糖尿病足病変・壊疽 ~足の切断を免れるために~

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横浜総合病院  創傷ケアセンター メディカルディレクター 東田 隆治. 糖尿病足病変・壊疽 ~足の切断を免れるために~. 糖尿病性足病変について 本日の内容. 糖尿病と足病変の実態 糖尿病性潰瘍・壊死の治療 創傷ケアセンターの役割 糖尿病足病変の予防. 中原区医師会糖尿病病診連携の会  Sep. 8, 2009. 米国の糖尿病事情. 米国糖尿病患者 推定  2100 万人(全人口の約 7 %) 準糖尿病患者  4100 万人 糖尿病は下肢切断の第一原因 毎年 82,000 件の下肢切断 糖尿病患者の 15 %に足創傷 足創傷の 24 %が下肢切断 - PowerPoint PPT Presentation

Transcript of 糖尿病足病変・壊疽 ~足の切断を免れるために~

  • Sep. 8, 2009

  • 210074100

    82,0001524

    5 32DM Epidemic in the USA

  • 1370162022102007

  • 50.6% = 4501.6% = 7.20.6% = 2.7570

  • Moulik PK, et al: Diabetes Care 26:491-494,2003

  • J Vasc Surg 45 (Suppl S) : S5-S67, 2007

  • (ankle-brachial index; ABI)0.9 ~ 1.3ABI or Norman PE, etal: Diabetes Care 29:575-580,2006ABI or Resnick HE, etal: Circulation 109:733-739,2004

  • PAD(2001~2003ABI 0.9 263/39067.6 vs 2.7%Maeda Y: Peripheral arterial disease and diabetes. Angiology Frontier 7: 17-23, 2008

  • PADMaeda Y: Peripheral arterial disease and diabetes. Angiology Frontier 7: 17-23, 2008

  • ADAPADPAD

    ABIPAD

    51ABI50 ADA: Peripheral arterial disease in people with diabetes. Diabetes Care 26:333-341,2003

  • HbA1cPAD26Selvin E, et al: Ann Intern Med 141: 421-431,2004Norgren L, et al: J Vasc Surg 45(I Suppl): S5-S67,2007Norgren L, et al: J Vasc Surg 45(I Suppl): S5-S67,2007

  • Critical limb ischemia: CLI)

    11Wolfe JHN: Br J Surg 11: 153-157, 1986

  • Norgren L et al. Eur J Vasc Endovasc Surg 33(1 Suppl).S1, 2007

  • PADBhatt DL et al. JAMA 295: 180-189, 2006

  • CAD, CVD, PAD polyvascular disease REACH Registry Investigators: JAMA 295(2); 180-189, 2006

  • 862008227220ABI

    ABI: Rt. (-), Lt. 0.50

  • D-CT

    100% 100% 100% 100% 100%

  • SPP

  • SPPmmHg%perfusion =

  • (skin perfusion pressure; SPP)Right Foot Dorsal18 mmHgRight Foot Plantar18 mmHg

  • Right Foot Dorsal27 mmHg

  • Right Foot Dorsal60 mmHgSPPOne straight line

  • 62 200520071118, : 90%, 90% 20071217. 200712200821

  • SPP 53 mmHg 94 mmHg 58 mmHg 74 mmHgmmHg%perfusion =

  • 75

    2

  • Moist wound healing

  • (NPWT) Vacuum Assisted Closure (VAC) 23

  • NPWT (VAC)

  • 1 week 2 week

  • 5 week 7 week

  • 9 week 11 week

  • 15 week 9 month

  • 675052 652007122620081, 3/ 2008716

  • NPWT

  • Vascular laboCVTABITBISPP)

  • ABI0.550.473.5m/s5.085%75%

  • X-P CT/CTA MRI/MRA Angiography/DSA

  • 88200712201221200812564

  • 2008618

  • 710

  • NPWT

  • 10/310/24

  • 12/5

  • =77.7% (167/215)=76.9% (40/52)

    8 (10%)4 (5%)2008/6/6~2009/7/31 78 83 (31

  • ABI

  • *CTAAAACFA10cm/sdistal occlusion patternCFApost stenotic pattern