Post on 17-Dec-2015
SIMPLY SMARTER™
PATIENT MONITORING AND DIAGNOSTIC EQUIPMENT SOLUTIONS
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Medical Solutions
Introduction
Purpose• Introduce Intersil solutions for
patient monitors and medical diagnostic equipment
Objectives• Overview of several sub-blocks of
the patient monitor systems and various medical diagnostic equipment
• Present Intersil feature products with select application circuits
Content• 16 pages
Learning time• 30-40 minutes (estimated)
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Patient Monitors –High Level System
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Intersil Products
Products Highlighted•Op Amps•Data Converters•Switches and Multiplexers•RS-485/422 Interfaces•Voltage references•Digital Potentiometers (DCPs)•Real Time Clocks•PWM Controllers•Integrated FET Switching Regulators•Isolated Power•Battery Chargers•Voltage monitoring
Other Intersil Products•Ambient Light Sensor/Proximity Detector•LED Backlighting•Audio Amplifiers
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ECG / EKG
ECG signals basics
• Typically 0.05 Hz to 150 Hz bandwidth, 1mV to 10mV pp
• Systems are EMI sensitive
Analog Frontend Requirements
• Low noise at low frequency, high impedance (low leakage) components are required
– ISL28110 for low noise, high impedance body probe buffers
– ISL28217 for right leg drivers
• Other analog components:
– ISL54500 for lead switching
– ISL21009D for low power VREFs
• Accuracy depends on AC or DC coupling approach from 10-bit to 16-bit.
Power• Multi output voltage solutions for powering
processors or FPGA
– ISL9440A triple output controller and single LDO controller generates the rails for a FPGA.
– ISL80101 LDO family can reduce EMI in noise sensitive areas.
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Blood Pressure (NiBP)- Non-Invasive Blood Pressure
Pressure Sensor Basics• Strain Gauge, ROUT ≈ 5kΩ, 0-300mm
Hg Range, FSOUT= 300mV, BW = 5Hz
Analog Frontend Requirements• Low noise and gain signal
conditioning. Low noise at low frequency, high DC accuracy, low power vs. low noise
– ISL28217 or ISL28233 for low noise, high voltage for gain amplification (10x to 20x)
• Active Filters. Low pass filters for cuff pressure. Bandpass filters to capture oscillations, ISL28217 or ISL28233, use INTERSIL’S FILTER DESIGNER.
• See Intersil’s Medical Brochure for other analog components. http://www.intersil.com/literature/images/LC-097.pdf
Power• For portable monitors, efficiency
and size are the main focus. – ISL9440A, ISL9104, ISL8033 are
some of the products that can power the FPGA and also work well to generate the power to the amplifiers in the system.
http://web.transim.com/iSimFilter/Pages/DesignReq.aspx
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SpO2 – Pulse Oximetry(saturation oxygen in blood)
Pulse Oximetry Basics• Pulse Oximetry is the non-invasive
measurement of the arterial blood’s oxygen saturation.
• Detectors are needed to determine deoxygenated vs. oxygenated blood.
Analog Frontend Requirements• Diagnostic SpO2 typically uses JFET-input
op amps, or CMOS op amps are used to construct the transimpedance amplifier frontends.
– The ISL28110/210 is a precision JFET-input op amp that can be used for these applications because of its low noise and high impedance.
Power• The majority of these oximetry monitors are
portable and run from 1 or 2 cell Li-ion batteries. These are rechargeable devices.
– The ISL9220A can be used in these applications to recharge at higher efficiency with up to 2A charge current.
– The ISL9104 fully integrated 500mA Switching regulator can be used to generate a very compact switching solution because of its high switching frequency.
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Body TemperatureTemperature Sensor Basics
• Type varies for surgical, patient-care, home care. Typically either infrared, thermistor, or thermopile/ pyroelectric sensors.
• System consists of a small sensor voltage, then gain and filter signal conditioning.
Analog Frontend Requirements• Diagnostic (professional) vs. home use (ear-
type) vary. For diagnostic body temp monitors, use precision op amps for signal conditioning.
– Intersil provides several options for high DC precision, low temperature offset drift and lower power :
– For IR sensors: ISL28130 Low Cost, Low Power
– For Thermistor: ISL28217, ISL28207, ISL28218 for precision
– For Pyroelectric/Thermopile: ISL28110, ISL28133, ISL28217
Power• Making the power solution compact
with a reduced BOM is critical. – The low current switching regulators and
multi- output low current LDO’s are a good fit for power here.
ISL3232ISL4221E
SIMPLY SMARTER™
Product Specifics
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ISL28110/210: JFET-Input, Low Noise Op Amps
Feature Benefit
Low Input Bias Current: •2pA max @ room•4.5pA max @ 60°C•50pA max @ 85°C
•High input impedance sensors
•Photodiode, amperometric,
transimpedance application
Low Voltage Noise: •6nV/√Hz @ 1kHz•580 nVpp @ 0.1Hz to 10HzLow Current Noise:•9fA/√Hz @ 1kHz
•Low noise for better accuracy
and improved SNR
Precision•Low offset voltage: 300µV max•Low Drift: 1µV/°C
•Precision signal conditioning
Superior AC (Dynamic) Performance•BW = 12.5MHz•Slew Rate = 23V/µs•THD = 0.00002%
(G=1, f=1kHz, 4Vpp, RL=2kΩ)
•Ideal for high performance
instrumentation, DAQ
Operating Voltage: •9 to 40V or ±4.5V to ±20V
•Wide operating voltage range
Outstanding Noise Performance
Low Bias Current of TIA Applications
High Impedance Buffers
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Precision Low Noise JFET Operational Amplifier
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Competitive Summary
Medical Applications Pulse Oximetry ECG/EEG In Vitro – Biochemical Analyzers Anesthesia Equipment Blood Flow Measurement
Competitor A Competitor B Competitor C ISL282101
10
100
1000
10000
25C 60C 85C 125C
Ibias (pA)
ISL28210 Input Bias Current (Max)ISL28210 Input Bias Current (Max)ISL28210 Input Bias Current (Max)ISL28210 Input Bias Current (Max)ISL28210 Input Bias Current (Max)ISL28110/210 Input Bias Current (Max)
10x Better
300 fA Typical
Mfg
Max Ibias (pA)
DifferentialInput
Capacitance(pf)
Noise @ 1kHznV/rt Hz
Noise .1 to 10Hz
nVp-p BW
(MHz)Min SR (V/us)
Max Vos (uV)
Max Is (mA)
ISIL 2 8.3 6 580 12.5 20 300 2.9Comp A 75 12.5 8 2400 8 20 900 2.3Comp B 50 4 13 2100 8 20 600 2.5Comp C 10 8 6 1800 25 40 100 3Comp D 50 1 8 ** 5 14 500 4.8
ISL28110/210 Superior Low IBIAS
and Noise
Performance
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ISL28130/230/430: 1.65V to 6V Micropower Rail-Rail, Precision Amps
Feature Benefit
Precision•Low offset voltage: 40µV max•Low Offset Drift: 150nV/°C max
•DC Accuracy for 12-bit to 16-bit applications
Operating Voltage: •Rail-Rail Input and Output•1.65V to 6V Single Supply•±0.825V to ±2.75V Dual Supply
• Lowest operating voltage vs. competition, allows operation at low battery levels
Low Power•25µA max
• Low power consumption for precision
Low Voltage Noise: •1.1 µV p-p @ 0.01 Hz to 10Hz
• Ideal for high performance instrumentation, DAQ
Low Cost Precision (single/dual/quad)
• Ideal for medical consumer applications
Ear Thermometer Temperature
ISL28130
1.65V
ISL28130
0.825V
- 0.825V
Lowest Operating Voltages
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ISL9440A: Triple Output PWM Controller With a Single LDO Controller
Feature Benefit
Integration• Three fully integrated
PWM controllers and one LDO controller
• Single solution to generate three rails to power a Processor/FPGA
Separate rail control• Separate enable and
power good• Independently
programmable voltage outputs
• Allows user to power on or off each rail independent of the other rails.
• Facilitates ease of sequencing
Synchronous regulation• Each switching rail is
fully synchronous
• Gives a more efficient method of delivering power to the load
Out of Phase switching• 0°/180°/0° Phase shift
between channels
• Allows for reduction of RMS input current and voltage ripple so input capacitance can be reduced
Protection• Integrated UV/OV/OC/OT
protection
• Provides protection against various fault modes
Medical Applications ECG / EEGImaging systemsPatient monitoringDialysis machines
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ISL9220: Switching Charger for 1 & 2 Cell Li-Ion Batteries
Feature Benefit
Switching topology• Synchronous Buck Topology, with
Integrated Power FETs
• More efficient charging of 1 and 2 cell
• Li-ion batteries 90% + efficiency to optimize the charging time
Integration• Integrated FET’s for a fully Synchronous
& compact solution
•Allows for a compact solution•Fewer external components
Charging current• Up to 2A charging current
• Allows faster charging or helps to reduce charge time
VBAT = 3.6V
VBAT = 3.0V
VBAT = 4.0V
0 0.2 0.4 0.6 0.8 1 1.2 1.4 1.6 1.8 2 2.270
75
80
85
90
95Battery Charge Efficiency
Charge current (A)
Eff
icie
ncy
(%
)
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ISL9305: Compact Power Management IC Reduces Complexity
• Available in WLCSP & QFN packages• I2C interface to set voltage, set on/off
sequence and En/Disable PFM mode• 15mV Pk-Pk PFM ripple • Excellent load transient response
• Dual High Fsw Buck + Dual Low VIN LDO• 3MHz fixed switching frequency • 800 mA from the buck regulators (H
version: 1500mA)• 300mA output current from the LDOs
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ISL9103/4: Low Power Switching Regulator
• 2.5MHz/4.3MHz Synchronous Buck Regulator with up to 95% efficiency
• 500mA Buck Regulator with high switching frequency and ultrasonic mode of operation
• Low Quiescent current of 20µA IQ in PFM Mode
• 2.7V to 6V Vin range• 3% Output Accuracy Over-
Temperature and Line for Fixed Output Options
• 100% Maximum Duty Cycle for Lowest Dropout
• Discharge Output Capacitor when Disabled
• Tiny 1.6x1.6mm Package
C22.2µF
LPHASE
GND
FB
VIN
EN
INPUT:
2.7V- 6V
OUTPUT2.5V/0.4A
C12.2µF
ISL9104-2.5 1.0 uH
Tiny 1µH inductor
www.intersil.com
Closing