1106 Incidence of stroke by their types in population of Ulaanbaatar Mongolia, by age-sex group
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$382 Thursday, November 10, 2005 Poster Abstracts 1103 Clinical diversity of Antiphospholipid protein antibodies in ISellelnic Stroke Kitagawa, y1, Matsuda, H ~, Ishikawa, T ~, Ohtomo, T ~, Yuasa, N ~, Ohkuma, H 2, Sekiyama, S3, Takagi, S3. 2Department of Neurology, Tokai University Haehiofi Hospital, Japan; 2Department of Neurology, Tokai University Tokyo Hospital, Japan; 3Departtnent of Neurology, Tokai University School of Medicine, Japan Pro'pose: Antiphospholipid antibodies (APLs) comprise a heteroge- neous group of autoantibodies, including [3z-glycoprotein I dependent anticardiolipin antibody ([3~-GPI aCL), lupus anticoagulant (LA), and other antiphospholid-proteni antibodies. The purpose of the present study was to clarify the intercorrelations among APLs and to elucidate the pathogenetic role of each antibody in ischemic stroke. Methods: The subjects comprised 250 patients (155 male, 95 females) with ischemic stroke, aged 26 to 92 years (mean 72 years). Five patients with systemic, lupus erythematosus (SLE) (mean 32 years) were included in the present study. We measured [3.2-GPI aCL, IgG aCL, LA, phosphatidylsernie-dependent antiprothrombin antibody (PS-PT), atttiphosphatidylserine antibody (PS), and atttiphosphatidylinositol antibody (PI) in each patient. Results: The incidences of [32-GPI aCE IgG aCL, LA, PS-PT, PS, and PI were 2.8°,5, 12%, 9.2°,5, 7.2%, 9.6°,5, and 8.8°,5, respectively. Among 23 patients with LA, 18 (78°'o) patients had PS-PT. Thus, PS-PT is closely related to LA. PS and/or PI was detectedin 4 (30.8%) of 13 patients under the age of 50 years. Antinuclear antibody was detected in 80% of the patients with aPS attd/or aPI. The carotid ultrasonographic findings indicated that increased IMT, plaque score and carotid stenosis were more common in aPI- and aPS-positive patients than in negative ones. All SLE patients had three or more antiphospholipid protein antibodies. Conclusions: Multiple atttiphospholipid-protein antibodies were found in SLE patients with stroke. LA is closely related to ant-PS- PT, and aPI and aPS are associated with anti-nuclear antibody and precipitation of atherosclerosis. 1104 Ischemie Stroke and Basedow Graves Disease (I case reporO Asbai. K 1, Louhab. N 1, Jafoui. M 1, Kissani. N 1. 2Neurology Department, CHU ~fohamrned gI 3farrakech, ~forocco Background: Basedow -Graves disease is found in 2% to 20% of stroke. Authors report one case of patient with ischemic stroke and Basedow - Graves disease. Case report: A 27 year-old-man, presented with acute left limb monoparesis and partial vertiginous seizures than clonic movement of left limb. Clinical examination showed a lffgh cardiac rate, bilateral exophtalmos and a diffuse goiter. Cerebral CT scan showed a left sylvian cerebral infarcts. Echocardiography showed left ventricular hypertrophy without trombosis. Electrocardiography found cardiac arytlmffa with auricular fibrillation. The antithyrioglobulin antibodies were positive and thyroidian check-up confirmed hyperthyroidism. Conclusion: The concurrence of ischemic stroke and Basedow disease suggests a possible relationship between Basedow -Graves and ische- mic stroke, possibly through a common autoimmune mechanism or by cardiac embolism. 1105 Intensive care repercussion in patients' survival sultering li'om a Cerebrovascular Diseases Asencio, A l, Rodrfguez, y2, Torriente, M a. 1"'Julia Trigo" General Hospital, Havana, Cuba; 2,,julia Trigo" Medical School, Havana, Cuba Cerebrovascular diseases keep on being one of the first cause of death for the time being. The lack of an specific pharmacological treatment brought about a nihilistic attitude, however, it's a fact that the early prevention of this complications improve the clinical development mainly when the patients are treated in specialized stroke units. A descriptive and transversal study were carried out during the first five months of the years 2003 and 2004 on all the patients suffering fi'om cerebrovascular deseases in Martires de Mayari Hospital, some of them discharged fi'om the stroke unit. Our aim was to determine the impact of our Stroke unit in this kind of patients. The average of dead people by cerebrovascular diseases dropped from 35.5% to 15.6?,'0 in the second group as well as the ones who died under a bronchopneunlonia diagnosis. 1106 Incidence of Stroke by their types in population of Ulaanbaatar Mongolia, by age-sex group Damdlaa Baasanjav l, Shuren Dasllzeveg 1 . 1National ~fedieal Research Institute, Ulaanbaatar, 3fongolia Background: The purpose of tiffs study was to estimate the annual incidence rates on stroke - hemorrhagic., ischaemic, subarachnoid, also for all types, in age-sex groups, in population of Ulaanbaatar, Mongolia. Method: First - ever were included in a population based stroke registry in main 6 district of Ulaanbaatar during 1998 1999 y. Annual incidence rates for 1000 pop 16y.o+, were established in tiffs: 16 34 y, 35-39 y, 40-~4 y, 45-'~9y, 50-54y, 55-59y, 60-74y, 75-79y, 80y.o+, and for all age. In two years were registered 2455 eases/m - 1239, f- 1216/. Results: Annual incidence rates of stroke for 1000 pop 16y.o+ respectively by types: Hemorrhagic: - for men: 0.08; 0.53; 0.9; 2.12; 3.8; 3.97; 9.34; 7.87; 9.46; - for women:0.01; 0.37; 1.05; 2.01; 2.99; 3.47; 8.77; 8.; 13.11; Ischaemic: 0.03; 0.15; 0.96; 1.91; 2.17; 3.93; 9.03; 7.32; 11.82; 0.07; 0.26; 1.02; 1.66; 2.27; 1.86; 6.97; 5.56; 13.65; Subarachnoid: - 0.05; 0.15; 0.47; 0.64; 0.68; 0.64; 1.05; 0.75; 1.97; - 0.01; 0.09; 0.33; 0.46; 0.67; 0.22; 1.16; 1.80; 1.12; All types of stroke 0.17; 0.91; 2.39; 4.9; 7.09; 8.95; 20.78; 26; 26; 0.1; 0.89; 2.49; 4.4; 6.31; 5.48; 17.73; 16.02; 28.44; 38.9"/o ischaenffc, 46.9°,5 hemorrhagic, 8.3"/o subarachnoid. Conclusion: The incidence rates of hemorrhagic type is conspicuously higher than other countries, than that of Akita, Japan, 1964-1969, that considered with the lffghest incidence rate in the world. Ratia hemor- rhagic and ischaenffc is 1.4 : 1.0 with predominance of hemorrhagic over ischaenffc. 1107 Delayed onset head tremor caused by Thalamic Infarction Bae, j1, Lee, S 1. 2Department o/neurology, Dong-Eui Hospital, Busan, Korea Background: Thalamic infarction may produce some kinds of invol- untary movement, such as chorea, dystonia, athetosis, or tremor. Tremor associated with thalarnic infarction has rarely been reported. Especially, isolated head tremor without appendicular tremor or other cerebellar sign is even more infrequent. Case: A 59-year-old woman developed head tremor 3 months after the episode of left thalamic infarction. Initially, She had only numbness and paresthesia in the right face and extremities, and conditions were slowly improved. The head tremor was side to side features, as No/No type head tremor. It's activity increased with emotional exdtement and stopped at sleep. The tremor was markdly improved by adnffnistration of L-dopa. And 6 months later, head tremor was nearly completely disappeared.
Transcript of 1106 Incidence of stroke by their types in population of Ulaanbaatar Mongolia, by age-sex group
$382 Thursday, November 10, 2005 Poster Abstracts
1103 Clinical diversity of Antiphospholipid protein antibodies in IS ellelnic Stroke
Kitagawa, y1, Matsuda, H ~, Ishikawa, T ~, Ohtomo, T ~, Yuasa, N ~, Ohkuma, H 2, Sekiyama, S 3, Takagi, S 3. 2Department of Neurology, Tokai University Haehiofi Hospital, Japan; 2Department of Neurology, Tokai University Tokyo Hospital, Japan; 3Departtnent of Neurology, Tokai University School of Medicine, Japan
Pro'pose: Antiphospholipid antibodies (APLs) comprise a heteroge- neous group of autoantibodies, including [3z-glycoprotein I dependent anticardiolipin antibody ([3~-GPI aCL), lupus anticoagulant (LA), and other antiphospholid-proteni antibodies. The purpose of the present study was to clarify the intercorrelations among APLs and to elucidate the pathogenetic role of each antibody in ischemic stroke. Methods: The subjects comprised 250 patients (155 male, 95 females) with ischemic stroke, aged 26 to 92 years (mean 72 years). Five patients with systemic, lupus erythematosus (SLE) (mean 32 years) were included in the present study. We measured [3.2-GPI aCL, IgG aCL, LA, phosphatidylsernie-dependent antiprothrombin antibody (PS-PT), atttiphosphatidylserine antibody (PS), and atttiphosphatidylinositol antibody (PI) in each patient. Results: The incidences of [32-GPI a C E IgG aCL, LA, PS-PT, PS, and PI were 2.8°,5, 12%, 9.2°,5, 7.2%, 9.6°,5, and 8.8°,5, respectively. Among 23 patients with LA, 18 (78°'o) patients had PS-PT. Thus, PS-PT is closely related to LA. PS and/or PI was detectedin 4 (30.8%) of 13 patients under the age of 50 years. Antinuclear antibody was detected in 80% of the patients with aPS attd/or aPI. The carotid ultrasonographic findings indicated that increased IMT, plaque score and carotid stenosis were more common in aPI- and aPS-positive patients than in negative ones. All SLE patients had three or more antiphospholipid protein antibodies. Conclusions: Multiple atttiphospholipid-protein antibodies were found in SLE patients with stroke. LA is closely related to ant-PS- PT, and aPI and aPS are associated with anti-nuclear antibody and precipitation of atherosclerosis.
1104 Ischemie Stroke and Basedow Graves Disease (I case reporO
Asbai. K 1, Louhab. N 1, Jafoui. M 1, Kissani. N 1. 2Neurology Department, CHU ~fohamrned gI 3farrakech, ~forocco
Background: Basedow -Graves disease is found in 2% to 20% of stroke. Authors report one case of patient with ischemic stroke and Basedow - Graves disease. Case report: A 27 year-old-man, presented with acute left limb monoparesis and partial vertiginous seizures than clonic movement of left limb. Clinical examination showed a lffgh cardiac rate, bilateral exophtalmos and a diffuse goiter. Cerebral CT scan showed a left sylvian cerebral infarcts. Echocardiography showed left ventricular hypertrophy without trombosis. Electrocardiography found cardiac arytlmffa with auricular fibrillation. The antithyrioglobulin antibodies were positive and thyroidian check-up confirmed hyperthyroidism. Conclusion: The concurrence of ischemic stroke and Basedow disease suggests a possible relationship between Basedow -Graves and ische- mic stroke, possibly through a common autoimmune mechanism or by cardiac embolism.
1105 Intensive care repercussion in patients' survival sultering li'om a Cerebrovascular Diseases
Asencio, A l, Rodrfguez, y2, Torriente, M a. 1"'Julia Trigo" General Hospital, Havana, Cuba; 2,,julia Trigo" Medical School, Havana, Cuba
Cerebrovascular diseases keep on being one of the first cause of death for the time being. The lack of an specific pharmacological treatment brought about a nihilistic attitude, however, it's a fact that the early
prevention of this complications improve the clinical development mainly when the patients are treated in specialized stroke units.
A descriptive and transversal study were carried out during the first five months of the years 2003 and 2004 on all the patients suffering fi'om cerebrovascular deseases in Martires de Mayari Hospital, some of them discharged fi'om the stroke unit. Our aim was to determine the impact of our Stroke unit in this kind of patients.
The average of dead people by cerebrovascular diseases dropped from 35.5% to 15.6?,'0 in the second group as well as the ones who died under a bronchopneunlonia diagnosis.
1106 Incidence of Stroke by their types in population of Ulaanbaatar Mongolia, by age-sex group
Damdlaa Baasanjav l, Shuren Dasllzeveg 1 . 1National ~fedieal Research Institute, Ulaanbaatar, 3fongolia
Background: The purpose of tiffs study was to estimate the annual incidence rates on stroke - hemorrhagic., ischaemic, subarachnoid, also for all types, in age-sex groups, in population of Ulaanbaatar, Mongolia. Method: First - ever were included in a population based stroke registry in main 6 district of Ulaanbaatar during 1998 1999 y. Annual incidence rates for 1000 pop 16y.o+, were established in tiffs: 16 34 y, 35-39 y, 40-~4 y, 45-'~9y, 50-54y, 55-59y, 60-74y, 75-79y, 80y.o+, and for all age. In two years were registered 2455 eases /m - 1239, f - 1216/. Results: Annual incidence rates of stroke for 1000 pop 16y.o+ respectively by types:
Hemorrhagic: - for men: 0.08; 0.53; 0.9; 2.12; 3.8; 3.97; 9.34; 7.87; 9.46; - for women:0.01; 0.37; 1.05; 2.01; 2.99; 3.47; 8.77; 8.; 13.11;
Ischaemic: 0.03; 0.15; 0.96; 1.91; 2.17; 3.93; 9.03; 7.32; 11.82; 0.07; 0.26; 1.02; 1.66; 2.27; 1.86; 6.97; 5.56; 13.65;
Subarachnoid: - 0.05; 0.15; 0.47; 0.64; 0.68; 0.64; 1.05; 0.75; 1.97; - 0.01; 0.09; 0.33; 0.46; 0.67; 0.22; 1.16; 1.80; 1.12;
All types of stroke 0.17; 0.91; 2.39; 4.9; 7.09; 8.95; 20.78; 26; 26; 0.1; 0.89; 2.49; 4.4; 6.31; 5.48; 17.73; 16.02; 28.44; 38.9"/o ischaenffc, 46.9°,5 hemorrhagic, 8.3"/o subarachnoid.
Conclusion: The incidence rates of hemorrhagic type is conspicuously higher than other countries, than that of Akita, Japan, 1964-1969, that considered with the lffghest incidence rate in the world. Ratia hemor- rhagic and ischaenffc is 1.4 : 1.0 with predominance of hemorrhagic over ischaenffc.
1107 Delayed onset head tremor caused by Thalamic Infarction
Bae, j1, Lee, S 1. 2Department o/neurology, Dong-Eui Hospital, Busan, Korea
Background: Thalamic infarction may produce some kinds of invol- untary movement, such as chorea, dystonia, athetosis, or tremor. Tremor associated with thalarnic infarction has rarely been reported. Especially, isolated head tremor without appendicular tremor or other cerebellar sign is even more infrequent. Case: A 59-year-old woman developed head tremor 3 months after the episode of left thalamic infarction. Initially, She had only numbness and paresthesia in the right face and extremities, and conditions were slowly improved. The head tremor was side to side features, as No/No type head tremor. It 's activity increased with emotional exdtement and stopped at sleep. The tremor was markdly improved by adnffnistration of L-dopa. And 6 months later, head tremor was nearly completely disappeared.
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