EPITHELIAL TISSUE

Glandular epithelia

Objectives

• Identifying glandular epithelia on the

histologic slides

• Differential diagnosis of exocrine

glands

Glandular epithelia

• Epithelial cells specialized for synthesis

and secretion

• Secretory product is stored as secretory

granules

Classification of glandular epithelia

• According to the destination of secretory

product

1. Exocrine

2. Endocrine

3. Mixed

Glandular epithelia

1. EXOCRINE GLANDS

• According to cell number:

– Unicellular: goblet cell

– Multicellular

• Secretory portion/parenchyma

• Excretory duct

Classification of exocrine glandular epithelia

Classification of exocrine glandular epithelia - Simple Glands

Classification of exocrine glandular epithelia - Compound Glands

Goblet cells – unicellular exocrine gland

Small intestine, HE, ob. 40x Small intestine, PAS, ob.40x

Intraepithelial gland, HE, ob. 40x

Nasal mucosa

Longitudinal section, ob. 10x Cross section, ob. 20x

Simple columnar epithelium

Goblet cells

Simple tubular gland

Connective tissue

http://www.lab.anhb.uwa.edu.au/mb140/

Simple tubular glands, HE

Lieberkühn glands, large intestine

Sweat gland, skin

Simple coiled tubular gland, HE, ob. 20x

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Secretory unit

Excretory duct

Stomach –gastric glands

Simple branched tubular glands, col. HE, ob. 4x, 10x

Sebaceous gland, skin

Simple acinar branched, HE, ob.10x

Epidermis

Dermis

15 Simple acinar branched, HE, ob.10x

Sebaceous gland, skin

Compound tubular, HE

Brunner glands, duodenum

Compound tubulo-acinar, HE

Parotid Gland

Serous acini, HE, ob.40x

Parotid Gland

Mucous acini, HE, ob. 40x

Sublingual Gland

Serous acini vs. Mucous acini

Mixed acini, HE, ob.40x

Sublmandibular Gland

Glandular epithelia

2. ENDOCRINE GLANDS

Nests of endocrine epithelium, HE, ob. 20x

Adenohypophysis C- capilary, -nests

Strands/cords of endocrine epithelia, HE, ob. 40x

Adrenal gland

Ross HM, Histology: A Text and Atlas, 4th ed.

arrows – capilaries

Follicles, HE, ob.60x

Thyroid

Glandular epithelia

3. MIXED GLANDS

Compound acinar, HE

Exocrine pancreas

Islet of Langerhans, HE

Endocrine pancreas