Chapter – 6      

 LITERATURE CITED 

Literature Cited

174

1. Abe, K., S. Yoshida, B.D. Watson, R. Busto, K. Kogure and M.D.

Ginoberg. 1983. alpha-Tocopherol and ubiquinones in rat brain subjected to

decapitation ischemia. Brain Res. 273, 166.

2. Aberg, F., E.L. Appelkvist, G. Dallner and L. Ernster. 1992. Distribution

and redox state of ubiquinones in rat and human tissues. Archives of

biochemistry and biophysics. 295 (2): 230–234.

3. Alleva, R., M. Tomasetti, S. Bompadre and G.P. Littarru. 1997. Oxidation

of LDL and their subfractions: kinetic aspects and CoQ10 content. Molecular

Aspects of Medicine. 18 (Suppl): S105-12.

4. Anonymous. 1976a. Tobacco waste for agricultural industry,

Pesticides.10 (5): 51-52.

5. Aoyagi, S. and K. Sakurai. 1979. Jpn. Kokai Tokkya Koho. JP 79,46,733.

6. Asahina, M., H. Kato and H. Fukawa. 1970. Solanesol from potato leaves.

Ger. Pat. 2019835. Chem.Abst. 74: 28733t (1971).

7. Barshop, B.A. and J.A. Gangoiti. 2007. Analysis of coenzyme Q in human

blood and tissues. Mitochondrion 7S: S89.

8. Beal, M.F. 2002. Coenzyme Q10 as a possible treatment for

neurodegenerative diseases. Free Radic. Res. 36(4): 455-460.

9. Beal, M.F. and C.W. Shults. 2003. Effects of Coenzyme Q10 in Huntington's

disease and Early Parkinson's disease. Biofactors. 18: 153.

10. Beal, M.F. 2004. Mitochondrial dysfunction and oxidative damage in

Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential

treatment. J Bioenerg. Biomembr. 36: 381.

11. Berbel-Garcia, A., H.R. Barbera-Farre and J.P. Etessam. 2004. Coenzyme

Q10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient

with MELAS. Clin Neuropharmacol. 27: 187-191.

12. Bhagavan, H.N. and R.K. Chopra. 2005. Potential role of ubiquinone

(coenzyme Q10) in pediatric cardiomyopathy. Clin. Nutr. 24: 331-338.

13. Bhagavan, H. N. and R.K. Chopra. 2006. Coenzyme Q10: Absorption,

tissue uptake, metabolism and pharmacokinetics. Free Radical Research.

40 (5): 445–453.

Literature Cited

175

14. Bhagavan, H.N. and R.K. Chopra. 2007. Plasma coenzyme Q10 response to

oral ingestion of coenzyme Q10 formulations. Mitochondrion 7 (Suppl):

S78–88.

15. Billinsky, W.R. and R.L. Stedman. 1962. Analytical studies on solanesol

like substances in tobacco. J.A.O.A.C. 45: 532-535.

16. Bliznakov, E.G. and G.L. Hunt. 1986. The Miracle Nutrient: Coenzyme

Q10. Bantam Books, New York.

17. Buettner, C., R.S. Phillips, R.B. Davis, P. Gardiner and M.A. Mittleman.

2007. Use of dietary supplements among United States adults with coronary

artery disease and atherosclerotic risks. Am.J. Cardiol. 99: 661-666.

18. Bunaciu, A.A., H.Y. Aboul-Enein and S. Fleschin. 2007. FT-IR

spectrophotometric analysis of coenzyme Q10 (CoQ10) and its

pharmaceutical formulations. Prep. Biochem. Biotechnol. 37: 59-65.

19. Cao, X.L., Y.T. Xu, G.M. Zhang, S.M. Xie, Y.M. Dong and Y. Ito. 2006.

Purification of coenzyme Q10 from fermentation extract: High-speed

counter-current chromatography versus silica gel column chromatography.

J. Chromatogr. A. 1127: 92.

20. Carruthers, W. and R.A.W. Johnstone. 1960. Alcohols of tobacco -

Solanesol and n-docosonal. Chem. and Ind. 867-868.

21. Chamberlain, W.J., R.F. Severson and T. Chortyk. 1990. Determination of

solanesol in tobacco by capillary gas chromatography. J. Chromatogr.

513: 55-60.

22. Chaplin, J.F. and G.S. Miner. 1980. Chemical composition of tobacco and

tobacco smoke. Rec. Adv. Tob. Sci. 6:3.

23. Charlton, A. 2004. Medicinal uses of tobacco in history. J. R. Soc. Med. 97:

292.

24. Chen, J., X. Liu, X. Xu, F.S. Lee and X. Wang. 2007. Rapid determination

of total solanesol in tobacco leaf by ultrasound-assisted extraction with RP-

HPLC and ESI-TOF/MS. J. Pharm. Biomed. Anal. 43: 879-885.

25. Chen, J., J. Liu, F.S. Lee and X. Wang. 2008. Optimization of HPLC-APCI-

MS conditions for the qualitative and quantitative determination of total

solanesol in tobacco leaves. J. Sep. Sci. 31:137.

Literature Cited

176

26. Chida, A.S., P.V.S.N. Vani and A.K. Singh. 2005. Tobacco

phytochemicals. In Alternative uses of tobacco. Central Tobacco Research

Institute, Rajahmundry. India. pp.1-15.

27. Chokshi, D. 2001. Ubiquinone composition and methods related thereto.

US Patent No. 6,806,069.

28. Chortyk, O.T. and W.S. Schlotzhauer. 1973. Studies on the pyrogenesis of

tobacco smoke constituents. (A review). Beir.Tabakforsh.Int. 7:165.

29. Cibney, B.R., F. Daldal and C.C. Moser. 2000. Coenzyme Q oxidation

reduction reactions in mitochondrial electron transport in Coenzyme Q:

Molecular mechanisms in health and disease, V.E. Kagan and P.J. Quinn

(Edn.,) CRC Press, Boca Raton, p.65.

30. Clarot, I., A. Regazzeti, N. Auzeil, F. Laadani, M. Citton, P. Netter and A.

Nicolas. 2005. Analysis of neomycin sulfate and framycetin sulfate by

HPLC-ELSD. J. Chromatogr. A 1087: 236.

31. Coles, L. and S. Harris. 1996. Coenzyme Q10 and lifespan extension.

Advances in Anti-Ageing Medicine. 1 (1): 205–215.

32. Colowick, S.P., and N.O. Kaplan. 1975. Ubiquinone group. In Methods in

Enzymology, Vol.18C, Academic Press, New York. pp.137-232.

33. Cook, C.E., E. Margaret, C.R. Tallent, I. Harper, G. Heunisch, J.B. Lewis

and M.E. Wall. 1969. An examination of the hexane extract of flue-cured

tobacco involving gel permeation chromatography. Phytochem. 8: 1025-

1033.

34. Crane, F. L. 2001. Biochemical functions of coenzyme Q10. J. Am.

College. of Nutrition. 20: 591-598.

35. Crane, F.L., Y. Hatefi, R.I. Lester and C. Widmer. 1957. Isolation of a

quinine from beef heart mitochondria. Biochimica. Biophys. Acta, Vol. 25,

pp.220-221.

36. CRC Atlas. 1975. CRC Atlas of spectral data and physical constituents of

organic compounds (J.G. Grasselli and W.M. Ritchey, Eds.), Vol.4. CRC

Press, Ohio. p.524.

37. Davis, D.L. 1976. Waxes and lipids in leaf and their relationship to smoking

quality and aroma. Rec. Adv. Tob. Sci. 2: 80-111.

Literature Cited

177

38. Deki, M. 1977. Determination of solanesol in tobacco extracts by thin layer

chromatography and high pressure liquid chromatography. Kanzei Chuo

Bunsekhishoho 17:9-16. Chem.Abst. 87:19178g.

39. Dickson, S.A., Panacea and Precious Bane, Tobacco in 16th

Century

Literature. New York Public Library, New York, 1954.

40. DiMauro, S. and M. Hirano. 1998. Mitochondria and heart disease. Curr

Opin. Cardiol. 13:190-197.

41. Doig, S.D., A. Dip and F. Baganz. 2005. Characterisation of a novel

miniaturised bubble column bioreactor for high throughput cell cultivation.

Biochem. Eng. J. 23: 97-105.

42. Du, Q. and W. Daijie. 2006. Preparation of solanesol from a tobacco leaf

extract using high speed countercurrent chromatography. J. Liq.

Chromatogr. Relat. Technol. 29: 2587-2592.

43. Duan, W.G., X.P. Chen and X. An. 2000. Methods of extracting solanesol

from tobacco. J.Chem. Ind. Forest Products, 34(2): 21–25.

44. Durbin, R.D. (Ed.) 1979. Nicotiana: Procedures for experimental use

USDA. Tech.Bull. 1586: 2.

45. Dutton, P.L., T. Ohnishi, E. Darrouzet, M.A. Leonard, R.E. Sharp, B.R.

Cibney, F. Daldal and C.C. Moser. 2002. Molecular Mechanisms in Health

and Disease, CRC Press, 65-82

46. Edlund, P.O. 1988. Determination of coenzyme Q10, α-tocopherol and

cholesterol in biological samples by coupled-column liquid

chromatography with coulometric and ultraviolet detection. J. Chromatogr.:

Biomed. Appl. 425: 87.

47. Eisai Co., Ltd. Jpn. Kokai Tokkyo Koho JP 82, 59,808, 1982.

48. Ellington, J.J., P.F. Schlotzhauer and A.I. Schepartz. 1978a. Quantification

of hexane extractable lipids in serial samples of flue-cured tobaccos. J.

Agric. Fd. Chem. 26: 270-273.

49. Ellington, J.J., P.F. Schlotzhauer and A.I. Schepartz. 1978b. Lipid

distribution in flue-cured tobacco plants. J. Agric. Fd. Chem. 26: 407-410.

50. Erickson, R.E., C.H. Shunk, N.R. Trenner, B.H. Arison and K. Folkers.

1959. Coenzyme Qx. I. Structure of solanesol. J. Amer. Chem. Soc. 81:

4999-5000.

Literature Cited

178

51. Ernster, L. 1977. Facts and ideas about the function of coenzyme Q10 in the

Mitochondria. In: Biomedical and Clinical Aspects of Coenzyme Q. K.

Folkers and Y.Yamamura (Eds.). Elsevier press, Amsterdam, pp.15-18.

52. Ernster, L. and G. Dallner. 1995. Biochemical, physiological and medical

aspects of ubiquinone function. Biochimica. Biophys. Acta. 1271(1):

195–204.

53. Finckh, B., A. Kontush, J. Commentz, C. Hubner, M. Burdeleski and A.

Kohlschutter. 1999. Methods in Enzymology (P.Packer, Ed.), Academic

Press, San Diego, Vol. 299, p.341.

54. Finckh, B., A. Kontush, J. Commentz, C. Hubner, M. Burdeleski and A.

Kohlschutter. 1995. Monitoring of ubiquinol-10, ubiquinone-10,

carotenoids, and tocopherols in neonatal plasma micro samples using high-

performance liquid chromatography with coulometric electrochemical

detection. Anal. Biochem. 232: 210.

55. Folkers, K. et al. 1974. Effect of Coenzyme Q on serum levels of creatine

phosphokinase in preclinical muscular dystrophy. Proc. of the National

Academy of Sciences, USA. 71(5): 2098.

56. Folkers K., S. Vadhanavikit and S.A. Mortensen. 1985. Biochemical

rationale and myocardial tissue data on the effective therapy of

cardiomyopathy with coenzyme Q10. Proc. Natl. Acad. Sci., U.S.A., 82 (3):

901-904.

57. Folkers, K. and A. Wolaniuk. 1985. Research on CoQ10 in clinical medicine

and in immuno modulation. Drugs. Exp. Clin. Res. 11: 539-545.

58. Folkers, K. et al. 1986. Therapy with Coenzyme Q10 for muscle dystrophy

and neurogenic atrophies by double blind trial. In Biomedical and Clinical

Aspects of Coenzyme Q (K. Folkers and Y. Yamamura Eds.). Vol. 5.

Elsevier Press, Amsterdam. pp.353-358.

59. Folkers, K., G.P. Littarru and T. Yamagami, (Eds). 1991a. Biomedical and

Clinical Aspects of Coenzyme Q, Vol. 6, Elsevier Press, Amsterdam, pp 3.

60. Folkers, K., T. Hanioka, L. Xia, J. McReejr and P. Langsjoen. 1991b.

Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects

and relevance to patients having the AIDS related complex. Biochem. and

Biophys. Res. Commun. 176(2): 786-791.

Literature Cited

179

61. Folkers, K., M. Morita and Jr.J. McRee. 1993. The activities of Coenzyme

Q10 and Vitamin B6 for immune responses. Biochem. and Biophys. Res.

Commun. 193: 88-92.

62. Fosslien, E. 2001. Mitochondrial medicine—molecular pathology of

defective oxidative phosphorylation. Ann. Clin. Lab Sci. 31(1): 25-67.

63. Fu, Q., C. Jiang and S. Ma. 1995. Method for extracting solanelic alcohol

from tobacco and apparatus thereof. Chin. Pat. No. CN 1108641.

64. Fukawa, H., M. Toyoda, T. Shimizu and M. Murohashi. 1966. Isolation of

new isoprenyl alcohols from silkworm feces. Tetrahedron Lett. 49:6209-

6213.

65. Fuke, C., S.A. Krikorian and R.R. Couris. 2000. Coenzyme Q10: A review

of essential functions and clinical trials. US Pharmacist 25: 1-12.

66. Fukusaki, E., S. Takeno, T. Bamba, H. Okumoto, H. Katto, S. Kajiyama

and A. Kobayashi. 2004. Biosynthetic pathway for the C45 polyprenol,

solanesol in tobacco. Biosci. Biotechnol. Biochem. 68:1988-1990.

67. Gaby, A.R. 1996. The role of coenzyme Q10 in clinical medicine: Part II.

Cardiovascular disease, hypertension, diabetes mellitus, and infertility.

Altern. Med. Rev. 1: 168-175.

68. Ghirlanda, G., A. Oradei, A. Manto, S. Lippa, L. Uccioli, S. Caputo, A.V.

Greco and G.P. Littarru. 1993. Evidence of plasma CoQ10-lowering effect

by HMG-CoA reductase inhibitors: Double-blind, placebo-controlled study.

J. Clin. Pharmacol. 33(3): 226-229.

69. Gold, D.R. and B.H. Cohen. 2001. Treatment of mitochondrial cytopathies.

Semin Neurol. 21: 309-325.

70. Gopalachari, N.C. 1984. Tobacco. Indian Council of Agricultural Research,

New Delhi. pp.200-235.

71. Gray, J.G., S.D. Kung, S.G. Wildman and S.J. Sheen. 1974. Origin of

Nicotiana tabacum detected by polypeptide composition of fraction I

protein. Nature 252: 226-227.

72. Greenberg, S. and W.H. Frishman. 1990. Coenzyme Q10: A new drug for

cardiovascular disease. J. Clin. Pharmacol. 30: 596-608.

Literature Cited

180

73. Grossi, G., A.M. Bargossi, P.L. Fiorella and S. Piazzi. 1992. Improved

high-performance liquid chromatographic method for the determination of

coenzyme Q10 in plasma. J. Chromatogr. 593: 217-226.

74. Grossman, J.D., R.M. Ikeda, E.J. Deszyck and A. Barley. 1963. Mechanism

of solanesol breakdown during pyrolysis. Nature 199: 661-663.

75. Guan, H.X. 2006. Method for extracting high-purity solanesol. Chin. Pat.

No. CN 1817834.

76. Hamamura, K., I. Yamatsu, N. Minami, Y. Yamagishi, Y. Inai, S. Kijima

and T. Namamura. 2002. Synthesis of [13’-14

C] coenzyme Q10. J. Label

Compd. Radiopharm. 45: 823.

77. Hanaki, Y. et al. 1991. Ratio of low-density lipoprotein cholesterol to

ubiquinone as a coronary risk factor. New England J. of Medicine 325:

814-815.

78. Hans, R.L. 1998. Coenzyme Q10 – The wonder nutrient. International

Journal of Alternative and Complementary Medicine 16(2): 11-12.

79. Henriksen, J.E., C.B. Andersen, O. Hother-Nielsen, A. Vaag, S.A.

Mortensen and H. Beck-Nielsen. 1999. Impact of ubiquinone (coenzyme

Q10) treatment on glycaemic control, insulin requirement and well-being in

patients with Type 1 diabetes mellitus. Diabet. Med. 16(4): 312-318.

80. Hermann, D.D. 2002. Naturoceutical agents in the management of

cardiovascular disease. Am. J. Cardiovasc. Drugs 2: 173-196.

81. Huang, J. and S. Zheng. 2003. Faming Zhuanli Shenqing Gongkai

Shuomingshu. CN1395939 A.

82. Huie, C.W. 2002. A review of modern sample preparation techniques for

the extraction and analysis of medicinal plants. Anal. Bioanal. Chem.

373:23-30.

83. ICH 2005. Validation of analytical procedures: Text and methodology,

(International Conference on Harmonisation of Technical Requirements for

Registration of Pharmaceuticals for Human use), Geneva, Switzerland,

Q2A (R1).

84. Ishii, N., N. Senoo-Matsuda, K. Miyake, K. Yasuda, T. Ishii, P.S. Hartman

and S. Furukawa. 2004. Coenzyme Q10 can prolong C. elegans lifespan by

lowering oxidative stress. Mechanisms of Ageing and Development. 125

(1): 41–46.

Literature Cited

181

85. Ivanov, N. and I.Ognyanov. 1966. Proc.4th

Int. Tob. Sci. Congress: 779.

J. Cancer Res. 81(11): 1184.

86. Jiang, P., M. Wu, Y. Zheng, C. Wang, Y. Li, J. Xin and G. Xu. 2004.

Analysis of coenzyme Q10 in human plasma by column-switching liquid

chromatography. J. Chromatogr. B. 805: 297–301.

87. Jolliet, P., N. Simon, J. Barre, J.Y. Pons, M. Boukef, B.J. Paniel and J.P.

Tillement. 1998. Plasma coenzyme Q10 concentrations in breast cancer:

prognosis and therapeutic consequences. Int. J. Clin. Pharmacol. Ther. 36

(9): 506-509.

88. Jones, K., K. Hughes, L. Mischley and D.J. McKenna. 2004. Coenzyme

Q10 and cardiovascular health. Altern. Ther. Health Med. 10: 22-31.

89. Judy, W.V. et al. 1993. Myocardial prevention by therapy with Coenzyme

Q10 during heart surgery. Clin. Invest. 71(Supp.): 155-161.

90. Kaneka Nutrients. Q10 Products. http://kanekaq10.com. Accessed April

2008.

91. Kang, B.K., J.S. Lee, S.K. Chon, S.Y. Jeong, S.H. Yuk, G. Khang, H.B.

Lee and S.H. Cho. 2004. Development of self-micro emulsifying drug

delivery systems (SMEDDS) for oral bioavailability enhancement of

simvastatin in beagle dogs. Int. J. Pharm. 274: 65-73.

92. Karpińska, J. and B. Mularczyk. 2004. The analysis of the zero-order and

the second derivative spectra of retinol acetate, tocopherol acetate and

Coenzyme Q10 and estimation of their analytical usefulness for their

simultaneous determination in synthetic mixtures and pharmaceuticals.

Spectrochim. Acta 60A: 2189.

93. Karpinska, J., B. Mikoluc, R. Motkowski, J. Piotrowska-Jastrzebska. 2006.

HPLC method for simultaneous determination of retinol, a-tocopherol and

coenzyme Q10 in human plasma. J. Pharm. Biomed. Anal. 42: 232–236.

94. Keca, M., S. Gross, I. Malnar, Z. Kalodera and R. Malojcic. 1997. Isolation

of solanesol from tobacco (Nicotiana tabacum L.) by classical extraction

and ultrasound extraction. Farm. Glas. 53(6): 173-182.

95. Khatta, M., B.S. Alexander, C.M. Krichten. 2000. The effect of coenzyme

Q10 in patients with congestive heart failure. Ann. Intern. Med. 132: 636–

640.

Literature Cited

182

96. Khidyrova, N.K. and K.M. Shakhidoyatov. 2002. Plant polyprenols and

their biological activity. Chem. Nat. Comp. 38.

97. Kieburtz, K. 2001. [The Huntington Study group]. A randomized, placebo-

controlled trial of coenzyme Q10 and remacemide in Huntington’s disease.

Neurology 57: 397.

98. Kishi, T., T. Watanabe and K. Folkers. 1977. Bioenergetics in clinical

medicine XV. Inhibition of Coenzyme Q10-enzymes by clinically used

adrenergic blockers of beta-receptors. Res. Commun. Chem. Pathol.

Pharmacol. 17(1): 157-164.

99. Kishi, H., N. Kanamori, S. Nisii, E. Hiraoka, T. Okamoto and T. Kishi.

1964. Metabolism and exogenous Coenzyme Q10 in vivo and bioavailability

of Coenzyme Q10 preparations in Japan. Biomedical and Clinical Aspects of

Coenzyme Q. Elsevier Press., Amsterdam. P.131-142.

100. Lagendijk, J., J.B. Ubbink and W.J. Vermaak. 1996. Measurement of the

ratio between the reduced and oxidized forms of coenzyme Q10 in human

plasma as a possible marker of oxidative stress. J. Lipid Res. 37: 67-75.

101. Lang, J.K. and L. Packer. 1987. Quantitative determination of vitamin E

and oxidized and reduced coenzyme Q by high-performance liquid

chromatography with in-line ultraviolet and electrochemical detection. J.

Chromatogr. A 385: 109-117.

102. Leffingwell, J. 2001. Chemical constituents of tobacco leaf and

differences among tobacco types. Leffingwell Reports Vol.1: 2.

103. Li, L., D. Pabbisetty, P. Carvalho, M.A. Avery and B.A. Avery. 2008.

Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography

mass spectrometry after oral administration. J. Pharm. Biomed. Anal. 46:

137-142.

104. Lieberman, A., K. Lyons, J. Levine and R. Myerburg. 2005. Statins,

cholesterol, coenzyme Q10, and Parkinson's disease. Parkinsonism Relat.

Disord. 11: 81-84.

105. Lindgren, B.O. 1965. Homologus aliphatic C30-C45 terpenols in birch wood.

Acta Chem. Scand. 19(6): 1317-1326.

106. Lipshutz, B.H., A. Lower, V. Berl, K. Schein and F. Wetterich. 2005. An

improved synthesis of the "miracle nutrient" coenzyme Q10. Organic Letters

7(19): 4095-4097.

Literature Cited

183

107. Lipshutz, B.H, P. Mollard, S.S. Pfeiffer and W. Chrisman. 2002. A short,

highly efficient synthesis of coenzyme Q10. J. Am. Chem. Soc. 124 (48):

14282 -14283.

108. Lísa, M., M. Holcapek, T. Rezanka and N. Kabátová. 2007. High

performance liquid chromatography-atmospheric pressure chemical

ionization mass spectrometry and gas chromatography-flame ionization

detection characterization of Delta5-polyenoic fatty acids in triacylglycerols

from conifer seed oils. J. Chromatogr. A 1146: 67-77

109. Littarru, G.P., L. Ho and K. Folkers. 1972. Deficiency of Coenzyme Q10 in

Human heart disease. Part I and II. Internat. J. Vit. Nutr. Res., 42/2: 291,

42/3: 413.

110. Liu, H., J. Fang, J. Jin, W. Zhong and Z. Ye. 2008. Isolation,

characterization and fermentation condition of coenzyme Q10 producing

strain with solanesol as precursor. Acta Microbiol. Sin. 48 (2): 157-163.

111. Lockwood, K., S. Moesgaard and K. Folkers. 1994. Partial and complete

regression of breast cancer in patients in relation to dosage of coenzyme

Q10. Biomed. and Biophys. Res. Commun. 199: 1504-1508.

112. Lopez Lorenzo, P., B. Sanzperez and J. Burgos. 1962. Unsaponifiable

fractions of cream fat and butter fat. Anales Bromatol (Madrid) 14: 205-

219. Chem. Abst. 59: 1851 (1963).

113. Luque, de Castro, M.D. and L.E. Garcia-Ayuso. 1998. Soxhlet extraction of

solid matrices: An outdated technique with promosing innovative future.

Anal. Chim. Acta. 369: 1.

114. Ma, S. and K. Xu. 2002. Process for purifying solanesol. Chin. Pat. No. CN

1345711.

115. Mamura, Y., K. Folkers and Y. Ito. Biochemical and Clinical Aspects of

Coenzyme Q10: Elsevier press, Amsterdam, 1977a, 1980b, 1981c, 1983d,

Vol. IIb, IIIc, IVd.

116. Marz, W. and H. Wieland. 2000. HMG-CoA reductase inhibition: Anti-

inflammatory effects beyond lipid lowering ? 25 (2): 117-125.

117. Massie, I.E. 1981. Tobacco leaf–A look at history. Rec. Adv. Tob. Sci.7:

3-18.

Literature Cited

184

118. Matthews, R.T., L. Yang, S. Browne, M. Baik and M.F. Beal. 1998.

Coenzyme Q10 administration increases brain mitochondrial concentrations

and exerts neuroprotective effects. Proc. Natl. Acad. Sci. 95: 8892-8897.

119. Mayo Clinic Drugs and Supplements: Coenzyme Q10. 2008.

120. Megoulas, N.C. and M.A. Koupparis. 2004. Enhancement of evaporative

light scattering detection in high-performance liquid chromatographic

determination of neomycin based on highly volatile mobile phase, high-

molecular-mass ion-pairing reagents and controlled peak shape. J.

Chromatogr. A. 125.

121. Mellors, A. and A.L. Tappel. 1966a. Quinones and quinols as inhibitors of

lipid peroxidation. Lipids Vol.1, pp. 282-284.

122. Mellors, A. and A.L. Tappel. 1966b. The inhibition of mitochondrial

peroxidation by ubiquinone and ubiquinol. J. Biol. Chem., Vol. 241, pp.

4353-4356.

123. Michalkiewicz, S. 2008. Voltammetric determination of coenzyme Q10 in

pharmaceutical dosage forms. Bioelectrochemistry 73: 30.

124. Mitchell, P. 1976. Possible molecular mechanisms of the protonmotive

function of cytochrome systems. J. Theoret. Biol. 62: 327.

125. Mitchell, P. 1979. Kelin's respiratory chain concept and its chemiosmotic

consequences. Science. 206: 1148.

126. Mitchell, P. 1988. Respiratory chain systems in theory and practice. In

Advances in Membrane Biochemistry and Bioenergetics, (Kim C.H., et al.

Eds.), Plenum Press, New York, pp. 25.

127. Mitchell, P. 1991. The vital protonmotive role of coenzyme Q. In:

Biomedical and Clinical Aspects of Coenzyme Q, Folkers K., Littarru G.P.,

Yamagami T. (Eds) Vol. 6, Elsevier Press, Amsterdam, pp.3-10.

128. Mitsui Toatsu Chemicals, Inc. Jpn. Kokai Tokkyo koho JP 80,118,437;

1980. CA: 94:139993k.

129. Mold, J.D. and J.S. Booth. 1957. Isolation of solanesol from cigarette

smoke. Tob. Sci. 1: 38-39.

130. Moll, H. 1926. The treatment of post-encephalitig Parkinsonism by

nicotine. British Medical J. 1079-1081.

Literature Cited

185

131. Mortensen, S. A., A. Leth, E. Agner and M. Rohde. 1997. Dose-related

decrease of serum coenzyme Q10 during treatment with HMG-CoA

reductase inhibitors. Mol Aspects Med.18 (Suppl): S137-144.

132. Morton, R.A., G.M. Wilson, J.S. Lowe and W.M.F. Leat. 1957.

Ubiquinone. Chemical Industry. pp.1649.

133. Mosca, F., D. Fattorini, S. Bompadre and G. P. Littarru. 2002. Assay of

coenzyme Q10 in plasma by a single dilution step. Anal. Biochem. 305: 49.

134. Muller, T., T. Buttner, A.F. Gholipour and W. Kuhn. 2003. Coenzyme Q10

supplementation provides mild symptomatic benefit in patients with

Parkinson's disease. Neurosci. Lett. 341: 201-204.

135. Muruyama, K. and Y. Naruta. 1978. Synthesis of naturally occurring

quinones. Part 3. Allylation of quinones with allyltin reagents.

New synthesis of coenzyme Q1 and plastoquinone-1. J. Org. Chem. 43:

3796-3798.

136. Nagaraj, G. 1976. Composition studies of lipophilic constituents of natu

tobacco (indigenous to India), Ph.D Thesis, Sri Venkateswara University,

Tirupati, India.

137. Nagaraj, G. and M.K. Chakraborty. 1978. Lipophilic constituents of natu

tobacco: Fractionation and isolation. Tob. Res. 4: 37-40.

138. Narasimha Rao, C.V. and M.K. Charkraborty. 1978. Phytochemicals from

tobacco wastes. I. Survey of raw material. Tob. Res. 4: 52-58.

139. Narasimha Rao, C.V. and M.K. Chakraborty. 1979. Solanesol from

tobacco waste. Research and Industry. 24: 83-86.

140. Narasimha Rao, C.V., S.R. Prabhu, K. Mahendra, Shefali Srivastava,

Kanwal Raj and A.P. Bhaduri. 2000. Reverse phase HPLC analysis of

solanesol. Paper presented at the National Symp on Tobacco, December

13-16, 2000, Indian Society of Tobacco Science, Rajahmundry, India, Abst.

No. C19. p 50.

141. Narasimha Rao, C.V. and S.R. Prabhu. 2005. Solanesol. In Alternative

Uses of Tobacco. Central Tobacco Research Institute, Rajahmundry.

pp.16-26.

142. Narasimha Rao, C.V. and V. Krishnamurthy. 2007. Tobacco plant:

A source of pharmaceutical and industrial products. Invention Intelligence.

42(4): 3-12.

Literature Cited

186

143. Narasimha Rao, C.V., S.R. Prabhu, K. Mahendra, Kanwal Raj,

S. Srivastava and A.P. Bhaduri. 2007. Process for purification of Solanesol

(95%+) from crude/enriched extracts of tobacco green leaf/tobacco cured

leaf/tobacco waste. Indian Patent No. IN211204.

144. Naruta, Y. and K. Maruyama, 1979. Regio and stereo-controlled

polyprenylation of quinines: A new synthetic method of coenzyme Q2, Q3,

Q9 and Q10. Chem. Lett. 885.

145. Nohl, H, A.V. Kozlov, K. Stanick and L. Gille. 2001. The multiple

functions of coenzyme Q. Bioorg. Chem. 29: 1-13.

146. Okamoto, T., T. Matsuya, Y. Fukunaga, T. Kishi and T. Yamagami. 1989.

Human serum ubiquinol-10 levels and relationship to serum lipids.

International J. for Vitamin and Nutrition Res. 59 (3): 288–292.

147. Okamoto, T., Y. Fukunaga, Y. Ida and T. Kishi. 1988. Determination of

reduced and total ubiquinones in biological materials by liquid

chromatography with electrochemical detection. J. Chromatogr. 430:

11–19.

148. Ourisson, G. 1990. The general role of terpenes and their global

significance. Pure and Appl. Chem. 62: 1401-1404.

149. Ouyang, P.K and Y.H. Hu, Prog. Chem. Eng. 4 (1994) 9 (Chinese).

150. Overvad, K., B. Diamant, L. Holm, G. Holmer, S.A. Mortensen and S.

Stender. 1999. Coenzyme Q10 in health and disease. Eur. J. Clin. Nutr. 53:

764-770.

151. Ozawa, Y., Y. Mizushima, I. Koyama, M. Akimoto, Y. Yamagata, H.

Hayashi and H. Murayama. 1986. Intestinal absorption enhancement of

coenzyme Q10 with a lipid microsphere. Drug. Res. 36(1): 689.

152. Palamakula, A. and M.A. Khan. 2004. Evaluation of cytotoxicity of oils

used in coenzyme Q10 Self-Emulsifying Drug Delivery Systems (SEDDS).

Int. J. Pharm. 273: 63-73.

153. Pastor, A., E. Vazquez, R. Ciscar and M.De.La. Guardia. 1997. Efficiency

of the microwave-assisted extraction of hydrocarbons and pesticides from

sediments. Anal. Chim. Acta. 344: 241.

154. Pennock, J.F., F.W. Hemming and R.A. Morton. 1962. Some

unsaponifiable lipids of the spadix of Arum maculatum. Biochem. J. 82: 11.

Literature Cited

187

155. Pepping, J. 1999. Coenyzme Q10. American J. of Health-System Pharmacy

56: 519-521.

156. Phani kiran, K., C.V.Narasimha Rao and Kanwal Raj. 2008. Estimation of

solanesol in tobacco and non-tobacco plants from solanaceae family.

JMAPS. 30: 105 - 108.

157. Podda, M., C. Weber, M.G. Traber, R. Milbradt and L. Packer. 1999.

Methods in Enzymology (L.Packer, Ed.), Academic Press, San Diego, Vol.

299, p.330.

158. Qunly, Y. and W. Jianhua. 2001. Process for extracting solanesol. Chin.

Pat. No. CN 1294111.

159. Qunly, Y. and W. Jianhua. 2005. Solanesol refining method. Chin. Pat. No.

CN 1676502.

160. Ratnam, D.V., V. Bhardwaj and M.N.V.R. Kumar. 2006. Simultaneous

analysis of ellagic acid and coenzyme Q10 by derivative spectroscopy and

HPLC. Talanta 70: 387.

161. Rauchova, H., Z. Drahota and G. Lenaz. 1995. Function of coenzyme Q in

the cell: Some biochemical and physiological properties. Physiol. Res.

44: 209.

162. Ravada, S.R, L.R. Emani, M.R.Garaga, B. Meka and T. Golakoti. 2009.

Synthesis of coenzyme Q10. Am. J. Infect. Dis. 2: 83-89.

163. Reid, W.W. 1974. The phytochemistry of the genus Nicotiana. The

biosynthesis of terpenoids in two varieties of N.tabaccum. Le. Tabac.

Annales. 11: 165-175.

164. Rodriguez-Estrada, M.T., A. Poerio, M. Mandrioli, G. Lercker,

A. Trinchero, M. R. Tosi and V. Tugnoli. 2006. Determination of coenzyme

Q10 in functional and neoplastic human renal tissues. Anal. Biochem.

357: 150.

165. Roffe, L., K. Schmidt and E. Ernst. 2004. Efficacy of coenzyme Q10 for

improved tolerability of cancer treatments: A systematic review. J. Clin.

Oncol. 22: 4418-4424.

166. Romanik, G., E. Gilgenast, A. Przyjanzny, J. Namiesnik and M. Kaminski.

2007. Techniques of preparing plant material for chromatographic

separation and analysis. J. Biochim. Biophys. Methods. 70: 253.

Literature Cited

188

167. Rowland, R.L., P.H. Latimer and J.A. Giles. 1956. Flue-cured tobacco I.

Isolation of solanesol, an unsaturated alcohol. J. Am. Chem. Soc. 78: 4680-

4683.

168. Rowland, R.L. and P.H. Latimer. 1959. Flue-cured tobacco. IV. Isolation of

solanesol esters. Tob. Sci. 3: 1-3.

169. Rowland, R.L., and J.A. Giles. 1960. Flue-cured tobacco V. Polyisoprenoid

compounds. Tob. Sci. 4: 29-32.

170. Ruiz-Jimenez, J., F. Priego-Capote, J.M. Mata-Granados, J.M. Quesada and

M.D.L.D.Castro. 2007. Determination of the ubiquinol-10 and ubiquinone-

10 (coenzyme Q10) in human serum by liquid chromatography tandem mass

spectrometry to evaluate the oxidative stress. J. Chromatogr. A 1175: 242.

171. Ruiz-Rodriguez, A., M.R. Bronze and M.N. Ponte. 2008. Supercritical fluid

extraction of tobacco leaves: A preliminary study on the extraction of

solanesol. J. Supercritical Fluids. 45: 171.

172. Sándor, P.S., L.D. Clemente, G. Coppola, U. Saenger, A. Fumal, D.

Magis, L. Seidel, R.M. Agosti and J. Schoenen. 2005. Efficacy of

coenzyme Q10 in migraine prophylaxis: A randomized controlled trial.

Neurology 64: 713-715.

173. Sarter, B. 2002. Coenzyme Q10 and cardiovascular disease: A review. J.

Cardiovasc. Nurs. 16(4): 9-20.

174. Sasaki, K., M. Watanabe, Y. Suda, A. Ishizuka and N. Noparatnaraporn.

2005. Applications of photosynthetic bacteria for medical fields. J. Biosci.

Bioengg. 100: 481.

175. Schlotzhauer, W.S. and I. Schmeltz. 1969. Pyrogenesis of aromatic

hydrocarbons present in cigarette smoke II. Pyrolytic products of some

representative constituents in hexane soluble fraction of tobacco. Beitr.

Tabakforsch. Intl. 4: 176.

176. Scholtzhauer, W.S., R.F. Severson, O.T. Chortyk and R.F. Arrendale. 1976.

Pyrolytic formation of polynuclear aromatic hydrocarbons from petroleum

ether extractable constituents of flue-cured tobacco leaf. J. Agric. Food

Chem. 24: 992-997.

177. Severson, R.F., J.J. Ellington, P.F. Schlotzhauer, R.F. Arrendale and A.I.

Schepartz. 1977. Gas chromatographic method for the determination of

free and total solanesol in tobacco. J. Chromatog. 139: 269-282.

Literature Cited

189

178. Severson, R.F., R.P. Arrendale, O.T. Chortyk and M.E. Snook. 1978a. A

method for determining the transfer of lipids from tobacco to smoke. Tob.

Sci. 22: 130-133.

179. Severson, R.F., J.J. Ellington, R.F. Arrendale, M.E. Snook. 1978b.

Quantitative gas chromatographic method for the analysis of aliphatic

hydrocarbons, terpenes, fatty alcohols, fatty acids and sterols in tobacco. J.

Chromatogr. 160: 155-168.

180. Sharma, S., M. Kheradpezhou, S. Shavali, H.E. Refaey, J. Eken, C. Hagen

and M. Ebadi. 2004. Neuroprotective actions of coenzyme Q10 in

Parkinson's disease. Methods in Enzymol. 382: 488-509.

181. Sheen, S.J., D.L. Davis, D.W. Dejong and J.F. Chaplin. 1978. Gas-liquid

chromatographic quantification of solanesol in chlorophyll mutants of

tobacco. J. Agric. Food Chem. 26: 259-262.

182. Shindo, Y., E. Witt, D. Han, W. Epstein and L. Packer. 1994. Enzymic and

non-enzymic antioxidants in epidermis and dermis of human skin. The J. of

Investigative Dermatology. 102 (1): 122-124.

183. Silvette, H., P.S. Larson and H.B. Haag. 1958. Medical uses of tobacco:

Past and present. Virginia Med. Monthly 85: 472-484.

184. Sinatra, S.T. 1998. The Coenzyme Q10 Phenomenon. Keats Publishing,

New Canaan, CT.

185. Singal, P.K., N. Khaper, V. Palace and D. Kumar. 1999. On the role of

coenzyme Q10 in cardiovascular diseases. Cardiovasc. Res. 43: 250.

186. Singh, R.B., M.A. Niaz, S.S. Rastogi, P.K. Shukla and A.S. Thakur. 1999.

Effect of hydro soluble coenzyme Q10 on blood pressures and insulin

resistance in hypertensive patients with coronary artery disease. J. Hum.

Hypertens. 13(3): 203-208.

187. Soja, A.M. and S.A. Mortensen. 1997. Treatment of congestive heart failure

with coenzyme Q10 illuminated by meta-analyses of clinical trials. Mol.

Aspects Med.18 (Suppl): S159-168.

188. Song, Y. and R.G. Cooks. 2006. Atmospheric pressure ion/molecule

reactions for the selective detection of nitroaromatic explosives using

acetonitrile and air as reagents. Rapid Commun. Mass Spectrum. 20: 3130.

Literature Cited

190

189. Srivatsava S., Kanwal Raj, P.Khare, A.P.Bhaduri, R.Chander, R.Raghubir,

K.Mahendra, C.V.Narasimha Rao and S.R.Prabhu. 2009. Novel hybrid

natural products derived from solanesol as wound healing agents. Indian J

Chem 48B: 1-12.

190. Stedman R.L., A.P. Swain and W. Rusaniwskyj. 1962. Composition

studies on tobacco XII. Total hexane extractives. Tob. Sci. 6: 1-3.

191. Stedman, R.L., W.R. Billinisky and A.P. Swain. 1962. Total Hexane and

ethanol extractives of tobacco. U.S.D.A. Publication, ARS, Washington,

D.C. pp.73-78.

192. Stedman, R.L. 1968. The chemical composition of tobacco and tobacco

smoke. Chem. Revs. 68:153-207.

193. Steele, P.E., P.H. Tang, A.J. DeGrauw and M.V. Miles. 2004. Clinical

laboratory monitoring of coenzyme Q10 use in neurologic and muscular

diseases. Am. J. Clin. Pathol. 121(Suppl): S113.

194. Sueda, K. and Yoshima, I. 1978. Japan Kokai, 78,50,126.

195. Suzuki, H. et al. 1990. Cytocidal activity of a synthetic isoprenoid, N-

solanesyl N, N’-bis (3,4-dimethoxybenzyl) ethylenediamine and its

potentiation of antitumor drugs against multi-drug resistant and sensitive

cells in vitro. Japan. J. Cancer Res.81 (3): 298-303.

196. Tabashi, I., Y. Kuroda, K. Fujita and H. Kawakubo. 1978. Tetrahedron

Lett. 24: 2083.

197. Takahiro, T. 1988. Purification of solanesol. Japanese Patent No. JP

63190840.

198. Takemura, M. and M. Amano. 1979. Method of gathering solanesol.

Japanese Patent No. JP54138510.

199. Tang, D.S., L. Zhang, H.L. Chen, Y.R. Liang, J.L. Lu, H.L. Liang and

X.Q. Zheng. 2007. Extraction and purification of solanesol from tobacco:

Extraction and silica gel column chromatography separation of solanesol.

Sep. Purif. Technol. 56: 291-295.

200. Tarnopolsky, M.A. and M.F. Beal. 2002. Potential for creatine and other

therapies targeting cellular energy dysfunction in neurological disorders.

Ann. Neurol. 49: 561-574.

Literature Cited

191

201. Thibault, A., D. Samid, A. Tompkins, W. Figg, M. Cooper, R. Hohl, J.

Trepel, B. Liang, N. Patronas, D. Venzon, E. Reed and C. Myers. 1996.

Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in

patients with cancer. Clinical Cancer Research: An Official Journal of the

American Association for Cancer Res. 2(3): 483-491.

202. Tomasetti, M., R. Alleva, M.D. Solenghi and G.P.Littaru. 1999.

Distribution of antioxidants among blood components and lipoproteins:

Significance of lipid/CoQ10 ratio as a possible marker of increased risk for

atherosclerosis. BioFactors. 9: 231.

203. Tomida, A. et al. 1990. Synergistic effect in culture of bleomycin group

antibiotics and N-solanesyl N,N’-bis (3,4-dimethoxybenzyl)

ethylenediamine, a synthetic isoprenoid. Jpn. J. Cancer Res. 81(11)

1184-1190.

204. Tomono, Y., J. Hasegawa, T. Seki, K. Motegi and N. Morishita. 1986.

Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man.

International J. of Clinical Pharmacology, Therapy and Toxicology.

24 (10): 536–541.

205. Toyoda, M., H. Fukawa and T. Schimidzu. 1970. Plant polyisoprenoids. I.

Plant polyisoprenoids of silkworm feces and mulberry leaf. Nippon Nogei

Kogaku Kaishi. 43:688-693. Chem. Abst. 72: 62856d (1970).

206. Toyokichi, Y., T. Hatsunori, T. Koichi and K. Toshio. 1982. Regioselective

polyprenyl rearrangement of polyprenyl 2,3,4, 5 – tetrasubstituted phenyl

ethers promoted by boron trifluoride. Chem.Lett. 1131.

207. Troje, Z.S., Z. Frobe, D. Perovic. 1997. Analysis of selected alkaloids and

sugars in tobacco extract. J. Chromatogr. A 775:101-107.

208. Turunen, M., J. Olsson and G. Dallner. 2004. Metabolism and function of

coenzyme Q. Biochim. Biophys. Acta 1660: 171-199.

209. U.S. Pharmacopeia (USP 30). 2007. National Formulary (NF 25), Asian

Edition, The official compendia of standards, Vol.1: 986.

210. US Environmental Protection Agency. 1993. Respiratory Effects of passive

smoking: Lung cancer and other disorders: The Report of the US

Environmental Protection Agency, Monograpg. 4, NIH Publication No.93-

3605. US Department of Health and Human Services. USDA. Tech. Bull.

1586: 2.

Literature Cited

192

211. Vogel, R., K. Defillipo and V. Reif. 2004. Determination of isepamicin

sulfate and related compounds by high performance liquid chromatography

using evaporative light scattering detection. J. Pharm. Biomed. Anal.

24: 405.

212. Wahlberg, I., K. Karlsson, D.J. Austin, N. Junker, J. Roerade, C.R. Enzell

and W.H. Johnson. 1977. Effects of flue-curing and ageing on the volatile

neutral and acidic constituents of Virginia tobacco. Phytochem. 16:

1217-1231.

213. Weber, C., T.S. Jakobsen, S.A. Mortensen, G. Paulsen and G. Hølmer.

1994. Antioxidative effect of dietary coenzyme Q10 in human blood plasma.

Intl. J. for Vitamin and Nutrition Res. 64(4): 311-315.

214. Wellburn, A.R. and F.W. Hemming. 1966. Gas liquid chromatography of

derivatives of naturally occurring mixtures of long chain polyisopreniod

alcohols. J. Chromatogr. 23: 51-60.

215. West, D. David and M.E. Rockport. 2004. Synthesis of coenzyme Q10,

ubiquinone, US Patent No. 6,686,485.

216. Witte, K.K., A.L. Clark and J.G. Cleland. 2001. Chronic heart failure and

micronutrients. J. Am. Coll. Cardiol. 37: 1765-1774.

217. Wolf, D.E., C.H. Hoffman, N.R. Trenner, B.H. Arison, C.H. Shunk, B.D.

Linn, J.F. McPherson and K. Folkers. 1958. Structure studies on the

coenzyme Q group. J. Am. Chem. Soc. 80: 4752.

218. Woollen, B.H. and D.H. Jones. 1971. Analytical methods for tobacco lipids.

A rapid method for the estimation of solanesol by thin-layer densitometry.

J. Chromatogr. 61: 180-182.

219. Woollen, B.H., W.J. Irvine, P.W. Brown and D.H. Jones. 1972. A Thin

layer chromatographic method for tobacco lipid analysis. Tob. Sci. 16:

101-103.

220. Wu, J. 1996. Extraction process of solanesol from tobacco with nicotine.

Chin. Pat. No. CN1115751.

221. Wu, J. and Q. Yang. 2001. Process for extracting solanesol. Chin. Pat. No.

CN 1294111.

222. Xia, S. and S. Xu. 2006. Improved assay of coenzyme Q10 from liposomes

by Tween 80 solubilisation and UV spectrophotometry. J. Sci. Food Agric.

86: 2119.

Literature Cited

193

223. Yakushina, L. and A. Taranova. 1995. Rapid HPLC simultaneous

determination of fat-soluble vitamins, including carotenoids, in human

serum. J. Pharm. Biomed. Anal. 13: 715-718.

224. Yalcin, A., E. Kilinc, A. Sagcan and H. Kultursay. 2004. Coenzyme Q10

concentrations in coronary artery disease. Clin. Biochem. 37: 706-709.

225. Yamashita, S. and Y. Yamamoto. 1997. Simultaneous detection of

ubiquinol and ubiquinone in human plasma as a marker of oxidative stress.

Anal.Biochem. 250: 66-73.

226. Yuan, J. and H. Wei. 2004. Amino Acids Biot. Resour. 26: 53 (Chinese).

227. Zhang, D. 1991. Process for preparing solanesol from mouldy tobacco or

tobacco waste. Chin. Pat. No. CN 1056486.

228. Zhang, D. and H. Zhang. 1994a. Process for extracting solanesol from

mouldy and broken tobacco. Chin. Pat. No. CN 1087076.

229. Zhang, D. and H. Zhang. 1994b. Process for preparing unsaponifiable

matter of solanesol. Chin.Pat. No. CN 1094705.

230. Zhang, W., T. Shi and W. Xing. 1996. Method for producing solanesol.

Chin. Pat. No. CN 1118775.

231. Zhang, Z., Y.K. Wu, H.C. Yin, J. Lin. 2005. Yunnan Univ. 27:157-160.

232. Zhao, G., J. Qu, M. Liu, K. Liu, and Z. Du. 2002. Application of chemical

modified electrode in coulometric titration for determination of solanesol.

Anal. Lett. 35: 785-795.

233. Zhao, J., C. Wang and X. Sun. 1997. Determination of solanesol in the

extracts of tobacco leaves by high performance liquid chromatography.

Chinese J. Chromatogr. 15 (6): 544–547.

234. Zhao, J. and Q. Du. 2007. Separation of solanesol in tobacco leaves extract

by slow rotary counter-current chromatography using a novel non-aqueous

two-phase solvent system. J. Chromatogr. A 1151: 193-196.

235. Zhou, H.Y. and C.Z. Liu. 2006. Microwave-assisted extraction of solanesol

from tobacco leaves. J. Chromatogr. A 1129: 135.

236. Zhoua, H.Y. and C.Z. Liu. 2006. Rapid determination of solanesol in

tobacco by high-performance liquid chromatography with evaporative light

scattering detection following microwave-assisted extraction. J.

Chromatogr. B 835: 119-122.