2012 11-08-3 d-printing-event-ceramics-medical
Transcript of 2012 11-08-3 d-printing-event-ceramics-medical
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Biomedical applications for Additive Manufacturing
le centre collectif de l’industrie technologique belgeThe Collective Centre of the Belgian Technology Industry
Biomedical applications for Additive Manufacturing
Additive Manufacturing for Ceramic parts
ESMA – 8th of Novembre 2012
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Sirris AM&RP capacities - competencies
• Laser sintering of polymeric powder (PA,…): P360 – P390• Objet Connex 500: bi-material
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• Objet Connex 500: bi-material• Electron Beam Melting (Arcam A2)• Hybrid SLA system (Optoform)
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Custom medical implants, a necessity?
Yes, it will work. But ….
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Next generation pre-operative manufactured implants:
• Custom implant manufacture :
• CT-Scan• CAD File of the patient is produced• Engineer + Surgeon 3D implant approved• FEM analysis (when needed)• Custom manufacturing (low cost)• Surgery
The utility of Additive Manufacturing technologies
in the medical field
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• Surgery• Follow up
CENG
[Sirris ADD]
[Sirris ADD][Sirris ADD]
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Medical Additive Manufacturing Software:
ADD capacities & competencies
• Materialise: Mimics• Materialise: 3matic• Marcam: Autofab• Able Software Corp: 3D Doctor• Medicim: Maxilim
ProEngineer
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• ProEngineer• New: Lenexa: Analyze• New: Brisbane: Anatomics• (…)
[Mimics & 3-matic - Materialise]
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The utility of Rapid Prototyping / Manufacturing in
the medical field
Trends in biocompatible materials used in Rapid Prototyping / Manufacturing:
Metals:• Titanium (Ti6Al4V)• Ti-alloys• Stainless steel• Shape memory alloys (Ni-Ti) – in research• Noble materials (Gold)
…
Polymers:• PTFE (Polytetrafluoroethylene)• PMMA (Polymethyl methaacrylate)• PE (Polyethylene)• PEEK• PEKK• … others, too but not implantable
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• Noble materials (Gold)• …
Ceramics:• Hydroxyapatite (HAP)• Zirconia• Tricalcium phosphate (TCP)• Alumine• …
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• … others, too but not implantable
Others:• Hydrogels + Human cells
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The utility of Rapid Prototyping / Manufacturing in
the medical field
Leading applications:
• Pre-surgical planning:
• Custom implant manufacture[Arcam & Objet technology]
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• Physician to physician communication
• Powerful patient presentation tool
• Medical student/resident education
• 3D Surface Scanning/Custom Prosthesis Design
• Patient-custom surgical guides (cutting & placement)
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[Z. Corp Medical Modeling Solutions]
[Z. Corp Medical Modeling Solutions]
[Sirris ADD]
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Leading applications:
• Pre-surgical planning:
• Implant pre-contouring• Screw trajectory• Screw selection/location• Instrument selection• Technique rehearsal• Surgical guides testing
“No matter how good our 3-D graphics are, there isnothing like a model in your hands . . .”
The utility of Rapid Prototyping / Manufacturing in
the medical field
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• Surgical guides testing
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[Objet]
[Objet]
[Objet]
[Sirris ADD]
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Leading applications:
• Pre-surgical planning advantages:
• Significantly reduces O.R. time• Lowers cost• Reduces O.R. team fatigue
• Enhances patient outcomes• Reduces “re-do” procedures
The utility of Rapid Prototyping / Manufacturing in
the medical field
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• Reduces “re-do” procedures• Minimizes size of incisions• Speeds recovery time• Improves anatomical alignment• Enables multiple procedure rehearsals
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[Z. Corp Medical Modeling Solutions]
[Case study: The Alfred Hospital, Melbourne, Australia]
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Medical Field: Application fields
Leading applications:
• Physician to physician communication• Powerful patient presentation tool• Medical student/resident education• Custom Prosthesis Design• Complex parts manufacturing
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[Sirris ADD]
[Sirris ADD] [Sirris ADD][Sirris ADD]
[Sirris ADD]
[Sirris ADD]
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Medical Field: CASE STUDIES @ SIRRIS
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0,5mm
[Sirris ADD] [Sirris ADD] [Sirris ADD]
[Sirris ADD] [Sirris ADD]
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Medical Field: CASE STUDIES in the world
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[Dr J. Poukens - UHasselt]
[Walter Reed Army Medical Center, Washington DC, USA ]
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Medical Field: CASE STUDIES in the world
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World’s first total mandible implant in Titanium
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[UHasselt, Layerwise, Xilloc, Sirris, CamBioceramics, Orbis Medisch Centrum, Xios, KUL]
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World’s first total mandible implant in Titanium
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[UHasselt, Layerwise, Xilloc, Sirris, CamBioceramics, Orbis Medisch Centrum, Xios, KUL]
Hypoglossal
Lingual
Inferior alveolar
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Towards newly designed implants
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[Butscher A., et al., Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing. Acta Biomater (2010)]
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Towards newly designed implants
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Ti6Al4V: E(GPa) = 110 !
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Towards newly designed implants
Case study: Femoral & Total hip implants
• Tomorrow: Custom-fit femoral implants & adapted Young’s modulus
• Patient custom-fit implants• Better distribution of the stresses• Reducing stress-shielding• Reducing micro-motion between bone & sinkage• Surface roughness for strong fixation• Hydroxyapatite coating eased up• Complex biodegradable scaffolds combining HAP & βTCP
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• Complex biodegradable scaffolds combining HAP & βTCP
+ +
[Sirris - ADD]
[Sirris - ADD]
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The future of bio-manufacturing…not so far away!
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Additive Manufacturing: Organ printing
[Wake Forest University School of Medicine][Karolinska Institute in Stockholm ][Wake Forest University School of Medicine]
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[Wake Forest University School of Medicine]
[Wake Forest University School of Medicine][Karolinska Institute in Stockholm ][Wake Forest University School of Medicine]
[University of Manchester - UK]
[Wake Forest University School of Medicine]
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« Medical Additive Manufacturing & Rapid Prototyping »
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« Medical Additive Manufacturing & Rapid Prototyping »
« Sirris »
© sirris 2012 Charleroi | www.sirris.be | [email protected] | 15/11/2012
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Sirris Additive Manufacturing: Contact
Carsten ENGEL
Biomedical EngineerDepartment of Additive Manufacturing
Mail: [email protected]: +32 498 91 94 50Skype: Carsten-Engel
22© sirris 2012 Charleroi | www.sirris.be | [email protected] |
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15/11/2012
Skype: Carsten-Engel
SIRRISRue Auguste Piccard, 20B-6041 GOSSELIES BELGIUMhttp://www.sirris.be