Ocular pathologies in systemic diseases

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Basic ocular symptom in autoimmune diseases• Keratoconjunctivitis sicca• Scleritis• Nodular• No nodular

• Uveitis. Vasculitis• PUK. Peripheral Ulcerative Keratitis• Cataract formation

• Scleromalacia

Rheumatoid arthritis

Juvenile Idiopathic Arthritis

• Definition (Revisión ILAR 2001.Edmonton)

Idiopathic Arthritis in patients younger than 16 years and lasts at least 6 weeks.

• Classification

• Risk factor for uveitis

Oligo or pauciarticularPolyarticular RF + / RF-PsoriaticEnthesitis

Early onsetfemaleANA +oligoarticularHLA-DR5

Juvenile Idiopathic Arthritis

Anti-TNF-α drugs

Systemic Lupus Erythematosus (Lupus)

Wegener Granulomatosis

Sjogren syndrome

Dryness findings:

Horton arteritis. Giant cell arteritis

Marfan syndrome

Elastic Pseudoxanthoma

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Ankylosing spondylitis

Reiter syndrome/Reactive arthritis

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Digestive-Inflammatory Bowel Disease

PATOLOGÍA OCULAR EN ENFERMEDADES SISTÉMICAS

1.- Enfermedades del tejido conjuntivo2.- Espondiloartropatías3.- Digestivo-Enfermedad Inflamatoria Intestinal4.- Enfermedades multisistémicas no infecciosas5.- Infecciosas6.- Mucocutáneas7.- Cardiovasculares8 .- Endocrino-Metabolopatías9.- Miopatías10.- Neurologícas11.- Hematológicas

Sarcoidosis

Heerfordt-Waldenstrom syndrome: Uveo-parotid fever: 1.Uveitis2.Parotitis3.FeverSometimes… facial palsy

Behçet disease

Criteria for Behçet's disease:Mouth sores (oral ulcers) at least 3 times in 12 monthsAny 2 of the following:•Recurring genital sores/ulcers•Uveitis•Skin: Pustules or erythema nodosum•Positive pathergy (skin prick test)

Vogt Koyanagi Harada syndrome

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Syndrome acquired immunodeficiency (SAID)

Tuberculosis

5.- INFECCIOSAS

Toxoplasmosis

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Penfigoid syndromes

Stevens-Johnson syndrome

Atopic eczema

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Arterial hypertension

Carotid stenosis

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Diabetes mellitus

Graves Disease

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Miastenia gravis

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Multiple Sclerosis

Neurofibromatosis type I, Von Recklinghausen

Tuberous sclerosis. Bourneville disease

Sturge-Weber syndrome or Encephalotrigeminal angiomatosis

INVOLVED SYSTEMIC DISEASES

1. Connective Tissue Diseases2. Spondyloarthropathies3. Digestive-Inflammatory Bowel Disease4. Multisystem noninfectious diseases5. Infectious6. Mucocutaneous7. Cardiovascular8. Endocrine-metabolic9. Myopathies10. Neurologic Diseases11. Haematological Disease

Leucemia

Leukemic retinopathy

Masquerade symdrome

Imagen cedida por Dr. España