02-Ovarian & Uterine Cycles

7/25/2019 02-Ovarian & Uterine Cycles

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OVARIAN AND UTERINEOVARIAN AND UTERINE

CYCLESCYCLES

Dr. Saeed VohraDr. Saeed Vohra


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http://education.yahoo.com/reference/gray/illustrations/figure;_ylt=AlTcRxodcCXDgvBg.SbnNNltHokC?id=1166http://education.yahoo.com/reference/gray/illustrations/figure;_ylt=AlTcRxodcCXDgvBg.SbnNNltHokC?id=1166


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Female Reproductive Ccle!Female Reproductive Ccle!

" Start! at pu#ertStart! at pu#ert

" Normall co$ti$ue! throu%hout theNormall co$ti$ue! throu%hout the

reproductive ear!reproductive ear!" &o$thl 'emale !e(ual)reproductive ccle&o$thl 'emale !e(ual)reproductive ccle

i$volve! activitie! o' hpothalamu!*i$volve! activitie! o' hpothalamu!*

pituitar %la$d* ovarie!* uteru!* uteri$epituitar %la$d* ovarie!* uteru!* uteri$etu#e!* va%i$a a$d mammar %la$d!tu#e!* va%i$a a$d mammar %la$d!


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1. The ovarian cycle =(changes in ovary)

2. The uterine cycle =(changes in the mucosa of the uterus)

The two cycles of the female

Female Reproductive Ccle!Female Reproductive Ccle!


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+$R,+$R,

" +o$adotropi$-relea!i$% hormo$e +$R,/+o$adotropi$-relea!i$% hormo$e +$R,/i! !$th!i0ed # $euro!ecretor cell! i$i! !$th!i0ed # $euro!ecretor cell! i$

the hpothalamu!the hpothalamu!

" Carried to the a$terior pituitar %la$d #Carried to the a$terior pituitar %la$d #

hpoph!ial portal !!temhpoph!ial portal !!tem

" Stimulate! the relea!e o' 1 hormo$e!Stimulate! the relea!e o' 1 hormo$e!

produced # thi! %la$d that act o$ ovarie!produced # thi! %la$d that act o$ ovarie!


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FS,FS,

" Follicle-Stimulati$% ,ormo$e !timulate!Follicle-Stimulati$% ,ormo$e !timulate!

the developme$t o' ovaria$ 'ollicle!the developme$t o' ovaria$ 'ollicle!

" 2roductio$ o' E!tro%e$ # the 'ollicular2roductio$ o' E!tro%e$ # the 'ollicular

cell!cell!


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L,L,

" Lutei$i0i$% ,ormo$e !erve! a! the tri%%erLutei$i0i$% ,ormo$e !erve! a! the tri%%er

'or ovulatio$'or ovulatio$

" Stimulate! the 'ollicular cell! a$d corpu!Stimulate! the 'ollicular cell! a$d corpu!

luteum to produce pro%e!tero$eluteum to produce pro%e!tero$e


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OVARIAN CYCLEOVARIAN CYCLE

" FS, a$d L, produce cclic cha$%e! i$ ovarie!.FS, a$d L, produce cclic cha$%e! i$ ovarie!.

" The cau!eThe cau!e

3.3. Developme$t o' 'ollicle!Developme$t o' 'ollicle!

1.1. Ovulatio$Ovulatio$

4.4. Formatio$ o' corpu! luteumFormatio$ o' corpu! luteum

5e%i$$i$% at pu#ert 33-36 ear!/ 7 e$di$% at the 8me$opau!e9 6:-6; r!/*

the rhthmic cclic cha$%e!


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Follicular DevelopmentFollicular Development

The development of the ovarianThe development of the ovarian

follicle is characterized byfollicle is characterized by11 !rowth and differentiation of primary!rowth and differentiation of primary

oocyteoocyte"" #roliferation of follicular cells#roliferation of follicular cells

$$ Formation of %ona #ellucidaFormation of %ona #ellucida

&& Development of the Theca FolliculiDevelopment of the Theca Folliculi


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Theca FolliculiTheca Folliculi

" Formed a! the primar 'ollicle i$crea!e! i$Formed a! the primar 'ollicle i$crea!e! i$

!i0e a$d the ad=ace$t co$$ective ti!!ue!i0e a$d the ad=ace$t co$$ective ti!!ue

or%a$i0e! i$to a cap!uleor%a$i0e! i$to a cap!ule

" Theca I$ter$a> I$ter$al* va!cular a$dTheca I$ter$a> I$ter$al* va!cular a$d

%la$dular%la$dular

" Theca E(ter$a> A cap!ule li?e laerTheca E(ter$a> A cap!ule li?e laer


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A$trumA$trum

" I! a lar%e 'luid 'illed cavitI! a lar%e 'luid 'illed cavitappear! arou$d the 'ollicularappear! arou$d the 'ollicular

cell! o' ovaria$ 'olliclecell! o' ovaria$ 'ollicle

" Co$tai$! 'ollicular 'luidCo$tai$! 'ollicular 'luid

" Ovaria$ 'ollicle $o< called aOvaria$ 'ollicle $o< called a

ve!icular orve!icular or !eco$dar 'ollicle!eco$dar 'ollicle


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Cumulu! Oophoru!Cumulu! Oophoru!

" The primar oocteThe primar ooctei! pu!hed a!ide o'i! pu!hed a!ide o'the 'ollicle calledthe 'ollicle called

Cumulu! Oophoru!Cumulu! Oophoru!" ,ere it i!,ere it i!

!urrou$ded # a!urrou$ded # amou$dmou$d// ma!!ma!! o'o'

'ollicular cell!'ollicular cell!" It pro=ect! i$to theIt pro=ect! i$to the

a$truma$trum


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" The 'ollicle #ecome! e$lar%e u$til it %et!The 'ollicle #ecome! e$lar%e u$til it %et!

maturitmaturit

" 2roduce! !


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E!tro%e$E!tro%e$

" +ro


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Ovulatio$Ovulatio$" It occur! arou$d mid ccle a#out 36 da! i$ a 1It occur! arou$d mid ccle a#out 36 da! i$ a 1

da me$!trual ccleda me$!trual ccle

" Ovaria$ 'ollicle u$der%oe! !udde$ %ro


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Ovulatio$Ovulatio$" Cumulu! Oophoru! detach 'rom i$terior o' theCumulu! Oophoru! detach 'rom i$terior o' the

di!te$ded 'ollicledi!te$ded 'ollicle

" It i! tri%%ered # a !ur%e o' L, productio$It i! tri%%ered # a !ur%e o' L, productio$

" It u!uall 'ollo


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Ovulatio$Ovulatio$

" E(pul!io$ o' oocte re!ult! 'rom rai!edE(pul!io$ o' oocte re!ult! 'rom rai!edi$tra'ollicular pre!!urei$tra'ollicular pre!!ure

" The e(pelled !eco$dar oocte i!The e(pelled !eco$dar oocte i!!urrou$ded # Bo$a 2ellucida a$d laer!!urrou$ded # Bo$a 2ellucida a$d laer!

o' 'ollicular cell! called Coro$a Radiatao' 'ollicular cell! called Coro$a Radiata

" Bo$a 2ellucida i! compo!ed o' 4Bo$a 2ellucida i! compo!ed o' 4

%lcoprotei$! B2A* B25 7 B2C%lcoprotei$! B2A* B25 7 B2C


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Corpu! LuteumCorpu! Luteum

" A'ter ovulatio$ the


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Corpu! LuteumCorpu! Luteum" It !ecrete! 2ro%e!tero$e a$d little e!tro%e$It !ecrete! 2ro%e!tero$e a$d little e!tro%e$

" The!e hormo$e! prepare e$dometrium 'orThe!e hormo$e! prepare e$dometrium 'or

impla$tatio$ o' Fertili0ed Ovum 5la!toc!t/impla$tatio$ o' Fertili0ed Ovum 5la!toc!t/

" I' the oocte i! 'ertili0ed the CL e$lar%e! 7I' the oocte i! 'ertili0ed the CL e$lar%e! 7

remai$! active 'or 'ir!t 1:


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Uteri$e or &e$!trual CcleUteri$e or &e$!trual Ccle

" It i! the period duri$%


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&e$!trual Ccle&e$!trual Ccle

" Avera%e me$!trual ccle i! 1 da!Avera%e me$!trual ccle i! 1 da!

" Da 3 i! the da


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2ha!e! o' &e$!trual Ccle2ha!e! o' &e$!trual Ccle

" &e$!trual 2ha!e&e$!trual 2ha!e

"2roli'erative 2ha!e2roli'erative 2ha!e

" Luteal 2ha!eLuteal 2ha!e

" I!chemic 2ha!eI!chemic 2ha!e


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&e$!trual 2ha!e&e$!trual 2ha!e

" Start!


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2roli'erative 2ha!e2roli'erative 2ha!e

" I! a pha!e o' repair a$d proli'eratio$I! a pha!e o' repair a$d proli'eratio$

" La!t! 'or da!La!t! 'or da!

" Coi$cide!


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Luteal 2ha!eLuteal 2ha!e

" I! a !ecretor or pro%e!tero$e pha!eI! a !ecretor or pro%e!tero$e pha!e

" La!ti$% a#out 34 da!La!ti$% a#out 34 da!

" Coi$cide!


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Luteal 2ha!eLuteal 2ha!e

" Spiral arterie! %ro< i$to the !uper'icialSpiral arterie! %ro< i$to the !uper'iciallaerlaer

" Arterie! #ecome i$crea!i$%l coiledArterie! #ecome i$crea!i$%l coiled

" Lar%e ve$ou! $et


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I' Fertili0atio$ Occur!I' Fertili0atio$ Occur!

" Fertili0ed ovum impla$t! i$ e$dometriumFertili0ed ovum impla$t! i$ e$dometriumo$ a#out o$ a#out ththda o' thi! pha!eda o' thi! pha!e

" ,C+ hormo$e !ecreted #,C+ hormo$e !ecreted #!$ctiotropho#la!t ?eep! the corpu!!$ctiotropho#la!t ?eep! the corpu!luteum !ecreti$% e!tro%e$ a$dluteum !ecreti$% e!tro%e$ a$d

pro%e!tero$epro%e!tero$e

" The luteal pha!e co$ti$ue! a$dThe luteal pha!e co$ti$ue! a$dme$!truatio$ doe! $ot occurme$!truatio$ doe! $ot occur


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I' Fertili0atio$ Doe!$t OccurI' Fertili0atio$ Doe!$t Occur

" No ,C+No ,C+

" Corpu! luteum de%e$erate!Corpu! luteum de%e$erate!

" E!tro%e$ a$d pro%e!tero$e level! 'allE!tro%e$ a$d pro%e!tero$e level! 'all

" Secretor e$dometrium e$ter! a$ i!chemicSecretor e$dometrium e$ter! a$ i!chemicpha!epha!e

" &e$!truatio$ occur!&e$!truatio$ occur!


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I!chemic 2ha!eI!chemic 2ha!e

" Decrea!ed level! o' e!tro%e$ 7 pro%e!tero$eDecrea!ed level! o' e!tro%e$ 7 pro%e!tero$e

" Stoppa%e o' %la$dular !ecretio$Stoppa%e o' %la$dular !ecretio$

" Lo!! o' i$ter!titial 'luidLo!! o' i$ter!titial 'luid

" &ar?ed !hri$?i$% o' e$dometrium&ar?ed !hri$?i$% o' e$dometrium

" Spiral arterie! #ecome co$!trictedSpiral arterie! #ecome co$!tricted

" Ve$ou! !ta!i! 7 I!chemic $ecro!i!Ve$ou! !ta!i! 7 I!chemic $ecro!i!

" Rupture o' dama%ed ve!!el


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I!chemic 2ha!eI!chemic 2ha!e

" 2ool! o' #lood 'orm a$d #rea? throu%h the2ool! o' #lood 'orm a$d #rea? throu%h thee$dometrial !ur'acee$dometrial !ur'ace

" Re!ulti$% i$ #leedi$% i$ uteri$e lume$ a$dRe!ulti$% i$ #leedi$% i$ uteri$e lume$ a$d'rom the va%i$a'rom the va%i$a

" Lo!! o' 1:-: ml o' #loodLo!! o' 1:-: ml o' #lood

" E$tire compact laer a$d mo!t o' theE$tire compact laer a$d mo!t o' the

!po$% laer o' e$dometrium i! di!carded!po$% laer o' e$dometrium i! di!carded


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2re%$a$c 2ha!e2re%$a$c 2ha!e

" I' pre%$a$c occur!* e$dometrium pa!!e!I' pre%$a$c occur!* e$dometrium pa!!e!i$to the pre%$a$c pha!ei$to the pre%$a$c pha!e

"

&e$!truatio$ ccle re!ume! -3:


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A$ovulatio$A$ovulatio$

" Some

02-Ovarian & Uterine Cycles

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