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    COVER

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    “Encountering Global Challenges through Innovation on Science,

    Technology, Engineering, and Mathematics (STEM), and Education”

    Copyright © 2017 Faculty of Mathematics and Natural Sciences Ganesha University of Education

    Editors Dr. I Wayan Puja Astawa, S.Pd, M.Stat.Sci Alexander Korinus Marantika, S.Pi, M.P I Gusti Ngurah Yudi Handayana, S.Pd, M.Sc Putu Kartika Dewi, S.Pd, M.Sc Ni Putu Ayu Hervina, S.Pd, M.Pd Cover Design Laba Laksana Printed by Universitas Pendidikan Ganesha Press Jalan Udayana 11 Singaraja Bali Telp. (0362) 22570

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    CONFERENCE PROGRAM INTERNATIONAL CONFERENCE ON MATHEMATICS AND NATURAL SCIENCES (IConMNS) 2017

    https://itembrowser.com/item.php?id=841 Denpasar, September 6th – 7th, 2017

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    TABLE OF CONTENTS COVER ................................................................................................................................................ i

    CONFERENCE PROGRAM ...................................................................................................... iii

    COMMITTEE .............................................................................................................................. xiii

    WELCOME ADDRESS : CHAIR OF THE COMMITTEE ............................................. xiv

    OPENING ADDRESS: RECTOR OF UNIVERSITAS PENDIDIKAN GANESHA .................................................................................................................................... xvi

    RUNDOWN OF IConMNS 2017 ......................................................................................... xix

    PARALLEL SESSION SCHEDULE OF ICONMNS 2017 ...............................................xx

    KEYNOTE SPEAKERS’ PAPER ...................................................................................... xxxiii

    Surprising -Diketonate Metal Chemistry ...................................................................... 1

    Challenges In The Design Of Coordination Polymers Of The Zinc-Triad 1,1-Dithiolates............................................................................................................... 22

    On The Analysis Of Transversal Oscillations In Axially Moving Continua ....................................................................................................................................... 32

    Dielectric Relaxation and Ionic Conductivity of a Chitosan/Poly(ethylene oxide) Blend Doped with Potassium and Calcium Cations ......................................................................................................................... 44

    INVITED SPEAKERS’ PAPER ............................................................................................... 63

    Students' Interaction Pattern In Online Learning: A Study At Educational Chemistry Department, State University Of Malang ..................... 64

    Silicon Chemistry For Sustainable Development Of Rice Agriculture ............ 65 A Sirs Model For Transmission Of Dengue Fever Disease In South Sulawesi ........................................................................................................................................ 81

    Didactical Design Of Integers: An Elementary School Teachers Creation Viewed From Theory Of Didactical Situation ............................. 91

    Development Of Low Sidelobe Level Array Antenna For Synthetic Aperture Radar Sensor .......................................................................................... 102

    Green Electronics and Energy Harvesting Using Natural Organics Product: Current Progress and Its Potential ............................................... 111

    Character Building in Physics Learning for Indonesia Children .................... 129

    ABSTRACT COLLECTIONS ................................................................................................ 140

    AbstractTopic : Biology ...................................................................................................... 141

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    Toxicity Tests Custard Apple Seed Extract (Annona Squamosa) To Mortality Of Culex vishnui Mosquito Larvae .............................................. 141

    Synthesis and Antimicrobial Activity Profiling of Library of L-Phenylalanine Derived Ionic Liquids .............................................................. 142

    The Effect Of Addition Sucrose Concentrations Toward Weight Of Nata De Lontar (Borassus flabellifer) Linn .................................................. 143

    Tourism Development Of Lane Clean And Green With Ergo-Entrepreneurship Oriented To Increase Entrepreneurship Attitude And Public Awareness Of Environmental Conditions In Peliatan Village, Ubud, Gianyar ......................................................................... 144

    The Tolerance Improvement Of Local Soybean In Waterlogging Condition Through The Combination Of Irradiation And In Vivo Selection ....................................................................................................................... 145

    Ethyl Asetate Fraction Of Secang Cytotoxic In Cancer Cells Using In Vitro And In Silico Assay....................................................................................... 146

    Soil Nematodes On Rhizosphere Of Durian In Banjarbaru Kalimantan Selatan ........................................................................................................................... 147

    Identification Of Microscopic Fungus In Gill Of Skipjack Tuna (Katsuwonus Pelamis L.) At Traditional Markets In Singaraja - Bali .................................................................................................................................. 148

    Cytology And Histology Study Of Embryogenic Callus From Sugarcane (Saccharum officinarum L.) ......................................................... 149

    Growth Response of Jatropha Stem Graft Horizontal to the Application of Red Onion Filtrate..................................................................... 150

    An Updated Mobile Interactive Key to Species of Pratylenchus Filipjev (Nematoda: Pratylenchidae) ............................................................. 151

    Genotyping Snp rs290487 TCF7L2 Gene Using Tetra-Primer Arms-Pcr For Detection T2DM In Batak Ethnic...................................................... 152

    Characteristics Of Synthetic Seeds Of Two Medicinal Plants........................... 153 The Effect Of Addition Sucrose Concentrations Toward Weight Of

    Nata De Lontar (Borassus flabellifer) Linn .................................................. 154 Potential of Yellowfin tuna catch in East Java-Indian ocean based on

    length frequency and age distribution........................................................... 155 Comparison Between The Antibacterial Activities Of Essential Oils Of

    Clove Flower, Green Betel Leaf, Red Betel Leaf Againts Propionibacterium Acnes .................................................................................... 156

    The Formation Of Mini Illustrated Dictionary Of Rare Plants In The Village Forest Of Penglipuran, Bangli, Bali ............................................................... 157

    Abstract Topic : Biology Education .............................................................................. 158

    Stem Education As The Innovation Of Science Learning ................................... 158

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    Portfolio Enhances Creative Thinking Of Undergraduate Biology Students ........................................................................................................................ 159

    E-Learning Development Based On Schoology About Virus Material For Student Class X SMAN 1 Pulau Punjung ................................................ 160

    The Profile Of Science Education Problem In West Sumatera And Surroundings .............................................................................................................. 161

    Abstract Topic : Chemistry ............................................................................................... 162

    Larvacidal Activities Of Crude Ethanol Extracts Of Annona Squamosa Seeds From Lombok And Bali Against Aedes aegypti ............................ 162

    Proximate Analysis Of Biofuel Pellet From Pig Manures And Wood Waste.............................................................................................................................. 163

    Evaluation and Characterization of Anti-Acne Nanoemulsion of Ethyl Acetate Extract from Mangosteen Pericarp (Garcinia mangostana L.) with Virgin Coconut Oil (VCO) and Olive Oil (Oleum olivae) ........................................................................................................... 164

    Optimization Gelling Agent Viscolam Smc 20, Carbopol 940, And Xanthan Gum As Nanoemulgel Base Anti Acne Of Mangosteen Pericarp Extract (Garcinia mangostana Linn)............................................ 165

    Antioxidant Activity Test Fractions of Mangosteen (Garcinia mangostana L.) Pericarp Using DPPH Method ........................................... 166

    Species And Chemical Diversity Of Balinese Phyllidid Nudibranch ............. 167 Bioprospecting Of The Balinese Marine Sponges And Nudibranchs ........... 168 Synthesis And Characterization Of Chitosan-Alginat Crosslinked Poly

    (Vinyl Alcohol) Membranes ................................................................................ 169 Landfill Leachate Degradation By TiO2-Immobilised White Cement .......... 170 Vegetation Covering Land And Bulk Density Of The Soil On Public

    Green Space In Singaraja City ............................................................................. 171 Cholesterol Biosensor Based On Multi Enzymes Immobilized Onto Silicon Porous ......................................................................................................................... 172

    Preparation of Dye Sensitized Solar Cell (DSSC) Using Isolated Anthocyanin From Fruit Sat (Melastoma malabathricum L) Dicopimented With Salicylic Acid As Dye..................................................... 173

    Synthesize And Characterization Of Composite Hydrogel Based On Bacterial Cellulose-Extract Leaf Gambir (Uncaria gambir Roxb) ..... 174

    Chitosan Product as Bioadsorbent of Mercury Metal in Bone River Province of Gorontalo ............................................................................................ 175

    Characterization and Analysis of the Molecular Weight of Corn Corbs Microcrystalline Cellulose (MCC) Fibers Using Mass-Spectrometry Methods .......................................................................................... 176

    Abstract Topic : Chemistry Education ........................................................................ 177

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    The Future Views Of Science Teachers Curriculum Development In Indonesia ...................................................................................................................... 177

    Conceptual Change in Colloid Concepts: Case Study of Chemistry Learning ........................................................................................................................ 178

    Implementation of TripleChem learning model to improve the scientific work skills of prospective teachers in organic chemistry lectures ................................................................................................... 179

    Reflective Learning Improve Learning Activities And Achievements Of Students .................................................................................................................. 180

    Abstract Topic : Computational Sciences .................................................................. 181

    Classification Of Breast Cancer Using Wrapper And Naïve Bayes Algorithms ................................................................................................................... 181

    Abstract Topic : Computer Science............................................................................... 182

    Comparison of K-Means with Fuzzy C-Means Method for Selection of Concentration at Udayana University's Information Technology Department ................................................................................................................. 182

    Development of Mobile Application to Preserve Cultural Heritage based on CIDOC Metadata Standard ............................................................... 183

    Ontology Implementation on Open Educational Resources Case Study : Garsupati.................................................................................................................... 184

    Abstract Topic : Engineering ........................................................................................... 185

    Rule-based Automatic Leveling of Problems Difficulties in Bloom's Taxonomy-Based Serious Game for Authentic Assessment of Mathematics Learning ........................................................................................... 185

    Abstract Topic : Environmental Science .................................................................... 186

    The Impact of Human Activities on Chromophoric Dissolved Organic Matter (CDOM) Variability in A Shallow River .......................................... 186

    Material-Energy Use and Carbon Emission of Tofu Home Industry ............ 187 Abstract Topic : Life Science ............................................................................................ 188

    The Development of Cladophora Cellulose As Gelling Agent of Mask Gel Peel-Off .................................................................................................................. 188

    Formulation Of The Purple Sweet Potato Body Scrub ........................................ 189 In Silico Andrographolide From Sambiloto (Andrographis Paniculata

    (Burm F.)Ness.) As Anti-Colon Cancer Through Inhibition Cox-2 ... 190 Anti-Breast Cancer Activity Screening Of Peonidin Purple Sweet

    Potato By In Silico Study ....................................................................................... 191 The formulation of Purple Sweet Potato Extract for Bio-sunblock

    Lotion ............................................................................................................................. 192

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    The Bio-Mask Peel Off From The Ethanol Purple Sweet Potato ..................... 193 Expression Pattern of Drought-Responsive Genes in Burley Tobacco

    under in vitro Water Deficit ................................................................................ 194 Abstract Topic : Marine Science ..................................................................................... 195

    Coral Recuitment on Lembongan Island, Nusa Penida, Bali ............................. 195 α-Sutte Indicator is a New Approach to Forecasting Data ................................ 196 The Study About Pelos Community Structure And Their Contribution

    On Demersal Fisheries At Mangrove Ecosystem In Teluk Banyuwedang, Buleleng, Bali ............................................................................. 197

    Abstract Topic : Mathematics .......................................................................................... 198

    Joint Bayesian Face Recognition By Random Effect Model .............................. 198 Comparative Analysis of Three MCMC Methods For Estimating

    GARCH Models ........................................................................................................... 199 Survival Regression Analysis (Case: Factors Affecting The Healing

    Rate Of Dengue Hemorrhagic Fever Patients) ........................................... 200 Value Of Perfect Information In Stock Picking ........................................................ 201 On super (a, d)-edge-antimagic total labeling of Mӧbius ladder .................... 202 Graceful Labeling For Open Superstar of Complete Bipartite Graphs

    S2(t.Km,n) ........................................................................................................................ 203 Some Classes of Edge Anti-Magic Graphs .................................................................. 204 On Modeling and Pricing Premium Contracts of Rainfall Index-Based

    Agricultural Insurances: A Stochastic Weather Generator Simulation Approach .............................................................................................. 205

    Abstract Topic : Mathematics Education ................................................................... 206

    Effectiveness of Problem-Based Learning Process to Optimization of Student Learning Result on Currency Regression Analysis ................ 206

    The Relationship Between Learning Motivation and Student’s Performance on Analytical Geometry’s Subject ........................................ 207

    Scaffolding in Problem Based Learning to Increase Students’ Achievements in Linear Algebra ....................................................................... 208

    Types Of Student Errors In Solving Mathematical Problems .......................... 209

    From Puzzle To Problem Posing .................................................................................... 210 Assessing By Doing: A Balinese Culture Based Assessment ............................. 211 Improvement Of Student’s Mathematical Communication Using M-

    Apos Approach .......................................................................................................... 212 Designing Picture Story “The Friendship Of Cathy And Doggy” In

    Tangram Context For The Second Grade Students Of Elementary School ................................................................................................... 213

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    Developing Multimedia To Help Deaf Students At Grade 7 In Learning Cartesian Coordinate System ............................................................................. 214

    An Interactive Mathematics Learning Media In Probability For Deaf Students: Define, Design And Development................................................ 215

    Establishing Number Sense In Basic Number Operation Using Realistic Mathematics Education Approach ............................................... 216

    How Deaf Students Grade 7 Solve The Real-World Math Problems: Errors Analysis with Newman Procedure ................................................... 217

    The Levels of Context Use of PISA-like Mathematics Tasks Posed by In-service Secondary Teachers ......................................................................... 218

    A Study Of Some Mistakes From The Students In Calculus Course .............. 219 Developing Pisa Like Mathematics Problems Using Scientific Context

    For Indonesian Students....................................................................................... 220 Development Of Mathematics Lesson Equipment Based On Model

    Eliciting Activities (Meas) Approach To Improve Mathematical Problem Solving Skills Of Students Class X Of Senior High School Padang ............................................................................................................ 221

    Learning Trajectory On Real Function Based On Realistic Mathematics Education To Increase High Order Thinking Skills Student’ At Sman 10 Padang ............................................................................... 222

    The Effect Of Scientific Approach And Entry Behaviour To Mathematical Critical Thinking Abilities Student’ In Junior High School At Smpn 8 Padang ..................................................................................... 223

    Analysis Of Student’s Ability In Developing Learning Materials Based On Discovery Learning For Students With Intrapersonal And Interpersonal Intelligence ................................................................................... 224

    Development of Mathematics Instruction Based APOS Theory to Promote Mathematical Reasoning Skills Junior High School Students ........................................................................................................................ 225

    The Effect Of Interaction Between The Form Of Formative Assessment And Learning Autonomy Toward Student's Achievement ............................................................................................................... 226

    Developing Concrete-Pictorial-Abstract (CPA) Strategy for Teaching Fraction ......................................................................................................................... 227

    Developing Mathematical Comic For Teaching Social Arithmetic ................ 228 Development Of Adversity Quotient Based On Balinese Local Wisdom .... 229 Development of Authentic Assessment For Problem Based Learning

    On System of Linear Equations of Two Variable. ..................................... 230 Development of Mathlet Geogebra Assisted Learning Model To

    Improve Students' Conceptual Understanding on Equations of Straight Line ............................................................................................................... 231

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    Development of Geogebra-assisted Model Eliciting Activities (MEA) to Improve the mathematical concepts of line and angle ..................... 232

    Developing Blended Learning Environment to Improve Learning Performance and Self-Reliance for Junior High School Students ...... 233

    The Implementation of Open-Ended Learning Strategy for Improving the Critical Thinking Skills of Students Grade 10 of SMAN 2 Singaraja ....................................................................................................................... 234

    Example In Argumentation Of Undergraduate Students: A Study On Mathematical Proof Construction .................................................................... 235

    Investigation on Students’ Mathematical Online Discussion: A Case Study in Grade 8 SMPN 1 Denpasar ................................................................ 236

    The Contributions of Teacher’s Competences, Mathematical Talent, and Teaching Motivation Toward Mathematics Teachers’ Performance in The Implementation of Curriculum 2013 at The Elementary School of Buleleng Sub-District ............................................... 237

    The Effect of REACT Strategy Aided by Geogebra towards Mathematical Understanding ............................................................................. 238

    Developing Graphical User Interface using MATLAB .......................................... 239 Pisa Like Problems Using Indonesian Context ........................................................ 240 Training of Learning Character Based Mathematics Learning Tools

    for Teachers Mathematics Subjects at MGMP Mathematics SMK West Sumatra Province ......................................................................................... 241

    Integrating Ethnomathematics On Open Problem Mathematics Textbook For Junior High School Students .................................................. 242

    Development Of Blended Learning For Transformational Geometry Course To Improve Students’ Engagement And Competency In Semester Iv Of Mathematics Department, Undiksha .............................. 243

    Mathematical Literacy of Prospective Elementary School Teachers ........... 244 The Effect Problem Based Learning Model and Authentic Assessment

    on Mathematical Problem Solving Ability for Students Bali State Polytechnic with Covariabel Numerical Capability ..................... 245

    Exploration of Table and Graph Literacy of Statistics Student at Universitas Negeri Makassar .............................................................................. 246

    Abstract Topic : Physics ..................................................................................................... 247

    Characterization the geometry of the peat soil of Pontianak using Fractal Method........................................................................................................... 247

    The Relation Between Surface Temperature Of Fumarolic Gas With Magmatic Source Depth ........................................................................................ 248

    Analysis Of Array 2×2 Double Bi Circular Microstrip Antenna In Wi-Fi Communication System ........................................................................................ 249

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    Dielectric Properties and Bioactivity of PVA/PEG/TiO2 Fibers for Capasitive Based Body Sensor ........................................................................... 250

    In Situ Fabricaton on CA-AgNp/ITO Film from Natural Water Hyacinth for Electrical Storage Application. ............................................... 251

    Synthesis Of Zn4.5S5 Compounds And Their Potential Properties .............. 252 A Forward Modeling Of Gravity Data Based On 3d Sphere Cell ..................... 253 Development Of Digital Viscometer Based On Sensor Technology And

    Microcontroller ......................................................................................................... 254 Influence Of High Energy Miling Time On Nano-Quartz Structure

    From West Sumatera.............................................................................................. 255 Testing on Porosity of Composite Material Composed by Ultra Fine

    Amorphous Silica (UFAS) From Rice Husk Using X-ray Micro Computed Tomography ........................................................................................ 256

    Correlation Of Seismotectonic Parameter And Seismic Quiescence Z-Value In West Sumatra, Indonesia ................................................................... 257

    Effect Of Sintering Temperature On Crystal Stucture And Grain Size Of Manganese Ores From West Sumatera.................................................... 258

    Abstract Topic : Physics Education .............................................................................. 259

    The Identification of the 11th Grade Students’ Prior Knowledge on Electricity Concepts ................................................................................................ 259

    The Effectiveness Of Problem-Based Hybrid Learning Model In Physics Teaching To Enhance Critical Thinking Of The Students Of Sman 1 Singaraja ................................................................................................ 260

    The Effect Of Self Regulated Learning And Direct Instruction On High School Students’ Critical Thinking And Character In Learning Physics ........................................................................................................................... 261

    Contributions Climate Schools, Achievement Motivation, and Self-Concept with Student’s Learning Science Achievement ....................... 262

    Developing Of Physics Learning Media Smoky Glass Box On Light Subject ........................................................................................................................... 263

    Development of The Dynamic Fluid Learning Materials in Setting Cooperative Learning Model Type Group Investigation ....................... 264

    Development of Student Worksheets Integrated Local Wisdom to Train Scientific Process Skill and Scientific Attitude .............................. 265

    Analysis of Problem Solving Questions on Work and Energy Materials with RASCH Model in Junior High School Students ................................. 266

    The Effectiveness of Lesson Study in Improving the Social and Personal Competence of Science teachers ................................................... 267

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    Effect Of Using Portfolio Assessment To Improve Scientific Attitude By Controlling The Prior Knowledge Of Students Learning Physics In High School ........................................................................................... 268

    Development Of Authentical Assessment Device In Learning Physics ....... 269 Development Of Electronic Learning Books With Characters

    Characterized By A Scientific Approach On Material Momentum And Harmonic Motion ............................................................................................ 270

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    COMMITTEE Advisory Board Prof. Dr. I Nengah Suparta, M.Si. (Ganesha University of Education, Indonesia) Prof. Dr. Ida Bagus Jelantik Swasta, M.Si (Ganesha University of Education, Indonesia) Dr. I Gusti Lanang Wiratma, M.Si. (Ganesha University of Education, Indonesia) Dr. ir. W.T. van Horssen (Delft University of Technology, the Netherlands) Prof. David James Young (Monash University, Australia) Dr. Natthida Rakkapao (Prince of Songkla University, Thailand) Dr. Komang Darmawan (Udayana University, Indonesia) Prof. Dr. Ch. Rini Indrati (Gajah Mada University, Indonesia) Prof. Dr. Don H. Faust (Northern Michigan University) Prof. Hassan A. El-Morshedy (Damietta University, Egypt Prof. Haydar Akca (Abu Dhabi University, United Arab Emirates) Assoc. Prof. Murk Bottema (Flinders University, Australia) Dr. Henk van der Kooij (Utrecht University, The Netherlands) Dr. Agung Lukito, M.S. (The State University of Surabaya, Indonesia) Edi Winarko, Ph.D. (Gadjah Mada University, Indonesia) Dr. Wanty Widjaja (Deakin University, Australia) Assoc. Prof. Dr. L. Michiel Doorman (Utrecht University, The Netherlands) Prof. Dr. Sabine Fechner (Paderborn University, Germany) Dr. Tran Ba Trinh (Hanoi National University Education, Vietnam) Prof. Dr. Harrie M.C. Eijkelhof (Utrecht University, The Netherlands) Scientific Committee Drs. I Wayan Muderawan, M.S.,Ph.D. Dr. rer. nat. I Wayan Karyasa, S.Pd., M.Sc. Prof. Dr. Phil I Gusti Putu Sudiarta, M.Si. Dr. rer. nat. I Gusti Ngurah Agung Suryaputra, S.T., M.Sc. I Wayan Mudianta, S.Pd., M.Phil., Ph.D. Dr. I Gede Aris Gunadi, S.Si., M.Kom. Dr. I Nyoman Sukajaya, M.T. Dr. I Wayan Sukrawarpala, M.Sc. Prof. Dr. Ketut Suma, M.S. Dr. Gede Iwan Setiabudi, S.Pd., M.Si. Prof. Dr. Ni Putu Ristiati, M.Pd. Organizing Committee Prof. Sariyasa, M.Sc., Ph.D. Ratih Ayu Apsari, M.Sc., M.Pd. Dr. Dewa Ketut Sastrawidana, M.Si. Dr. I Wayan Puja Astawa, S.Pd., M.Stat.Sci. Dr. I Gede Ari Yudasmara, M.Si. I Made Suarsana, S.Pd., M.Si. I Made Pasek Anton Santiasa, S.Pd., M.Sc. Prof. Dr. I Wayan Suastra, M.Pd.

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    WELCOME ADDRESS : CHAIR OF THE COMMITTEE Om Swastyastu, Assalamualaikum Wr. Wb., Namo Buddhaya, Shalom, The honourable Rector of Universitas Pendidikan Ganesha and all Vice

    Rectors, The Dean of the Faculty of Mathematics and Natural Sciences and all Vice Deans, Distinguished Speakers and Participants, Ladies and Gentlemen,

    First of all, let us praise and thank The God Almighty for His graces bestowed on us. Allow me to heartily welcome all participants to Bali. It is my pleasure and privilege to extend our warmest welcome to all participants that present in the IConMNS, the International Conference on Mathematics and Natural Sciences whose theme is “Encountering Global Challenges through Innovation on Science, Technology, Engineering, Mathematics (STEM) and Education”. The objective of the conference is to promote the exchange of ideas and presentation of the advancements of research in the area of mathematics, natural sciences, technology, engineering, and education. The Faculty of Mathematics and Natural Sciences, Universitas Pendidikan Ganesha is proud to organized and host this conference. The conference received 128 abstract submissions, of which 109 manuscripts will be presented today. Moreover, the conference is attended by 106 non-presenter participants. To all presenters and participants, thank for your enthusiastic responses to the conference. Your present in this conference is highly appreciated. Ladies and Gentlemen, During the conference, there are four plenary talks and eight invited presentations by various experts. We are honoured to have distinguished keynote speakers: Prof. David James Young from University of the Sunshine Coast, Australia; Prof. Edward R T Tiekink from Sunway University, Malaysia; Dr. Wim T van Horssen from Delft University of Technology, the Netherlands; and Dr. Natthida Rakkapao from Prince of Songkla University, Thailand. The committee thanks all of you for having kindly and cordially accepted the invitation. The committee also thanks and appreciates all invited speakers from LPTK.

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    The conference is expected to become a forum for researchers and academicians to discuss research and to establish collaboration between them. I hope that you enjoy the scientific atmosphere of the conference and that you can greet and talk to each other, make new friends and strenghten the existing ones. Ladies and Gentlemen, The committee appreciates with gratitude all parties for their support in various forms during the preparation for and the running of the conference. On behalf of the committee and the Faculty, I acknowledge the Rector of Universitas Pendidikan Ganesha for his endless commitment and financial support. To the Rector, who will officially open the conference, I would like to extend our gratitude and appreciation. The committee has work hard to organize this conference. This conference would not be possible without dedicated and coordinated efforts of the committee members. I thank all of you for making this a reality. I wish you a fruitful conference and an exciting stay in Bali. Om, Shanti, Shanti, Shanti, Om; Wassalamualaikum Wr. Wb.; Sadhu, Sadhu, Sadhu; Shalom

    Denpasar, September 6th, 2017 Chair, Sariyasa

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    OPENING ADDRESS: RECTOR OF UNIVERSITAS PENDIDIKAN GANESHA Honorable : Dean of Faculty of Mathematics and Natural Sciences

    All Vice Rectors of Universitas Pendidikan Ganesha Keynote speakers, distinguished guests or participants of today’s conference, ladies and gentlemen

    Om Swastiastu Assalamu’alaikum warahmatullahi wa barakatuh Good morning May peace and God’s blessing be upon us all First of all, let us express our great gratitude to God the Almighty, because His Blessing has made us be in good condition or health, so that we all can be here today to attend International Conference on Mathematics and Natural Sciences (IConMNS). This conference is organized by the Faculty of Mathematics and Natural Sciences, Universitas Pendidikan Ganesha, as an attempt to share information derived from the results of studies on sciences and technology conducted by researchers from various countries. Distinguished Guests, Ladies and Gentlemen It is realized that we nowadays exist in a period of time characterized by the development of sciences, especially the development of natural sciences, and technology, which happen exponentially. It should also be admitted that there is a close interrelation between sciences and technology. This can be seen from the fact that basic sciences are hadly required for the optimal development of technology. On the other hand, an effort of developing basic sciences greatly requires continuous support from technology. With regard to this point, wise people are always in agreement that “Science without technology is fruitless and technology without science is rootless”. An important thing that needs to be kept in mind is that in developing science and technology, mathematics plays very important role. Mathematics is considered as a tool and a communication language of science and technology. This quantitative nature of mathematics increases the predictive power and control of science. This can also be put in a different way that science provides much more exact responses, which enable to have more accurate and smarter problem solving. There is a possibility that mathematics enable science to undergo development from qualitative level of science to quantitative level.

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    For the sake of being able to follow the rapid development of science and technology, having adequate mastery of mathematics, science and technology becomes the need of every individual. It should also be noted that having a good knowledge in mathematics, science, and technology is getting more and more important in work places. This is due to the fact that there are quite a large number of job opportunities pre-requesting learning capacity, logical thinking, critical thinking, decision making, cooperation, and problem solving. Considering this phenomenon, all of the countries over the world, without exception Indonesia, pay tremendous attention to the development of mathematics, science, and technology, which can be conducted through researches and education in various levels. Distinguished scientists, ladies and gentlemen, Realizing the significances of the roles of mathematics, science, and technology, I as the rector of Ganesha University of Education would strongly support and highly appreciate the carrying out of International Conference on Mathematics and Natural Sciences (ICoMNS), presenting the theme: “Encountering Global Challenges through Innovation on Science, Technology, Engineering, and Mathematics (STEM), and Education”. Through this conference, it is greatly expected that academicians and researches from different parts of the universe can mutually exchange experience, and expertise in the field of mathematics, sciences, technology, engineering and education. It is also hoped that there arises innovative ideas, the establishment of researches cooperation, and human resources sharing in terms of mathematics, sciences, technology, engineering, and education, both in national as well as international levels. Honorable guest, ladies and gentlemen It is obviously realized that today’s conference would not be meaningful without the readiness and the presence of the key-note speaker coming from variety of countries and from distinctive discipline. My high appreciation is, there for, particularly directed to the key-note speakers for your tiring long journey to make this event successful. My great thanks and appreciation is also due to all presenters for the parallel sessions, who come from various countries, universities, and different scientific disciplines in mathematics, science, technology, engineering, and education, to present the result of your studies as well as your ideas which will enrich the outcome of today’s conference. Thank you very much for your participation. It is also expected that innovative ideas as to the result of the researches and mathematics, scientific, and technological education which will be presented

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    in this international conference, will be able to give positive contribution to the improvement of the mastery of science and technology, and the improvement of the quality of mathematics, science, and technology education in various educational levels. This international conference will not come into existence without the initiation of the Faculty of Mathematics and Natural Sciences, and without the hard work of the member of today’s event committee. Consequently my thankfulness and appreciation are also devoted to the related faculty and the members of the committee. Thank you for your struggle and hard working to make this conference come true. Ladies and Gentlemen. That’s all I could say in this special and exciting opportunity. I apologize if there is any inconvenient expression in my opening speech. I end my speech by saying Om Santhi Santhi Santhi Om Assalammualaikum Waramatulahiwabarakatuh May God bless us all. Denpasar, September 6th, 2017 Rector of Universitas Pendidikan Ganesha I NYOMAN JAMPEL As requested by the conference committee, I would like to declare that the International Conference on Mathematics and Natural Sciences, today Wednesday, 6 September 2017, is officially opened.

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    RUNDOWN OF IConMNS 2017

    Day 1: Wednesday, September 6th, 2017 Time Program

    07.30 – 08.30 Registration 08.30 – 09.30 Opening Ceremony

    Welcome Dance “Sekar Jagat” Indonesia Anthem Prayer Welcoming Speech from the Chair of IConMNS Opening Speech from Rector Universitas Pendidikan Ganesha

    09.30 – 10.00 Coffee Break 10.00 – 11.00 Plenary Session 1 : Prof. David James Young (Australia) 11.00 – 12.00 Plenary Session 2 : Prof. Dr. Edward R.T. Tiekink (Malaysia) 12.00 – 13.00 Lunch 13.00 – 13.30 Parallel Session (Invited Speaker) 14.00 – 14.15 Parallel Session 14.15 – 14.30 Parallel Session 14.30 – 14.45 Parallel Session 14.45 – 15.00 Parallel Session 15.00 – 15.30 Coffee Break 15.30 – 15.45 Parallel Session 15.45 – 16.00 Parallel Session 16.00 – 16.15 Parallel Session 16.15 – 16.30 Parallel Session 16.30 – 16.45 Parallel Session 15.45 – 17.00 Parallel Session

    Day 2 :Thursday, September 7th, 2017

    Time Program 07.00 – 08.00 Registration 08.00 – 09.00 Plenary Session 3 : Dr. ir. W.T. van Horssen (The Netherland) 09.00 – 10.00 Plenary Session 4 : Dr. Natthida Rakkapao (Thailand) 10.00 – 10.30 Coffee Break 10.30 – 10.45 Parallel Session 10.45 – 11.00 Parallel Session 11.00 – 11.15 Parallel Session 11.15 – 11.30 Parallel Session 11.30 – 11.45 Parallel Session 11.45 – 12.00 Parallel Session 12.00 – 13.00 Lunch 13.00 – 13.15 Parallel Session 13.15 – 13.30 Parallel Session 13.30 – 13.45 Parallel Session 13.45 – 14.00 Parallel Session 14.00 – 14.15 Closing ceremony

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    PARALLEL SESSION SCHEDULE OF ICONMNS 2017

    Day 1: Wednesday, September 6 th, 2017 ROOM 1 Moderator : I Made Sutajaya

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 1

    Herbert Sipahutar

    13.30 – 13.45

    IConMNS 4 Dewi Kurnianingsih Arum Kusuma Hastuti

    Synthesis and Antimicrobial Activity Profiling of Library of L-Phenylalanine Derived Ionic Liquids

    13.45 – 14.00

    IConMNS 36 Triono Saputro The tolerance improvement of local soybean in waterlogging condition through the combination of irradiation and in vivo selection

    14.00 – 14.15

    IConMNS 96 Azwir Anhar Growth Response of Jatropha Stem Graft Horizontal to the Application of Red Onion Filtrate

    14.15 – 14.30

    IConMNS 106 Syamsurizal Genotyping Snp rs290487 TCF7L2 Gene Using Tetra-Primer Arms-Pcr For Detection T2dm In Batak Ethnic

    14.30 – 14.45

    IConMNS 117 Wirdhatul Muslihatin

    Characteristics of synthetic seeds of two medicinal plants

    14.45 – 15.00

    IConMNS 123 Dewi Hidayati Potential of Yellowfin tuna catch in East Java-Indian ocean based on length frequency and age distribution

    15.00 – 15.30 Coffee Break

    15.30 – 15.45

    IConMNS 122 Ni Luh Putu Manik Widiyanti

    The Effect Of Addition Sucrose Concentrations Toward Weight Of Nata De Lontar (Borassus flabellifer)Linn

    15.45 – 16.00

    IConMNS 2 Ni Putu Ristiati Toxicity Tests Custard Apple Seed Extract (Annona squamosa) To Mortality Of Culex Vishnui Mosquito Larvae

    16.00 – 16.15

    IConMNS 14 I Made Sutajaya

    Tourism Development Of Lane Clean And Green With Ergo-Entrepreneurship Oriented To Increase Entrepreneurship Attitude And Public Awareness Of Environmental Conditions In Peliatan Village, Ubud, Gianyar

    16.15 – 16.30

    IConMNS 66 Ni Putu Linda Laksmiani

    Ethyl Asetate Fraction Of Secang Cytotoxic In Cancer Cells Using In Vitro And In Silico Assay

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    Time ID Presenter Title 16.30 – 16.45

    IConMNS 67 Dinda Novianita

    Soil Nematodes On Rhizosphere Of Durian In Banjarbaru Kalimantan Selatan

    16.45 – 17.00

    IConMNS 70 Ida Ayu Putu Suryanti

    Identification Of Microscopic Fungus In Gill Of Skipjack Tuna (Katsuwonus pelamis L.) At Traditional Markets In Singaraja - Bali

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    Day 1: Wednesday, September 6 th, 2017 ROOM 2 Moderator : Sartika Tangguda

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 2

    Munzil Students' Interaction Pattern in Online Learning : A Study at Educational Chemistry Department, State University of Malang

    13.30 – 13.45

    IConMNS 97 Ardi E-Learning Development Based On Schoology About Virus Material For Student Class X SMAN 1 Pulau Punjung

    13.45 – 14.00

    IConMNS 118 Lufri The Profile Of Science Education Problem In West Sumatera And Surroundings

    14.00 – 14.15

    IConMNS 121 Eko Prasetyo Kuncoro

    Material-Energy Use and Carbon Emission of Tofu Home Industry

    14.15 – 14.30

    IConMNS 114 Nurul Jadid, Erma Estiasih

    Expression Pattern of Drought-Responsive Genes in Burley Tobacco under in vitro Water Deficit

    14.30 – 14.45

    IConMNS 69 Ida Bagus Jelantik Swasta

    The Study About Pelos Community Structure And Their Contribution On Demersal Fisheries At Mangrove Ecosystem In Teluk Banyuwedang, Buleleng, Bali

    14.45 – 15.00

    IConMNS 39 Yuliana Wahyu Stem Education As The Innovation Of Science Learning

    15.00 – 15.30 Coffee Break

    15.30 – 15.45

    IConMNS 89 Hadi Suwono Portfolio Enhances Creative Thinking Of Undergraduate Biology Students

    15.45 – 16.00

    IConMNS 13 Dyah Aryani Sartika

    Formulation Of The Purple Sweet Potato Body Scrub

    16.00 – 16.15

    IConMNS 16 Kadek Rio Reynaldi

    In Silico Andrographolide From Sambiloto (Andrographis Paniculata (Burm F.) Ness.) As Anti-Colon Cancer Through Inhibition Cox-2

    16.15 – 16.30

    IConMNS 18 Made Irma Widiastari

    Anti-Breast Cancer Activity Screening Of Peonidin Purple Sweet Potato By In Silico Study

    16.30 – 16.45

    IConMNS 22 Ni Komang Dewi Triastuti

    The formulation of Purple Sweet Potato Extract for Bio-sunblock Lotion

    16.45 – 17.00

    IConMNS 23 Kadek Sintia Deviyanthi

    The Bio-Mask Peel Off from the ethanol purple sweet potato

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    Day 1: Wednesday, September 6 th, 2017 ROOM 3 Moderator : I Wayan Mudianta

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 3

    I Wayan Karyasa

    Silicon Chemistry for Sustainable Development of Rice Agriculture

    13.30 – 13.45

    IConMNS 126 Ananda Putra Synthesize And Characterization Of Composite Hydrogel Based On Bacterial Cellulose-Extract Leaf Gambir (Uncaria gambir Roxb.)

    13.45 – 14.00

    IConMNS 10 I Wayan Muderawan

    Larvacidal Activities Of Crude Ethanol Extracts Of Annona Squamosa Seeds From Lombok And Bali Against Aedes aegypti

    14.00 – 14.15

    IConMNS 1 Wayan Subagia The Future Views Of Science Teachers Curriculum Development In Indonesia

    14.15 – 14.30

    IConMNS 71 I Nyoman Suardana

    Reflective Learning Improve Learning Activities And Achievements Of Students

    14.30 – 14.45

    IConMNS 15 Luh Putu Ayu Lakshemini Oka

    Proximate Analysis Of Biofuel Pellet From Pig Manures And Wood Waste

    14.45 – 15.00

    IConMNS 27 Tiara Maharani Evaluation and Characterization of Anti-Acne Nanoemulsion of Ethyl Acetate Extract from Mangosteen Pericarp (Garcinia mangostana L.) with Virgin Coconut Oil (VCO) and Olive Oil (Oleum olivae)

    15.00 – 15.30 Coffee Break

    15.30 – 15.45

    IConMNS 28 Made Ririn Sutharini

    Optimization Gelling Agent Viscolam Smc 20, Carbopol 940, And Xanthan Gum As Nanoemulgel Base Anti Acne Of Mangosteen Pericarp Extract (Garcinia Mangostana Linn.)

    15.45 – 16.00

    IConMNS 30 Ida Ayu Putu Suryantari

    Antioxidant Activity Test Fractions of Mangosteen (Garcinia mangostana L.) Pericarp Using DPPH Method.

    16.00 – 16.15

    IConMNS 32 Ni Wayan Martiningsih

    Species And Chemical Diversity Of Balinese Phyllidid Nudibranch

    16.15 – 16.30

    IConMNS 40 I Wayan Mudianta

    Bioprospecting Of The Balinese Marine Sponges And Nudibranchs

    16.30 – 16.45

    IConMNS 50 Ni Putu Sri Ayuni

    Synthesis And Characterization Of Chitosan-Alginat Crosslinked Poly (Vinyl Alcohol) Membranes

    16.45 – 17.00

    IConMNS 53 Ni Wayan Yuningrat

    Landfill Leachate Degradation By Tio2-Immobilised White Cement

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    Day 1: Wednesday, September 6 th, 2017 ROOM 4 Moderator : I N Sukajaya

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 4

    Syarifuddin Side

    A SIRS Model for Transformassion of Dengue Fever Disease in South Sulawesi

    13.30 – 13.45

    IConMNS 47 I. N. Sukajaya Rule-based Automatic Leveling of Problems Difficulties in Bloom's Taxonomy-Based Serious Game for Authentic Assessment of Mathematics Learning

    13.45 – 14.00

    IConMNS 99 I Nengah Suparta

    Some Classes of Edge Anti-Magic Graphs

    14.00 – 14.15

    IConMNS 11 Nanang Susyanto

    Joint Bayesian Face Recognition By Random Effect Model

    14.15 – 14.30

    IConMNS 35 Didit B. Nugroho

    Comparative analysis of three MCMC methods for estimating GARCH models

    14.30 – 14.45

    IConMNS 41 Suwardi Annas

    Survival Regression Analysis (Case: Factors Affecting The Healing Rate Of Dengue Hemorrhagic Fever Patients)

    14.45 – 15.00

    IConMNS 48 Media Rosha Value Of Perfect Information In Stock Picking

    15.00 – 15.30 Coffee Break

    15.30 – 15.45

    IConMNS 78 I Made Dendi Maysanjaya

    Classification Of Breast Cancer Using Wrapper And Naïve Bayes Algorithms

    15.45 – 16.00

    IConMNS 92 I Nyoman Budayana

    Graceful Labeling For Open Superstar of Complete Bipartite Graphs S^2(t.K_{m,n})

    16.00 – 16.15

    IConMNS 75 Putu Kartika Dewi

    On super (a, d)-edge-antimagic total labeling of Mӧbius ladder

    16.15 – 16.30

    IConMNS 120 Komang Dharmawan

    On Modeling and Pricing Premium Contracts of Rainfall Index-Based Agricultural Insurances: A Stochastic Weather Generator Simulation Approach

    16.30 – 16.45

    IConMNS 68 Desy Purnami Singgih

    Comparison of K-Means with Fuzzy C-Means Method for Selection of Concentration at Udayana University's Information Technology Department

    16.45 – 17.00

    IConMNS 128 I Ketut Resika Arthana

    Development of Mobile Application to Preserve Cultural Heritage based on CIDOC Metadata Standard

    17.00 – 17.15

    IConMNS 135 I Ketut Resika Arthana

    Implementation Ontology on Open Educational Resource Case Study : Garsupati

    http://www.undiksha.ac.id/http://www.undiksha.ac.id/http://unp.ac.id/http://www.rey1024.com/http://www.rey1024.com/http://www.rey1024.com/http://www.rey1024.com/

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    Day 1: Wednesday, September 6 th, 2017 ROOM 5 Moderator : Gede Suweken

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 5

    Sufyani Prabawanto

    Didactical Design of Integers : An Elemtary School Teachers Creation Viewed from Theory of Didactical Situation

    13.30 – 13.45

    IConMNS 20 I Made Mariawan

    Types Of Student Errors In Solving Mathematical Problems

    13.45 – 14.00

    IConMNS 133 Arif Tiro Exploration Of Table And Graph Literacy Of Statistics Student At Universitas Negeri Makassar

    14.00 – 14.15

    IConMNS 57 Ratu Ilma Indra Putri

    Developing Pisa Like Mathematics Problems Using Scientific Context For Indonesian Students

    14.15 – 14.30

    IConMNS 63 Arnellis Learning Trajectory On Real Function Based On Realistic Mathematics Education To Increase High Order Thinking Skills Student’ At Sman 10 Padang

    14.30 – 14.45

    IConMNS 64 Elita Jamaan The Effect Of Scientific Approach And Entry Behaviour To Mathematical Critical Thinking Abilities Student’ In Junior High School At Smpn 8 Padang

    14.45 – 15.00

    IConMNS 65 Atus Amadi Putra

    Analysis Of Student’s Ability In Developing Learning Materials Based On Discovery Learning For Students With Intrapersonal And Interpersonal Intelligence

    15.00 – 15.30 Coffee Break

    15.30 – 15.45

    IConMNS 72 Edwin Musdi Development of Mathematics Instruction Based APOS Theory to Promote Mathematical Reasoning Skills Junior High School Students

    15.45 – 16.00

    IConMNS 107 Armiati Training of Learning Character Based Mathematics Learning Tools for Teachers Mathematics Subjects at MGMP Mathematics SMK West Sumatra Province

    16.00 – 16.15

    IConMNS 98 I Gusti Putu Sudiarta

    Investigation on Students’ Mathematical Online Discussion: A Case Study in Grade 8 SMPN 1 Denpasar

    16.15 – 16.30

    IConMNS 113 Gede Suweken Development Of Blended Learning For Transformational Geometry Course To Improve Students’

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    Time ID Presenter Title Engagement And Competency In Semester IV Of Mathematics Department, Undiksha

    16.30 – 16.45

    IConMNS 9 Made Asih The Relationship Between Learning Motivation And Student’s Performance On Analytical Geometry’s Subject

    16.45 – 17.00

    IConMNS 38 Lisnani Designing Picture Story “The Friendship Of Cathy And Doggy” In Tangram Context For The Second Grade Students Of Elementary School

    17.00 – 17.15

    IConMNS 37 Yerizon Improvement Of Student’s Mathematical Communication Using M-Apos Approach

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    Day 1: Wednesday, September 6 th, 2017 ROOM 6 Moderator : Ratih Ayu Apsari

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 6

    I Made Astra Character Building in Physics Learning for Indonesia Children

    13.30 – 13.45

    IConMNS 43 Surya Pujawan

    An Interactive Mathematics Learning Media In Probability For Deaf Students: Define, Design And Development

    13.45 – 14.00

    IConMNS 44 Ratih Ayu Apsari

    Establishing Number Sense In Basic Number Operation Using Realistic Mathematics Education Approach

    14.00 – 14.15

    IConMNS 56 Dewi Murni A Study Of Some Mistakes From The Students In Calculus Course

    14.15 – 14.30

    IConMNS 60 Irwan Development Of Mathematics Lesson Equipment Based On Model Eliciting Activities (Meas) Approach To Improve Mathematical Problem Solving Skills Of Students Class X Of Senior High School Padang

    14.30 – 14.45

    IConMNS 73 Gusti Ayu Mahayukti

    The Effect Of Interaction Between The Form Of Formative Assessment And Learning Autonomy Toward Student's Achievement

    14.45 – 15.00

    IConMNS 81 I Made Ari Purwadi

    Developing Concrete-Pictorial-Abstract (CPA) Strategy For Teaching Fraction

    15.00 – 15.30 Coffee Break

    15.30 – 15.45

    IConMNS 82 Putri Anugrah Cahya Dewi

    Developing Mathematical Comic For Teaching Social Arithmetic

    15.45 – 16.00

    IConMNS 83 Kadek Mira Pratiwi

    Development Of Adversity Quotient Based On Balinese Local Wisdom

    16.00 – 16.15

    IConMNS 84 Noni Dita Septianti

    Development Of Authentic Assessment For Problem Based Learning On System Of Linear Equations Of Two Variable.

    16.15 – 16.30

    IConMNS 85 Ni Made Yuning Sari Parwati

    Development Of Mathlet Geogebra Assisted Learning Model To Improve Students' Conceptual Understanding On Equations Of Straight Line

    16.30 – 16.45

    IConMNS 87 Made Dwi Savitri

    Development Of Geogebra-Assisted Model Eliciting Activities (MEA) To Improve The Mathematical Concepts Of Line And Angle

    16.45 – 17.00

    IConMNS 111

    I Putu Pasek Suryawan

    Integrating Ethnomathematics On Open Problem Mathematics Textbook For Junior High School Students

    17.00 – 17.15

    IConMNS 24 Rai Sujanem The Effectiveness Of Problem-Based Hybrid Learning Model In Physics Teaching To Enhance Critical Thinking Of The Students Of Sman 1 Singaraja

    http://[email protected]/

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    Day 1: Wednesday, September 6 th, 2017 ROOM 7 Moderator : Putu Widiarini

    Time ID Presenter Title 13.00 – 13.30

    Invited Speaker 7

    Yohandri Development Of Low Sidelobe Level Array Antenna

    13.30 – 14.00

    Invited Speaker 8

    Markus Diantoro

    Green Electronic And Energy Harvesting Using Natural Organics Product Current Progress And Its Potential

    14.00 – 14.15

    IConMNS 79 Markus Diantoro

    Dielectric Properties And Bioactivity Of PVA/PEG/Tio2 Fibers For Capasitive Based Body Sensor

    14.15 – 14.30

    IConMNS 80 Markus Diantoro

    In Situ Fabricaton On CA-Agnp/ITO Film From Natural Water Hyacinth For Electrical Storage Application.

    14.30 – 14.45

    IConMNS 103 Yulkifli Development Of Digital Viscometer Based On Sensor Technology And Microcontroller

    14.45 – 15.00

    IConMNS 108 Ratnawulan Influence Of High Energy Miling Time On Nano-Quartz Structure From West Sumatera

    15.00 – 15.15

    IConMNS 125 Syafriani Correlation Of Seismotectonic Parameter And Seismic Quiescence Z-Value In West Sumatra, Indonesia

    15.15 – 15.45 Coffee Break

    15.45 – 16.00

    IConMNS 132 Ahmad Fauzi Effect Of Sintering Temperature On Crystal Stucture And Grain Size Of Manganese Ores From West Sumatera

    16.00 – 16.15

    IConMNS 119 Yenni Darvina Development Of Electronic Learning Books With Characters Characterized By A Scientific Approach On Material Momentum And Harmonic Motion

    16.15 – 16.30

    IConMNS 51 Ni Made Pujani

    The Relation Between Surface Temperature Of Fumarolic Gas With Magmatic Source Depth

    16.30 – 16.45

    IConMNS 109 Putu Widiarini

    Testing On Porosity Of Composite Material Composed By Ultra Fine Amorphous Silica (UFAS) From Rice Husk Using X-Ray Micro Computed Tomography

    16.45 – 17.00

    IConMNS 52 Putu Artawan Analysis Of Array 2x2 Double Bi Circular Microstrip Antenna In Wi-Fi Communication System

    17.00 – 17.15

    IConMNS 88 Astrini D. Kusumawati

    Synthesis Of Zn4.5s5 Compounds And Their Potential Properties

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    Day 2: Thursday, September 7 th, 2017 ROOM 1 Moderator : Septian Eka Adistha Putra

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 76 Fitri Damayanti

    Cytology And Histology Study Of Embryogenic Callus From Sugarcane (Saccharum Officinarum L.)

    10.45 – 11.00

    IConMNS 101 Abdul Gafur An Updated Mobile Interactive Key To Species Of Pratylenchus Filipjev (Nematoda: Pratylenchidae)

    11.00 – 11.15

    IConMNS 124 Ni Luh Putu Vidya Paramita

    Comparison Between The Antibacterial Activities Of Essential Oils Of Clove Flower, Green Betel Leaf, Red Betel Leaf Againts Propionibacterium Acnes

    11.15 – 11.30

    IConMNS 12 W.S. Deviana The Development of Cladophora cellulose as gelling agent of mask gel peel-off

    11.30 – 11.45

    IConMNS 136 Nyoman Wijana

    The Formation Of Mini Illustrated Dictionary Of Rare Plants In The Village Forest Of Penglipuran, Bangli, Bali

    12.00 – 13.00 Lunch

    Day 2: Thursday, September 7 th, 2017 ROOM 2 Moderator : Putu Kartika Dewi

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 19 Dodik Prasetia Coral Recuitment on Lembongan Island, Nusa Penida, Bali

    10.45 – 11.00

    IConMNS 49 Ansari Saleh Ahmar

    α-Sutte Indicator is a New Approach to Forecasting Data

    11.00 – 11.15

    IConMNS 61 Zainuddin Development of The Dynamic Fluid Learning Materials in Setting Cooperative Learning Model Type Group Investigation

    11.15 – 11.30

    IConMNS 62 Syubhan Annur

    Development of Student Worksheets Integrated Local Wisdom to Train Scientific Process Skill and Scientific Attitude

    11.30 – 11.45

    IConMNS 77 Mustika Wati Analysis of Problem Solving Questions on Work and Energy Materials with RASCH Model in Junior High School Students

    12.00 – 13.00 Lunch

    http://ansarisaleh.web.id/http://ansarisaleh.web.id/

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    Day 2: Thursday, September 7 th, 2017 ROOM 3 Moderator : I Wayan Redhana

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 59 Made Oviantari

    Vegetation Covering Land And Bulk Density Of The Soil On Public Green Space In Singaraja City

    10.45 – 11.00

    IConMNS 74 I Nyoman Tika

    Cholesterol Biosensor Based On Multi Enzymes Immobilized Onto Silicon Porous

    11.00 – 11.15

    IConMNS 130 Astin Lukum

    Chitosan Product as Bioadsorbent of Mercury Metal in Bone River Province of Gorontalo

    11.15 – 11.30

    IConMNS 131 Wiwin Rewini Kunusa

    Characterization and Analysis of the Molecular Weight of Corn Corbs Microcrystalline Cellulose (MCC) Fibers Using Mass-Spectrometry Methods

    11.30 – 11.45

    IConMNS 6 I Wayan Redhana

    Conceptual Change in Colloid Concepts: Case Study of Chemistry Learning

    11.45 – 12.00

    IConMNS 29 I Wayan Suja

    Implementation of TripleChem learning model to improve the scientific work skills of prospective teachers in organic chemistry lectures

    12.00 – 13.00 Lunch

    Day 2: Thursday, September 7 th, 2017 ROOM 4 Moderator : I Made Suarsana

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 91 Ni Luh Made Sudaryanti

    The Implementation of Open-Ended Learning Strategy for Improving the Critical Thinking Skills of Students Grade 10 of SMAN 2 Singaraja

    10.45 – 11.00

    IConMNS 95 Christina Laamena

    Example In Argumentation Of Undergraduate Students: A Study On Mathematical Proof Construction

    11.00 – 11.15

    IConMNS 100 Putu Widiartana

    The Contributions Of Teacher’s Competences, Mathematical Talent, And Teaching Motivation Toward Mathematics Teachers’ Performance In The Implementation Of Curriculum 2013 At The Elementary School Of Buleleng Sub-District

    11.15 – 11.30

    IConMNS 102 Ni Putu Urip Vidanti

    The Effect Of React Strategy Aided By Geogebra Towards Mathematical Understanding

    11.30 – 11.45

    IConMNS 105 Sri Rejeki Pisa Like Problems Using Indonesian Context

    11.45 – 12.00

    IConMNS 46 I Made Suarsana

    How Deaf Students Grade 7 Solve The Real-World Math Problems: Errors Analysis With Newman Procedure

    12.00 – 13.00 Lunch

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    Day 2: Thursday, September 7 th, 2017 ROOM 5 Moderator : Sariyasa

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 104 Sariyasa Developing Graphical User Interface using MATLAB

    10.45 – 11.00

    IConMNS 17 I Nyoman Gita

    Scaffolding in Problem Based Learning to Increase Students’ Achievements in Linear Algebra

    11.00 – 11.15

    IConMNS 8 Made Susilawati

    Effectiveness of Problem-Based Learning Process to Optimization of Student Learning Result on Currency Regression Analysis

    11.15 – 11.30

    IConMNS 31 I Made Candiasa

    From Puzzle To Problem Posing

    11.30 – 11.45

    IConMNS 33 Ni Made Sri Mertasari

    Assessing By Doing: A Balinese Culture Based Assessment

    11.45 – 12.00

    IConMNS 42 Kadek Candra Cahyadi

    Developing Multimedia To Help Deaf Students At Grade 7 In Learning Cartesian Coordinate System

    12.00 – 13.00 Lunch

    Day 2: Thursday, September 7 th, 2017 ROOM 6 Moderator : Ratih Ayu Apsari

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 127 I Gusti Putu Suharta

    Mathematical Literacy of Prospective Elementary School Teachers

    10.45 – 11.00

    IConMNS 129 I Ketut Darma

    The Effect Problem Based Learning Model and Authentic Assessment Against Increasing Understanding Concepts and Mathematical Problem Solving Ability for students Bali State Polytechnic with Covariabel Numerical Capability

    11.00 – 11.15

    IConMNS 115 Enos Taruh Development Of Authentical Assessment Device In Learning Physics

    11.15 – 11.30

    IConMNS 45 Surayanah Contributions Climate Schools, Achievement Motivation, And Self-Concept With Student’s Learning Science Achievement

    11.30 – 11.45

    IConMNS 55 Sri Hartini Developing Of Physics Learning Media Smoky Glass Box On Light Subject

    11.45 – 12.00

    IConMNS 90 I Made Gede Sukawijaya

    Developing Blended Learning Environment to Improve Learning Performance and Self-Reliance for Junior High School Students

    12.00 – 13.00 Lunch

  • International Conference on Mathematics and Natural Sciences 2017

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    Day 2: Thursday, September 7 th, 2017 ROOM 7 Moderator : I Wayan Santyasa

    Time ID Presenter Title 10.30 – 10.45

    IConMNS 94 Supriyanto A Forward Modelling Of Gravity Data Based On 3d Sphere Cell

    10.45 – 11.00

    IConMNS 3 Ketut Suma The Identification Of The 11th Grade Students’ Prior Knowledge On Electricity Concepts

    11.00 – 11.15

    IConMNS 93 Wayan Sadia The Effectiveness Of Lesson Study In Improving The Social And Personal Competence Of Science Teachers

    11.15 – 11.30

    IConMNS 21 Joko Sampurno Characterization The Geometry Of The Peat Soil Of Pontianak Using Fractal Method

    11.30 – 11.45

    IConMNS 110 Wartawan Putu Gede

    Effect Of Using Portfolio Assessment To Improve Scientific Attitude By Controlling The Prior Knowledge Of Students Learning Physics In High School

    11.45 – 12.00

    IConMNS 25 I Wayan Santyasa

    The Effect Of Self-Regulated Learning and Direct Instruction On High School Students’ Critical Thinking And Character In Learning Physics

    12.00 – 13.00 Lunch

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    IConMNS 18 Anti-Breast Cancer Activity Screening Of Peonidin Purple Sweet

    Potato By In Silico Study Made Irma Widiastari1, Kadek Rio Reynaldi1, I Gede Pradnyana Putra1, Putu

    Lia Hendrayati1, Ida Ayu Mas Sita Sanjiwani Dharmayanti1, Ni Putu Linda Laksmiani1

    1Universitas Udayana, Indonesia [email protected], [email protected],

    [email protected], [email protected], [email protected], [email protected]

    Abstract

    An acetylated antocyanine (peonidin) is one of the flavonoid group compounds contained in purple sweet potato (Ipomoea batatas) which has anticancer activity. Over-expression of Human Epidermal Receptor-2 receptor (HER-2) could induce spontaneous dimerization and autophosphorylation, and trigger the occurrence of focal adhesion kinase (FAK) activation in order to induce migratory process and breast cancer cell metastasis. Lapatinib is one of the drug which used to inhibit over-expression of HER-2. The purpose of this study was to determined the inhibition mechanism of over-expression HER-2 protein of peonidine by using in silico molecular docking method. In silico method such as molecular docking is done through stages such as validation of molecular docking method, optimization of peonidin 3D structure, docking of peonidin with HER-2 protein which refers to the binding energy parameter where the lower binding energy value indicates the stronger and stable bond between peonidin with HER-2 protein. The binding energy of peonidin was compared with native ligand’s binding energy and lapatinib’s binding energy. The result of this study was peonidine’s binding energy with HER-2 protein was -7,54 kcal/mol, while the native ligand’s binding energy and lapatinib’s binding energy with HER-2 protein were -5,77 kcal/mol and -0,56 kcal/mol. The binding energy indicates peonidine as a purified anthocyanin of purple sweet potato had potential activity as anti-breast cancer because it suppressed the excessive expression of the HER-2 protein. Keywords :peonidin, in silico, molecular docking, breast cancer, HER-2

  • ANTI-BREAST CANCER ACTIVITY SCREENING OF PEONIDIN PURPLE SWEET

    POTATO BY IN SILICO STUDY

    Made Irma Widiastari

    Pharmacy Department of Udayana University

    Proceeding IConMNS 2017

  • INTRODUCTION

    HER-2 TREATMENT?

    ACETYLATED ANTHOCYANIN

    IN SILICO METHOD

  • THEORETICALFRAMEWORK§  All anthocyanins à derivatives à single

    aromaticstructuràcyanidin.§  Other anthocyanin is formed by addition or

    substitution (hydroxyl groups, methylation,glicosylation)ofcyanidin.

    §  Anthocyanin pigment à reducing the risk ofcoronary heart disease, stroke risk, anticanceractivity, anti-inflammatory effects, improvingeyeacuity,andimprovingcognitivebehavior.

  • THEORETICALFRAMEWORK§  Cancer is a cellular disease caused by cell

    proliferationcontinuouslyanduncontrollably.§  Breastcancerproliferationprocessisinitiatedby

    overexpression of several receptor, exampleestrogen receptor (ER), progesterone receptor(PR)andc-erbB (HER-2)which isapredisposingreceptorforbreastcancer(Ecclesetal.,2001).

  • METHODOLOGY

    PreparationofHER-2Protein

    MethodValidation

    OptimationofPeonidin3DStructure

    DockingPeonidinwithHER-2Protein

  • RESULTANDDISCUSSION

    §  Proteinstructurewithoutligandanditsnativeligand

  • RESULTANDDISCUSSION§  Parameter of validation

    for docking is Root Mean Square Deviation (RMSD) value which shows the ligand irregularity rate experimentally against the crystallographic ligand on the same binding site.

    §  The RMSD value ≤ 3Å indicates that the method used is valid.

    ConformationRMSD(Å)

    EnergyBinding

    (kkal/mol)

    HydrogenBond

    1 1.42 -5.77 -2 1.88 -4.97 -

    3 5.41 -4.53 ASP863THR8624 5.12 -4.14 -5 2.68 -3.03 -6 2.90 -2.33 MET801

    7 2.48 -1.57 ARG849SER7288 2.58 -1.09 -9 3.23 -0.90 MET80110 4.62 -0.25 -

  • RESULTANDDISCUSSION

    §  The energy produced by peonidine compounds after calculating the single point of energy is 3529,799 kcal / mol and decreased to -3634.471 kcal / mol after geometry optimization aimed to minimize the energy to obtain a more stable compound (Fitriasari, 2008).

  • RESULTANDDISCUSSION The binding energy of peonidine is lower (more negative) than native ligand’s binding energy à -5.77 kcal/mol and lapatinib’s binding energy à -0.56 kcal/mol. It indicates that peonidin has a stronger and more stable bond with HER-2 protein compared to the native ligand and lapatinib.

    Conformation EnergyBinding(kcal/mol)HydrogenBond

    1 -7,54 -2 -7,51 -3 -7,49 -4 -7,42 MET8015 -7,31 ASP8636 -7,29 ASP8637 -7,29 ASP8638 -7,23 -9 -7,20 MET80110 -7,10 ASP863

  • CONCLUSION

    §  Peonidin as an acetylated anthocyanin of purple sweet potato has anti-breast cancer activity through inhibition of overexpression of HER-2 protein with a binding energy of -7.54 kcal / mol.

  • THANK YOU

  • ANTI-BREAST CANCER ACTIVITY SCREENING OF

    PEONIDIN PURPLE SWEET POTATO BY IN SILICO

    STUDYby Linda Laksmiani

    Submission date: 28-Jan-2018 08:30PM (UTC+0700)

    Submission ID: 907629803

    File name: irma_ppt.pdf (2.4M)

    Word count: 462

    Character count: 2310

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    ANTI-BREAST CANCER ACTIVITY SCREENING OF PEONIDIN PURPLE SWEET POTATO BY IN SILICO

    STUDY

    ORIGINALITY REPORT

    PRIMARY SOURCES

    www.scribd.comInternet Source

    www.elsevier.esInternet Source

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