Detection of metachronous tumors Recognition of local recurrence Follow-up Flexible endocsopy.

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Detection of metachronous tumors Recognition of local recurrence Follow-up Flexible endocsopy

Transcript of Detection of metachronous tumors Recognition of local recurrence Follow-up Flexible endocsopy.

Page 1: Detection of metachronous tumors  Recognition of local recurrence Follow-up Flexible endocsopy.

Detection of metachronous tumors

Recognition of local recurrence

Follow-up

Flexible endocsopy

Page 2: Detection of metachronous tumors  Recognition of local recurrence Follow-up Flexible endocsopy.

Benefits of colonoscopic surveillance after curative resection of CRC

290 patients, median time of follow-up, 20m Follow-up colonoscopies recommended at 6-month or 1-year

intervals 31 (10.7%) of patients were diagnosed subsequently with

intraluminal recurrence 21(67,7%) of recurrences occurred within 2 years 45.2% (14p) of the recurrences were intraluminal 38.7% (17p) were asymptomatic at the time of the detection

1967-1991 Columbia-Presbyterian Medical Centre, New York

E. Lautenbach, Ann Surg 1994.

Page 3: Detection of metachronous tumors  Recognition of local recurrence Follow-up Flexible endocsopy.

Metachronous neoplasms occur in 2,1% with median time of the diagnosis 128 months

In 66,7% of the diagnosed recurrences, asymptomatic In 88,3% of patients, no curative second-look surgery The rate of discovered metachronous tumors was similar,

irrespective of the follow-up regimen

Follow-upBenefits of colonoscopic surveillance after curative resection of CRC

E. Lautenbach, Ann Surg 1994.

Page 4: Detection of metachronous tumors  Recognition of local recurrence Follow-up Flexible endocsopy.

Resectability of LR

75% of curative resections in patients with asymptomatic LR 15,8% of curative resections in patients with symptomatic LR

Conclusion

Earlier diagnosis of the recurrence may increase likelihood of the cure

Aggressive colonoscopic surveillance in the first two years

E. Lautenbach, Ann Surg 1994.

Benefits of colonoscopic surveillance after curative resection of CRC