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Transcript of 1 Tim Hunter University of Vermont Core Manager, VGN Microarray Facility Core Manager, VCC DNA...
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Tim HunterUniversity of VermontCore Manager, VGN Microarray FacilityCore Manager, VCC DNA Analysis FacilityAsst Director, Translational Technologies Unit, CCTS
NNetwork of etwork of IIDeA-funded DeA-funded CCore ore LLaboratories (NICL): aboratories (NICL): Turning NICL into Gold Turning NICL into Gold
IDeA Central Regional MeetingMay 23-25, 2011Hilton Hotel, Omaha, Nebraska
NCRR Strategic Plan: 2009- 2013
Build capacity
Advance research through animal models
Foster research through technologies
Develop informatics approaches to support research
Strengthen the research workforce
Maximize partnerships
Dr. Barbara Alving, NISBRE 2008
The Cores Need a Voice:The Cores Need a Voice:
At the level of the NCRR activities:
Lack of core representation during COBRE/INBRE/RCMI regional meetings
NISBRE conference attended by PI’s, office staff (admin), but as a rule few core staff are given the opportunity to participate due to lack of funding
Information sent to the grant award PIs rarely trickles down to the cores
The cores need a voice: A Network was Born
(NICL)Presence at regional/national meetings/NIH
Help forge and develop partnerships between NICL and other regional and national core organizations
Discussion on partnership with the Association of Biomolecular Resource Facility (ABRF.org)
Tap into existing research groups, and presence in scientific community (FASEB membership)
NICL annual national meeting (representation during NISBRE)
Advocacy: Steering Committee was formed
2008 “impromptu” core breakout session organized by Sol- Church and Hunter. served as catalyst for the building of the new core network
NICL Steering Committee:• Tim Hunter
– Vermont Genetics Network at UVM • Katia Sol-Church
– Nemours, DE• Stephen Bobin
– Dartmouth Medical School, NH• Steve Jennings
– University of Arkansas at Little Rock• James Foster
– University of Idaho• Faye Schilkey
– National Center for Genome Resources, NM
• Kate McInnerney– Montana State University
• ???????
Northeast
South
Central
West
New Steering Committee Member: Central Region
Cynthia AndersonProgram Coordinator, SD Biomedical Research Infrastructure NetworkAssociate Director, Western South Dakota DNA Core Facility Assistant Professor, BiologyBlack Hills State [email protected]
NICL Mission Statement:
The mission of this network is to support, encourage, and facilitate resource sharing and collaboration among NCRR-funded cores and shared-resource facilities.
NICL Objectives:NICL Objectives: To establish a national network of cores that share expertise and provide
mutual support to build capacity and deliver quality services to NCRR-funded investigators
To establish and maintain a web site (NICLweb.org) to support effective communication between the network members and provide a bridge to the National Association of IDeA Principal Investigators
To promote the development of state-of-the-art research methodologies and the flow of technical expertise within the NCRR-funded programs (COBRE, INBRE, RCMI, CTSA)
To share knowledge and expertise on long-range planning and core operations and to provide educational and career growth opportunities to its members
To help forge and develop partnerships between NICL and other regional and national core organizations
NICL: The EvolutionNICL: The Evolution
2008 “impromptu” core breakout session organized by Sol- Church and Hunter. This served as catalyst for the building of the new core network Explore how best to insure Core viability
post-COBRE/INBRE funding Discuss ways to help promote interactions
between NIH-funded cores/resource facilities. Maximize Partnerships
10
What We Learned: Common Issues Some NCRR-funded cores are isolated:
No easy access to medical schools (ID) Sometimes difficult to hire specialized staff Some cores want to do outreach but don’t know how Information does not get to them, need a central place
Very few attendees are aware of federal regulations regarding core fees structure – where is the information?
Most had never developed chargebacks or a business plan to sustain critical core activities beyond NCRR funding.
No formal standards on how core charge back should be implemented.
Need for a workshop on core management? Most were not aware of the opportunities for networking in the
“Core Community”
NICL : Providing a Voice for the Cores Provide Forums for Core Networking
Leverage through ABRF and NISBRE
Establish Tools to promote information exchange and Identify Resources NICL Website (www.niclweb.org)
Promote collaboration, education & resource sharing Establish “Fee Waivers” or “special pricing” to encourage Network
interactions lower prices (subsidized). “In-kind” services between core facilities
Road block might be institutional: not set-up for easy sharing (e.g. purchasing dept. have difficulties dealing with PO’s for outside customers).
Memo of Understanding (MOU): a standard document used for resource sharing by all cores in the NCRR Network
NICL: The EvolutionNICL: The Evolution 2009: NICL Satellite Meeting at ABRF
35 NICL members 18 INBRE-funded 10 COBRE-funded 7 RCMI-funded 15 states: AR, DE, GA, ID, ME, MS, MT, ND ,NH, NM, RI, SC, TN,
VT, WV 20 different institutions
9 GUESTS from NIH/NCRR (DC) ABRF 2009 Organizing Comm. (CT) ABRF Executive Board (PA) ABRF Membership Comm. (CA) NIH/NCBI (DC) FASEB (NC) BioServe (MD)
RFI Released by NIH-NCRR: Improving Core Facilities
NIH/NCRR Meetings on Efficient Core Management
The Efficient Management and Utilization of Core Facilities
July 14 – 15, 2009
managing core facilities issues of cost efficiency,
management and access
finding and accessing core
facilities government policies
governing managing and reporting
training core directors
quality improvement
Moving Forward in the Efficient Management and Use of Core Facilities
November 15 – 16, 2010 updates on maximizing the use
and efficiency of existing NIH-funded research core facilities
developing effective training programs for core facility directors
exploring software options for enhancing administrative management of core facilities
creating a national registry of core resources
standardizing compliance with OMB Circular A21
NISBRE 2010 Core Personnel Travel Awardees:
•Jennifer Holbrook: Nemours/A.I.duPont Hospital for Children
•Bryon Grove: University of North Dakota
•Cheryl J Aine: University of New Mexico
•James Eudy: University of Nebraska Medical Center
•Kate McInnerney: Montana State University
•Kristen-Ashley Muirhead: Dartmouth Medical School.
•Manjula Sunkara: University of Kentucky
•Mikhail Golovko: University of North Dakota (COBRE)
•Vivek Nerurka: University of Hawaii
•Bonnibel Delagado: University of Puerto Rico Medical Sciences
NICL Evolution: A First!!
NICL Evolution: NISBRE 201012:45 -3:30PM: NICL Organizational Meeting (James Foster, U Idaho)
•12:30-1:30PM: NICL Workshop Session I: Educational Outreach Through Core Facilities (Janet Murray, Vermont Genetics Network, and Scott Seville, Wyoming)
-How to develop a culture of research in your state through outreach activities in collaboration with institutional cores
•1:30-3:30PM: NICL Workshop Session II: Best Practices in Core Management(Steve Bobin, Dartmouth, Faye Shilkey, NCGR, NM, and Nick Ambulos, U Maryland)
-The business of running a core facility
•3:30-5:00PM: NICL Workshop Session III: Shared Resource Networks(SteveJennings, U Arkansas at Little Rock, and Tim Hunter, Vermont Genetics Network)
-Networks that can promote and foster exchange of core resources.
All workshop sessions are interactive and designed to encourage exchange of challenges and successes on the topic being discussed that can be unique
to operating IDeA-funded core laboratories.
NICL Organizational Meeting: Organized and led by James Foster
Break into working groups to discuss and summarize
‣Group 1: What are core facilities’ needs and what barriers do we face? (Steve Bobin)
‣Group 2: What resources and opportunities currently exist for core operations? (Kate McInnerney)
‣Group 3: What needs to be done to formalize the NICL organization? (Steve Jennings)
‣Group 4: How can cores sustain dialog and information sharing? (Tim Hunter)
Afterwards
‣Register your core at: http://vgn.uvm.edu/corefacilities/
‣NICL board presents summary to NCRR (before end of NISBRE)
‣NICL convenes at ABRF 2011
‣Continue discussion online at niclweb.org
Key Recommendations to NCRR:
1. Fund: Support and expand the NICL organization through NICL leadership with external funding.
2. Authorize: Identify NICL as an NCRR supported entity with the mandate of coordinating core facilities in IDEA states.
3. Authorize: NICL be authorized by NCRR to test and certify the usability and effectiveness of prototype databases, ontologies, and similar resources.
4. Fund: Provide matching funds for cooperative projects between NICL members.
5. Clarify: Mediate disputes with local institutions; clarify budgeting and operations requirements and guidelines.
6. Bargain: Mediate collective bargaining with service and commodity providers, for example to acquire group discounts on licenses and service contracts.
7. Train: Provide administrative training to core leadership and to key institutional personnel (such as SRO personnel).
Tools to:
- Promote
Communicati
on
- Education of
Core
Directors
-Identify and
inventory
cores (Foster
Sharing
of
Resources)
www.niclweb.org
Resources Developed to Support Network:
Identifying Resources:
-Hardware
-Expertise
2009 Established database for voluntary population of NICL Core’s
Search Provides:All cores in state
Link to core website
Location
Contact info
Services offered
Description of facility
Affiliated associations
Equipment
Date last updated
VGN Searchable Core Facilities Database:Statistics
322 Cores
44 States + DC
126 Institutes
11 Associations
67 NICL Cores listed
102 Service Keywords 100 Distinct Service Keywords offered by Core
Facilities
Data captured May 11, 2011
NICL Website:How it is being used
Communication through forums Prevent Local duplication of research
infrastructure Finding distributed unique strengths of resources
within a network (NICL, MWACD, NERLSCD, NERTRN)
Outsourcing Identify local resource to offset vacation in single
staffed core Identify expertise: protocols and troubleshooting
The future for NICL: Provide Tools and Forums to promote networking,
collaborations, education, and identification and sharing of resources
Use for leveraging Instrument service contracts? Reagents and consumables? Other?
What are other ways we can use the NICL network to our advantage?
What opportunities exist where networks can help What are ways we can work with NAIPI to
strengthen core communication and education
The future for NICL:
What division does the IDeA program transfer to Here we need to have a voice!
Changes on the horizon…….
ResourceSharing