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Kurdistan Region Government-IraqMinistry of Higher Education & Scientific ResearchSalahaddin University-ErbilCollege of Science – Chemistry department

Course book of Biochemistry

For chemistry students, Fourth stage 2 hours in weak, 2013-2014

Dr. Kamaran Kaiani Abdoulrahman

First courseCarbohydrate metabolismDigestion of carbohydrateGlycolysis pathwayHormonal control glucose metabolism by insulinHormonal control by epinephrine (adrenaline) and glucagonFate of pyruvateCitric acid cycleGlycogen metabolismGluconeogenesisGalactose metabolismFructose metabolismPentose phosphate pathway

Disorders of carbohydrate metabolism:Glycogen storage dieseasesDefects in glycolysisGalactosemiaDisorders in fructose metabolismPentosuria

Diabetes mellitusTypes of Diabetes mellitus

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Lipid metabolismDigestion of lipids in intestineAbsorption of lipids by intestinal mucosal cellsResynthesis of triacylglycerol and cholesteryl esters by intestinal mucosal cellsPlasma lipoproteinsApolipoproteins Biosynthesis of fatty acidsFormation of double bonds in fatty acids Fatty acid breakdown Ketone bodiesBiosynthesis of cholesterol

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Clinical disorders of lipid metabolism:Disorders of VLDL and chylomicrons-hypertriglyceridemia alone.Disorders of LDL-hypercholesterolaemia alone.Disorders of HDL.Combined hyperlipidaemia.Fatty liver accumulation due to Alcohol consumptionTherapies available to treat hyperlipidaemia

Amino acid metabolismDigestion of proteinUrea cycleMetabolism of aromatic amino acidsMetabolism of sulfur containing amino acids

Second course

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References

Biochemistry

Lubert Stryer

The foundation of Biochemistry

Lehninger

Text book of Biochemistry

Thomas M. Devlin

Illustrated Biochemistry

Harpers

Biochemisrty

Lippincotts 5