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Editor-in-chief:V.T.Ivashkin

Production Manager:G.G.Piskunov

Editorial Manager:T.L.Lapina(E-mail: good.day@ru.net)

Editorial board:Ye.K.BaranskayaA.O. BueverovS.A.BulgakovP.S.VetshevG.I.VorobievA.V.Kalinin (deputy editor-in-chief)Z.A.LemeshkoA.F.LoginovI.V.MayevM.V.MayevskayaYu.M.PantsyrevL.M.PortnoyS.I.RapoportV.V.SerovYu.V.TelnykhA.S.TroukhmanovA.I.KhazanovS.A.ChernyakevichA.A.Sheptulin (deputy editor-in-chief)

Editorial council:S..Alexeyenko KhabarovskV.M.Arutyunyan YerevanO.Ya.Babak KharkovE.I.Byeloborodova TomskE.G.Grigoryan YerevanA.K.Yeramishantsev MoscowYe.I.Zaytseva SmolenskA.R.Zlatkina MoscowG.F.Korotko KrasnodarS.A.Kurilovich NovosibirskV.A.Maximov MoscowS.N.Mammaev MachachkalaYu.Kh.Marakhovsky MinskG.A.Minasyan YerevanO.N.Minushkin MoscowI.A.Morozov MoscowYu.G.Mukhina MoscowA.I.Pal'tsev NovosibirskL.K.Parkhomenko KharkovV.D.Pasyechnikov StavropolS.D.Podymova MoscowG.V.Rimarchuk MoscowV.I.Simonenko Saint-PetersburgA.V.Tkachev Rostov-on-DonYe.D.Fedorov MoscowI.L.Khalif MoscowG.V.Tsodikov MoscowA.V.Shaposhnikov Rostov-on-Don

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:..(E-mail: good.day@ru.net)

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3 16 2006

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: -E-mail: rm-vesti@mtu-net.ru

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: 73538

15.12.1994 . ( 013128)

www.m-vesti.ru

:119992, ,. , . 1, . 1 , ,,

: (495)248-38-23(E-mail:good.day@ru.net)

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Russian Journal of Gastroenterology, Hepatology, Coloproctology

Volume 16 3 2006

2

.., .., .., .., .., .. : - . . . . . . . . . . . . . . . . . . . .4

.. : - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12

.., .., .. - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17

.., .., .. ( 3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24

.., .., .., .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30

.., .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .36

.., .., .., .. . . . . . . . . . . . . . . . . . . . . . . . . .40

, .. Helicobacter pylori . . . . . . . . . . . . . . . . . . . . .45

.., .. H. pylori- ( ) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52

.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58

.., .., .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62

.., .., .. . . . . . . . . . . . . . . . . . . . . . . . .68

.., .., .., .., .. 13- H. pylori- . . . . . . . . . . . . . . . . . . . .77

.., .., .. . . . . . . . . . . . . . . . . . . . . . . . . . . .85

.., .., .., .., .., .., .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .89

n t e n t sn t e n t s

3

The lectures and reviewsKardasheva S.S., Kogan Ye.A., Ivashkin V.T., Sklyanskaya O.A., Demura T.A., Trukhmanov A.S.Development of dysplasia and cancer at esophagitis and Barrett's esophagus: clinical and morphological parallels . . . . . . . . . . . . . . . . . . . . .4

Kononov A.V.Cytoprotection of the stomach mucosa: molecular and cellular mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12

Original investigationsUsik S.F., Osadchuk M.A., Kalinin A.V.Clinical, endoscopic and morpho-functional parameters in evaluation of the course of gastroesophageal reflux disease in various age groups . . . . . . . . . . . . . . . .17

Plyusnin S.V., Khazanov A.I., Yazenok N.S.Comparison of antiviral drugs in treatment of chronic viral hepatitis C (genotype 3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24

Syutkin V.Ye., Shipov O.Yu., Petukhova S.V., Ivanikov I.O.Non-invasive diagnostics of active alcoholic hepatitis in patients with liver cirrhosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30

Kovaleva N.B., Bayramova I.Kh.Intrahepatic cholestasis of pregnancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .36

Kulinsky V.I., Leonova Z.A., Kozlova N.M., Kolesnichenko L.S.Glutathione system in erythrocytes and blood plasma at chronic diseases of the gallbladder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40

National college of gastroenterologists, hepatologistsZakharova N.V.The combined mode of Helicobacter pylori eradication . . . . . . . . . . . . . . . . . . . . . . . . .45

Pasechnikov V.D., Chukov S.Z.Premalignant changes of the stomach and eradication therapy potential for prophylaxis of the H.pylori-associated stomach cancer (Review of the literature) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52

News of coloproctologyKhalif I.L.Medical tactics at ulcerative colitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58

Perekhodov S.N., Lazarev G.V., Tatarin V.S.Sphincter-preserving operations at the treatment of rectal cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62

Exchange of experienceMayev I.V., Troukhmanov A.S., Kucheryavy Yu.A.Pharmacoeconomics of acid-related diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .68

Ivashkin V.T., Stepanov Ye.V., Baranskaya Ye.K., Lapshin A.V., Sklyanskaya O.A.Interrelation of the laser 13-urease breath test results and morphological state of a gastroduodenal mucosa in various the H. pylori-associated diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .77

Bulanova Ye.L., Drapkina O.M., Libet Ya.A.ECG dynamics at electrolyte disorders in patient with terminal liver failure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .85

Geyvandova N.I., Kastornaya I.V., Yagoda A.V., Aksyonenko V.A., Gavrilova L.B., Gudzovskaya T.V., Koroy P.V.Case of liver peliosis as a result of long-term intake of Aevitum preparation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .89

4

3, 2006

- - - - - . - 9- - 7- , - - - - [3, 9]. 50%[10]. 5- - 15%, - / - ( 3075%) [26, 43]. , , , 5- - 63% [26].

. 1950 . N.R. Barrett - , - . 70- Trier Paul -: , - -

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6

3, 2006

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7

3, 2006

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8

3, 2006

- (.. ,.. , 2003), - () - / 2 . , . - - () - -, . - 4- - 2 . - . - - 6 , - . 3 , 1 - . , , - . , - - .

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