Developmental Disabilities ProjectNovember 13

Tourette Syndrome1885: George Albert Edward Gilles de la

Tourette first recorded the symptoms in the Marquis de Dampierre

A syndrome is “a group of symptoms that collectively indicate or characterize a disease, disorder, or other abnormal condition.”

Neurological disorder characterized by ticsTics can be mild or severe in nature

Tourette Syndrome Defined

Tourette Syndrome is a chronic, genetically transmitted neurochemical disorder that causes involuntary motor movements and vocalizations that are sounds, words, or a combination of the two.

Prevalence of TourettesFigures range from 1:2000 to 1:100,

approximately 0.005 to 0.03 or 0.5% to 3% of the population

Tourettes occurs more in males than femalesFemales have higher incidents of Obsessive

Compulsive Disorders

Tics DefinedRapid, involuntary, sudden movements or

vocalizations that occur rapidly at irregular intervals

Two types of tics(Motor and Vocal):1.Simple – sudden, meaningless movements of

individual muscle groups2.Complex – groups of movements using more

than one muscle group that is definite

Tic CharacteristicsOnset average is 7 years of ageDetermined in school age children Described as on urge or extreme need to

carry out actionsExternal – what can be seen

Examples: head jerking, kicking, grimacing, etcInternal - what can not be seen

Examples: abdominal tensing, jaw clicking, etc.Tourette Sydrome PSA (28 seconds)

Types of TicsThere are several types of tics. These are the

10 most common.1.Simple Motor Tics2.Complex Motor Tics3.Simple Vocal Tics4.Complex Motor Tics5.Copropraxia6.Echopraxia7.Coprolalia

Type of Tics Continued 8. Palilalia9. Echolalia10.Speech Atypicalities

Associated Disorders1. Obsessive Compulsive Disorders2. Attention Deficit Disorder (ADD)3. Attention Deficit Hyperactivity Disorder

(ADHD)

MedicationsNeuroleptics are tranquillizers that generally

suppress motor and phonic ticsExamples:HaldolOrapThorazine

Medications ContinuedAntidepressants are drugs used to treat or

prevent depression. Examples:AnafranilPaxilProzacZoloft

Medications continuedAnti-anxiety drugs help decrease ADHD

symptomsExamples:ValiumXanaxBusparTranxene

Medications continuedCentral Nervous System (CNS)Stimulants are

a substance that increases nervous excitability and alertness.

Examples:RitalinDexadrineCylert

Medications ContinuedAnti convulsants are medications that treat

and help prevent seizuresExamplesKlonipinTegretol

Medications continuedAnti hyper tensives are drugs that stop the

message from getting through to certain muscle groups.

Examples CatapressTenex

Behaviour IssuesRage is part of what an individual might

experience as a result of having to control or stop their behaviour.

Aggression is a factor that will increase the way tics present itself.

Medical BreakthroughNow known to be caused by a specific genetic

mutation as early as 2005. Research has been published in a Issue of

Science Magazine, dated October 14, 2005.Discovery of gene inversion on chromosome

13, “flip-flop”Focus on breakpoints: gene SLITRK1 (brain

growth and neuron interconnections)

Famous people that have Tourettes

Dr. Samuel Johnson Poet 1709-1784Jim Eisenreich Baseball Player 1959- Howard Hughes Actor 1905-1976Howie Mandel TV Host 1955-Dan Acroyd Actor 1952-David Beckham Soccer Player 1975-

ProfessionalsDavid E. Comings, M.DRichard P. Lifton, MD, Ph. D

Local intervieweeCarl Lockyer, founder of the Tourette Syndrome Foundation of Thunder Bay.

VideosMusic VideoEnya - TS Video, "The Tics" (2 minutes 17

Seconds)VHS Clip“I Have Tourette But Tourettes Doesn’t Have

Me”(4 minutes 51 seconds)

Tourette Syndrome Defined

Tourette Syndrome is a chronic, genetically transmitted neurochemical disorder that causes involuntary motor movements and vocalizations that are sounds, words, or a combination of the two.

InformationTourette Syndrome Foundation of CanadaNational Office

#206, 194 Jarvis StreetToronto, Ontario Canada M5B 2B7

Telephone: (416) 861-8398Toll Free: 1-800-361-3120Facsimile: (416) 861-2472

Information ContinuedTourette Syndrome Association, Inc42-40 Bell Blvd., Suite 205

Bayside, NY 11361-2820718-224-2999

Thank you