الرحمن الله بسمالرحیم

Muscular systemMuscular systemMuscular systemMuscular system

Type of Muscles

•Skeletal Muscle•Cardiac Muscle•Smooth Muscle

Diameter of Skeletal Muscle

• Specific Muscle• Age• Sex• State of Nutrition• Physical Training HypertrophyHyperplasia

Organization of Skeletal Muscle

Skeletal Muscle

Organization of Skeletal Muscle

Organization of

Skeletal Muscle Fiber

Cross Striation

Myofilaments

•Thin filamentActinTropmyosinTroponin•Thick filamentMyosin

G Actin

Thin Filament

F Actin

Troponin

Tropomyosin

Thin filament

Thick Filament

Myosin

Actin & myosin

• Summary Slide

Myosin

Actin & myosin

• Summary Slide

Organization of the Myofilaments

Myofilaments

• T Tubule• Terminal Cisternae• Sarcoplasmic

Reticulum• Triad

Sarcolamma &

Sarcoplasmic Reticulum

•triad

Transmission of the signal to SER

Contraction Mechanism

Contraction

mechanism

Myofilaments

Myotendineal Junction

Innervation

Myasthenia Gravis• Autoimmune Disorder• Prograssive mascular weakness• Reduction of acetylcholin

receptors

Type of skeletal muscle

•Type I: slow, red oxidative fibers

many mitochondria and myoglobinGain energy by aerobic oxidative

phosphorilationProlong contractionBack muscle

Type of skeletal muscle• Type IIa:fast, intermediate oxidative-

glycolytic fibermany mitochondria and myoglobinConsiderable glycogenBoth oxidative and anaerobic glycolysisRapid contraction short burst of activity

Type of skeletal muscle• Type IIb: fast , white glycolytic

fibers fewer mitochondria, less

myoglobin and abundant glycogenDepend on glycolysisAdapt for rapid contraction

Skeletal muscle types

• Myogenesis(Straited Muscle)

Muscle Spindle

• Intrafusal muscle fibers

Nuclear chain fibers

Nuclear bag fibers• Extrafusal muscle

fibers

Cardiac Muscle

Cardiac Muscle

Cardiac Muscle

Cardiac Muscleintercalated Disc

Cardiac Muscle

Diad &IntercalateddiscIn CardiacMusclecell

Smooth muscle

Smooth Muscle

Smooth muscle

contraction

SmoothMusclecell

Smooth Muscle

Contraction mechanism