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simple instruments used by the native surgeons in theiroperations and the success of their procedures-a success,according to Mr. Curran, of 96 per cent. of their cases-is cer-tainly curious and worth reading. His account is illustratedby plates of the weapons used, and a representation of theoperation as performed by a native surgeon in the presenceof a number of native students and others. The author’sown practice as a lithotomist seems also to have beenpretty successful; and his remarks are sensible and tothe point, and calculated to encourage young surgeons torely upon common-sense rules and that amount of judg-ment and acumen which men of ordinary intelligence anddexterity ought to possess.Our Baths and Wells. The Mineral Waters of the British

Isles, with a List of Sea-bathing Places. By Joxrr 1’VTAC-PHERSON, M.D., &c. Small 8vo, pp. 205. Macmillan andCo. 1871.-It is not long since Dr. Macpherson issuedan excellent little work on the Baths and Wells of Europe,in which he gave concise and useful information relative tothe nature and the therapeutic uses of the various mineralwaters and spas of the Continent. He has now, in some200 pages, furnished the practitioner and the public witha mass of information respecting the spas in our own

country. The author deals successively with the composi-tion of various waters, the mode of selecting a suitablespa in particular ailments, and then proceeds to deal withsaline, thermal and earthy, salt, chalybeate, and sulphurwaters and wells in detail, under the three heads of Eng-land, Wales, and Scotland. Dr. Macpherson knows whathe is writing about, and his little book is a very acceptableaddition to the library of the medical practitioner, espe-cially for reference.

Sulle Dimande d’Apertura di Ntove Farmcccie in Roma, daldott. Gregorio Fedeli, q-c. Pamphlet. Rome. 1871.-This isa report to the Roman authorities, under the new order ofthings, touching the licensing of new chemists’ shops, andthe removal of some to other portions of the town. The

interest to the English reader is the bigoted tone of theauthor respecting the settling as pharmaciens, in the

eternal city, of any foreigners, or even Italians, who do notrejoice in a Roman birthright. That the practice of phar-macy should be well regulated is very wholesome, but thismay be done without illiberality. Dr. Fedeli is mistaken insupposing that pharmacy is subjected to no restriction inFrance; moreover, he does not know that in this countrythere is a Pharmaceutical Society. The author advocatesthe augmentation of the number of pharmacies in the newcapital of Italy, seeing that the population will now increaserapidly; but wishes the new licences to be equally dividedbetween natives of Rome and other Italian’subjects. He

proposes also to exclude altogether foreign pharmacists.Whether this selfish suggestion will be acted upon remainsto be seen.

THE THIRTEENTH REPORT OF THE MEDICALOFFICER OF THE PRIVY COUNCIL.

THis report is a much shorter one than usual, consistingof only some seventy pages. It is, however, a very importantone. After explaining that relapsing fever, scarlatina, andsmall-pox were the epidemics of the year, it gives a tabularsummary of 66 inquiries instituted by inspectors into theinsanitary condition of various places, and the particularsof 134 cases in which, by means of correspondence, atten-tion was directed to evils in different parts of the country.The matter calling for inquiry was invariably the existenceof some infectious disease, known mainly through theRegistrar-General’s returns. Of course the old story offouled air, fouled water, and fouled soil is told once more.

It seems, as regards the question of vaccine supply, thatthe number of applications for lymph were, in the year1870, 15,228; and that 140,927 separate supplies were sentout in reply, some of the charges equalling four and

seven pints apiece. Mr. Simon makes some specialcomments on the question of medical reform to which weshall refer particularly at another time. He declares that thePharmaceutical Society, in failing to make proper regula-tions for the keeping and selling of poisons, has been guiltyof a breach of the implied contract under which the Legisla-ture in 1868 gave powers and privileges to the Society. Thepathological work of the department has been carried onsuccessfully by Dr. Sanderson, and he contributes to theAppendix a very important report upon 11 the origin anddistribution of microzymes (bacteria) in water, and thecircumstances which determine their existence in thetissues and liquids of the living body,’’ and in continua-tion of his researches into the intimate nature of patho-logy. The object of Dr. Sanderson’s investigations was todetermine the nature and origin of microzymes, and toshow what influences their development, with a view ofgetting nearer to the understanding of the morbid processeswhich go on in the living body, and the part thatmicrozymes play in connexion therewith. Dr. Sanderson’sexperiments go to prove-(1) That so long as the germinalmatter of microzymes is excluded from animal fluids andtissues, the latter withstand decomposition for very longperiods, whilst the slightest contact with media containingthis material at once determines septic changes. Hence

microzymes excite putrefaction, if they are not the solecause, and they do so by appropriating the oxygen of thetissues. (2) That fungi are not developed from microzymes;that they are quite distinct. (3) That microzymes, unlikefungi, do not appear in superheated liquids, provided thatthe air with which they are in contact has also been super-heated. (4) That the germinal matter whence micro-zymes spring does not exist in ordinary air; but (5) thatit is derived from impure water, or from the contact ofsurfaces which have not been superheated. (6) That

microzymes are not generated spontaneously, but exist, wherethey seem to be absent, in the minutest forms. (7) Thatbacteria are deprived of their power of further developmentby thorough desiccation. Dr. Sanderson suggests as a testfor water, the addition to a small quantity of suspectedwater of one drop to five centimetres of Pasteur’s solution,in an épronvette first superheated and then filled with the so-lution, and protected by cotton wool. Iu Rix d:1Ys, if the waterbe "7.Yl1lotie," the contents of the tube become" hazy."Experiments with the London waters show that filtrationdoes little to destroy the zymotic power of water. It ap-

pears that the normal liquids and tissues of the body do not

possess zymotic properties, though "inflammatory pro-ducts" do. Dr. Sandersoia deals a heavy blow to 11 spon-taneous generation." Mr. Simon sums up his report witha reference to the unsatisfactory state of the law con-cerning the sanitary administration of the couutry, whichis so discouraging to sanitarians, and is attended with suchgreat waste of life. Mr. Simon, we are glad to find, presses

this matter home’ to the Government with telling argument.

Foreign Cleanings.RUPTURE OF THE HEART.

Tnis unusual cause of detth was observed at the Asylum.of Evreux, France, by M. V6di(. The patient, a womanaffected with dementia,, wa,s admitted March 5th., 1870. The

pulse was very irregular, but no abnormal cardiac murmurwas heard. She died suddenly on the 3rd of June, afterbeing prostrated some ttveuty-four hours, a, state contrast-

ing strongly with her usual agitation. On proceeding tothe autopsy the limbs were found cynosed, and on makinga small opening into the pericardium a jet of black bloodtook place. When this sac had been carefully slit up, theheart was found surrounded by a large clot, the thicknessbeing greater at the base than at the apex. On removingthe clot, a hole a little larger than a, shilling, round andregular, was found on the anterior surface of the rightauricle. The hole was situated on the right third of areddish-brown spot, of a square shape, and seemed to be