25 – 26 March 2014

London

Linking Academic Clinical and Commercial Worlds

© 2014 Captum Capital Limited. All worldwide rights reserved.

Post Conference Summary

SENSORS IN MEDICINE 2014

Sensor technology is having a significant impact on healthcare practice. From critical point-of-care, to diabetes monitoring, cancer and infectious disease diagnosis through to lifestyle changes for better health, sensor applications are at the fore front. Sensors in Medicine is an international conference series which brings together leading academics, clinicians and commerce to explore these exciting applications and their impact in healthcare.

This slide presentation provides a flavor of Sensors in Medicine 2014 for the benefit of those who were unable to attend, and to introduce the conference series to everyone who is considering joining us in 2015.

Michael Brand Conference Chair

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Promote innovative new commercial sensor technology

Highlight leading academic research near to commercial use

Provide a platform to showcase emerging sensor companies

Explore trends in medical applications of sensor technology

Facilitate formation of partnerships for investment and technology transfer

CONFERENCE OBJECTIVES

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THE COMMITTEE

Dr. Michael Brand Captum Capital Limited

Dr. Stuart Hendry Consultant

Dr. Danny O’Hare Imperial College, London

Dr. Michael Pringle Formerly, Siemens Healthcare Diagnostics

Prof. Chris Van Hoof imec

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VENUE

Royal Geographic Society 1 Kensington Gore, London, SW7 2AR.

Ondaatje Theatre

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The Conference took place on the entire ground floor of Lowther Lodge, built in 1874

Tuesday 25th March 8:30 am Registration & Coffee 9:00 am Introduction 9:10 am Keynote: Dr. Marc Bailey 9:45 am 1. Digital Health 1:00 pm Lunch 2:00 pm 2. Innovation Technology 5:30 pm Break 6:00 pm Reception 8:30 pm Close

Wednesday 26th March 8:30 am Registration & Coffee 9:00 am Introduction 9:10 am Keynote: Dr. Thomas Keller 9:45 am 3. Breath Analysis 1:00 pm Lunch 2:00 pm 4. Emerging Companies 5:00 pm Close

PROGRAM

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KEYNOTE: NEW SENSOR TECHNOLOGIES AND MHEALTH

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Dr. Marc Bailey Nokia

Digital Health

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Chaired by:

Prof. Chris Van Hoof Imec University of Leuven

IMPROVING PATIENT OUTCOMES THROUGH DIGITAL HEALTH

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Ingestible Sensor Integrated with Medicines

Don Cowling Proteus Digital Health

TOWARDS SMARTPHONE CONNECTED DIAGNOSTICS FOR INFECTIOUS DISEASES

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Prof. Rachel McKendry University College London

“Emerging infections and antibiotic resistance rank among the gravest threats to human health alongside global warming and terrorism”

PRACTICAL APPLICATIONS OF WEARABLE SENSORS IN CLINICAL RESEARCH

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Prof. Michael Marschollek Peter L. Reichertz Institute for Medical Informatics University of Braunschweig

SENSOR ADAPTATION FOR CONTINUOUS IN BODY AND ON BODY MONITORING

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Prof. Pankaj Vadgama Queen Mary University of London

PRINTED SENSORS FOR THE HEALTHCARE SECTOR

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Dr. Laura Lopez CETEMMSA

SENSOR DEVELOPMENT FOR MEDICAL APPLICATIONS

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Dr. Christopher Dawson The Technology Partnership

Innovation Technology

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Chaired by:

Prof. Martyn Boutelle Imperial College

Dr. Danny O’Hare Imperial College

MICROENGINEERED DEVICES FOR BIOMEDICAL RESEARCH

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Prof. Nancy Albritton University of North Carolina

DESIGNING NANOMATERIALS FOR ULTRASENISITVE BIOSENSING

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Prof. Molly Stevens Imperial College

The Stevens Group - Nanomaterials as Diagnostic Platforms www.stevensgroup.org/index.php/research/nanomaterials

MICROPROBE ARRAYS FOR MINIMALLY INVASIVE CONTINUOUS GLUCOSE MONITORING IN DERMAL INTERSTITIAL FLUID

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Dr. Sanjiv Sharma Imperial College

DROPLET MICROFLUIDICS: TOWARDS ULTRA-HIGH THROUGHPUT BIOLOGICAL EXPERIMENTATION

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Prof. Andrew deMello Swiss Federal Institute of Technology ETH Zürich

MULTIPLEXED INFECTIOUS DISEASE TESTING: SOUND POINT OF CARE DIAGNOSTICS

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Prof. Jon Cooper University of Glasgow

Panel Discussion

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Chaired by:

Dr. Michael Brand Sensor100

CHALLENGES OF CONTINUOUS IN-VIVO SENSING

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What does concentration in tissue mean? Dr. Danny O’Hare, Imperial College

What are the effects of sensor implantation on the tissue? Prof. Martyn Boutelle, Imperial College

How should you protect your sensor from tissue? Prof. Pankaj Vadgama, Queen Mary University of London

What is required to have validated your in-vivo sensor? Prof. Tony Cass, Imperial College

KEYNOTE: SENSOR OPPORTUNITIES IN MEDICINE DEVELOPMENT

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Dr. Thomas Keller Glaxo Smith Kline

Breath Analysis

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Chaired by:

Dr. Michael Pringle Formerly Siemens Healthcare Diagnostics

SENSOR BASED BREATH ANALYSIS

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Dr. Roland Pohle Siemens Corporate Research & Technology

POINT OF CARE DIAGNOSTICS BASED ON ORGANIC AND PRINTED TECHNOLOGIES

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Prof. Tony Killard University of the West of England

SPEAKER FEEDBACK

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Just to reiterate that the Sensors in Medicine was, for me, one of the most focussed and relevant meetings that I have been to in some time and I found it enormously useful and would be keen to attend on a regular basis.

Professor Tony Killard, UWE

ON THE POTENTIAL OF ION MOBILITY SPECTROMETRY FOR MEDICAL APPLICATIONS

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Dr. Wolfgang Vautz ISAS-e.V

FAIMS: A BREATHALYZER FOR DISEASE

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Billy Boyle Owlstone

Emerging Companies

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Chaired by:

Dr. Shaw Fox Sphere Medical

SMART PHONE ENABLED ACOUSTIC BIOSENSORS

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Dr. Dale Athey OJ-Bio

ELECTROCHEMICAL DETECTION OF DNA AT DIRECTLY HEATED ELECTRODES

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Dr. Lars Kruger Gensoric

Just wanted to say thank you for organizing the conference. We have had some really great follow-up discussions with potential partners. So coming to London was really worth it.

Dr. Lars Kruger, Gensoric GmbH

NOVEL PHOTONIC CHIP BASED NON-INVASIVE BIOSENSOR TECHNOLOGY

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Professor Gin Jose University of Leeds

Point of Care Diagnostics

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Chaired by:

Dr. Shaw Fox Sphere Medical

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Affordable sensors to detect microorganisms using reagentless and label-less impedance spectroscopy

Summary

• Impedance spectroscopy and low cost screen printing used to detect presence of P. aeruginosa.

• The electrodes are not modified (i.e. no reagents or labels are used)

• Significant changes occur to the impedance after 24 hrs growth of P. aeruginosa. Changes are related to the presence of phenazine electroactive metabolites such as pyocyanin, which are not produced by S. aureus, H. influenzaeor C. albicans.

• Analysing the whole impedance spectrum could result in changes that are characteristic of other microorganisms.

Further InformationContact:Andrew Ward:andrew.c.ward@strath.ac.ukProf. P. Connolly:patricia.connolly@strath.ac.ukDr. N. P. Tucker:nick.tucker@strath.ac.ukFurther Reading:Ward et al. (2014), PLoS One Vol 9 Iss 3Patents:Detection approach covered by patent: WO2009136157

Sensors in Medicine 2014, London

Example Electrode

Dr. Andrew Ward

POINT OF CARE TESTING OF NO METABOLITES

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Professor M. Gabriela Almeida Instituto Superior de Saúde Egas Moniz

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IMEL

WT

MU

*atserepi@imel.demokritos.gr

aInstitute of Nanoscience & Nanotechnology, NCSR “Demokritos”, Aghia Paraskevi, Greeceb Foundation of Biomedical Research, Academy of Athens, Greecec National Technical University of Athens, Physics Department, Athens, Greece# Current address: Nano-Group, ECS, University of Southampton, UK

Dr. Despina Moschou University of Southampton

DELIVERING A PORTABLE, QUANTITATIVE, RAPID DIAGNOSTIC SYSTEM FOR POINT OF CARE DIAGNOSTICS

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Courtney Nicholson AgPlus Diagnostics

DELEGATE FEEDBACK

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The event was excellent. Dr D F Chowdhury, Nemaura Pharma

I thoroughly enjoyed this meeting. I felt there was a good variety of speakers - I loved the Panel Discussion. The location was perfect.

Niamh Brannelly, University of the West of England

Keep [the Conference series] going! Anonymous delegate

POSTER COMPETITION

Winners

Buffer capacity of blood: a lab-on-a-chip approach Sahir Gandhi, Imperial College, London

Photonic chip enabled non-invasive glucose biosensor Tarun Kakkar, University of Leeds

Development of a CMOS-integrated tunneling magneto-resistance biosensor for lab-on-a-chip sepsis diagnostics Dr. Eike Moritz Eggeling, AIT Austrian Institute of Technology GmbH

Continuous contact-free monitoring using piezoelectric sensor Roman Karasik, Earlysense Ltd, Israel

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The Poster Competition was sponsored by: Medical Research Council Technology The four most innovative posters, judged by the delegates, each received a cash award of £200

Sahir Gandhi

EXHIBITION

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EXHIBITOR FEEDBACK

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We are very interested in attending the conference again next year as sponsors and would be even more delighted with it if we could get an opportunity to talk.

Leonie Hilliard, Scienion AG

It’s great to hear that you’ll be holding a Sensors in Medicine 2015. My colleagues Dr Heather Murton and Dr Jenny Hannant came back with nothing but praise for the conference. We expect to be able to live demos of our Handheld Molecular Diagnostic Lab by the time 2015 rolls around, so please do keep us in mind for speaker opportunities.

Maggie Love, QuantuMDx Group Limited

RECEPTION

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WORKSHOP: STARTING AND GROWING A SENSOR COMPANY Program:

Legal issues – Susan Laws, Duane Morris

Sources of finance – Michael Brand, Captum Capital

Protecting IP – Robert Carpmael, Marks & Clerk

Case study: Drinksafe – Christopher Jones, Imperial College

Partnering – Michael Pringle, formerly Siemens Healthcare Diagnostics

Networking – Tony Jones, OneNucleus

Case study: SCANurse - Anil Vaidya

Exit routes – Michael Brand, Captum Capital

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The Workshop was held on Thursday 27 March at the Department of Bioengineering, Imperial College

MEDIA PARTNERS

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Sensors in Medicine is proud to partner with:

Sensors in Medicine social networks:

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The 3rd Annual Sensors in Medicine Conference 24-25 March 2015 South Kensington, London Expressions of interest are invited from: • Speakers • Poster Exhibitors • Exhibition Sponsors • Partners • Delegates

Join the Mailing List for Program updates

ABOUT SENSOR 100

Sensor100 is a global network of people and organisations active in research, development and commercialisation of bio-sensors and chemo-sensors

The primary objective of Sensor100 is to facilitate the transfer of sensor technology from the lab to commercial use

The Sensors in Medicine Annual Conference series is organised by Sensor100

The free monthly eNewsletter is distributed by email to network members in over 70 countries worldwide

www.sensor100.com

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www.sensor100.com

m Sensor100 is managed by: Captum Capital Limited Cumberland House 35 Park Row Nottingham NG1 6EE United Kingdom t: +44 (0) 115 988 6154 www.captum.com

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For more information, contact:

Dr. Michael Brand

www.captum.com