PHRM 826 Lecture _ Skin Hair Nails Part I (1)

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Transcript of PHRM 826 Lecture _ Skin Hair Nails Part I (1)

G a i l D . N e w t o n , P h . D . , R . P h .

ASSESSMENT OF COMMON SKIN, HAIR, AND NAIL DISORDERS

LECTURE OBJECTIVES

• Recognize the signs and symptoms of common dermatological disorders.

• Identify the causes of common dermatological problems.

• Recognize dermatological signs and symptoms that warrant referral to a primary care provider.

• Given a case, determine the most likely cause of the patient’s dermatological problem.

• Given a case, determine whether or not a patient’s dermatological condition warrants referral to a primary care provider.

WHAT IS THIS?

Which of the following is a picture of poison ivy dermatitis?

A B C

CONTACT DERMATITIS

• Defined as skin eruptions that develop as a result of a substance coming into contact with the skin

• Irritant contact dermatitis (ICD) is secondary to exposure to soaps, detergents and organic compounds.

• Allergic contact dermatitis (ACD) is secondary to exposure to any substance that triggers an allergic response such as plant resins, latex and certain metals

IRRITANT CONTACT DERMATITIS

Acute ICD

Chronic ICD

IRRITANT CONTACT DERMATITIS

“New Shirt” ICD

“Lip Lickers” ICD

ALLERGIC CONTACT DERMATITIS

ACD: Nickel

CONTACT DERMATITIS

• Treatment

• Avoidance

• Antihistamines

• Topical Steroids

• Oral Steroids

• Topical Astringents

• Topical Protectants

• Referral

• Signs of Infection

• Large Area of Involvement

• Interference With Activities of Daily Living

• Extensive Swelling

HOW DO I GET RID OF THIS?

Which of the following would not require medical referral?

A B C

ACNE

• androgenic hormones

• increased sebum production

• follicle growth

• Propionibacterium acnes

ACNE

ACNE

Type 1 Comedones only; <10 lesions on the face; no lesions on the trunk; no scarring

Self-treatment

Benzoyl peroxide Salicylic acid Sulfur/resorcinol Azelaic acid Tretinoin

Type 2 Papules; 10-25 lesions on face and trunk; mild scarring

Refer to physician

Topical antibiotics

Type 3 Pustules; >25 lesions; moderate scarring

Refer to physician

Oral antibiotics Topical therapy

Type 4 Nodules or cysts; extensive scarring

Refer to physician

Isotretinoin Systemic hormones

Treatment

ACNE

• Type 1: Open Comedones Only

• Type 1: Closed Comedones Only

ACNE

• Type 2 Acne • Type 3 Acne

ACNE

• Type 4 Acne • Type 4 Acne

FUNGAL SKIN INFECTIONS

• Dermatophytoses are the most common disorders of the skin.

• The most common causes are Epidermophyton, Microsporum and Trichophyton Species.

• These may be transmitted from fomites, animals and the soil.

• The three most common types of dermatophytosis are tinea pedis, tinea corporis, and tinea cruris.

FUNGAL SKIN INFECTIONS

• Require a warm moist environment and an avenue into the stratum corneum

• Presentation is different depending upon the dermatophye and infection site

FUNGAL SKIN INFECTIONS

FUNGAL SKIN INFECTIONS

• Risk Factors

• Immunosuppression

• History of atopic dermatitis

• Warm, humid climates

• Occlusive clothing and footwear

• Obesity

FUNGAL SKIN INFECTIONS

FUNGAL SKIN INFECTIONS

FUNGAL SKIN INFECTIONS

FUNGAL SKIN INFECTIONS

• Treatment

• Astringents

• Antifungals

• Clean, dry clothing

• Prevention

• Referral

• Signs of Infection

• Large Area of Involvement

• Interference With Activities of Daily Living

• Extensive Swelling

FUNGAL SKIN INFECTIONS

• Referral

• Scalp involvement

• Nail involvement

• Immune suppression

• Multiple diseases

• Diabetes

HOW DO I GET RID OF THIS?

Which of the following would not require medical referral?

A B C

PEDICULOSIS

• Pediculosis refers to louse-borne infestations.

• There are three types of lice that are common in the US.

• Head lice (pediculosis capitis)

• Body lice (pediculosis corporis)

• Pubic lice (pediculosis pubis)

• Pubic lice can also infest other hairy areas such as the eyelashes and axilla.

• Body lice infestations can be eradicated without drug therapy.

PEDICULOSIS

• Risk Factors

• Close physical contact

• Sharing infested combs, hats, clothing, bedding, etc.

• Multiple sexual partners

PEDICULOSIS

PEDICULOSIS

PEDICULOSIS

• Treatment

• Pediculocides

• Total nit removal

• Environmental Decontamination

• Prevention

PEDICULOSIS

• Referral

• Eyelash involvement

• > 2 treatment failures

• Evidence of secondary infection

• Systemic symptoms

WHAT ABOUT MY BABIES?

•Household pets with fur must also be treated with lice.

A. True

B. False

SKIN CANCER

• There are three types of skin cancer that are common in the US.

• Basal Cell Carcinoma (BCC)

• Squamous Cell Carcinoma (SCC)

• Melanoma

• The American Cancer Society estimates that 850,000 cases of BCC, 250,000 cases of SCC and 60,000 cases of melanoma are diagnosed annually.

SKIN CANCER

• Risk Factors• Fair skin

• History of sunburn

• Excessive UV exposure

• Presence of moles

• Family History

• Personal History

SKIN CANCER

• BCC may appear as a

• pearly or waxy bump

• flat, flesh-colored or brown scar-like lesion

• single ulceration with a rolled border

SKIN CANCER

BCC BCC

SKIN CANCER

• SCC may appear as a

• firm, red nodule.

• flat lesion with a scaly, crusted surface.

SKIN CANCER

SCC SCC

SKIN CANCER

• Melanoma signs include(a)

• large brownish spot with darker speckles

• mole that changes in color, size or feel or that bleeds.

• small lesion with an irregular border and portions that appear red, white, blue or blue-black.

• dark lesions on the palms, soles, fingertips or toes, or on mucous membranes lining the mouth, nose, vagina or anus.

“ABCDE” Rule for Skin Cancer