zhang, University of California, U.S.A.

Energy: Problems within the Industry that Controlled Delivery Can Solve

Anne Dalager Dyrli, RESMAN AS, NorwayJo Darkwa, University of Nottingham Ningbo, ChinaJames Oxley, Southwest Research Institute, U.S.A.

Hybrid Groups: Bridging the Gap Between Industry and Academia

Karimah Es Sabar, Center for Drug Research and Development, CanadaBert Klebl, The Lead Discovery Center at Max Planck, GermanySpeaker to be named

Nanoparticles and CancerMichelle Bradbury, Memorial Sloan-Kettering Cancer Center and Sloan-Kettering Institute, U.S.A.Peter Senter, Seattle Genetics Inc., U.S.A.Sonke Svenson, Cerulean Pharma Inc., U.S.A.

“A ‘must attend’ meeting for anyone in the drug delivery field.”


Sunday, July 21

CRS Innovation Sunday is all about the business of delivery science, taking innovative ideas and technologies into the commercial sector. All of these sessions give you new, important information on companies and technologies as well as great opportunities for networking face-to-face. This is the start of the CRS Annual Meeting program—don’t miss it!

Technology Forums (formerly Releasing Technology Workshops)

Are you interested in learning more about a company’s research and products? Interested in a new technology from the company that developed it? Open to all registered attendees, Technology Forums give you the opportunity to gain in-depth information presented by the hosting company. Presentation titles, details, and speakers are posted on the CRS Innovation Sunday webpage for these participating companies:

CapsugelCatalentCIMA LabsColorcon Inc.Medimetrics

Mott CorporationOctoPlusParticle Sciences, Inc.SOTAX Corporation

Soapbox Sessions

Co-sponsored by Catalent

What’s new in delivery science? Come to the program where presenters “get up on their soapbox” to give you a quick glimpse of some of the most innovative technologies and products in development today. Linger to network with the presenters as you enjoy refreshments, with thanks to our sponsor. Soapbox applications will be received and reviewed until the session is full. Watch the CRS Innovation Sunday webpage for topics and presenters.

Industry Roundtable: Global Perspectives on Emerging and Established Delivery MarketsA global panel of business development and R&D executives from Asia, Europe, and North America will provide insight on the latest trends, challenges, and needs they see in delivery science. CRS welcomes your audience participation in this session that is all about the international business of delivery science, offering a mix of presentations, panels, and case studies.

Exposition Grand Opening & Welcome ReceptionJoin your colleagues and exhibiting companies for the official welcome to the CRS Annual Meeting & Exposition. The Exposition Hall will be brimming with new products, services, and innovations from CRS exhibitors, including new companies in the Asia Pacific Pavilion. Take this opportunity to enjoy light hors d’oeuvres, view scientific posters, and connect one-on-one with your fellow scientists and company representatives.

CRS Innovation Sunday Delivery Science Meets Business Opportunities

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Roundtable Discussions

Join your colleagues for these in-depth interactive sessions where a panel of experts will share their findings and opinions, creating an extended discussion on focused topics. This is a great opportunity to connect with colleagues with similar interests.

Note that the focus group meetings follow the Nanomedicine, Ocular and Oral Drug Delivery roundtable discussions.

Nanomedicine Roundtable—Challenges Associated with Commercialization of Nanomedicines

Tuesday, July 23

Chaired by Christine Allen, University of Toronto, Canada, and Marcel Bally, British Columbia Cancer Research Centre, Canada

Nanomedicines have the potential to transform healthcare, improving patient outcomes worldwide. However, their translation from bench to bedside has been challenging. Significant hurdles need to be overcome to move nanomedicines developed in the preclinical setting to the market. Successful commercialization of nanomedicines requires a multidisciplinary approach that brings together scientists, clinicians, and business professionals. World experts in the nanomedicine field will share their experiences related to the highs and lows of nanomedicine development and commercialization.

Ocular Drug Delivery Roundtable—Novel Biomaterials for Ocular Drug Delivery

Tuesday, July 23

Chaired by Ruiwen Shi, Allergan Inc., U.S.A., and Clive G. Wilson, University of Strathclyde, United Kingdom

Eye diseases such as glaucoma, age-related macular degeneration, and diabetic retinopathy are rising at an alarming rate and are leading causes of blindness. Local delivery of therapeutic agents is considered key for effectively treating these diseases while minimizing systemic toxicity. Advances in materials science and engineering have created unprecedented opportunities for the development of intraocular drug delivery systems. This roundtable will discuss the current status of biomaterials used in ocular drug delivery systems and novel materials that are emerging.

“The best opportunity to get in touch with skills of the art of pharmaceutical sciences and to share knowledge with others.”

Oral Drug Delivery Roundtable—Multiparticulate Oral Drug Delivery Systems for Fixed Dose Combinations

Tuesday, July 23

Chaired by Sarah Eccleston, Aptuit Ltd., United Kingdom, and Ali Rajabi-Siahboomi, Colorcon Inc., U.S.A.

Many drug products utilize multiparticulate technologies. This is a key platform technology for delivering multidrug therapies for general use, special patient groups (geriatric and pediatric population), and emerging markets. Regardless of the purpose of the multiparticulate systems, the development process may require careful consideration. Multiparticulate opportunities for fixed dose combinations, including case studies to illustrate challenges and best practices, will be discussed. Hear from industry leaders on this hot topic, and share your experiences during the discussion.

Young Scientist Roundtable—Commercializing Ideas from Academia: Past Lessons and Current Challenges

Sunday, July 21

Chaired by Adam Bohr, Veloxis Pharmaceuticals A/S, Denmark, and Hardik Shah, Alkermes Pharma Ireland Ltd., Ireland

Novel idea, proof of concept, in-depth analysis… At what point are an academic researcher’s results sufficient to start a company or bring a new product to the market? This roundtable will discuss the challenges to develop a business/marketing model while competing with the pharmaceutical industry. It will provide insight into intellectual property, evaluation of business opportunities, licensing, industrial collaborations, and regulatory aspects. Successful entrepreneurs will share their experiences and discuss challenges in commercializing ideas from academia.


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Nanomedicines for Drug Delivery Across Epithelial Barriers: Intestines, Skin, and Lungs

Monday, July 22

Chaired by Prajakta Dandekar Jain, Institute of Chemical Technology, Mumbai, India

Speaker: Claus-Michael Lehr, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany

This session is a must-attend for young scientists and will educate them on how nanoscale drug formulations have an edge over conventional formulations for improved drug delivery across epithelial barriers. Discussion involving experimental evidence will prove the advantage of drug/antigen loaded nanoparticles for targeted therapy of inflammatory bowel diseases, as needle-free vaccines via the dermal route to avoid the need for painful injections, and for delivery across the air-blood barrier while controlling mucociliary and macrophage clearance.

Please indicate your attendance when registering. Complimentary event.

Get Up! Get Educated!

Quality by Design: Systematic Development of Pharmaceutical Products

Tuesday, July 23

Chaired by Joshua Reineke, Wayne State University, U.S.A., and Pirthi Pal Singh, Panacea Biotec Ltd., India

Beyond development of delivery systems, formulation scientists must integrate scientific development along with regulatory requirements. Regulatory agencies monitor the path selected for initial screening, prototype development, process and composition optimization, and stability of drug product in addition to the final developed product. Quality by Design (QbD) ensures the systematic approach to development that begins with predefined objectives and emphasizes process understanding and process control, based on sound science and quality risk management.


CRS serves industry, academia, student, and government affiliations—industry being the largest with 44%


Young Scientist Mentor/Protégé Meet and Greet

Monday, July 22

Organized by the CRS Young Scientist Mentor/Protégé Subcommittee

Are you interested in being a mentor or protégé? Provide your knowledge and encouragement to a young scientist or be the recipient of expertise and experience from academics or industry scientists for your professional and career development. Preregistration for the 2013–2014 CRS Young Scientist Mentorship Program is strongly encouraged. Do not miss this exciting session for the opportunity to meet face-to-face your mentor or protégé.

“Tell me and I forget, teach me and I may remember, involve me and I learn.” – Benjamin Franklin


Posters

CRS Posters and Poster Author Sessions

All scientific posters will be set up and available for viewing Sunday evening during the Exposition Grand Opening & Welcome Reception and all day Monday and Tuesday. Three poster author sessions are scheduled on Monday and Tuesday. One-third of poster authors will be present at each session. CRS will again be offering Poster Snapshots – three-minute audio recordings that provide a summary preview of poster content. The snapshots can be listened to at the attendee’s convenience via the CRS Mobile App. Poster take-down will take place on Tuesday, July 23, 16:00 – 17:00.

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Oral Delivery of Bioactives Using Lipid-Based Drug Delivery Systems

Saturday, July 20 – Sunday, July 21 (1 ½ days)

Chaired by Sarah Hook, University of Otago, New Zealand, and Anette Müllertz, University of Copenhagen, Denmark

The three major challenges in the development of oral delivery systems are poor aqueous solubility of low-molecular “classical” drugs, the development of oral delivery systems for modern biologics, and the development of oral vaccines. In all three areas lipid delivery systems have a lot to offer. This workshop will explore new developments in the formulation and delivery of small-molecular-weight drugs, proteins, and vaccines. Analytical techniques for the development of lipid-based delivery systems will also be included.

Early Regular/OnsiteWorkshop Price (by May 2, 2013) (after May 2, 2013)Regular $525 $625Student/Postdoc $250 $300

Controlled Release Dosage Forms and Product Development Strategy for Expected New Regulatory Trends

Saturday, July 20 (Full day)

Chaired by Yanning Lin and Ubrani Venkataram, Food and Drug Administration, U.S.A.

The FDA expects the application of QbD principles. Speakers will discuss new trends and technology approaches for robust formulations, a development strategy via in vitro–in vivo relationships, the use of spectroscopic methods, and scale-up for the Wurster process. FDA staff will discuss current expectations for regulatory submissions in the Office of Generic Drugs with a focus on application of QbD principles to the product development of controlled release solid oral dosage forms.


WorkshopsEducational Workshops

These workshops offer focused presentations on specific topics by noted speakers and are open to a limited number of participants for an additional fee.


continued

Leadership Workshop for Women in Science


Chaired by Diane Burgess, University of Connecticut, U.S.A.Organized by the CRS Women in Science Task Force

This highly-interactive professional development workshop includes best-practice theory, personal reflection and small group work. Each participant will leave with a clear understanding of their management strengths and challenge. Attendees will also learn how to enhance their ability to lead a team, build a coalition with peers and a better understanding of how to influence “up”. Prior to the course, each participant will be asked to take two online personal assessments. Results from this pre course work will be used to create personalized binders for each participant to use during the workshop.

Registration deadline for this course is July 4, 2013 due to the pre course work.

Early RegularWorkshop Price (by May 2, 2013) (after May 2, 2013)Regular $525 $625Student/Postdoc $250 $300

Taste-Masking Technologies and Formulations: Meeting the Challenges for Bitter Drug Actives


Chaired by Tom Farrell, Colorcon Inc., U.S.A., and Nigel Langley, BASF Corporation, U.S.A.

The workshop will discuss the growing importance and relevance of taste masking in pharmaceutical drug development. Areas such as life-cycle management, pediatric, geriatric, and veterinary medicines will be highlighted. The FDA will provide insight into the current requirements for pediatric medicines. Existing and new technologies for taste masking solid oral dosages and liquid formulations will be described. An open panel discussion will provide attendees an opportunity to debate this important issue.


Educational Workshops (continued)

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Using In Vitro–In Vivo Correlation (IVIVC) to Meet Challenges in Global Delivery

Saturday, July 20 (Afternoon)

Chaired by Tapash Ghosh, ONDQA/CDER/FDA, U.S.A., and Vivian Gray, V. A. Gray Consulting, Inc., U.S.A.

This workshop will provide a stimulus to develop in vitro–in vivo correlations (IVIVC), highlighting the utility of the correlation. A discussion of global expectations for IVIVC will review regulatory guidance and FDA experiences. The key factors in developing the in vitro test and supporting the formulation will be explored, along with case studies of biowaivers using IVIVC. The traditional approach to IVIVC and in vitro–in vivo relationships (IVIVR) using deconvolution will be presented.


Locally Acting Dermal Drug Products: Global Challenges for Development and Registration

Sunday, July 21 (Morning)

Chaired by Tapash Ghosh, ONDQA/CDER/FDA, U.S.A., and Howard Maibach, University of California, U.S.A.

The workshop will bring a sound understanding of topical dermal products across multiple disciplines and multiple sectors. It will also discuss challenges associated with demonstration of bioequivalence for topical products from both new and generic drug perspectives in light of considerations for future regulatory submissions. Alternative and novel technologies for determining bioequivalence of topical drug products as well as the value of in vitro drug release in semisolid dosage forms will also be discussed.


80% of attendees indicated that the most important reason to attend the annual meeting is to learn about new technology


Young Scientist Workshops

The Young Scientist workshops are specifically designed with the interests of young scientists in mind. Young scientists are typically students and early career scientists under the age of 40 years, or those with less than five years’ experi-ence in the field of delivery science.

Young Scientist Workshop I—Fundamentals of Controlled Release Drug Delivery: Physiochemical and Biological Aspects


Chaired by Raid Alany, Kingston University London, United Kingdom, Giorgia Pastorin, National University of Singapore, Singapore, and Zimei Wu, University of Auckland, New Zealand

Whether you are a Ph.D. student, a postdoctoral fellow, or an established researcher, it is vital that you brush up on the fundamentals of the design and performance of innovative controlled release drug delivery systems (DDS). The key physicochemical and biopharmaceutical concepts essential for successful DDS design will be reviewed, and various routes of drug delivery will be com-pared and contrasted. Furthermore, this workshop will shed light on cutting-edge innovations underpinned by the fundamental principles.


“Very good possibility to get an insight into actual topics and talks with key opinion leaders from all over the world.”

Young Scientist Workshop II—Professional and Self Development for Young Scientists and Protégés: Effective Communication

Sunday, July 21 (Morning)

Chaired by Michael Rathbone, International Medical University, Malaysia, and Teresa Virgallito, Microtek Labs Inc., U.S.A.

The workshop will provide young scientists with a training program for developing interpersonal relationships, improving listening skills, teach-ing negotiation skills, resolving conflict, and strengthening assertiveness. Young scientists will be able to improve their communication skills by increasing their awareness, attentiveness, and empathizing capacity, and so facilitate better communication throughout their organization. The work-shop will also focus on intercultural communication. Global communica-tion is essential in today’s international business and academic communities.


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Networking OpportunitiesCRS Connect

As a CRS Annual Meeting attendee, CRS Connect is your premier opportunity to network with colleagues while in Honolulu. As part of the CRS Mobile App, CRS Connect is easily accessible from your mobile phone, tablet, or computer. This networking tool allows you to plan the scientist-to-scientist or business development collaborations you seek at the annual meeting while maintaining your full privacy, as personal contact information is never shared. For instructional information, please visit www.controlledreleasesociety.org/meeting.

First Timers’ Meeting

Plan to attend this special meeting where CRS leaders and seasoned meeting attendees will provide suggestions to help you make the most of your first meeting experience.


CRS FoundationFounded as an educational endowment in 2007, the CRS Foundation honors leaders who have made notable contributions to delivery science and supports the scientific training of its future leadership. Thanks to generous donors, more than $120,000 has been raised for postdoctoral fellowships that expand research and travel opportunities for outstanding young scientists. Please help the Foundation expand its fellowships by giving annually. The next fellowship honors Alexander “Sandy” Florence in 2014.

Donate when you register for the annual meeting.

CRS Foundation Reflections

Sung Wan Kim Postdoctoral Fellowship, 2012–2013: A Year in ReviewYou will see, firsthand, the outcomes of the CRS Foundation’s support. CRS Foundation awardee Tram Dang will present outcomes of her fellowship year engineering high-throughput in vitro systems for the investigation of immunological interaction in the Ali Khademhosseini Laboratory at Brigham and Women’s Hospital, Harvard Medical School.

“Very good meeting for academics to meet pharma.”

Tram Dang


Preclinical Sciences & Animal Health Get-Together

Monday, July 22

Co-Sponsored by Merial

This year’s Get-Together promises to be better than ever! Dr. Marilyn Martinez addresses the question “Why is the beagle the dog of choice for preclinical studies?” Simcyp will describe recent advances in the development of a canine physiologically based pharmacokinetic model to support within- and between-species extrapolations. An enticing discussion will follow. Included in the ticket price are one drink ticket and hors d’oeuvres.

Advance registration and payment required. Ticket price $10.

Young Scientist Networking Event

Monday, July 22

Organized by the Young Scientist Committee

Co-Sponsored by Upsher-Smith Labs and Diurnal Ltd.

Spend an enjoyable evening networking with colleagues when you attend the Young Scientist Networking Event at the world-famous Jimmy Buffett’s at the Beachcomber Restaurant and Honolulu Surfing Museum. Reunite with familiar faces and make new connections as you tour the surfing museum, which includes a premier collection of surfing artifacts, videos, and surf-inspired items. Then enjoy hors d’oeuvres and cocktails in a venue that truly celebrates the people, culture, and incredible natural wonders of Hawaii.


C&DP Division Luncheon

Tuesday, July 23

Co-Sponsored by The Coating Place, Fleet Laboratories, and Ronald T. Dodge Co.

Join your fellow Consumer & Diversified Products Division members for this networking buffet luncheon at the Hawaii Convention Center. All attendees interested in C&DP are welcome to attend.


CRS President’s Banquet

Get into the Aloha Spirit by attending this year’s President’s Banquet to be held at the beautiful, tropical Hilton Hawaiian Village. The evening will feature scientific highlights from CRS chapters showcasing their recent achievements. You will enjoy a sumptuous dinner reflecting the Hawaiian Islands’ cuisine and culture. Experience the flavors, sights, and sounds of Hawaii while meeting with old friends, creating new friendships, and celebrating a successful CRS Annual Meeting!


“High-quality contacts and networking.”

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ExpositionExposition Hall Activities

Come to the Exposition Hall for discovery, solutions, opportunities, and refreshments! Kicking off with the Sunday evening Exposition Grand Opening & Welcome Reception, the Exposition/Poster Hall will also be open Monday and Tuesday as the central hub for poster viewing, program breaks, and refreshments. Be sure to thank the CRS Café Sponsors (*) for providing complimentary beverages. NEW! Stop by the Asia Pacific Pavilion to meet first-time exhibiting companies from the Asia Pacific region.

3M Drug Delivery Systems

Advanced Polymer Materials Inc.

Agilent Technologies

Asahi Kasei America

*Avanti Polar Lipids

BASF

Bend Research Inc.

Catalent

CIMA Labs

Colorcon Inc.

Corden Pharma

CoSci Med-Tech Co., Ltd.

*Covaris

Dissolution Technologies

Drug Delivery Partnerships

Drug Development & Delivery

DURECT Corp./Lactel Absorbable Polymers

Elsevier

EMD Millipore

Evonik Degussa Corporation Pharma Polymers

Freund-Vector Corp.

Glatt Air Techniques, Inc.

Halozyme Therapeutics

*Hovione

*Lipoid

Lubrizol

Medimetrics

The Methodist Hospital Research Institute

Michelson Prize & Grants

NanoSight

Nisso America Inc.

NOF Corp

Northern Lipids Inc.

Novozymes Biopharma

*Octoplus NV

ONdrugDelivery Magazine

Particle Sciences, Inc.

Partnership Opportunities in Drug Delivery – PODD

Patheon

Pharmaceutical Technology

PharmaCircle

Polymun Scientific Immunbiologische Forschung GmbH

PolyPeptide Group

PolySciTech Div Akina, Inc.

Purac Biomaterials

Saint-Gobain Performance Plastics

Scintipharma Inc.

Sekisui Medical Co., Ltd.

Simulations Plus

Sirius Analytical

SkyePharma

SOTAX Corporation

Southwest Research Institute

Springer

Surface Measurement Systems

*Technology Catalysts

Texture Technologies Corp.

Wyatt Technology


SponsorshipSponsors Make It Happen

Many of the annual meeting events are possible only through the generosity of sponsors. Please join CRS in thanking the following 2013 sponsors, current as of February 12, 2013:

Registration Options

➤ Register online at www.controlledreleasesociety.org/meeting

➤ Print and complete the registration form at www.controlledreleasesociety.org/meeting

2013 CRS Registration Fees

All CRS Annual Meeting & Exposition registration fees are in U.S. dollars (USD). Early Regular/OnsiteRegistration Classification (by May 2, 2013) (after May 2, 2013)Member $845 $1,045Student Member $300 $390Postdoc Member $345 $435Meeting + Membership

Registration + Regular Membership $998 $1,198Registration + Student Membership $352 $442Registration + Postdoc Membership $407 $497

Nonmember $999 $1199Student/Postdoc Nonmember $395 $485Single Day $675 $725(Sunday, Monday, Tuesday, Wednesday)

Registration InformationAnnual Meeting Registration

3M Drug Delivery Systems

Advanced Polymer Materials Inc.

Aptalis Pharmaceutical Technologies

Avanti Polar Lipids

Catalent

The Coating Place

Colorcon, Inc.

CoSci Med-Tech Co., Ltd.

Covaris

Diurnal Ltd

Elsevier

Fleet Laboratories

Hovione

Lipoid LLC

Merial

Mylan Technologies Inc.

The Nagai Foundation Tokyo

OctoPlus

Patheon

PharmaCircle

PolySciTech div of Akina, Inc

Ronald T. Dodge Co.

Springer

Technology Catalysts International

Upsher-Smith Labs

Interested in Exhibiting or Sponsorship?

Connect with the CRS international delivery science community. Contact Debby Woodard, Business Development

continued

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Annual meeting registration* includes access to the following:

*Does not include single-day registrations

Tickets must be purchased for all educational workshops, Young Scientist Networking Evening, CRS President’s Banquet, Preclinical Sciences & Animal Health Get-Together, and C&DP Luncheon.

Please indicate your attendance for the free workshops and events scheduled throughout the week so that we may plan accordingly. Tickets are limited for some events, and early registration is recommended. The deadline for early annual meeting registration is May 2, 2013.

Exhibitor Registration Each exhibiting company is entitled to a specified number of complimentary annual meeting registrations based on exhibit size. Please see the Exhibitor Checklist on the CRS Annual Meeting & Exposition website for more information and to register each exhibitor individually with the customized form.

Complimentary allotment:

Space Complimentary Registrations10 x 10 Foot Booth 2 Full Program + 2 Exhibit Personnel 10 x 20 Foot Booth 4 Full Program + 3 Exhibit Personnel6 x 2 Foot Tabletop 1 Full Program + 1 Exhibit Personnel

Rates for exhibitors beyond the complimentary allotment are:

Early Regular/Onsite (by May 2, 2013) (after May 2, 2013)Exhibitor Full Program $765 $995Exhibitor Personnel $345 $345Add CRS Membership $169 $169

Member RatesDiscounted member rates apply only to current paid members of the Controlled Release Society. If you are not a current member of CRS, renew or join when you register to take advantage of everything that CRS membership has to offer.

Full-time Student/Postdoc RatesFull-time students and postdocs qualify for discounted registration rates. Proof of graduate student or postdoctoral research status will be required when registering for the annual meeting.

Abstracts (available June 21, 2013)

CRS Connect

CRS Innovation Sunday Sessions

Exposition

Focus Groups

Exposition Grand Opening & Welcome Reception

Get Up! Get Educated! Sessions

Podium and Poster Scientific Sessions

Technology Forums

Roundtable Discussions

Soapbox Sessions

Young Scientist Events (except as noted)

Registration Information (continued)

“Excellent, and improving all the time.”


Cancellation PolicyCancellations must be made in writing and be received by CRS no later than May 16, 2013. Cancellations received by this date are subject to a $100 processing fee. Ticketed events will be fully refunded before this date. CRS Annual Meeting & Exposition registration and ticketed event cancellations received after May 16, 2013, are not subject to refund.

PaymentPayment must accompany your registration. Registrations will be charged in U.S. dollars. Payment vouchers or purchase orders are not considered payment. Payment options are:

Credit card: Pay when registering online. Alternatively, fax (+1.651.454.0766) or mail (see address below) the completed form with credit card information. For security reasons, we do not recommend sending your credit card information

via e-mail.

Check: Mail the completed form and check payment to:

CRS Meeting Registration3340 Pilot Knob RoadSt. Paul, MN 55121 U.S.A.

Attire and WeatherBusiness casual is the recommended dress for the CRS Annual Meeting & Exposition. Comfortable walking shoes and casual, light-weight clothing are recommended for after-meeting activities. Weather in Hawaii is consistent, with only minor changes in temperature throughout the year. The average mid-July high temperature in Honolulu is 88°F (31.1°C). The average evening low tem-perature is 73°F (22.8°C).

Emergency InformationIf you have a medical condition that CRS should be aware of during the meeting, please fax your information to CRS Annual Meeting & Exposition,

-ceived no later than June 1, 2013, and is optional. Your information will not be shared with anyone, except in case of emergency, and then only with emergency personnel.

ADA/Special RequestsFor full and equal enjoyment of the CRS Annual Meeting & Exposition, please tell us of any special requirements you may have in the “Special Accommoda-tion” area of the registration form, and a CRS staff person will contact you to further discuss your needs.

Program ModificationsAll information is subject to change without notice.

Official LanguageEnglish is the official language of the CRS Annual Meeting & Exposition.

Photo ReleaseMany photographs will be taken throughout the CRS Annual Meeting & Exposition and are used in CRS electronic and printed promotional materials during the meeting and after it has concluded. By virtue of your attendance, you agree to the Controlled Release Society’s use of your likeness in said pro-motional media.

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Convention Center & CRS Hotel InformationHawaii Convention Center

All scientific sessions, poster sessions, the exposition, and the welcome reception will take place at the Hawaii Convention Center.

Please consult the annual meeting program guide for venue locations for all social events.

Hawaii Convention Center1801 Kalakaua AvenueHonolulu, HI 96815 U.S.A.

CRS Hotel

CRS has reserved a block of rooms at the Hilton Hawaiian Village, at discounted rates. Detailed hotel information and booking instructions for reserving rooms online or by telephone can be found on the CRS Annual Meeting & Exposition website, www.controlledreleasesociety.org/meeting.

Reservation Deadline: June 19, 2013

All hotel rates are in U.S. dollars (USD). Tax on guest rooms is presently 13.962% (subject to change). CRS discounted room rates are available three days before and after annual meeting dates, based on availability. The Hilton Hawaiian Village is very busy after the CRS Annual Meeting. If possible, the Hilton recommends booking holiday time before the annual meeting. Regardless, book early to ensure availability, as summer is one of Honolulu’s busiest times of the year!

Hilton Hawaiian Village— CRS Headquarters Hotel2005 Kalia Road Honolulu, HI 96815 U.S.A.Telephone: +1.808.949.4321Toll-free U.S.A./Canada: +1.800.445.8667

Room Types and Rates*Resort View $229 Single or Double occupancyPartial Ocean View $249 Single or Double occupancyOcean View $269 Single or Double occupancyRainbow Tower Ocean View $299 Single or Double occupancyRainbow Tower Ocean Front $329 Single or Double occupancy

*Rates do not include tax. All rooms come with 2 double beds or 1 king bed. Please

call the Hilton Hawaiian Village for other available room types/suites for which

CRS discounted rates may be applied.


The beautiful city of Honolulu lies on the island of Oahu, part of the chain of islands that make up Hawaii. Honolulu offers the pristine beaches and waters of Waikiki, historic landmarks, world-class shopping, a flourishing cultural scene, and a variety of dining op-tions. Climb Diamond Head, visit Pearl Harbor, snorkel at Hanauma Bay, or simply swim in the warm waters of the Pacific while enjoying your time in paradise.

Getting to HawaiiHonolulu International Airport (HNL) on Oahu is Hawaii’s major airport, serving as the entry point for most of Hawaii’s visitors. All 23 major U.S.A. carriers and 16 international carriers serve Oahu, so you can get there from just about anywhere. Honolulu Interna-tional Airport is conveniently located 9 miles (14.4 km) west of Waikiki Beach, 4 miles (6.4 km) west of Central Honolulu, and 7.5 miles (12 km) west of the Hawaii Convention Center.

International TravelThe U.S. Department of State encourages you to apply for your visa as soon as possible. The U.S. government is working to expedite visa processing; however, visas can take up to three months to obtain, so we encourage you to plan ahead to avoid any delays. The pro-cess of applying for your visa may have changed from the last time you applied or may take longer. If you have any difficulty obtaining a visa for the meeting, visit www.controlledre-leasesociety.org/meetings/annual/travel/ for more details. Letters of invitation are provided to attendees from outside the U.S.A. after they have registered for the meeting.

The Islands Are Calling: Exotic, Tropical Hawaii

Although the CRS Annual Meeting is conducted in English,

CRS has provided introductory websites in additional languages

for your convenience: http://crs2013.hawaiiconvention.com

Controlled Release Society3340 Pilot Knob RoadSt. Paul, MN 55121United States of America

The Forefront of Delivery Science and Technology

40th Annual Meeting & Exposition of the Controlled Release Society

Emerging Challenges for Global Delivery

➤ Register Now! July 21 – 24, 2013

Hawaii Convention Center Honolulu, Hawaii, U.S.A.

2013 CRS Annual Meeting & Exposition Registration Brochure

Documents

Transcript of 2013 CRS Annual Meeting & Exposition Registration Brochure