DR SAKINA ,MBBS,M.D SENIOR LECTURER ,MSU

FUNCTIONS OF CSF

FORMATION & COMPOSITION

Characteristics of normal CSF

COMPOSITION & NORMAL RANGES

COMPOSITION & NORMAL RANGES

Clinical Application of CSF Examination

Routine Lab Tests

CSF-PRESSURE

CSF-PRESSURE

INCREASED CSF PRESSURE DECREASED CSF PRESSURE

TURBIDITY

Clot/Coagulation formation

Xanthochromia

DIFFERENCE IN TRAUMATIC TAP & SAH

Microscopic Exam of CSF

Cause AppearancePolymorphon

uclear Leukocytes

Lymphocytes Protein Glucose

Pyogenic bacterial meningitis

Yellowish, turbid

Markedly increased

Slightly increased or Normal

Markedly increased Decreased

Viral meningitis Clear fluidSlightly increased or Normal

Markedly increased

Slightly increased or Normal

Normal

Tuberculous meningitis

Yellowish and viscous

Slightly increased or Normal

Markedly increased Increased Decreased

Fungal meningits

Yellowish and viscous

Slightly increased or Normal

Markedly increased

Slightly increased or Normal

Normal or decreased

Name the products formed from tyrosine,with the help of a diagram

Name the products formed from tryptophan

• Alanine• Acetoacetyl co A• Formyl group• Niacin and NAD• Serotonin• Melatonin• Hydroxy indole acetic acid• Indican

Classify neurotransmitters

What are endorphins

Synthesis of acetyl choline